Anal Fistula

An abnormal anatomical passage connecting the RECTUM to the outside, with an orifice at the site of drainage.

Synonym
Rectal Fistula
Anal Fistula

Excerpt	Reference
"This meningorectal fistula is the first of its kind to our knowledge to be demonstrated by microbiologic, radiologic, and pathologic studies."	( Berelowitz, BA; Breyer, MD; Malinoff, H; Walsh, TJ; Weinstein, RA, 1982)
"Perianal fistulas are the most frequent complication of, and are most often associated with, colonic disease."	( Paré, P, 2001)
"Anal fistulas are the result of chronic infection of an intersphincteric gland."	( Brunke, G; Fincke, A; Fölsch, UR; Herzig, KH; Kiehne, K; Lange, T, 2007)
"Perianal fistulas are common in Crohn's disease and often have a poor prognosis, with permanent sphincter and perineal tissue destruction."	( Kamm, MA; Ng, SC, 2008)
"Anal fistulas are common in individuals with Crohn's disease (CD)."	( Ashida, T; Fujii, H; Fukuda, Y; Kinjo, F; Koganei, K; Kosaka, T; Majima, A; Makiyama, K; Morita, N; Murakami, K; Nakamura, T; Oshitani, N; Otani, Y; Suda, T; Sugita, A; Takahama, K; Takazoe, M; Tochihara, M; Tsujikawa, T; Watanabe, M; Yamamoto, S, 2008)
"CD-associated perianal fistulas are mainly complex."	( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012)
"Successful anal fistula care in complex cases can be assisted by specialized imaging which accurately defines the site of the internal fistula opening and the fistula type."	( Aigner, F; Gruber, H; Kremser, C; Loizides, A; Pecival, D; Peer, S; Plaikner, M; Zbar, A, 2014)
"Perianal fistulas are the most common and frequently encountered types of fistulas in Crohn's disease (CD)."	( Knyazev, OV; Konoplyannikov, AG; Lischchinskaya, AA; Parfenov, AI; Ruchkina, IN; Shcherbakov, PL, 2014)
"Acquired vesico-rectal fistula is an uncommon complication of pelvic malignant tumors, surgical injury, inflammatory disorders such as tuberculosis infection, radiotherapy and less commonly diverticulum of the urinary tract."	( Abassa, KK; Kang, Z; Mao, W; Tao, J; Wei, XQ; Wen, ZF; Wu, B; Wu, ZE; Zou, Y, 2014)
"Perianal fistulas are malformations of the anorectal area."	( Adamczyk, T; Arendt, J; Kluczewska, E; Waniczek, D, 2015)
"Complex anal fistulas are responsible for pain, faecal incontinence and impaired quality of life."	( Balayssac, D; Carrier, G; Dubois, A; Faucheron, JL; Gillet, B; Pereira, B; Pezet, D, 2015)

Excerpt	Reference
"Complex perianal fistulas have a negative impact on the quality of life of sufferers and should be treated."	( García-Olmo, D; Schwartz, DA; Taxonera, C, 2009)

Excerpt	Reference
"Three high anal fistulas were treated with a carbon dioxide laser beam."	( Abramsohn, R; Bogokowsky, H; Slutzki, S, 1981)
"Asymptomatic perianal fistulas in a patient with Crohn's disease do not require treatment."	( Gordon, PH; Stein, BL, 1993)
"The conservative treatment of ano-rectal fistulae in Crohn's disease is selected according to the clinical activity and chronicity of the underlying disease."	( Brucks, U; Malfertheiner, P; Peitz, U, 1999)
"Ten dogs with perianal fistulas were treated with topical tacrolimus ointment once to twice daily for 16 weeks."	( Binnington, AG; Mathews, KA; Misseghers, BS, 2000)
"Sixty-five perianal fistula in 65 patients treated with anocutaneous advancement flap for the complex fistula, between April 1998 and December 2002, are included this prospective study."	( Aytekin, F; Erdem, E; Kabay, B; Ozden, A; Sungurtekin, H; Sungurtekin, U; Tekin, K, 2004)
"We present a male patient with a perianal fistula of 30 years' duration that had been treated on several occasions."	( Almendral, ML; Aranda, F; Echenique-Elizondo, M; Erro, JM; Ibáñez, J; Valenti, C, 2006)
"In persistent complex perianal fistulae where medical treatment initially fails, examination under anaesthesia and placement of non-cutting setons, when necessary, combined with medical treatment results in higher healing rates."	( Koutroubakis, IE, 2007)
"Complex perianal fistulas have a negative impact on the quality of life of sufferers and should be treated."	( García-Olmo, D; Schwartz, DA; Taxonera, C, 2009)
"The treatment of anal fistulas using plugs is a very promising method because of its simplicity and ability to be carried out on an ambulatory basis."	( de la Portilla, F; Díaz-Pavón, JM; Jiménez-Rodríguez, R; Rada, R; Sánchez-Gil, JM, 2011)
"Appropriate treatment of perianal fistulas in Crohn's disease (CD) involves accurate anatomic evaluation."	( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012)
"Treatment failure of anal fistula results in high re-occurrence rate."	( Antonakis, F; Dango, S; Ghadimi, MB; Hesterberg, R; Radzikhovskiy, A; Schrader, D, 2017)
"Patients undergoing BARS (hemorrhoids, anal fistula and anal fissure) were randomized at the end of surgery at a 1:1 ratio to receive first dose either CLIFE1 (n = 60) or CLIFE2 (n = 60) anorectal topical treatment, and after every 12 h for the first three postoperative days and once a day from the fourth to sixth."	( De-Oca, J; De-Ramón, B; Diaz-Munió, E; García-Montoya, E; Hereu-Boher, P; Linares-Gil, MJ; Nebot, FJ; Pérez-Lozano, P; Sanzol, R; Suñé-Negre, JM; Valls, J, 2018)
