Any metabolite produced by all living cells.
| Member | Definition | Class |
|---|
| 2'-deoxy-5'-adenosine monophosphate | A purine 2'-deoxyribonucleoside 5'-monophosphate having adenine as the nucleobase. | 2'-deoxyadenosine 5'-monophosphate |
| 3-phosphoglycerate | A monophosphoglyceric acid having the phospho group at the 3-position. It is an intermediate in metabolic pathways like glycolysis and calvin cycle. | 3-phosphoglyceric acid |
| 6-phosphogluconic acid | A gluconic acid phosphate having the phosphate group at the 6-position. It is an intermediate in the pentose phosphate pathway. | 6-phospho-D-gluconic acid |
| acetyl coenzyme a | An acyl-CoA having acetyl as its S-acetyl component. | acetyl-CoA |
| aconitic acid | The trans-isomer of aconitic acid. | trans-aconitic acid |
| aconitic acid | The cis-isomer of aconitic acid. | cis-aconitic acid |
| adenosine | A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond. | adenosine |
| adenosine diphosphate | A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase. | ADP |
| adenosine diphosphate | A nucleoside 5'-diphosphate(3-) arising from deprotonation of all three diphosphate OH groups of adenosine 5'-diphosphate (ADP); major species present at pH 7.3. | ADP(3-) |
| adenosine monophosphate | A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. | adenosine 5'-monophosphate |
| adenosine monophosphate | A nucleoside 5'-monophosphate(2-) that results from the removal of two protons from the phosphate group of adenosine 5'-monophosphate (AMP). | adenosine 5'-monophosphate(2-) |
| adenosine triphosphate | A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3. | ATP(4-) |
| alanine | An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. | alanine zwitterion; alanine |
| alanine | The L-enantiomer of alanine. | L-alanine zwitterion; L-alanine |
| alpha-ketoglutaric acid | An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. | 2-oxoglutaric acid |
| beta-alanine | A naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position. | beta-alanine zwitterion; beta-alanine |
| betaine | The amino acid betaine derived from glycine. | glycine betaine |
| betaine hydrochloride | A quaternary ammonium ion in which the substituents on nitrogen are methyl (three) and carboxymethyl. | N,N,N-trimethylglycinium |
| biotin | An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. | biotin |
| citric acid, anhydrous | A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms. | citric acid |
| cysteine | A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | cysteine zwitterion; cysteine |
| cysteine | The L-enantiomer of cysteinium. | L-cysteinium |
| fumaric acid | A butenedioic acid in which the C=C double bond has E geometry. It is an intermediate metabolite in the citric acid cycle. | fumaric acid |
| glyceraldehyde | An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing. | glyceraldehyde |
| glyceric acid | A trionic acid that consists of propionic acid substituted at positions 2 and 3 by hydroxy groups. | glyceric acid |
| glycine | The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. | glycine zwitterion; glycine |
| glycolaldehyde | The glycolaldehyde derived from ethylene glycol. The parent of the class of glycolaldehydes. | glycolaldehyde |
| guanosine | A purine nucleoside in which guanine is attached to ribofuranose via a beta-N(9)-glycosidic bond. | guanosine |
| homocysteine | An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-homocysteine; major species at pH 7.3. | L-homocysteine zwitterion; L-homocysteine |
| hypoxanthine | A purine nucleobase that consists of purine bearing an oxo substituent at position 6. | hypoxanthine |
| inosine diphosphate | A purine ribonucleoside 5'-diphosphate having inosine as the nucleobase. | IDP |
| isocitric acid | A tricarboxylic acid that is propan-1-ol with a hydrogen at each of the 3 carbon positions replaced by a carboxy group. | isocitric acid |
| malic acid | A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group. | malic acid |
| mannose 1-phosphate | A mannose phosphate that is D-mannose carrying a phosphate group at position 1. | D-mannose 1-phosphate |
| nadp | | NADP zwitterion |
| phenylpyruvic acid | A 2-oxo monocarboxylic acid that is 3-phenylpropanoic acid substituted by an oxo group at position 2. It is an intermediate metabolite in the phenylalanine pathway. | keto-phenylpyruvic acid |
| phosphoenolpyruvate | A monocarboxylic acid that is acrylic acid substituted by a phosphonooxy group at position 2. It is a metabolic intermediate in pathways like glycolysis and gluconeogenesis. | phosphoenolpyruvic acid |
| pseudouridine | A C-glycosyl pyrimidine that consists of uracil having a beta-D-ribofuranosyl residue attached at position 5. The C-glycosyl isomer of the nucleoside uridine. | pseudouridine |
| putrescine | A four-carbon alkane-alpha,omega-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh. | putrescine |
| pyruvic acid | A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis. | pyruvic acid |
| riboflavin | D-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. | riboflavin |
| s-adenosylhomocysteine | An organic sulfide that is the S-adenosyl derivative of L-homocysteine. | S-adenosyl-L-homocysteine zwitterion; S-adenosyl-L-homocysteine |
| serum p-component | A tricarboxylic acid trianion, obtained by deprotonation of the three carboxy groups of citric acid. | citrate(3-) |
| spermidine | A triamine that is the 1,5,10-triaza derivative of decane. | spermidine |
| spermine | A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism. | spermine |
| succinic acid | An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. | succinic acid |
| thioctic acid | A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position. | lipoic acid |
| thymidine monophosphate | The neutral species of thymidine 5'-monophosphate (2'-deoxythymidine 5'-monophosphate). | dTMP |
| tyrosine | An optically active form of tyrosine having L-configuration. | L-tyrosine zwitterion; L-tyrosine |
| uridine | A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond. | uridine |
| uridine diphosphate glucose | The alpha-anomer of UDP-alpha-D-glucose. It is used in nucleotide sugars metabolism. | UDP-alpha-D-glucose |
