Page last updated: 2024-08-05 14:47:59

disinfectant

An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.

ChEBI ID: 48219

Members (18)

MemberDefinitionClass
1,2-benzisothiazoline-3-oneAn organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion.benzo[d]isothiazol-3-one
2,4-dimethylphenolA member of the class of phenols that phenol substituted by methyl groups at positions 2 and 4.2,4-xylenol
benzethonium chlorideA (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses.benzethonium chloride
carbamide peroxideA mixture obtained by combining equimolar amounts of hydrogen peroxide and urea.urea hydrogen peroxide
chloramine-tAn organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.chloramine T
chlorocresolA hydroxytoluene that is 3-methylphenol which is substituted by a chlorine at position 4. A ryanodine receptor agonist.4-chloro-m-cresol
chloroxylenolA member of the class of phenols that is 3,5-xylenol which is substituted at position 4 by chlorine. It is bactericidal against most Gram-positive bacteria but less effective against Staphylococci and Gram-negative bacteria, and often inactive against Pseudomonas species. It is ineffective against bacterial spores.4-chloro-3,5-dimethylphenol
dimethyldodecylbenzylammoniumThe organic bromide salt of benzododecinium. It is a cationic surfactant that has antispetic and disinfectant properties.benzododecinium bromide
formaldehydeAn aldehyde resulting from the formal oxidation of methanol.formaldehyde
glutaralA dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.glutaraldehyde
guaiacolA monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.guaiacol
ozoneAn elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.ozone
peracetic acidA peroxy acid that is acetic acid in which the OH group is substituted by a hydroperoxy group. It is a versatile oxidising agent that is used as a disinfectant.peracetic acid
phenolAn organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.phenol
sodium hypochloriteAn inorganic sodium salt in which hypochlorite is the counterion. It is used as a bleaching and disinfecting agent and is commonly found in household bleach.sodium hypochlorite
thimerosalAn alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.thimerosal
triclocarbanA member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.triclocarban
zinc chlorideA compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.zinc dichloride

Research

Studies (60,715)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199015,313 (25.22)18.7374
1990's8,170 (13.46)18.2507
2000's13,894 (22.88)29.6817
2010's16,739 (27.57)24.3611
2020's6,599 (10.87)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1,808 (2.72%)5.53%
Reviews2,914 (4.38%)6.00%
Case Studies1,467 (2.20%)4.05%
Observational60 (0.09%)0.25%
Other60,294 (90.61%)84.16%

