A class of sulfonamides whose members generally have bacteriostatic antibiotic properties.
| Member | Definition | Role |
|---|
| phthalylsulfathiazole | A sulfonamide incorporating 2-carboxybenzamido and 1,3-thiazol-2-yl moieties that is a broad-spectrum antibiotic indicated in the treatment of dysentery, colitis, gastroenteritis and intestinal surgery. | phthalylsulfathiazole |
| sulfabenzamide | A sulfonamide containing a benzamido substituent on nitrogen. An antibacterial/antimicrobial, it is often used in conjunction with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation. | sulfabenzamide |
| sulfadiazine | A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position. | sulfadiazine |
| sulfadimethoxine | A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. | sulfadimethoxine |
| sulfaguanidine | A sulfonamide incorporating a guanidine moiety used to block the synthesis of folic acid; mostly used in veterinary medicine | sulfaguanidine |
| sulfalene | | sulfamethopyrazine |
| sulfamerazine | A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamerazine |
| sulfameter | A sulfonamide consisting of pyrimidine having a methoxy substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamethoxydiazine |
| sulfamethazine | A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamethazine |
| sulfamethizole | A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2. | sulfamethizole |
| sulfamethoxazole | An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. | sulfamethoxazole |
| sulfamethoxypyridazine | A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position. | sulfamethoxypyridazine |
| sulfametrole | A sulfonamide obtained by formal condensation of the sulfo group of 4-aminobenzenesulfonic acid with the amino group of 4-methoxy-1,2,5-thiadiazol-3-amine. | sulfametrole |
| sulfamoxole | A sulfonamide antibiotic in which 4-aminobenzenesulfonic acid and 4,5-dimethyl-1,3-oxazol-2-amine have combined to form the sulfonamide bond. | sulfamoxole |
| sulfanilamide | A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. | sulfanilamide |
| sulfaperine | A substituted aniline that is sulfanilamide in which on of the hydrogens of the sulfonamide group has been replaced by a 5-methylpyrimidin-2-yl group. | sulfaperin |
| sulfaphenazole | A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent. | sulfaphenazole |
| sulfapyridine | A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position. | sulfapyridine |
| sulfathiazole | A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position. | sulfathiazole |
| sulfathiourea | A substituted aniline that is thiourea in which one of the hydrogens has been replaced by a (p-aminophenyl)sulfonyl group. | sulfathiourea |
| sulfisomidine | A sulfonamide consisting of pyrimidine having methyl substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. | sulfisomidine |
| sulfisoxazole | A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. | sulfisoxazole |
| trichlormethiazide | A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension. | trichlormethiazide |