"High anal fistula (HAF) treatment is more complicated than low anal fistula treatment."	( Cheng, Y; Li, X; Shi, Y; Zheng, L; Zhi, C, 2021)
"Moreover, an anal fistula-like wound healing experiment concluded that the heterogeneous hydrogel has good slow-release properties of TTO for an accelerate healing process, this hydrogel shows great potential for the treatment of complex anal fistula wounds."	( Hu, K; Hu, W; Jia, E; Qian, M; Sun, R; Tan, Y; Zhang, Q; Zheng, W, 2023)
"Moreover, an anal fistula-like wound healing experiment concluded that the heterogeneous hydrogel has good slow-release properties of TTO for an accelerate healing process, this hydrogel shows great potential for the treatment of complex anal fistula wounds."	( Hu, K; Hu, W; Jia, E; Qian, M; Sun, R; Tan, Y; Zhang, Q; Zheng, W, 2023)
"Surgical treatment of perianal fistulae originating from Crohn's Disease (CD) or cryptoglandular abscess (CGA) remains a challenge."	( Bruder, L; Kamphues, C; Kreis, M; Lauscher, JC; Schineis, C; Warschkow, R; Weixler, B, 2023)
"Patients with complex perianal fistulae originating from CD or CGA treated with MAF were included."	( Bruder, L; Kamphues, C; Kreis, M; Lauscher, JC; Schineis, C; Warschkow, R; Weixler, B, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	105 (27.85)	23.3326
1990's	50 (13.26)	12.5806
2000's	109 (28.91)	18.1394
2010's	95 (25.20)	28.8240
2020's	18 (4.77)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	1	1
aminolevulinic acid	low	2	0
chlorine	low	7	0
salicylic acid	low	1	0
lactic acid	low	1	0
formaldehyde	low	2	0
glycerol	low	1	0
thioctic acid	low	1	0
nickel	low	1	0
niacinamide	low	1	0
phenol	low	1	0
uracil	low	1	0
urea	low	1	0
phenytoin	medium	2	1
oxyquinoline	low	1	0
acetaminophen	medium	1	1
diatrizoic acid	low	1	0
azathioprine	medium	23	2
bupivacaine	medium	5	3
cefuroxime	low	1	0
chlorpyrifos	low	1	0
ciprofloxacin	medium	17	6
clioquinol	low	1	0
diclofenac	medium	1	1
doxepin	low	1	0
fluorouracil	low	8	0
gabapentin	medium	1	1
gentamicin	medium	5	2
guaifenesin	low	2	0
ibuprofen	medium	1	1
lidocaine	medium	6	2
indomethacin	low	1	0
isoniazid	low	2	0
ketamine	medium	2	2
ketoconazole	medium	2	2
loperamide	medium	2	1
meperidine	medium	2	1
mepivacaine	low	3	0
mesalamine	low	5	0
metronidazole	medium	33	4
nitroglycerin	low	2	0
oxonic acid	low	1	0
praziquantel	low	1	0
sulfapyridine	low	1	0
sulfasalazine	low	4	0
tegafur	low	2	0
tetracaine	low	1	0
thalidomide	low	2	0
tripelennamine	low	1	0
mitomycin	low	2	0
prednisolone	medium	4	1
hydroxyproline	medium	1	1
prednisone	medium	3	1
adrenochrome	low	1	0
penicillin g	low	1	0
chloramphenicol	low	1	0
cephalothin	low	1	0
kanamycin a	low	1	0
edetic acid	low	1	0
cloxacillin	low	1	0
methylene blue	low	6	0
colchicine	low	1	0
ampicillin	low	2	0
mannitol	low	1	0
isoprene	low	4	0
methylmethacrylate	low	1	0
methylprednisolone	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
ergotamine	low	2	0
framycetin	low	4	0
diatrizoate meglumine	low	4	0
meglumine	medium	1	1
pentoxyl	low	1	0
thiazoles	low	1	0
betamethasone	low	1	0
trinitrobenzenesulfonic acid	low	1	0
deoxycytidine	low	1	0
vancomycin	low	2	0
d-alpha tocopherol	low	1	0
benperidol	low	1	0
flumethasone	low	1	0
streptomycin	low	5	0
enbucrilate	low	1	0
palladium	medium	1	1
silver	low	2	0
technetium	low	1	0
titanium	low	1	0
gadolinium	medium	8	1
gold	low	2	0
barium sulfate	medium	10	1
silver nitrate	medium	4	1
fluorine	low	1	0
chlorine	low	1	0
radon	low	1	0
trolamine salicylate	medium	3	1
iodine	low	1	0
amoxicillin	low	1	0
tobramycin	low	1	0
etoposide	low	1	0
substance p	low	1	0
diltiazem	low	1	0
piperacillin	low	1	0
nicorandil	low	2	0
fomesafen	medium	6	1
itraconazole	low	1	0
capecitabine	low	1	0
cephalosporin c	low	1	0
iridium radioisotopes	medium	1	1
fluorodeoxyglucose f18	low	5	0
ethyl 2-cyanoacrylate	low	2	0
glycidyl nitrate	low	1	0
cobalt	low	1	0
polytrimethylene carbonate	medium	3	1
methotrexate	low	1	0
beta-lactams	low	1	0
ertapenem	low	1	0
paromomycin	medium	1	1
technetium tc 99m pentetate	low	2	0
ropivacaine	low	1	0
sorafenib	low	1	0
fibrin	medium	2	1
mevalonic acid	low	1	0
inositol 3-phosphate	low	1	0
cefoxitin	medium	1	1
pentazocine	low	1	0
genipin	low	2	0
tretinoin	low	3	0
tacrolimus	medium	9	4
mycophenolic acid	low	1	0
clindamycin	medium	3	2
lycopene	low	1	0
micafungin	low	1	0
bromochloroacetic acid	low	1	0
glycosides	low	1	0
mercaptopurine	medium	14	2
curcumin	low	2	0
ethylenethiourea	low	2	0
lincomycin	low	1	0
quinine	low	1	0
indium oxine	low	1	0
nitinol	medium	4	2
apigenin	low	1	0
beta carotene	low	1	0
etretinate	low	2	0
codeine	medium	1	1
phenylephrine hydrochloride	low	1	0
hydromorphone	medium	1	1
morphine	low	11	0
barium	low	2	0
bismuth	low	1	0
butorphanol	medium	1	1
nitrofurazone	low	1	0
cefotaxime	low	1	0
rifamycin sv	low	1	0