| uridine diphosphate xylose | A UDP-sugar having alpha-xylose as the sugar component. It is an important metabolite in the nucleotide sugar metabolism in animals, plants, fungi, and bacteria. | UDP-alpha-D-xylose |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 17.0716 | 1 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 41.0791 | 3 | 6 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 36.9096 | 2 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.3741 | 1 | 4 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.3162 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 25.5906 | 10 | 23 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 54.1732 | 2 | 3 |
| arylsulfatase A | Homo sapiens (human) | Potency | 4.7755 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.5844 | 3 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 21.7838 | 3 | 5 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 45.0626 | 1 | 2 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 21.7660 | 1 | 8 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 19.5582 | 1 | 4 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 36.4907 | 2 | 4 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 23.8362 | 1 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 61.9986 | 1 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 27.7134 | 2 | 11 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 16.2324 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 17.8741 | 2 | 8 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 23.8362 | 1 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 25.0046 | 2 | 4 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 23.2328 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.7081 | 2 | 5 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 51.6252 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 47.9134 | 1 | 2 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 4.6109 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.5238 | 9 | 25 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 66.4843 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 24.2397 | 3 | 5 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 11.5772 | 1 | 7 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 26.3506 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 35.3294 | 4 | 7 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 8.4368 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 7.0679 | 2 | 4 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 29.7594 | 2 | 7 |
| GLS protein | Homo sapiens (human) | Potency | 9.6985 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 24.4868 | 3 | 13 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.5012 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 7.7306 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.5012 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.5012 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 25.5668 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 12.3851 | 2 | 13 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 21.4865 | 1 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 28.5778 | 2 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 52.7082 | 1 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 18.1258 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 19.0919 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 4.1544 | 1 | 3 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 12.8720 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 22.1060 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 40.5334 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 12.1743 | 1 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 4.9019 | 2 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 28.1838 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 12.5893 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 35.5975 | 4 | 23 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 29.2858 | 1 | 2 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 46.9762 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 16.8158 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 57.6980 | 3 | 6 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 1.6137 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 43.5678 | 4 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 27.6317 | 5 | 8 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 81.0568 | 1 | 6 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 12.3238 | 1 | 5 |
| PPM1D protein | Homo sapiens (human) | Potency | 4.1544 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 25.9406 | 2 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 53.7884 | 2 | 5 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 28.0774 | 2 | 10 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 4.0933 | 1 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 47.4157 | 2 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 25.0232 | 4 | 10 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 24.7013 | 2 | 2 |
| signal transducer and activator of transcription 6, interleukin-4 induced | Homo sapiens (human) | Potency | 1.2589 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 39.8176 | 3 | 6 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 39.8176 | 3 | 6 |
| Smad3 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 11.4776 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.5939 | 2 | 6 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 16.9572 | 1 | 3 |
| Thrombopoietin | Homo sapiens (human) | Potency | 7.1264 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 17.9636 | 2 | 2 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 7.0502 | 3 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 27.7385 | 6 | 16 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 15.4331 | 2 | 5 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 53.0804 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 30.0403 | 2 | 8 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 26.4435 | 5 | 11 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 66.8968 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 14.9601 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 4.5885 | 2 | 2 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 59.0000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 3,675.0000 | 1 | 2 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 40.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | Ki | 0.0009 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 59.0000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Adenosine kinase | Toxoplasma gondii | Ki | 8.9000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 0.0023 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 0.8128 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 0.1523 | 5 | 6 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 0.2900 | 3 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 0.0240 | 3 | 3 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 0.0210 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 0.0011 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.2900 | 1 | 1 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | Ki | 0.1000 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | Ki | 1,472.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 59,693.3333 | 3 | 3 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Ki | 25,540.0000 | 4 | 4 |
