Any compound that inhibits oxidative phosphorylation.
ChEBI ID: 73267
| Member | Definition | Class |
|---|---|---|
| 2,4-dinitrophenol | A dinitrophenol having the nitro groups at the 2- and 4-positions. | 2,4-dinitrophenol |
| diafenthiuron | An aromatic ether that is 1,3-diisopropyl-5-phenoxybenzene in which the hydrogen atom at position 2 is substituted by a (tert-butylcarbamothioyl)nitrilo group. An agricultural proinsecticide which is used to control mites, aphids and whitefly in cotton. | diafenthiuron |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 737 (42.41) | 18.7374 |
| 1990's | 379 (21.81) | 18.2507 |
| 2000's | 318 (18.30) | 29.6817 |
| 2010's | 247 (14.21) | 24.3611 |
| 2020's | 57 (3.28) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (0.11%) | 5.53% |
| Reviews | 20 (1.08%) | 6.00% |
| Case Studies | 27 (1.46%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,796 (97.34%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 19.9526 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 73.0477 | 3 | 6 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.3708 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 36.5743 | 9 | 17 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 45.1020 | 2 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 5.3720 | 1 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 5.6987 | 2 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 43.4532 | 1 | 1 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 39.4831 | 9 | 17 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 15.4178 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 26.0703 | 6 | 12 |
| geminin | Homo sapiens (human) | Potency | 0.2818 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 30.3446 | 2 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 38.6290 | 2 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 48.6565 | 1 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 31.1027 | 2 | 4 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 41.8938 | 3 | 5 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 23.1093 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 6.6824 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 24.0874 | 2 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 39.7589 | 2 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 48.9662 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 9.8119 | 1 | 1 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 20.0775 | 2 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 77.2720 | 1 | 1 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 27.5357 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 15.8489 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 29.0929 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 63.3233 | 2 | 4 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0056 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 7.9433 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 55.0587 | 2 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 48.6565 | 1 | 2 |