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phenylethanolamines

An ethanolamine compound having a phenyl (substituted or unsubstituted) group on the carbon bearing the hydroxy substituent.

ChEBI ID: 25990

Members (14)

MemberDefinitionRole
2-hydroxyphenethylamineThe simplest member of the class of phenylethanolamines that is 2-aminoethanol bearing a phenyl substituent at the 1-position. The parent of the phenylethanolamine class.phenylethanolamine
albuterolA member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).albuterol
bambuterolA carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline.bambuterol
bambuterol hydrochlorideThe hydrochloride salt of bambuterol. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline.bambuterol hydrochloride
ephedrineA phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively.(-)-ephedrine
formoterol fumarateA phenylethanoloamine having 4-hydroxy and 3-formamido substituents on the phenyl ring and an N-(4-methoxyphenyl)propan-2-yl substituent.N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide
L-isoprenalineAn optically active phenylethanolamine compound having an isopropyl substituent attached to the nitrogen atom.L-isoprenaline
metaproterenol5-[1-hydroxy-2-(isopropanylamino)ethyl]benzene-1,3-diol; metaproterenol
metaraminolA member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension.metaraminol
n-methylphenylethanolamineAn alkaloid that is ethanolamine having the phenyl group at the 1-position and a methyl group attached to the nitrogen. It has been isolated from Halostachys caspica.N-methylphenylethanolamine
octopamineA member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.octopamine
phenylephrineA member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.phenylephrine
pseudoephedrineA member of the class of the class of phenylethanolamines that is (1S)-2-(methylamino)-1-phenylethan-1-ol in which the pro-S hydrogen at position 2 is replaced by a methyl group.pseudoephedrine
terbutalineA member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group.terbutaline

Research

Studies (33,073)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199012,300 (37.19)18.7374
1990's7,576 (22.91)18.2507
2000's7,155 (21.63)29.6817
2010's4,886 (14.77)24.3611
2020's1,156 (3.50)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials5,939 (16.08%)5.53%
Reviews1,376 (3.73%)6.00%
Case Studies1,756 (4.76%)4.05%
Observational83 (0.22%)0.25%
Other27,772 (75.21%)84.16%