| Alcohol dehydrogenase E chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Alcohol dehydrogenase S chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 0.0100 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | Ki | 25.5000 | 1 | 1 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 690.0000 | 1 | 5 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.4400 | 1 | 1 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 1,000.0000 | 1 | 2 |
| Beta-lactamase | Bacillus licheniformis | Ki | 1,345.0000 | 1 | 2 |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | IC50 | 3.9100 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 3 | 3 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| C-terminal-binding protein 2 | Homo sapiens (human) | IC50 | 208.1500 | 1 | 2 |
| Calcium dependent protein kinase | Zea mays | IC50 | 116.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 3 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 3 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 17.1000 | 1 | 2 |
| Carbonic anhydrase | Flaveria bidentis | Ki | 41.4000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 154.4667 | 2 | 3 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 33.1000 | 2 | 3 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 17.1000 | 1 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 0.9300 | 1 | 2 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 42.0000 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 56.3700 | 2 | 3 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 89.2500 | 1 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 0.0610 | 1 | 2 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 1.0300 | 1 | 2 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 1.1350 | 1 | 2 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 1.2000 | 1 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 0.9700 | 1 | 2 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 9.3233 | 2 | 3 |
| Chain A, ADENOSINE RECEPTOR A2A | Homo sapiens (human) | Ki | 0.0309 | 1 | 2 |
| Chain A, ADP-dependent glucokinase | Pyrococcus furiosus | Ki | 60.0000 | 1 | 1 |
| Chain A, Apolipoprotein M | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Chain A, Biotin carboxylase | Escherichia coli K-12 | IC50 | 10,000.0000 | 1 | 1 |
| Chain A, Biotin carboxylase | Escherichia coli K-12 | Ki | 16,000.0000 | 1 | 4 |
| Chain A, CHORISMATE MUTASE | Saccharomyces cerevisiae (brewer's yeast) | Ki | 50.0000 | 1 | 1 |
| Chain A, Cytidine Deaminase | Escherichia coli | Ki | 800.0000 | 1 | 1 |
| Chain A, Dipeptidase | Streptomyces coelicolor | Ki | 25,000.0000 | 1 | 1 |
| Chain A, EOSINOPHIL-DERIVED NEUROTOXIN | Homo sapiens (human) | Ki | 92.0000 | 1 | 3 |
| Chain A, Ermc' Methyltransferase | Bacillus subtilis | Ki | 33.0000 | 1 | 1 |
| Chain A, Ermc' Rrna Methyltransferase | Bacillus subtilis | Ki | 33.0000 | 1 | 1 |
| Chain A, Fructose-bisphosphatase | Shigella boydii | Ki | 94.0000 | 1 | 1 |
| Chain A, HEXOKINASE | Sulfurisphaera tokodaii | Ki | 18.0000 | 1 | 1 |
| Chain A, Histamine N-Methyltransferase | Homo sapiens (human) | Ki | 6.9000 | 1 | 2 |
| Chain A, Kinesin-like protein KIF11 | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| Chain A, Kinesin-like protein KIF1A, Kinesin heavy chain isoform 5C | Mus musculus (house mouse) | Ki | 350.0000 | 1 | 1 |
| Chain A, P-30 protein | Lithobates pipiens (northern leopard frog) | Ki | 590.0000 | 1 | 1 |
| Chain A, phosphodiesterase-nucleotide pyrophosphatase | Xanthomonas citri pv. citri str. 306 | Ki | 260.0000 | 1 | 1 |
| Chain A, phosphoenolpyruvate carboxykinase, cytosolic | Homo sapiens (human) | IC50 | 2.1100 | 1 | 2 |
| Chain A, Phosphoribosylformylglycinamidine synthase | Salmonella enterica subsp. enterica serovar Typhimurium | Ki | 11.0000 | 1 | 1 |
| Chain A, Proto-oncogene Tyrosine-protein Kinase Src | Homo sapiens (human) | IC50 | 40,000.0000 | 1 | 26 |
| Chain A, Purine-nucleoside Phosphorylase | Bos taurus (cattle) | Ki | 2.5000 | 1 | 1 |
| Chain A, renal dipeptidase | Streptomyces coelicolor | Ki | 25,000.0000 | 1 | 1 |
| Chain A, RIBONUCLEASE PANCREATIC | Bos taurus (cattle) | Ki | 14.3382 | 1 | 11 |
| Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN | Homo sapiens (human) | IC50 | 0.2001 | 1 | 4 |
| Chain A, Saccharopine dehydrogenase [NAD+, L-lysine-forming | Saccharomyces cerevisiae (brewer's yeast) | Ki | 55.0000 | 1 | 1 |
| Chain A, Saccharopine dehydrogenase, NAD+, L-lysine-forming | Saccharomyces cerevisiae (brewer's yeast) | Ki | 55.0000 | 1 | 1 |
| Chain A, Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | IC50 | 38.0000 | 1 | 1 |
| Chain A, Uroporphyrin-III C-methyltransferase | Pseudomonas denitrificans (nom. rej.) | Ki | 0.3200 | 1 | 1 |
| Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN | Homo sapiens (human) | IC50 | 0.2001 | 1 | 4 |
| Chain B, Succinyl-CoA:acetate coenzyme A transferase | Acetobacter aceti | Ki | 150,000.0000 | 1 | 1 |
| Choline O-acetyltransferase | Homo sapiens (human) | IC50 | 1,800,000,000.0000 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Cytidine deaminase | Homo sapiens (human) | Ki | 0.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 2.6000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 2,818.3800 | 1 | 1 |
| Delta-aminolevulinic acid dehydratase | Escherichia coli K-12 | Ki | 12,500.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | IC50 | 1.4212 | 10 | 10 |
| DNA (cytosine-5)-methyltransferase 3A | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3B | Homo sapiens (human) | IC50 | 10.2900 | 5 | 5 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 7.6700 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Egl nine homolog 1 | Homo sapiens (human) | IC50 | 3,387.8833 | 4 | 6 |
