Page last updated: 2024-08-05 12:16:48

oligopeptide

A peptide containing a relatively small number of amino acids.

ChEBI ID: 25676

Members (100)

MemberDefinitionRole
(3S,6S,9S,12R)-3-[(2S)-Butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone(3S,6S,9S,12R)-3-[(2S)-Butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamideA secondary carboxamide resulting from the formal condensation of the carboxy group of 1H-indole-2-carboxylic acid with the primary amino group of 3-fluoro-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide. It is an inhibitor of SARS coronavirus main proteinase and inhibits SARS-CoV-2 replication in cell culture (EC50 = 0.72 muM).3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
alanyl-glutamyl-aspartic acidAla-Glu-Asp
alanyl-glycyl-glycineAla-Gly-Gly
amogastrinAmogastrin
angiotensin amideangiotensinamide
apelin-12 peptideA 12 amino acid oligopeptide fragment of apelin-13 lacking the terminal L-phenylalanine residue.apelin-12
apelin-13 peptideA 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis.apelin-13
arg-3-hyp-7-phe-bradykininA ten-membered oligopeptide comprising D-arginyl, L-arginyl, L-prolyl, (4R)-4-hydroxy-L-prolyl, glycyl, L-phenylalanyl, L-seryl, D-phenylalanyl, L-phenylalanyl and L-arginine residues joined in sequence.NPC-567
arginyl-glycyl-aspartic acidArg-Gly-Asp
arginyl-glycyl-glutamic acidArg-Gly-Glu
arginyl-glycyl-serineArg-Gly-Ser
atosibanatosiban
bms-650032asunaprevir
bradykininA linear nonapeptide messenger belonging to the kinin group of proteins, with amino acid sequence RPPGFSPFR. Enzymatically produced from kallidin in the blood, it is a powerful vasodilator that causes smooth muscle contraction, and may mediate inflammation.bradykinin
bradykinin, des-arg(9)-An eight-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, Pro and Phe residues joined in sequence. It is an analogue of bradykinin lacking the Arg residue at position 9.[des-Arg(9)]-bradykinin
bradykinin, des-phe(8)-des-arg(9)-A seven-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, and Pro residues joined in sequence by peptide bonds. It is a metabolite of bradykinin lacking the Phe residue at position 8 and the Arg residue at position 9.[des-Phe(8), des-Arg(9)]-bradykinin
bradykinin, hydroxy-pro(3)-An oligopeptide that is an analogue of bradykinin in which the third amino acid, proline, is replaced with hydroxyproline.[Hyp(3)]-bradykinin
bremelanotidebremelanotide
buserelinbuserelin
cadystin protein, s pombeA phytochelatin that is a heptapeptide consisting of 3 units of gamma-Glu-Cys, with a glycyl unit at the C-terminus.phytochelatin 3
callipeltin aA 10-membered cyclodepsipeptide containing four amino acids in the L- configuration, Ala, Leu, Thr (2 residues); one (Arg) in the D-configuration; two N-methyl amino acids, N-MeAla and N-MeGln; a methoxy tyrosine, a 3, 4-dimethyl-L-glutamine, and a 4-amino-7-guanidino-2,3 dihydroxypentanoic acid (AGDHE), formally derived from L-Arg. It is obtained from the shallow water sponge Callipelta and has been found to show activity against HIV virus.callipeltin A
ceruletideA decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.ceruletide
cetrorelixA synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-tyrosyl, N(5)-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH) antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.cetrorelix
cgp 42112aA hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist.CGP-42112A
cilengitidecilengitide
cyclo(d-tyrosyl-arginyl-arginyl-3-(2-naphthyl)alanyl-glycyl)Cyclo[3-(2-naphthalenyl)-l-alanylglycyl-d-tyrosyl-l-arginyl-l-arginyl]
davunetidedavunetide
dermorphinDermorphin
deslorelinDeslorelin
diglycyl-histidineGly-Gly-His
diprotin bVal-Pro-Leu
elastinN-Acetyl-L-leucyl-L-isoleucylglycyl-L-valyl-N-methyl-L-prolinamide
endomorphin 1L-Phenylalaninamide, L-tyrosyl-L-prolyl-L-tryptophyl-
enkephalin, ser(2), leu(5), thr(6)-DSLET
fertirelinfertirelin
gamma-glutamylfelinylglycineGamma-Glutamylfelinylglycine
glycyl-alanyl-phenylalanineGly-Ala-Phe
glycyl-glycyl-cysteineGly-Gly-Cys
glycyl-glycyl-valineGly-Gly-Val
glycyl-histidyl-glycineGly-His-Gly
glycyl-leucyl-phenylalanineGly-Leu-Phe