radium	low	7	0
gadolinium dtpa	medium	5	1
shu 508	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
le 135	low	1	0
nystatin a1	low	1	0
technetium tc 99m exametazime	low	1	0
indocyanine green	medium	3	1
rifamycins	low	1	0
clove	low	1	0
acid phosphatase	low	1	0
jaw	low	1	0
bismuth subsalicylate	low	1	0
chitosan	low	2	0
ro13-9904	low	1	0
interleukin-8	low	1	0
oclacitinib	low	1	0
colistin	low	1	0
vasoactive intestinal peptide	low	1	0
tetracycline	low	3	0
chlortetracycline	low	1	0
minocycline	low	1	0
salicylates	low	3	0
s 1 (combination)	low	1	0
transforming growth factor beta	low	1	0
cyclin d1	low	1	0
technetium tc 99m sulfur colloid	low	1	0
hyaluronoglucosaminidase	low	1	0
vitamin b 12	low	1	0
cyclosporine	medium	15	4
technetium tc 99m medronate	low	3	0
muramidase	low	1	0
exudates	low	1	0
levoleucovorin	low	4	0
folic acid	low	1	0

Protein Targets (1,775)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	44	0	0	44
ATAD5 protein, partial	14	0	0	14
GLS protein	15	0	0	15
Microtubule-associated protein tau	21	0	0	21
Smad3	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	35	0	0	35
thyroid stimulating hormone receptor	21	0	0	21
nuclear receptor subfamily 1, group I, member 3	31	0	0	31
progesterone receptor	24	0	0	24
EWS/FLI fusion protein	24	0	0	25
retinoic acid nuclear receptor alpha variant 1	41	0	0	41
retinoid X nuclear receptor alpha	39	0	0	39
estrogen-related nuclear receptor alpha	46	0	0	46
estrogen nuclear receptor alpha	67	0	0	67
peroxisome proliferator activated receptor gamma	31	0	0	31
aryl hydrocarbon receptor	29	0	0	29
chromobox protein homolog 1	23	0	0	23
thyroid hormone receptor beta isoform 2	37	0	0	37
peripheral myelin protein 22	20	0	0	20
cytochrome P450 3A4 isoform 1	16	0	0	16
Gamma-aminobutyric acid receptor subunit pi	16	5	0	22
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	36
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	4	0	5
UDP-glucuronosyltransferase 1A9	0	1	0	4
Bile salt export pump	0	13	0	13
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Bile salt export pump	0	60	0	60
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	17	0	19
Carbonic anhydrase 2	0	17	2	21
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	3	1	5
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 3	0	4	0	5
Cytochrome P450 3A4	0	15	2	19
Cytochrome P450 2D6	0	6	1	7
Cytochrome P450 2C9	0	12	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	16	5	0	22
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	16	5	0	22
Gamma-aminobutyric acid receptor subunit gamma-2	16	5	1	23
UDP-glucuronosyltransferase 1-6	0	2	0	3
Glutamate receptor 2	28	1	0	29
Gamma-aminobutyric acid receptor subunit alpha-5	16	5	0	22
Gamma-aminobutyric acid receptor subunit alpha-3	16	5	0	22
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	6
Carbonic anhydrase 4	0	7	0	8
Prostaglandin G/H synthase 1	0	7	0	7
Carbonic anhydrase 6	0	8	0	9
Gamma-aminobutyric acid receptor subunit gamma-1	16	5	0	22
Gamma-aminobutyric acid receptor subunit alpha-2	16	5	0	22
Gamma-aminobutyric acid receptor subunit alpha-4	16	5	0	22
Gamma-aminobutyric acid receptor subunit gamma-3	16	5	0	22
Gamma-aminobutyric acid receptor subunit alpha-6	16	5	0	22
Carbonic anhydrase 5A, mitochondrial	0	5	0	7
Prostaglandin G/H synthase 2	0	10	2	13
Carbonic anhydrase 7	0	5	0	6
Nuclear receptor ROR-gamma	14	1	1	16
Cytochrome P450 2J2	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	16	5	1	23
Gamma-aminobutyric acid receptor subunit beta-3	16	5	0	22
Gamma-aminobutyric acid receptor subunit beta-2	16	5	1	23
Carbonic anhydrase 9	0	7	0	8
GABA theta subunit	16	5	0	22
Canalicular multispecific organic anion transporter 1	0	33	0	34
Carbonic anhydrase 15	0	7	0	7
Carbonic anhydrase 13	0	4	0	5
Gamma-aminobutyric acid receptor subunit epsilon	16	5	0	22
Carbonic anhydrase 14	0	4	0	5
Carbonic anhydrase 5B, mitochondrial	0	4	0	5
toxin B	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	24	0	0	24
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	22	0	0	22
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
phosphopantetheinyl transferase	17	0	0	17
TDP1 protein	41	0	0	41
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
vitamin D3 receptor isoform VDRA	16	0	0	16
thyroid hormone receptor beta isoform a	19	0	0	19
DNA polymerase kappa isoform 1	17	0	0	17
histone acetyltransferase KAT2A isoform 1	18	0	0	18
Chain A, Beta-lactamase	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	15	0	0	15
geminin	47	0	0	47
Gamma-aminobutyric acid receptor subunit rho-1	0	1	2	3
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	10	0	10
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 2	0	7	0	7
Chain A, 2-oxoglutarate Oxygenase	20	0	0	20
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	6
Beta-lactamase	0	0	0	6
AR protein	57	0	0	57
apical membrane antigen 1, AMA1	6	0	0	6
Beta-lactamase	0	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	16	0	0	16
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
