Page last updated: 2024-08-05 10:44:02
pyridine alkaloid
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ChEBI ID: 26416
Members (15)
| Member | Definition | Role |
|---|---|---|
| 3-(1-methylpyrrolidin-2-yl)pyridine | An N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2. | 3-(1-methylpyrrolidin-2-yl)pyridine |
| actinidine | A member of the class of cyclopentapyridines that is 6,7-dihydrocyclopenta[c]pyridine bearing two methyl substituents at positions 4 and 7. | actinidine |
| anabasine | A pyridine alkaloid that is pyridine substituted by a piperidin-2-yl group at position 3. | anabasine |
| arecoline | A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine. | arecoline |
| cerulomycin | A pyridine alkaloid that is 2,2'-bipyridine substituted by a methoxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity. | caerulomycin A |
| euonine | A sesquiterpene alkaloid that has been isolated from Tripterygium wilfordii and exhibits immunosuppressive and insecticidal properties. It was found to be identical with euonine, previously isolated from Euonymous sieboldiana. | wilformine |
| gentianine | gentianine | |
| guvacine | A alpha,beta-unsaturated monocarboxylic acid that is nicotinic acid which has been hydrogenated at the 1-2 and 5-6 positions of the pyridine ring. | guvacine |
| guvacoline | The methyl ester of guvacine. | guvacoline |
| myosmine | A member of the class of pyridines that is pyridine substituted by a 3,4-dihydro-2H-pyrrol-5-yl group at position 3. It is an alkaloid found in tobacco plants and exhibits genotoxic effects. | myosmine |
| niacin | A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. | nicotinic acid |
| niacinamide | A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. | nicotinamide |
| pseudooxynicotine | An aminoacylpyridine that is pyridine substituted at position 3 by a 4-(methylamino)butanoyl group. | pseudooxynicotine |
| ricinine | ricinine | |
| wilforgine | A dihydroagarofuran sesquiterpenoid and pyridine alkaloid with formula C41H47NO19 originally isolated from the roots of Tripterygium wilfordii. | wilforgine |
Research
Studies (23,477)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10,225 (43.55) | 18.7374 |
| 1990's | 2,058 (8.77) | 18.2507 |
| 2000's | 2,983 (12.71) | 29.6817 |
| 2010's | 6,825 (29.07) | 24.3611 |
| 2020's | 1,386 (5.90) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,580 (5.91%) | 5.53% |
| Reviews | 2,087 (7.81%) | 6.00% |
| Case Studies | 1,129 (4.23%) | 4.05% |
| Observational | 41 (0.15%) | 0.25% |
| Other | 21,880 (81.90%) | 84.16% |