| Endoplasmin | Canis lupus familiaris (dog) | IC50 | 11.4470 | 1 | 1 |
| Endoplasmin | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 195.0000 | 1 | 1 |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | IC50 | 44.0000 | 2 | 3 |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | Ki | 31.5000 | 1 | 2 |
| Equilibrative nucleoside transporter 2 | Homo sapiens (human) | IC50 | 170.0000 | 1 | 2 |
| Equilibrative nucleoside transporter 2 | Homo sapiens (human) | Ki | 174.0000 | 1 | 2 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 16.5600 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 16.5600 | 1 | 1 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 150.0000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.6436 | 11 | 11 |
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | IC50 | 1.3000 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 51.1807 | 7 | 9 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 48.9152 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 33,597.8571 | 7 | 7 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | Ki | 2,500.0000 | 1 | 1 |
| Glycine--tRNA ligase | Bombyx mori (domestic silkworm) | Ki | 80.0000 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5880 | 1 | 1 |
| Heat shock 70 kDa protein 1A | Homo sapiens (human) | IC50 | 280.2500 | 1 | 2 |
| Heat shock protein 75 kDa, mitochondrial | Homo sapiens (human) | IC50 | 55.5940 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | IC50 | 59.3080 | 1 | 1 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Ki | 3.0000 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 42.1590 | 1 | 1 |
| hepatocyte nuclear factor 4-alpha isoform 2 | Homo sapiens (human) | IC50 | 39.8690 | 1 | 1 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.2008 | 1 | 1 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 0.3851 | 2 | 2 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 2 |
| Histamine N-methyltransferase | Homo sapiens (human) | Ki | 14.3000 | 1 | 2 |
| Histone-arginine methyltransferase CARM1 | Homo sapiens (human) | Ki | 0.6300 | 2 | 2 |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | IC50 | 1.5120 | 2 | 2 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.2300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 2.6400 | 3 | 3 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | Ki | 0.5700 | 1 | 1 |
| Histone-lysine N-methyltransferase EZH1 | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Histone-lysine N-methyltransferase EZH2 | Homo sapiens (human) | IC50 | 24.8400 | 5 | 5 |
| Histone-lysine N-methyltransferase KMT5C | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase NSD2 | Homo sapiens (human) | IC50 | 39.1000 | 1 | 1 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 38.5000 | 2 | 2 |
| Histone-lysine N-methyltransferase SETDB1 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H1 | Homo sapiens (human) | Ki | 4.9000 | 1 | 1 |
| Histone-lysine N-methyltransferase SUV39H2 | Homo sapiens (human) | IC50 | 27.0000 | 2 | 2 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 20.3120 | 5 | 5 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | Ki | 0.1967 | 3 | 3 |
| Indolethylamine N-methyltransferase | Homo sapiens (human) | Ki | 2.0000 | 1 | 2 |
| Inosine-5'-monophosphate dehydrogenase | Escherichia coli K-12 | Ki | 450.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | IC50 | 500.0000 | 2 | 2 |
| L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| L-lactate dehydrogenase B chain | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 134.0000 | 2 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 1,155.0000 | 1 | 2 |
| Lysine-specific demethylase 5B | Homo sapiens (human) | IC50 | 800.0000 | 1 | 1 |
| Methylosome protein 50 | Homo sapiens (human) | IC50 | 0.5800 | 2 | 2 |
| Monocarboxylate transporter 2 | Rattus norvegicus (Norway rat) | Ki | 80.0000 | 1 | 1 |
| N-lysine methyltransferase SMYD2 | Homo sapiens (human) | IC50 | 0.1800 | 1 | 1 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | Homo sapiens (human) | Ki | 5,000.0000 | 1 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Homo sapiens (human) | IC50 | 640.0000 | 1 | 1 |
| N6-adenosine-methyltransferase catalytic subunit | Homo sapiens (human) | IC50 | 0.5900 | 1 | 1 |
| Nicotinamide N-methyltransferase | Homo sapiens (human) | IC50 | 35.3000 | 1 | 1 |
| Non-structural protein 1 | Dengue virus | IC50 | 0.4900 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 0.2000 | 1 | 1 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Ki | 3,500.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 3.7080 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 4.5885 | 2 | 2 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 45.6500 | 1 | 2 |
| Phenylethanolamine N-methyltransferase | Homo sapiens (human) | Ki | 14.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | IC50 | 87.8000 | 1 | 2 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | Ki | 59.6500 | 1 | 2 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | IC50 | 87.8000 | 1 | 2 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Ki | 59.6500 | 1 | 2 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | IC50 | 87.8000 | 1 | 2 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | Ki | 59.6500 | 1 | 2 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | IC50 | 87.8000 | 1 | 2 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | Ki | 59.6500 | 1 | 2 |
| Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | Rattus norvegicus (Norway rat) | Ki | 289.0000 | 1 | 1 |
| Phosphoglycerate kinase 1 | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Phosphoglycerate kinase 2 | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 842.5200 | 1 | 5 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.0002 | 1 | 1 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 0.4300 | 4 | 4 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | Ki | 0.4000 | 1 | 1 |
| Protein arginine N-methyltransferase 3 | Homo sapiens (human) | IC50 | 0.9567 | 3 | 3 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 12.8400 | 4 | 4 |
| Protein arginine N-methyltransferase 7 | Homo sapiens (human) | IC50 | 25.0550 | 2 | 2 |
| Protein cereblon | Homo sapiens (human) | IC50 | 757.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | Ki | 390.0000 | 1 | 1 |