Beta-lactamase SHV-1	0	0	0	5
Beta-lactamase SHV-1	0	0	0	5
Beta-lactamase	0	0	0	6
Kappa-type opioid receptor	0	2	0	7
B2 metallo-beta-lactamase	0	0	0	4
Solute carrier family 15 member 2	0	6	0	6
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	6
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	9	0	0	9
Beta-lactamase	0	2	0	6
acid sphingomyelinase	3	0	0	3
GLI family zinc finger 3	41	0	0	41
farnesoid X nuclear receptor	28	0	0	28
Beta-lactamase	0	2	0	6
Beta-lactamase	0	0	0	5
Metallo-beta-lactamase type 2	0	0	0	6
Metallo-beta-lactamase VIM-11	0	0	0	5
Metallo-beta-lactamase VIM-2	0	0	0	5
Beta-lactamase	0	0	0	6
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
DNA polymerase beta	7	0	0	7
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	3
Spike glycoprotein	21	0	1	22
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	1	3	4
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	1	0	6
Efflux transporter	0	1	0	4
Beta-lactamase	0	0	0	5
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	1	0	4
Class D beta-lactamase	0	0	0	3
60 kDa chaperonin	0	5	0	5
Metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	5	0	5
Metallo-b-lactamase	0	0	0	8
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	6
Histamine H3 receptor	0	0	0	6
Beta-lactamase class B VIM-2	0	0	0	8
Beta-lactamase VIM-1	0	1	0	6
ATP-dependent phosphofructokinase	14	0	0	14
Chain A, Putative fructose-1,6-bisphosphate aldolase	12	0	0	12
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
Luciferase	18	0	0	18
interleukin 8	10	0	0	10
endonuclease IV	6	0	0	6
BRCA1	1	0	0	1
RGS12	1	0	0	1
15-lipoxygenase, partial	9	0	0	9
hypoxia-inducible factor 1 alpha subunit	19	0	0	19
USP1 protein, partial	20	0	0	20
NFKB1 protein, partial	2	0	0	2
PPM1D protein	7	0	0	7
Thrombopoietin	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
estrogen receptor 2 (ER beta)	24	0	0	24
regulator of G-protein signaling 4	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	31	0	0	31
glucocorticoid receptor [Homo sapiens]	34	0	0	34
pregnane X nuclear receptor	35	0	0	35
G	16	0	0	16
cytochrome P450 2D6	18	0	0	18
Neuraminidase	0	2	0	2
67.9K protein	12	0	0	12
glucocerebrosidase	6	0	0	6
Parkin	5	0	0	5
peroxisome proliferator-activated receptor delta	25	0	0	25
vitamin D (1,25- dihydroxyvitamin D3) receptor	28	0	0	28
arylsulfatase A	13	0	0	13
pyruvate kinase	1	0	0	1
IDH1	15	0	0	15
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	21	0	0	21
Histone H2A.x	23	0	0	23
Replicase polyprotein 1ab	0	1	2	3
cytochrome P450 2D6 isoform 1	8	0	0	8
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
peripheral myelin protein 22 isoform 1	7	0	0	7
hemoglobin subunit beta	5	0	0	5
cellular tumor antigen p53 isoform a	13	0	0	13
cytochrome P450 2C19 precursor	5	0	0	5
cytochrome P450 2C9 precursor	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
histone deacetylase 9 isoform 3	3	0	0	3
heat shock protein beta-1	17	0	0	17
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	11	0	0	11
flap endonuclease 1	13	0	0	13
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	43	0	0	43
nuclear receptor ROR-gamma isoform 1	17	0	0	17
survival motor neuron protein isoform d	18	0	0	18
M-phase phosphoprotein 8	8	0	0	8
lamin isoform A-delta10	39	0	0	39
pyruvate kinase PKM isoform b	1	0	0	1
neuropeptide S receptor isoform A	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Polyphenol oxidase 2	0	3	0	5
Aldo-keto reductase family 1 member B10	0	3	0	3
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Lysozyme C-1	0	1	0	1
Cationic trypsin	0	1	0	1
Interferon beta	20	0	0	20
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Transthyretin	0	0	2	4
Estrogen receptor	0	3	0	3
Glucocorticoid receptor	0	8	2	16
Cellular tumor antigen p53	40	0	0	40
Amyloid-beta precursor protein	1	6	0	8
Integrin beta-3	8	0	0	8
Myeloperoxidase	0	2	0	2
Cyclin-dependent kinase 1	0	1	1	2
Beta-glucuronidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	5	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	3
ATP-dependent translocase ABCB1	0	13	2	19
Neutrophil elastase	0	2	0	2
Integrin alpha-IIb	8	0	0	8
Ornithine decarboxylase	1	0	0	2
Poly [ADP-ribose] polymerase 1	0	2	0	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	2	2	4
Replicase polyprotein 1ab	0	3	2	5
Androgen receptor	0	3	1	5
Sialidase	0	1	0	1
Serine/threonine-protein kinase pim-1	0	2	1	4
Aromatase	0	5	0	5
Angiotensin-converting enzyme	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	1	1	2
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Pyruvate kinase PKM	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Urease subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	6	0	6
G2/mitotic-specific cyclin-B	0	1	0	1
Mucin-1	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Casein kinase II subunit alpha'	0	1	1	2
Amine oxidase [flavin-containing] A	0	5	0	5
Acetylcholinesterase	0	7	0	7
