Any organonitrogen heterocyclic compound based on a morphinan skeleton. These are synthetic or semi-synthetic compounds that resemble the morphinane (opioid) alkaloids in their pharmacological effects.
ChEBI ID: 83818
| Member | Definition | Role |
|---|---|---|
| hydrocodone | A morphinane-like compound that is a semi-synthetic opioid synthesized from codeine. | hydrocodone |
| naltrexone | An organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A mu-opioid receptor antagonist, it is used to treat alcohol dependence. | naltrexone |
| racemethorphan | An organic heterotetracyclic compound that is 1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene which is substituted by a methoxy group at position 6 and a methyl group at position 11. | 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,435 (16.09) | 18.7374 |
| 1990's | 2,001 (22.44) | 18.2507 |
| 2000's | 2,212 (24.80) | 29.6817 |
| 2010's | 2,455 (27.53) | 24.3611 |
| 2020's | 816 (9.15) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,377 (14.52%) | 5.53% |
| Reviews | 860 (9.07%) | 6.00% |
| Case Studies | 385 (4.06%) | 4.05% |
| Observational | 26 (0.27%) | 0.25% |
| Other | 6,836 (72.08%) | 84.16% |