Protein Targets (274)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency0.281811
15-lipoxygenase, partialHomo sapiens (human)Potency20.534812
67.9K proteinVaccinia virusPotency13.8901211
acetylcholinesteraseHomo sapiens (human)Potency20.6351311
acid sphingomyelinaseHomo sapiens (human)Potency112.202011
activating transcription factor 6Homo sapiens (human)Potency33.0858216
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency17.658914
alpha-galactosidaseHomo sapiens (human)Potency10.000011
Alpha-synucleinHomo sapiens (human)Potency6.181514
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency14.125411
AR proteinHomo sapiens (human)Potency23.70891084
aryl hydrocarbon receptorHomo sapiens (human)Potency17.0659311
ATAD5 protein, partialHomo sapiens (human)Potency12.054824
Ataxin-2Homo sapiens (human)Potency20.276718
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency20.330744
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency18.9698213
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency50.118711
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency33.491512
caspase-3Homo sapiens (human)Potency33.491512
Cellular tumor antigen p53Homo sapiens (human)Potency28.1282331
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency2.982225
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency28.183811
Chain A, Beta-lactamaseEscherichia coli K-12Potency16.903622
Chain A, CruzipainTrypanosoma cruziPotency22.387211
Chain A, Ferritin light chainEquus caballus (horse)Potency27.342313
Chain A, HADH2 proteinHomo sapiens (human)Potency1.000011
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency24.702812
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency5.011911
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency14.727413
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency28.573013
Chain B, HADH2 proteinHomo sapiens (human)Potency1.000011
chromobox protein homolog 1Homo sapiens (human)Potency21.679412
cytochrome P450 2C9, partialHomo sapiens (human)Potency15.314817
cytochrome P450 2D6Homo sapiens (human)Potency14.618514
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency22.697326
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency29.044127
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency23.4160111
DNA polymerase eta isoform 1Homo sapiens (human)Potency89.125111
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency43.364313
DNA polymerase kappa isoform 1Homo sapiens (human)Potency100.000011
enteropeptidase precursorHomo sapiens (human)Potency28.183811
estrogen nuclear receptor alphaHomo sapiens (human)Potency25.783512103
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency26.8296313
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency14.0470653
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency12.763613
farnesoid X nuclear receptorHomo sapiens (human)Potency29.0557525
flap endonuclease 1Homo sapiens (human)Potency55.756212
Fumarate hydrataseHomo sapiens (human)Potency27.850613
GVesicular stomatitis virusPotency15.314817
GABA theta subunitRattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency22.697313
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency22.697313
gemininHomo sapiens (human)Potency6.1233213
GLI family zinc finger 3Homo sapiens (human)Potency10.6719226
glp-1 receptor, partialHomo sapiens (human)Potency15.698813
GLS proteinHomo sapiens (human)Potency22.303313
glucocerebrosidaseHomo sapiens (human)Potency18.854112
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency31.3706539
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency24.3023110
Glycoprotein hormones alpha chainHomo sapiens (human)Potency6.607812
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency6.513111
heat shock protein beta-1Homo sapiens (human)Potency34.1270213
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency0.631012
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency4.614412
histone deacetylase 9 isoform 3Homo sapiens (human)Potency28.692826
Histone H2A.xCricetulus griseus (Chinese hamster)Potency42.072926
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency15.314817
huntingtin isoform 2Homo sapiens (human)Potency19.349314
hypothetical protein, conservedTrypanosoma bruceiPotency8.421812
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency22.6985214
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency59.621812
IDH1Homo sapiens (human)Potency15.734915
importin subunit beta-1 isoform 1Homo sapiens (human)Potency6.513111
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency15.3148114
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency11.220211
Integrin alpha-IIbHomo sapiens (human)Potency0.354213
Integrin beta-3Homo sapiens (human)Potency0.354213
Interferon betaHomo sapiens (human)Potency19.9844210
interleukin 8Homo sapiens (human)Potency67.267612
lamin isoform A-delta10Homo sapiens (human)Potency14.505414
lethal factor (plasmid)Bacillus anthracis str. A2012Potency2.769913
LuciferasePhotinus pyralis (common eastern firefly)Potency10.5989310
Microtubule-associated protein tauHomo sapiens (human)Potency15.645024
mitogen-activated protein kinase 1Homo sapiens (human)Potency13.874623
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency5.623411
Nrf2Homo sapiens (human)Potency12.967612
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency73.4604438
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency23.036515
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency39.986813
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency23.3620212
Nuclear receptor ROR-gammaHomo sapiens (human)Potency19.861415
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency18.7414210
nuclear receptor subfamily 1, group I, member 2Rattus norvegicus (Norway rat)Potency10.000011
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency25.9524326
P53Homo sapiens (human)Potency28.183811
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency41.726213
ParkinHomo sapiens (human)Potency13.357412
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency7.144524
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency112.0488533
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency32.1490526
phosphopantetheinyl transferaseBacillus subtilisPotency20.223813
PINK1Homo sapiens (human)Potency13.357412
plasminogen precursorMus musculus (house mouse)Potency14.256113
polyproteinZika virusPotency27.850613
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency8.912511
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency0.631011
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency10.872814
pregnane X nuclear receptorHomo sapiens (human)Potency89.2056212
pregnane X receptorRattus norvegicus (Norway rat)Potency59.701214
progesterone receptorHomo sapiens (human)Potency25.6392214
RAR-related orphan receptor gammaMus musculus (house mouse)Potency21.2588226
regulator of G-protein signaling 4Homo sapiens (human)Potency17.782811
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency21.6195333
retinoid X nuclear receptor alphaHomo sapiens (human)Potency69.2108436
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency3.995612
SMAD family member 2Homo sapiens (human)Potency13.727529
SMAD family member 3Homo sapiens (human)Potency13.727529
Smad3Homo sapiens (human)Potency13.995947
snurportin-1Homo sapiens (human)Potency6.513111
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency20.946313
survival motor neuron protein isoform dHomo sapiens (human)Potency30.305113
TAR DNA-binding protein 43Homo sapiens (human)Potency23.890213
TDP1 proteinHomo sapiens (human)Potency2.0902220
thioredoxin glutathione reductaseSchistosoma mansoniPotency89.125111
thioredoxin reductaseRattus norvegicus (Norway rat)Potency14.373012
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency13.7018327
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency32.916628
thyroid stimulating hormone receptorHomo sapiens (human)Potency23.1808726
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency38.769123
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency25.732422
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency14.256113
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency14.256113
USP1 protein, partialHomo sapiens (human)Potency55.954726
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency16.6640221
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency25.6399516
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency31.271813
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency24.3023110
VprHuman immunodeficiency virus 1Potency31.622811
WRNHomo sapiens (human)Potency31.622811