Amine oxidase [flavin-containing] B	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Proteasome subunit beta type-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Substance-P receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Multidrug resistance-associated protein 1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Mu-type opioid receptor	0	11	4	17
Receptor-type tyrosine-protein kinase FLT3	0	3	1	4
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	2	0	2
Acetylcholinesterase	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Delta-type opioid receptor	0	11	2	15
Kappa-type opioid receptor	0	10	3	15
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	1	2	3
Histamine H2 receptor	15	1	0	18
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Xanthine dehydrogenase/oxidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Glycogen synthase kinase-3 alpha	0	1	1	2
Glycogen synthase kinase-3 beta	0	3	1	4
Estrogen receptor	0	0	1	1
Death-associated protein kinase 1	0	1	1	2
Mitogen-activated protein kinase 10	0	1	1	2
Beta-secretase 1	0	2	0	3
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	1	3
Urease subunit beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Lactoperoxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
MO15-related protein kinase Pfmrk	0	1	0	1
Inositol monophosphatase 1	4	0	0	4
Cyclin-dependent kinase 6	0	2	1	3
Cyclin-dependent-like kinase 5	0	1	1	2
Cyclin homolog	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Mitogen-activated protein kinase 14	0	2	1	3
Cytochrome P450 1B1	0	2	0	2
Carbonic anhydrase 3	0	4	0	4
Substance-K receptor	0	1	0	1
Reverse transcriptase/RNaseH	0	1	1	2
Integrase	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Casein kinase II subunit alpha 3	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Inositol hexakisphosphate kinase 1	16	0	0	16
Estrogen receptor beta	0	3	0	3
Enoyl-acyl-carrier protein reductase	0	1	0	1
Aurora kinase B	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
ATPase family AAA domain-containing protein 5	21	0	0	21
Ataxin-2	22	0	0	22
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Myocilin	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
Prenyltransferase homolog	0	0	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	1	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	2	1	3
Carboxylic ester hydrolase	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Estrogen receptor beta	0	0	1	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	8	0	9
Sialidase-2	0	1	0	1
cytochrome P450 2C9, partial	16	0	0	16
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Ferritin light chain	11	0	0	11
acetylcholinesterase	13	0	0	13
thioredoxin reductase	23	0	0	23
SMAD family member 2	14	0	0	14
Fumarate hydratase	10	0	0	10
SMAD family member 3	14	0	0	14
thioredoxin glutathione reductase	10	0	0	10
polyprotein	10	0	0	10
P53	1	0	0	1
thyroid stimulating hormone receptor	18	0	0	18
activating transcription factor 6	20	0	0	20
Bloom syndrome protein isoform 1	13	0	0	13
muscleblind-like protein 1 isoform 1	11	0	0	11
muscarinic acetylcholine receptor M1	9	0	0	9
Protein-arginine deiminase type-4	0	12	0	12
glp-1 receptor, partial	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	0	0	7
Rap guanine nucleotide exchange factor 3	6	0	0	6
D(2) dopamine receptor	0	4	0	4
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	8	0	8
D(3) dopamine receptor	0	7	0	7
core protein, partial	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	9	0	11
Solute carrier organic anion transporter family member 1B1	0	9	0	10
pregnane X receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
galanin receptor type 3	0	1	0	1
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
ORF73	0	0	2	2
Potassium channel subfamily K member 3	0	5	0	5
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	1	3
Potassium channel subfamily K member 9	0	1	0	1
Liver carboxylesterase 1	0	0	0	2
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase VIM-19	0	0	0	5
Beta-lactamase	0	0	0	4
Albumin	0	5	8	13
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase VIM-2	0	0	0	5
Solute carrier family 22 member 6	0	6	0	7
Solute carrier family 22 member 7	0	2	0	4
BlaVIM-1	0	0	0	4
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	6	0	8
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 8	0	3	0	4
Solute carrier family 22 member 7	0	2	0	3
Solute carrier family 22 member 8	0	4	0	7
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
WRN	2	0	0	2
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
importin subunit beta-1 isoform 1	8	0	0	8
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	8	0	0	8
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase TEM	0	2	0	4
Beta-lactamase	0	0	0	3
phosphoglycerate kinase	3	0	0	3
streptokinase A precursor	0	0	3	3
lethal factor (plasmid)	10	0	0	10
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	4	0	4
30S ribosomal protein S7	0	4	0	4
50S ribosomal protein L15	0	4	0	4
50S ribosomal protein L10	0	4	0	4
50S ribosomal protein L11	0	4	0	4
50S ribosomal protein L7/L12	0	4	0	4
50S ribosomal protein L19	0	4	0	4
50S ribosomal protein L1	0	4	0	4