| Protein dpy-30 homolog | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 26,666.7000 | 3 | 3 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 3,050.0000 | 1 | 4 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Ki | 2,000.0000 | 1 | 1 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 1.4100 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 1,600.0000 | 1 | 1 |
| Retinoblastoma-binding protein 5 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Ki | 0.3500 | 1 | 1 |
| rRNA adenine N-6-methyltransferase | Streptococcus pneumoniae | Ki | 40.0000 | 2 | 2 |
| Sensor protein kinase WalK | Staphylococcus aureus | IC50 | 7.1890 | 1 | 1 |
| Serine racemase | Homo sapiens (human) | Ki | 366.0000 | 1 | 1 |
| Set1/Ash2 histone methyltransferase complex subunit ASH2 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | IC50 | 331.1310 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 2,779.9967 | 3 | 3 |
| Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (human) | IC50 | 154.5000 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 750.8556 | 4 | 5 |
| Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (human) | IC50 | 41.2000 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 378.7898 | 3 | 4 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 68.8000 | 2 | 2 |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | IC50 | 5.6500 | 1 | 2 |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | Ki | 3.5000 | 1 | 2 |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | IC50 | 18.7500 | 1 | 2 |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | Ki | 18.1500 | 1 | 2 |
| Solute carrier family 13 member 3 | Homo sapiens (human) | IC50 | 107.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 740.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 700.0000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 10,370.1322 | 1 | 6 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 3,626.6611 | 2 | 7 |
| Solute carrier family 28 member 3 | Homo sapiens (human) | IC50 | 4.3500 | 1 | 2 |
| Solute carrier family 28 member 3 | Homo sapiens (human) | Ki | 2.7500 | 1 | 2 |
| Solute carrier organic anion transporter family member 2A1 | Homo sapiens (human) | Ki | 19,500.0000 | 1 | 2 |
| SUMO-conjugating enzyme UBC9 | Homo sapiens (human) | IC50 | 2.6800 | 2 | 2 |
| SUMO1 activating enzyme subunit 1 | Homo sapiens (human) | IC50 | 2.6800 | 2 | 2 |
| Tat | Human immunodeficiency virus 1 | IC50 | 5.8910 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 8.8000 | 1 | 1 |
| Thymidylate kinase | Mycobacterium tuberculosis H37Rv | Ki | 4.5000 | 1 | 1 |
| Thymidylate synthase | Lacticaseibacillus casei | Ki | 12.0950 | 2 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 70.0000 | 2 | 2 |
| tRNA (cytosine(38)-C(5))-methyltransferase | Homo sapiens (human) | IC50 | 15.8000 | 1 | 1 |
| Tubulin--tyrosine ligase | Homo sapiens (human) | Ki | 25.0000 | 1 | 1 |
| Ubiquitin-like modifier activating enzyme 2 | Homo sapiens (human) | IC50 | 2.6800 | 2 | 2 |
| Vif | Human immunodeficiency virus 1 | IC50 | 7.6700 | 1 | 1 |
| WD repeat-containing protein 5 | Homo sapiens (human) | IC50 | 0.7240 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Kd | 1,786.7533 | 1 | 3 |
| 3-dehydroquinate dehydratase | Helicobacter pylori 26695 | Kd | 2.5000 | 1 | 1 |
| 3-dehydroquinate dehydratase | Streptomyces coelicolor A3(2) | Kd | 7.3000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | EC50 | 3.7095 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 3.6500 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 6-phosphogluconolactonase | Trypanosoma brucei | Kd | 10.0000 | 1 | 1 |
| Adenosine receptor A1 | Cavia porcellus (domestic guinea pig) | EC50 | 3.3884 | 2 | 2 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 0.6411 | 8 | 9 |
| Adenosine receptor A1 | Homo sapiens (human) | Kd | 0.2951 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Kd | 1.9498 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 5.4125 | 9 | 9 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | EC50 | 40.0000 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Kd | 0.0173 | 1 | 1 |
| Adenosine receptor A2b | Homo sapiens (human) | EC50 | 18.9935 | 9 | 9 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | EC50 | 40.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | EC50 | 0.3689 | 6 | 6 |
| Adenosine receptor A3 | Homo sapiens (human) | Kd | 0.7400 | 1 | 1 |
| Avidin | Gallus gallus (chicken) | Kd | 117.0000 | 1 | 1 |
| Caspase-2 | Homo sapiens (human) | EC50 | 8.5000 | 1 | 1 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | Homo sapiens (human) | Kd | 1.3000 | 1 | 2 |
| Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4 | Homo sapiens (human) | Kd | 3.3000 | 1 | 4 |
| Chain A, 6-PHOSPHOGLUCONATE DEHYDROGENASE | Ovis aries (sheep) | Kd | 2.0000 | 1 | 1 |
| Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain A, a non-biological ATP binding protein with two mutations N32D and D65V | unidentified | Kd | 0.4500 | 1 | 1 |
| Chain A, A-TYPE ATP SYNTHASE CATALYTIC SUBUNIT A | Pyrococcus horikoshii OT3 | Kd | 3.2300 | 1 | 1 |
| Chain A, abiotic ATP-binding, folding optimized protein | unidentified | Kd | 0.4940 | 1 | 1 |
| Chain A, Adenine-n6-dna-methyltransferase Taqi | Thermus aquaticus | Kd | 2.4000 | 1 | 2 |
| Chain A, Akap18 Delta | Homo sapiens (human) | Kd | 194.0000 | 1 | 1 |
| Chain A, Aspartate Aminotransferase | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, ATP Binding Protein-DX | unidentified | Kd | 0.3500 | 1 | 9 |
| Chain A, ATP synthase epsilon chain | Bacillus sp. PS3 | Kd | 1.4000 | 1 | 1 |
| Chain A, ATP-dependent RNA helicase A | Homo sapiens (human) | Kd | 18.0000 | 1 | 1 |
| Chain A, Avidin | Gallus gallus (chicken) | Kd | 0.3000 | 1 | 2 |
| Chain A, Betaine ABC transporter permease and substrate binding protein | Lactococcus lactis | Kd | 4.0000 | 1 | 1 |
| Chain A, Biotin [acetyl-CoA-carboxylase] ligase | Aquifex aeolicus | Kd | 4.6000 | 1 | 2 |
| Chain A, Capsid protein | Norwalk virus | Kd | 460.0000 | 1 | 1 |
| Chain A, Chloride Channel Protein 5 | Homo sapiens (human) | Kd | 100.0000 | 1 | 4 |
| Chain A, Chromosomal replication initiator protein dnaA | Thermotoga maritima | Kd | 0.0240 | 1 | 1 |
| Chain A, Competence Protein Pilm | Thermus thermophilus HB27 | Kd | 1,000.0000 | 1 | 1 |
| Chain A, Copper-transporting ATPase 1 | Homo sapiens (human) | Kd | 83.3000 | 1 | 1 |
| Chain A, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain A, Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 51.3000 | 1 | 1 |
