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ChEBI ID: 46701
| Member | Definition | Role |
|---|---|---|
| captopril | A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug. | captopril |
| n-acetylproline | N-acetyl-L-proline | |
| pyrrolidonecarboxylic acid | An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle. | 5-oxoproline |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3,787 (39.01) | 18.7374 |
| 1990's | 3,399 (35.01) | 18.2507 |
| 2000's | 1,505 (15.50) | 29.6817 |
| 2010's | 812 (8.36) | 24.3611 |
| 2020's | 206 (2.12) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,514 (14.63%) | 5.53% |
| Reviews | 544 (5.26%) | 6.00% |
| Case Studies | 878 (8.49%) | 4.05% |
| Observational | 5 (0.05%) | 0.25% |
| Other | 7,405 (71.57%) | 84.16% |