50S ribosomal protein L20	0	4	0	4
50S ribosomal protein L27	0	4	0	4
50S ribosomal protein L28	0	4	0	4
50S ribosomal protein L29	0	4	0	4
50S ribosomal protein L31	0	4	0	4
50S ribosomal protein L31 type B	0	4	0	4
50S ribosomal protein L32	0	4	0	4
50S ribosomal protein L33	0	4	0	4
50S ribosomal protein L34	0	4	0	4
50S ribosomal protein L35	0	4	0	4
50S ribosomal protein L36	0	4	0	4
30S ribosomal protein S10	0	4	0	4
30S ribosomal protein S11	0	4	0	4
30S ribosomal protein S12	0	4	0	4
30S ribosomal protein S13	0	4	0	4
30S ribosomal protein S16	0	4	0	4
30S ribosomal protein S18	0	4	0	4
30S ribosomal protein S19	0	4	0	4
30S ribosomal protein S20	0	4	0	4
30S ribosomal protein S2	0	4	0	4
30S ribosomal protein S3	0	4	0	4
30S ribosomal protein S4	0	4	0	4
30S ribosomal protein S5	0	4	0	4
30S ribosomal protein S8	0	4	0	4
30S ribosomal protein S9	0	4	0	4
50S ribosomal protein L13	0	4	0	4
50S ribosomal protein L14	0	4	0	4
50S ribosomal protein L16	0	4	0	4
50S ribosomal protein L23	0	4	0	4
30S ribosomal protein S15	0	4	0	4
50S ribosomal protein L17	0	4	0	4
50S ribosomal protein L21	0	4	0	4
50S ribosomal protein L30	0	4	0	4
50S ribosomal protein L6	0	4	0	4
30S ribosomal protein S14	0	4	0	4
30S ribosomal protein S17	0	4	0	4
30S ribosomal protein S1	0	4	0	4
50S ribosomal protein L18	0	4	0	4
50S ribosomal protein L2	0	4	0	4
50S ribosomal protein L3	0	4	0	4
50S ribosomal protein L24	0	4	0	4
50S ribosomal protein L4	0	4	0	4
50S ribosomal protein L22	0	4	0	4
50S ribosomal protein L5	0	4	0	4
30S ribosomal protein S21	0	4	0	4
50S ribosomal protein L25	0	4	0	4
50S ribosomal protein L36 2	0	4	0	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase	0	3	0	3
PINK1	2	0	0	2
Caspase-7	4	0	0	4
serine-protein kinase ATM isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
prostaglandin E2 receptor EP2 subtype	0	0	0	1
caspase-3	4	0	0	4
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	2	2	12
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	2	1	3
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	4
Potassium voltage-gated channel subfamily H member 2	0	12	0	13
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	3	0	3
nonstructural protein 1	8	0	0	8
LAP4	0	0	1	1
MEP2	0	0	1	1
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
huntingtin isoform 2	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	3	0	4
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Histone deacetylase 3	0	3	0	3
Botulinum neurotoxin type A	0	2	0	2
Spike glycoprotein	0	1	1	2
Alpha-1B adrenergic receptor	0	6	1	7
Catechol O-methyltransferase	0	2	0	2
Alpha-1D adrenergic receptor	0	5	1	6
Alpha-synuclein	7	3	1	11
Alpha-1A adrenergic receptor	0	7	1	8
Histone deacetylase 4	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
TAR DNA-binding protein 43	11	0	0	11
Histone deacetylase 1	0	4	0	4
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	4	1	5
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	1
transcriptional regulator ERG isoform 3	10	0	0	10
mitogen-activated protein kinase kinase kinase kinase 2 isoform 1	0	0	1	1
eyes absent homolog 2 isoform a	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
mitogen-activated protein kinase kinase kinase 3 isoform 1	0	0	1	1
Estrogen receptor	0	0	1	1
5-hydroxytryptamine receptor 1A	0	6	1	7
Cruzipain	0	2	0	2
C-terminal-binding protein 1	1	0	0	1
Estrogen receptor beta	0	0	1	1
Solute carrier family 22 member 1	0	10	0	11
Cytochrome P450 2D1	0	2	0	2
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	5
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	4	1	7
Cytochrome P450 2D4	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	3	3
PAX8	0	0	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	5	0	0	5
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	4	0	0	4
Solute carrier family 22 member 3	0	1	0	2
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	3	0	3
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	1	0	0	1
alkaline phosphatase, intestinal	0	1	0	1
caspase 7, apoptosis-related cysteine protease	7	0	0	7
toll-like receptor 9	0	1	0	1
caspase-3	7	0	0	7
TPA: protein transporter TIM10	0	1	0	1
thyrotropin-releasing hormone receptor	3	0	0	3
lysosomal alpha-glucosidase preproprotein	4	0	0	4
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	1	0	4
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
Prostaglandin E synthase	0	2	0	2
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cholinesterase	0	5	0	5
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
60 kDa chaperonin	0	3	0	3
Microtubule-associated protein tau	0	2	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	2	0	2
Tyrosinase	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Heme oxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Caspase-7	3	0	0	3
Guanine nucleotide-binding protein G	4	0	0	4
Cholinesterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	2	1	3
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	2	1	3
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Thymidine kinase 2	0	1	0	1