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
10 kDa chaperonin Escherichia coliIC5025.000022
10 kDa heat shock protein, mitochondrialHomo sapiens (human)IC5023.000011
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)IC5012.200011
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)IC5012.200011
5-hydroxytryptamine receptor 2AHomo sapiens (human)IC500.129011
5-hydroxytryptamine receptor 2AHomo sapiens (human)Ki0.037011
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC501.856011
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki1.181011
5-hydroxytryptamine receptor 2CHomo sapiens (human)IC501.027011
5-hydroxytryptamine receptor 2CHomo sapiens (human)Ki0.538011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)IC501.027011
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)Ki0.538011
60 kDa chaperoninEscherichia coli K-12IC50250.000011
60 kDa chaperonin Escherichia coliIC5025.000022
60 kDa heat shock protein, mitochondrialHomo sapiens (human)IC5023.000011
AcetylcholinesteraseHomo sapiens (human)IC502.246011
Adenosine receptor A1Rattus norvegicus (Norway rat)Ki187.900033
Adenosine receptor A2aRattus norvegicus (Norway rat)Ki360.750022
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC500.907011
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)Ki0.900011
Alpha-2A adrenergic receptorHomo sapiens (human)IC503.102011
Alpha-2A adrenergic receptorHomo sapiens (human)Ki1.163011
Alpha-2B adrenergic receptorHomo sapiens (human)IC500.643011
Alpha-2B adrenergic receptorHomo sapiens (human)Ki0.294011
Alpha-2C adrenergic receptorHomo sapiens (human)IC501.961011
Alpha-2C adrenergic receptorHomo sapiens (human)Ki0.285011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC501.829011
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)IC500.108511
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)Ki0.088911
Apoptotic peptidase activating factor 1Homo sapiens (human)IC5061.750022
Beta lactamase (plasmid)Pseudomonas aeruginosaIC5017.595022
Beta-carbonic anhydrase 1Mycobacterium tuberculosis H37RvKi64.000011
Bifunctional epoxide hydrolase 2Homo sapiens (human)IC500.013011
Bile salt export pumpHomo sapiens (human)IC50564.950012
Cannabinoid receptor 1Rattus norvegicus (Norway rat)Ki500.000011
Carbonic anhydraseCandida albicans SC5314Ki17.300011
Carbonic anhydraseDicentrarchus labrax (European seabass)Ki13.700011
Carbonic anhydrase Cryptococcus neoformans var. grubiiKi25.900011
Carbonic anhydrase Mycobacterium tuberculosis H37RvKi79.000011
Carbonic anhydrase 1Homo sapiens (human)IC504.630011
Carbonic anhydrase 1Homo sapiens (human)Ki91.35241537
Carbonic anhydrase 12Homo sapiens (human)Ki131.4632819
Carbonic anhydrase 13Homo sapiens (human)Ki697.000022
Carbonic anhydrase 13Mus musculus (house mouse)Ki259.3143314
Carbonic anhydrase 14Homo sapiens (human)Ki154.9625516
Carbonic anhydrase 15Mus musculus (house mouse)Ki10.500033
Carbonic anhydrase 2Homo sapiens (human)IC504.630011
Carbonic anhydrase 2Homo sapiens (human)Ki86.35211638
Carbonic anhydrase 3Bos taurus (cattle)IC504.630011
Carbonic anhydrase 3Bos taurus (cattle)Ki9.646025
Carbonic anhydrase 3Homo sapiens (human)Ki152.7625516
Carbonic anhydrase 4Homo sapiens (human)Ki108.5313830
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki206.5875516
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Ki285.1500516
Carbonic anhydrase 6Homo sapiens (human)IC504.630011
Carbonic anhydrase 6Homo sapiens (human)Ki154.0900726
Carbonic anhydrase 7Homo sapiens (human)Ki316.4625516
Carbonic anhydrase 9Homo sapiens (human)Ki125.1900920
caspase recruitment domain family, member 15Homo sapiens (human)IC501.402011
Caspase-3Homo sapiens (human)IC5046.740022
caspase-3 isoform a preproproteinHomo sapiens (human)IC5046.700011
Caspase-7Homo sapiens (human)IC50137.400011
caspase-9 isoform alpha precursorHomo sapiens (human)IC5046.700011
Chain A, Penicillin AmidohydrolaseEscherichia coliKi82.000017