| Chain A, D-alanine-poly(phosphoribitol) ligase | Bacillus cereus | Kd | 1,100.0000 | 1 | 1 |
| Chain A, Dethiobiotin synthetase | Helicobacter pylori 26695 | Kd | 4.4333 | 1 | 9 |
| Chain A, Diacylglycerol Kinase DgkB | Staphylococcus aureus | Kd | 219.0000 | 1 | 1 |
| Chain A, DODECIN | Halobacterium salinarum R1 | Kd | 1.2680 | 1 | 2 |
| Chain A, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain A, Endoplasmin | Canis lupus familiaris (dog) | Kd | 5.0000 | 1 | 1 |
| Chain A, Excinuclease ABC subunit A | Geobacillus stearothermophilus 10 | Kd | 0.0100 | 1 | 1 |
| Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE | Bacillus subtilis | Kd | 11.0000 | 1 | 1 |
| Chain A, Glycine betaine-binding periplasmic protein | Escherichia coli | Kd | 4.0000 | 1 | 1 |
| Chain A, Glycine betaine-binding protein | Bacillus subtilis | Kd | 17.0000 | 1 | 2 |
| Chain A, Glycine betaine/carnitine/choline-binding protein | Bacillus subtilis | Kd | 6.0000 | 1 | 4 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 101.8000 | 1 | 5 |
| Chain A, Heat shock 70 kDa protein 1A/1B | Homo sapiens (human) | Kd | 1.5399 | 1 | 9 |
| Chain A, Heat Shock Protein 90 | Saccharomyces cerevisiae (brewer's yeast) | Kd | 29.0000 | 1 | 1 |
| Chain A, Heat shock protein homolog SSE1 | Saccharomyces cerevisiae (brewer's yeast) | Kd | 0.2000 | 1 | 1 |
| Chain A, Malonyl CoA synthetase | Rhodopseudomonas palustris CGA009 | Kd | 0.3100 | 1 | 1 |
| Chain A, Membrane lipoprotein tmpC | Treponema pallidum | Kd | 0.1705 | 1 | 6 |
| Chain A, Modification Methylase Rsri | Cereibacter sphaeroides | Kd | 8.1000 | 1 | 2 |
| Chain A, Myosin Ie Heavy Chain | Dictyostelium discoideum | Kd | 7.1000 | 1 | 1 |
| Chain A, N5-carboxyaminoimidazole ribonucleotide mutase | Acetobacter aceti | Kd | 1,200.0000 | 1 | 4 |
| Chain A, NAD(P) transhydrogenase subunit alpha part 1 | Rhodospirillum rubrum | Kd | 700.0000 | 1 | 3 |
| Chain A, Nitrogen regulatory protein P-II | Mycobacterium tuberculosis | Kd | 1.9300 | 1 | 1 |
| Chain A, NITROGEN REGULATORY PROTEIN P-II | Synechococcus elongatus PCC 7942 = FACHB-805 | Kd | 9.6000 | 1 | 1 |
| Chain A, Nitrogen regulatory protein P-II (GlnB-2) | Archaeoglobus fulgidus | Kd | 40.9500 | 1 | 4 |
| Chain A, Ntpase P4 | Pseudomonas phage phi12 | Kd | 132.5000 | 1 | 4 |
| Chain A, nucleoside diphosphate kinase A | Homo sapiens (human) | Kd | 6.0000 | 1 | 1 |
| Chain A, Osmoprotection protein (ProX) | Archaeoglobus fulgidus | Kd | 76.0000 | 1 | 1 |
| Chain A, osmoprotection protein (proX) | Archaeoglobus fulgidus DSM 4304 | Kd | 0.0600 | 1 | 2 |
| Chain A, Preprotein translocase secA | Bacillus subtilis | Kd | 0.1000 | 1 | 1 |
| Chain A, Preprotein translocase subunit secA | Escherichia coli | Kd | 0.1900 | 1 | 1 |
| Chain A, Probable copper-exporting P-type ATPase A | Archaeoglobus fulgidus | Kd | 75.0000 | 1 | 3 |
| Chain A, Protein (aspartate Aminotransferase) | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain A, Protein argonaute 1 | Arabidopsis thaliana (thale cress) | Kd | 4,990.0000 | 1 | 4 |
| Chain A, Protein argonaute-2 | Homo sapiens (human) | Kd | 90.0000 | 1 | 2 |
| Chain A, protein Bug27 | Bordetella pertussis | Kd | 0.4300 | 1 | 1 |
| Chain A, Protein hipA | Escherichia coli | Kd | 18.0000 | 1 | 2 |
| Chain A, PUTRESCINE-BINDING PROTEIN | Escherichia coli | Kd | 2.0000 | 1 | 1 |
| Chain A, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | Bacillus subtilis | Kd | 70.0000 | 1 | 1 |
| Chain A, Rhodopsin kinase | Bos taurus (cattle) | Kd | 0.8800 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase | Pisum sativum (garden pea) | Kd | 21.2000 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase | Pisum sativum (garden pea) | Kd | 21.2000 | 1 | 3 |
| Chain A, Serine/threonine-protein kinase/endoribonuclease IRE1 | Saccharomyces cerevisiae (brewer's yeast) | Kd | 20.4000 | 1 | 1 |
| Chain A, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 13 |
| Chain A, Streptavidin Complex With Biotin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Chain A, Structure of PAE2307 in complex with adenosine | Pyrobaculum aerophilum str. IM2 | Kd | 15.0000 | 1 | 1 |
| Chain A, Thymidylate Synthase | Escherichia coli | Kd | 3.2700 | 1 | 1 |
| Chain A, Transitional endoplasmic reticulum ATPase | Mus musculus (house mouse) | Kd | 0.2300 | 1 | 1 |
| Chain A, tRNA (guanine-N(1)-)-methyltransferase | Haemophilus influenzae Rd KW20 | Kd | 641.0000 | 1 | 2 |
| Chain A, Type III pantothenate kinase | Thermotoga maritima | Kd | 3,000.0000 | 1 | 2 |
| Chain A, Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 1.0000 | 1 | 4 |
| Chain A, TYROSYL-tRNA SYNTHETASE | Geobacillus stearothermophilus | Kd | 11.6000 | 1 | 1 |
| Chain A, Uncharacterized ABC transporter ATP-binding protein MJ0796 | Methanocaldococcus jannaschii DSM 2661 | Kd | 4.2000 | 1 | 1 |
| Chain A, Uncharacterized protein MJ0883 | Methanocaldococcus jannaschii | Kd | 641.0000 | 1 | 2 |
| Chain A, V-type ATP synthase beta chain | Methanosarcina mazei | Kd | 28.0000 | 1 | 1 |
| Chain A, YuaA protein | Bacillus subtilis | Kd | 0.0200 | 1 | 9 |
| Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase | Schizosaccharomyces pombe (fission yeast) | Kd | 1.2000 | 1 | 1 |
| Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | Thermus aquaticus | Kd | 2.4000 | 1 | 1 |
| Chain B, ATP synthase epsilon chain | Bacillus sp. PS3 | Kd | 1.4000 | 1 | 1 |
| Chain B, Capsid protein | Norwalk virus | Kd | 460.0000 | 1 | 1 |
| Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE | Bacillus subtilis | Kd | 11.0000 | 1 | 1 |
| Chain B, Glycogen Phosphorylase B | Oryctolagus cuniculus (rabbit) | Kd | 85.3333 | 1 | 3 |
| Chain B, Heat shock cognate | Bos taurus (cattle) | Kd | 0.2000 | 1 | 1 |
| Chain B, N5-carboxyaminoimidazole ribonucleotide mutase | Acetobacter aceti | Kd | 1,200.0000 | 1 | 4 |
| Chain B, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1 | Mus musculus (house mouse) | Kd | 37.0000 | 1 | 1 |
| Chain B, Nitrogen regulatory protein P-II | Mycobacterium tuberculosis | Kd | 1.9300 | 1 | 1 |
| Chain B, Nitrogen regulatory protein P-II (GlnB-2) | Archaeoglobus fulgidus | Kd | 40.9500 | 1 | 4 |
| Chain B, nucleoside diphosphate kinase A | Homo sapiens (human) | Kd | 6.0000 | 1 | 1 |
| Chain B, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain B, REDOX-SENSING TRANSCRIPTIONAL REPRESSOR REX | Bacillus subtilis | Kd | 70.0000 | 1 | 1 |
| Chain B, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 4 |
| Chain B, Structure of PAE2307 in complex with adenosine | Pyrobaculum aerophilum str. IM2 | Kd | 15.0000 | 1 | 1 |