Deoxycytidine kinase	0	0	1	2
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	0	0	1
AAA family ATPase	0	0	0	1
Hsf1 protein	0	0	3	3
Prostaglandin G/H synthase 1	0	4	0	5
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	4	0	5
Cytochrome c oxidase subunit 2	0	2	0	2
Fatty acid-binding protein, liver	0	4	0	4
Interleukin-8	0	2	0	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	3	1	4
UDP-glucuronosyltransferase 1A4	0	1	0	2
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	6	0	6
Prostaglandin G/H synthase 2	0	3	0	4
Prostaglandin G/H synthase 1	0	3	0	4
Carbonic anhydrase 4	0	2	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	1	0	2
D(1A) dopamine receptor	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	4	0	5
5-hydroxytryptamine receptor 7	0	4	0	4
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	5	0	5
Sodium channel protein type 9 subunit alpha	0	5	0	5
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	0	4
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	7	1	8
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2A	0	4	0	4
Alpha-2B adrenergic receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	4	0	4
Muscarinic acetylcholine receptor M3	0	2	0	2
D(1A) dopamine receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	4	1	5
Histamine H2 receptor	0	6	0	6
Alpha-1D adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 2C	0	7	0	7
5-hydroxytryptamine receptor 1B	0	4	0	4
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	0	1	2
Histamine H1 receptor	0	3	0	3
Sodium-dependent serotonin transporter	0	6	0	6
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Histamine H1 receptor	0	4	0	4
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	9	0	9
5-hydroxytryptamine receptor 6	0	5	0	5
5-hydroxytryptamine receptor 4	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	8	0	8
5-hydroxytryptamine receptor 3B	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	1	1	2
Beta-2 adrenergic receptor	0	4	0	4
Beta-1 adrenergic receptor	0	2	0	2
Sodium-dependent dopamine transporter	0	3	0	3
Thromboxane-A synthase	0	4	0	4
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 5A	0	2	0	2
Taste receptor type 2 member 38	0	0	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
Serum paraoxonase/arylesterase 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	3
Caspase-3	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	2	0	3
Glutamate receptor ionotropic, NMDA 2B	0	2	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	3
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	2	9
Glutamate receptor ionotropic, NMDA 2D	0	2	0	3
Glutamate receptor ionotropic, NMDA 3B	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
Vpr	3	0	0	3
Epidermal growth factor receptor	0	4	1	5
Thymidylate synthase	0	4	0	4
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	3	0	0	3
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Menin	0	1	1	2
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	2	2
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	3	0	3
Prostaglandin G/H synthase 2	0	3	0	4
Albumin	0	1	0	2
Albumin	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	5
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	3	0	3
Caspase-1	0	3	0	4
Adenosine receptor A2a	0	3	0	3
Aldo-keto reductase family 1 member C3	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	3	0	3
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Mu-type opioid receptor	0	5	1	6
Fatty-acid amide hydrolase 1	0	3	0	3
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	5	0	6
Phospholipase A2, major isoenzyme	0	2	0	2
Procathepsin L	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Nitric oxide synthase, inducible	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
GALC protein	4	0	0	4
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Chymotrypsinogen A	0	2	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	1	2
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	2
Substance-K receptor	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	1	4
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Retinoic acid receptor alpha	0	3	2	8
Retinoic acid receptor beta	0	3	2	8
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Spike glycoprotein	0	0	1	1
Cocaine esterase	0	2	0	2
Transmembrane protease serine 2	0	0	1	1
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	1	9
Nociceptin receptor	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
Calmodulin	0	1	1	2
Angiotensin-converting enzyme 2	0	0	1	1
Sodium-dependent serotonin transporter	0	5	0	5
UDP-glucose 6-dehydrogenase	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	2	0	2
Tumor necrosis factor	0	1	1	2
Neuraminidase	0	1	0	1
Platelet-activating factor receptor	1	0	0	1
Cystathionine gamma-lyase	0	2	0	2
Cystine/glutamate transporter	0	3	0	3
Hydroxyacid oxidase 1	0	1	0	1
large T antigen	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	1	0	0	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	3	0	3