glycyl-leucyl-tyrosineGly-Leu-Tyr
glycyl-prolyl-arginineGly-Pro-Arg
glycyl-prolyl-glutamic acidGly-Pro-Glu
glycyl-prolyl-hydroxyprolineGlycylprolylhydroxyproline
gonadotropin-releasing hormoneA ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence.gonadorelin
goralatideAc-Ser-Asp-Lys-Pro-OH; goralatide
hemorphin 4Hemorphin-4
histrelinAn oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the diacetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.histrelin
icatibantA ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Ser, D-Tic, Oic, and Arg residues joined in sequrence. A bradykinin receptor antagonist used as its acetate salt for the treatment of acute attacks of hereditary angioedema in adult patients.icatibant
isoleucyl-prolyl-prolineIle-Pro-Pro
isoleucyl-valyl-tyrosineIle-Val-Tyr
kentsinKentsin
kinetensinAn oligopeptide comprising of nine amino acids with sequence L-Ile-L-Ala-L-Arg-L-Arg-L-His-L-Pro-L-Tyr-L-Phe-L-Leu. It was originally isolated from pepsin-treated human plasma and shares some sequence homology with the C-terminal end of neurotensin. It is a potent histamine releaser and may serve as an inflammatory mediator.kinetensin
l796778A methyl ester resulting from the formal condensation of the carboxy group of N-{[(2S)-1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl}-D-norleucyl-L-lysine with methanol. It is a partial agonist of somatostatin subtype receptor 3 (Ki = 24 nM) that exhibits anticonvulsant effects.L-796,778
leucyl-aspartyl-valineLeu-Asp-Val
leucyl-prolyl-prolineLeu-Pro-Pro
leuprolideAn oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.leuprolide
lysyl-glutamyl-aspartic acidLys-Glu-Asp
lysyl-tryptophyl-alpha-lysineLys-Trp-Lys
lysyl-tyrosyl-lysineLys-Tyr-Lys
methionyl-leucyl-phenylalanineMet-Leu-Phe
montirelinMontirelin
morphiceptinMorphiceptin
msh (11-13)Lys-Pro-Val
msh release-inhibiting hormoneMelanostatin
N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamideA secondary carboxamide resulting from the formal condensation of the carboxy group of 1H-indole-2-carboxylic acid with the primary amino group of 3-cyclohexyl-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide. It is an inhibitor of SARS coronavirus main proteinase and inhibits SARS-CoV-2 replication in cell culture (EC50 = 0.53 muM).N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide
nafarelinAn oligopeptide comprising of 5-oxo-L-proline, L-histidine, L-tryptophan, L-serine, L-tyrosine, 3-(2-naphthyl)-D-alanine, L-leucine, L-arginine and L-prolylglycinamide residues joined sequence by peptide linkages. It is a gonadotropin releasing hormone agonist that is used to treat central precocious puberty in children and endometriosis in women.nafarelin
p 829depreotide
pentigidepentigetide
phakellistatin 13Phakellistatin 13
phenylalanyl-phenylalanyl-glycinePhe-Phe-Gly
phenylalanyl-phenylalanyl-phenylalaninePhe-Phe-Phe
phenylalanyl-prolyl-argininePhe-Pro-Arg
phomopsinPhomopsin A
posatirelinposatirelin
prolyl-glycyl-glycinePro-Gly-Gly
prolyl-leucyl-glycinePro-Leu-Gly
prolyl-prolyl-glycinePro-Pro-Gly
pyroglutamyl-glutamyl-proline amidePglu-glu-pro-amide
rgh 0205Arg-Lys-Asp
rhizonin aRhizonin A
riginRigin
s-(2-chloroethyl)glutathioneS-(2-Chloroethyl)glutathione
s-benzoylmercaptoacetyltriglycinebetiatide
s-ethyl glutathioneGlutathione ethyl ester
saralasinsaralasin
seryl-lysyl-leucineSer-Lys-Leu
sincalidesincalide
spinorphinSpinorphin
splenopentinArg-Lys-Glu-Val-Tyr
splenotritinArg-Lys-Glu
ta 0910An oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy.taltirelin
teicoplanin aglyconeteicoplanin aglycone
telaprevirAn oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.telaprevir
thymopentinthymopentin
trimethionineMet-Met-Met
ulimorelinUlimorelin
ustiloxin dUstiloxin D

Research

Studies (45,419)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199012,490 (27.50)18.7374
1990's11,853 (26.10)18.2507
2000's9,465 (20.84)29.6817
2010's9,421 (20.74)24.3611
2020's2,190 (4.82)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials2,626 (5.39%)5.53%
Reviews3,259 (6.69%)6.00%
Case Studies1,288 (2.64%)4.05%
Observational99 (0.20%)0.25%
Other41,478 (85.08%)84.16%