Chain B, Penicillin AmidohydrolaseEscherichia coliKi82.000017
Epoxide hydrolase BMycobacterium tuberculosis CDC1551IC500.220022
KiSS-1 receptorHomo sapiens (human)Ki3.600011
large T antigenBetapolyomavirus macacaeIC5032.510012
Monoglyceride lipaseRattus norvegicus (Norway rat)IC500.306511
MPI proteinHomo sapiens (human)IC5050.000011
Muscarinic acetylcholine receptor M1Homo sapiens (human)IC500.412011
Muscarinic acetylcholine receptor M1Homo sapiens (human)Ki0.099011
Muscarinic acetylcholine receptor M2Homo sapiens (human)IC500.574011
Muscarinic acetylcholine receptor M2Homo sapiens (human)Ki0.204011
Muscarinic acetylcholine receptor M3Homo sapiens (human)IC500.383011
Muscarinic acetylcholine receptor M3Homo sapiens (human)Ki0.081011
Muscarinic acetylcholine receptor M4Homo sapiens (human)IC500.257011
Muscarinic acetylcholine receptor M4Homo sapiens (human)Ki0.036011
Muscarinic acetylcholine receptor M5Homo sapiens (human)IC500.134011
Muscarinic acetylcholine receptor M5Homo sapiens (human)Ki0.096011
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1Homo sapiens (human)IC5013.200011
NLRP3 proteinHomo sapiens (human)IC501.147522
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)IC500.108511
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)Ki0.088911
phosphomannomutase 2Homo sapiens (human)IC50100.000011
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC500.108511
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)Ki0.088911
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)IC502.084011
receptor-interacting serine/threonine-protein kinase 2 isoform 1Homo sapiens (human)IC501.402011
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC500.660011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusIC500.660011
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2Ki2.400011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusKi2.400011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC502,800.000011
Sodium-dependent dopamine transporter Homo sapiens (human)IC501.365011
Sodium-dependent dopamine transporter Homo sapiens (human)Ki1.085011
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC500.907011
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki0.900011
Sodium-dependent serotonin transporterHomo sapiens (human)IC502.438011
Sodium-dependent serotonin transporterHomo sapiens (human)Ki1.295011
Substance-K receptorHomo sapiens (human)IC501.925011
Substance-K receptorHomo sapiens (human)Ki0.642011
Thiosulfate sulfurtransferaseHomo sapiens (human)IC50100.000011
toll-like receptor 9Homo sapiens (human)IC506.339011
Tyrosine-protein kinase FynHomo sapiens (human)IC500.768011
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)Ki17,000.000011
ubiquitin-conjugating enzyme E2 NHomo sapiens (human)IC5020.000011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Chain A, Estrogen-related receptor gammaHomo sapiens (human)Kd0.788013
Chain A, Ferritin light chainEquus caballus (horse)Kd16,500.000017
Chain A, LysozymeTequatrovirus T4Kd91.000014
delta-type opioid receptorHomo sapiens (human)EC5092.461011
EndolysinTequatrovirus T4Kd98.475044
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)EC5050,500.000022
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)EC5050,500.000022
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)EC5050,500.000022
melanocortin receptor 4Homo sapiens (human)EC5089.188012
mu-type opioid receptor isoform MOR-1Homo sapiens (human)EC5092.461011
neurotensin receptor type 1Homo sapiens (human)EC504.370011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Caspase 6, apoptosis-related cysteine peptidaseHomo sapiens (human)AC506.910011
DNA repair protein RAD52 homolog isoform aHomo sapiens (human)AC5031.330011
heat shock protein 90, putativePlasmodium falciparum 3D7AC504.901011
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)AC502.311011
Polyphenol oxidase 2Agaricus bisporusKm700.000011
Sulfotransferase 1A1 Rattus norvegicus (Norway rat)Km19.000011