| Chain B, Type III pantothenate kinase | Thermotoga maritima | Kd | 3,000.0000 | 1 | 1 |
| Chain B, Uncharacterized ABC transporter ATP-binding protein MJ0796 | Methanocaldococcus jannaschii DSM 2661 | Kd | 4.2000 | 1 | 1 |
| Chain B, V-type ATP synthase beta chain | Methanosarcina mazei | Kd | 28.0000 | 1 | 1 |
| Chain B, YuaA protein | Bacillus subtilis | Kd | 0.0200 | 1 | 6 |
| Chain C, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain C, Ntpase P4 | Pseudomonas phage phi12 | Kd | 132.5000 | 1 | 4 |
| Chain C, Nuclear protein SNF4 | Saccharomyces cerevisiae S288C | Kd | 63.5000 | 1 | 6 |
| Chain C, Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Kd | 4.6000 | 1 | 1 |
| Chain D, Circularly Permuted Core-streptavidin E51/a46 | Streptomyces avidinii | Kd | 0.0439 | 1 | 1 |
| Chain D, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain D, DNA polymerase III subunit gamma | Escherichia coli | Kd | 3.0000 | 1 | 2 |
| Chain D, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 9 |
| Chain E, 5'-amp-activated Protein Kinase Subunit Gamma-1 | Rattus norvegicus (Norway rat) | Kd | 1.5000 | 1 | 4 |
| Chain E, DODECIN | Halorhodospira halophila | Kd | 1.2680 | 1 | 2 |
| Chain H, Immunoglobulin Igg1 Heavy chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| Chain L, Immunoglobulin Igg1 Lambda Light Chain | Homo sapiens (human) | Kd | 0.0018 | 1 | 1 |
| Chain X, MYOSIN-2 HEAVY CHAIN | Dictyostelium discoideum | Kd | 1.3000 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 11.0000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | Kd | 40.9600 | 8 | 10 |
| Endoplasmic reticulum chaperone BiP | Homo sapiens (human) | Kd | 3.0000 | 2 | 2 |
| Endoplasmin | Canis lupus familiaris (dog) | EC50 | 21.0000 | 1 | 1 |
| Endoplasmin | Homo sapiens (human) | Kd | 50.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 14.5427 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 0.4193 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | EC50 | 126.0000 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | EC50 | 36.3016 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | EC50 | 0.1593 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | EC50 | 0.1197 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | EC50 | 0.1340 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | EC50 | 0.1340 | 2 | 2 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 94.7496 | 1 | 2 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 300.0000 | 1 | 2 |
| Heat shock 70 kDa protein 1A | Homo sapiens (human) | Kd | 0.5000 | 1 | 1 |
| Heat shock cognate 71 kDa protein | Bos taurus (cattle) | Kd | 0.1100 | 1 | 1 |
| Heat shock cognate 71 kDa protein | Homo sapiens (human) | Kd | 44.6211 | 2 | 5 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | EC50 | 103.5000 | 2 | 2 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Kd | 50.0000 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | EC50 | 87.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | Kd | 0.2550 | 2 | 2 |
| HPr kinase/phosphorylase | Bacillus subtilis subsp. subtilis str. 168 | EC50 | 4,300.0000 | 1 | 1 |
| insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 2.4495 | 2 | 2 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 11.0000 | 1 | 1 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | Kd | 650.0000 | 2 | 2 |
| L-lactate dehydrogenase A chain | Rattus norvegicus (Norway rat) | Kd | 650.0000 | 1 | 1 |
| Methyl-accepting chemotaxis protein NahY | Pseudomonas putida | Kd | 110.7000 | 1 | 5 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 99.2500 | 2 | 6 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 11.0000 | 1 | 1 |
| N-alpha-acetyltransferase 50 | Homo sapiens (human) | Kd | 0.0176 | 1 | 1 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 0.2735 | 1 | 2 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0318 | 1 | 2 |
| P2X purinoceptor 1 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| P2X purinoceptor 1 | Rattus norvegicus (Norway rat) | EC50 | 10.0000 | 1 | 1 |
| P2X purinoceptor 2 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| P2X purinoceptor 3 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| P2X purinoceptor 4 | Rattus norvegicus (Norway rat) | EC50 | 28.0000 | 1 | 1 |
| P2X purinoceptor 5 | Rattus norvegicus (Norway rat) | EC50 | 18.0000 | 1 | 1 |
| P2X purinoceptor 6 | Rattus norvegicus (Norway rat) | EC50 | 11.0000 | 1 | 1 |
| P2Y purinoceptor 1 | Homo sapiens (human) | EC50 | 1.7524 | 4 | 5 |
| P2Y purinoceptor 1 | Meleagris gallopavo (turkey) | EC50 | 3.6000 | 3 | 4 |
| P2Y purinoceptor 11 | Homo sapiens (human) | EC50 | 6.8833 | 3 | 3 |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | EC50 | 0.0690 | 1 | 1 |
| P2Y purinoceptor 14 | Homo sapiens (human) | EC50 | 80.2730 | 5 | 5 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 28.4462 | 3 | 4 |
| P2Y purinoceptor 6 | Homo sapiens (human) | EC50 | 33.3000 | 2 | 2 |
| Protease | Human immunodeficiency virus 1 | Kd | 0.0011 | 1 | 1 |
| Purine nucleoside phosphorylase | Bos taurus (cattle) | Kd | 0.9650 | 2 | 2 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Kd | 0.0229 | 4 | 4 |
| Streptavidin | Streptomyces avidinii | Kd | 84.0000 | 2 | 2 |
| tRNA (cytosine(38)-C(5))-methyltransferase | Homo sapiens (human) | Kd | 13.6000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Mycobacterium tuberculosis H37Rv | Kd | 10.1000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Pseudomonas aeruginosa PAO1 | Kd | 5.9000 | 1 | 1 |
| tRNA (guanine-N(1)-)-methyltransferase | Staphylococcus aureus subsp. aureus NCTC 8325 | Kd | 3.3000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 150.0000 | 1 | 1 |
| 5-methylthioadenosine/S-adenosylhomocysteine deaminase | Thermotoga maritima MSB8 | Km | 230.0000 | 1 | 2 |
| 5'-nucleotidase | Homo sapiens (human) | Km | 14.0000 | 1 | 1 |
| Adenosine deaminase | Homo sapiens (human) | Km | 5.0000 | 1 | 1 |
| Adenosine deaminase | Mus musculus (house mouse) | Km | 7.8000 | 1 | 1 |
| Adenosine deaminase | Rattus norvegicus (Norway rat) | Km | 1,300.0000 | 1 | 1 |
| Adenosine deaminase | Bos taurus (cattle) | Km | 32.3783 | 12 | 12 |
| Adenosine deaminase-like protein | Homo sapiens (human) | Km | 32.8000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | ED50 | 10.0000 | 1 | 1 |
