Page last updated: 2024-08-05 13:11:57
cyclopentapyrrole
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ChEBI ID: 38296
Members (3)
| Member | Definition | Role |
|---|---|---|
| ramipril | A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. | ramipril |
| ramiprilat | A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. | ramiprilat |
| telaprevir | An oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection. | telaprevir |
Research
Studies (2,946)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 141 (4.79) | 18.7374 |
| 1990's | 493 (16.73) | 18.2507 |
| 2000's | 864 (29.33) | 29.6817 |
| 2010's | 1,331 (45.18) | 24.3611 |
| 2020's | 117 (3.97) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 751 (22.70%) | 5.53% |
| Reviews | 364 (11.00%) | 6.00% |
| Case Studies | 223 (6.74%) | 4.05% |
| Observational | 39 (1.18%) | 0.25% |
| Other | 1,932 (58.39%) | 84.16% |