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Androgen receptor	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Stromelysin-1	0	2	1	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	1	3
Glutamate receptor 1	1	1	0	2
Glutamate receptor 3	1	1	0	2
Glutamate receptor 4	1	1	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	3	0	3
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 5	0	1	0	1
Snake venom metalloproteinase BaP1	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	1	2
Tyrosine-protein kinase JAK1	0	1	1	2
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	2	0	3
72 kDa type IV collagenase	0	2	0	2
Catechol O-methyltransferase	0	1	0	1
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Valosin-containing protein	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	2	0	2
eukaryotic translation initiation factor 4E isoform 1	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Sigma intracellular receptor 2	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Endolysin	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase	0	2	0	2
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 13	0	2	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	2	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
melanocortin receptor 4	0	1	1	2
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase PLK4	0	1	1	2
Serine/threonine-protein kinase 25	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Aurora kinase A	0	1	1	2
Cyclin-G-associated kinase	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	1	1	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	1	3
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Platelet-derived growth factor receptor beta	0	1	0	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	1	1	2
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	1	3
Insulin-like growth factor 1 receptor	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	1	1	2
Tyrosine-protein kinase HCK	0	1	1	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	1	1	2
Mast/stem cell growth factor receptor Kit	0	1	1	2
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	1	1	2
Fibroblast growth factor receptor 1	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	1	1	2
ADP/ATP translocase 3	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Serine/threonine-protein kinase B-raf	0	3	2	5
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	1	1	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
G1/S-specific cyclin-D1	0	1	0	1
Protein kinase C eta type	0	0	1	1
Cyclin-C	0	1	1	2
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Activin receptor type-2A	0	0	1	1
Mitogen-activated protein kinase 3	0	1	1	2
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Mitogen-activated protein kinase 1	0	3	1	4
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
5-hydroxytryptamine receptor 7	0	1	0	1
Myosin-10	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	1	1	2
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	2	2	5
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Serine/threonine-protein kinase mTOR	0	2	1	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	1	1	2
Casein kinase I isoform delta	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
MAP kinase-activated protein kinase 2	0	0	1	1
Cyclin-dependent kinase 8	0	1	1	2
Elongation factor Tu, mitochondrial	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	1	1	2
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	1	1	2
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Protein delta homolog 1	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	1	1	2
Serine/threonine-protein kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	1	1	2
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	1	1	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Rab-like protein 3	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	1	1	2
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	1	1	2
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
Homeodomain-interacting protein kinase 2	0	1	1	2
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	1	1	2
Serine/threonine-protein kinase PLK3	0	1	1	2
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase PLK2	0	1	1	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RuvB-like 2	0	1	1	2
RAC-gamma serine/threonine-protein kinase	0	0	1	1
RuvB-like 1	0	1	0	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	1	1	2
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
D(2) dopamine receptor	0	0	1	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Protein argonaute-2	0	0	1	1
Chain A, Glutathione S-transferase	0	1	0	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
cGMP-gated cation channel alpha-1	0	0	1	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	4	1	6
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (377)

Protein Targets (1,775)

Anal Fistula

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (377)

Drugs Studied (217)

Protein Targets (1,775)