| Adenosine kinase | Toxoplasma gondii | Km | 2.4000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Affinity constant | 10.0050 | 2 | 2 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 0.0110 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Affinity constant | 15.0000 | 2 | 2 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 0.0110 | 1 | 2 |
| Adenosine receptor A2b | Homo sapiens (human) | Affinity constant | 15.0000 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Affinity constant | 20.0000 | 1 | 1 |
| Adenosine transporter 1 | Trypanosoma brucei | Km | 0.7000 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | Km | 422.4100 | 1 | 2 |
| Adenosylhomocysteinase | Rattus norvegicus (Norway rat) | Km | 9.7000 | 1 | 1 |
| Adenosylhomocysteinase | Thermotoga maritima MSB8 | Km | 21.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Km | 295.0000 | 1 | 2 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Adenylate kinase isoenzyme 1 | Homo sapiens (human) | Km | 837.5000 | 1 | 2 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Km | 580.0000 | 1 | 1 |
| Alanine racemase, biosynthetic | Escherichia coli K-12 | Km | 7,750.0000 | 2 | 2 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | Km | 50.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | Kcat | 41,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | Km | 6,125.0000 | 4 | 4 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Km | 441.0000 | 1 | 1 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Km | 110.0000 | 1 | 2 |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | Km | 150.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 46.1000 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 24.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 10.5000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 85.0000 | 2 | 2 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 29.5000 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 9.5000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 4.5183 | 12 | 12 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Kinact | 395.0000 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 25.8000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 21.8000 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 8.9000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | KA | 10.7245 | 14 | 14 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Kinact | 10.5000 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | KA | 34.1000 | 2 | 2 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 66.0000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ka | 25.1000 | 2 | 2 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 2.4500 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Kinact | 0.0970 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 0.0440 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Kinact | 0.0900 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ka | 9.3100 | 2 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 20.3000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 25.3000 | 1 | 1 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 4.9200 | 1 | 1 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | Kis | 36.3000 | 1 | 1 |
| Cell death-related nuclease 4 | Caenorhabditis elegans | INH | 1,000.0000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | Km | 2.0000 | 1 | 1 |
| Endoplasmin | Homo sapiens (human) | Activity | 2.3000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 20.3000 | 1 | 1 |
| GTP:AMP phosphotransferase AK3, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | Activity | 46.0000 | 2 | 2 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | Activity | 37.5000 | 2 | 2 |
| Histamine N-methyltransferase | Cavia porcellus (domestic guinea pig) | Kis | 18.1000 | 1 | 1 |
| Hypoxanthine-guanine phosphoribosyltransferase | Homo sapiens (human) | Km | 3.2500 | 2 | 2 |
| Hypoxia-inducible factor 1-alpha inhibitor | Homo sapiens (human) | Km | 25.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Monocarboxylate transporter 1 | Rattus norvegicus (Norway rat) | Km | 1,755.0000 | 2 | 2 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 2,590.0000 | 1 | 1 |
| Monocarboxylate transporter 2 | Homo sapiens (human) | Km | 25.0000 | 1 | 1 |
| Monocarboxylate transporter 4 | Homo sapiens (human) | Km | 153,000.0000 | 1 | 1 |
| NADP-dependent malic enzyme, mitochondrial | Homo sapiens (human) | Activity | 1,530.0000 | 1 | 2 |
| Phosphatidylinositol 4-kinase alpha | Homo sapiens (human) | Km | 178.9000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Km | 178.9000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-alpha | Homo sapiens (human) | Km | 178.9000 | 1 | 1 |
| Phosphatidylinositol 4-kinase type 2-beta | Homo sapiens (human) | Km | 178.9000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 0.0440 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Concentration | 50.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 230.0000 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Km | 4.5000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Homo sapiens (human) | Km | 20.0000 | 1 | 1 |
| Prolyl hydroxylase EGLN2 | Homo sapiens (human) | Km | 60.0000 | 1 | 1 |
| Prolyl hydroxylase EGLN3 | Homo sapiens (human) | Km | 55.0000 | 1 | 1 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Km | 83.0000 | 1 | 1 |
| Purine nucleoside phosphorylase | Bos taurus (cattle) | Kieq | 2.5000 | 1 | 1 |
| Pyruvate kinase PKLR | Rattus norvegicus (Norway rat) | Km | 400.0000 | 2 | 2 |
| Pyruvate kinase PKM | Rattus norvegicus (Norway rat) | Km | 520.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase beta | Homo sapiens (human) | Kis | 2,330.0000 | 1 | 1 |
| Ribonuclease T | Escherichia coli K-12 | INH | 1,000.0000 | 1 | 1 |
| S-adenosylmethionine decarboxylase proenzyme | Homo sapiens (human) | Ka | 16.0000 | 1 | 1 |
| SLC16A10 protein | Homo sapiens (human) | Km | 636.3000 | 1 | 1 |
| Solute carrier family 22 member 7 | Rattus norvegicus (Norway rat) | Km | 17.8000 | 1 | 1 |
| Squalene synthase | Homo sapiens (human) | Km | 430.0000 | 1 | 1 |
| Sulfate anion transporter 1 | Mus musculus (house mouse) | Km | 151.0000 | 1 | 1 |
| Taste receptor type 2 member 14 | Homo sapiens (human) | Activity | 1,000.0000 | 1 | 1 |
| Thymidine kinase, cytosolic | Homo sapiens (human) | Km | 5.0000 | 1 | 1 |
| Thymidylate kinase | Homo sapiens (human) | Km | 11.1000 | 3 | 3 |
| Thymidylate kinase | Mycobacterium tuberculosis H37Rv | Km | 9.5714 | 7 | 7 |
| Uridine-cytidine kinase 1 | Homo sapiens (human) | Km | 407.0000 | 1 | 1 |