A substance used to destroy fungal pests.
| Member | Definition | Class |
|---|
| 2,4,6-tribromophenol | A bromophenol that is phenol in which the hydrogens at positions 2, 4 and 6 have been replaced by bromines. It is commonly used as a fungicide and in the preparation of flame retardants. | 2,4,6-tribromophenol |
| 4,6-dinitro-o-cresol | A hydroxytoluene that is o-cresol carrying nitro substituents at positions 4 and 6. | 4,6-dinitro-o-cresol |
| allyl alcohol | A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds. | allyl alcohol |
| alpha-cadinol | A cadinane sesquiterpenoid that is cadin-4-ene carrying a hydroxy substituent at position 10. | alpha-cadinol |
| bafilomycin a1 | The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | bafilomycin A1 |
| dehydroacetic acid | A pyran-2,4-dione substituted at position 3 by an acetyl group and at position 6 by a methyl group. A fungicide and bactericide it is used primarily in processed fruit and vegetables. | dehydroacetic acid |
| disulfiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. | disulfiram |
| ethylmercuric chloride | A highly toxic organomercury compound which is used as a fungicide for treating seeds. | ethylmercuric chloride |
| kathon 930 | A 1,2-thiazole that is 1,2-thiazol-3(2H)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide. | 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone |
| methylene bis(thiocyanate) | A member of the class of thiocyanates that is methane in which two of the hycrogens have been replaced by thiocyanato groups. Used as a biocide for the control of various pathogens and algae in industrial water systems and as a fungicide for the control of surface moulds and sapstain fungi on wood. | methylene bis(thiocyanate) |
| t-muurolol | A cadinane sesquiterpenoid that consists of 4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene having a hydroxy substituent at position 1 and (1S,4S,4aR,8aS)-configuration. | (-)-Tau-muurolol |
| triclosan | An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. | triclosan |
| tropolone | A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii. | tropolone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 4.2698 | 1 | 7 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.3208 | 1 | 3 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 60.6700 | 4 | 19 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 39.2471 | 2 | 14 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 1.7401 | 1 | 7 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 8.1968 | 1 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 5.1735 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 14.1254 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 23.1577 | 11 | 84 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 40.9055 | 3 | 12 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 17.0343 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 20.5851 | 2 | 9 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 12.3044 | 2 | 2 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 24.6297 | 2 | 15 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 2.3934 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 5.2119 | 1 | 1 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 0.6513 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 23.6743 | 1 | 6 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 27.8937 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 23.6743 | 1 | 6 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 27.8937 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 27.1508 | 3 | 23 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 28.2941 | 2 | 3 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 65.8114 | 2 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 11.6698 | 2 | 7 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 32.0272 | 2 | 3 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 16.2284 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 20.3025 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 18.8231 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 55.5278 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 16.2284 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 22.9833 | 2 | 2 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 0.5380 | 2 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 2.9031 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 1.4550 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 9.0081 | 1 | 5 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 11.0068 | 1 | 3 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 11.8961 | 2 | 8 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 25.3715 | 1 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 21.6970 | 1 | 11 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 3.2641 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 76.1104 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 33.1480 | 12 | 89 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 27.9604 | 3 | 22 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 28.7950 | 10 | 88 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 1.7588 | 1 | 4 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 0.0389 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 25.4408 | 5 | 22 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 2 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 28.2089 | 1 | 5 |
| G | Vesicular stomatitis virus | Potency | 9.0081 | 1 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 11.8961 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 14.2336 | 4 | 11 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 17.9009 | 3 | 29 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 24.1654 | 2 | 6 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 32.0357 | 5 | 21 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 23.4932 | 1 | 11 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 22.3867 | 2 | 20 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 5.7014 | 2 | 14 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 22.0164 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 26.2365 | 2 | 10 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 21.8985 | 2 | 14 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 9.0081 | 1 | 5 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 9.9429 | 2 | 4 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 18.9905 | 2 | 15 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 11.5612 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 9.0081 | 1 | 10 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 15.4232 | 3 | 9 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.6594 | 2 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 6.9906 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 19.2389 | 3 | 8 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 5.5114 | 2 | 9 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 19.7830 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 7.0795 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 3.3117 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 28.2642 | 4 | 34 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 32.6427 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 42.2395 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 21.4058 | 2 | 11 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 41.9631 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 2.0926 | 2 | 14 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 25.7578 | 3 | 28 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 14.8239 | 2 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 11.9955 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 29.2943 | 5 | 29 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 29.3329 | 5 | 27 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 3.1305 | 1 | 4 |
| PINK1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| polyprotein | Zika virus | Potency | 28.2089 | 1 | 5 |
| polypyrimidine tract-binding protein 1 isoform a | Homo sapiens (human) | Potency | 14.5500 | 2 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 2.9019 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 8.8861 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 17.2206 | 1 | 2 |
| PPM1D protein | Homo sapiens (human) | Potency | 14.7403 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 40.5924 | 2 | 16 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 40.2094 | 1 | 4 |
| progesterone receptor | Homo sapiens (human) | Potency | 28.6412 | 2 | 12 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 25.1189 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 19.1368 | 2 | 27 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 1.0621 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 25.2283 | 3 | 34 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 16.0336 | 4 | 22 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 0.5380 | 2 | 2 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 0.7360 | 3 | 3 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 0.8437 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 39.3583 | 2 | 9 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 39.3583 | 2 | 9 |
| Smad3 | Homo sapiens (human) | Potency | 8.9414 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 5.3972 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 17.3506 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.0681 | 2 | 18 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 18.8926 | 2 | 3 |
| Thrombopoietin | Homo sapiens (human) | Potency | 0.3981 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 20.5243 | 3 | 29 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 39.5005 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 38.4299 | 6 | 25 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 24.0580 | 2 | 10 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 32.8363 | 2 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 13.9771 | 2 | 19 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 23.9354 | 5 | 24 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 5.1633 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 23.4932 | 1 | 11 |
| Vpr | Human immunodeficiency virus 1 | Potency | 34.4117 | 1 | 2 |