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hydroxymethylpyridine
Any member of the class of pyridines carrying a hydroxymethyl substituent at unspecified position.
ChEBI ID: 38196
Members (5)
Member | Definition | Role |
---|---|---|
4-deoxypyridoxine | A pyridine ring substituted with methyl groups at positions 2 and 4, a hydroxyl at position 3, and a hydroxymethyl group at position 5. | 4-deoxypyridoxine |
pyridoxal | A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxal |
pyridoxamine | A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. | pyridoxamine |
pyridoxic acid | A methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine. | 4-pyridoxic acid |
pyridoxine | A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxine |
Research
Studies (8,451)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 5,439 (64.36) | 18.7374 |
1990's | 1,184 (14.01) | 18.2507 |
2000's | 839 (9.93) | 29.6817 |
2010's | 688 (8.14) | 24.3611 |
2020's | 301 (3.56) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 511 (5.15%) | 5.53% |
Reviews | 761 (7.66%) | 6.00% |
Case Studies | 661 (6.66%) | 4.05% |
Observational | 4 (0.04%) | 0.25% |
Other | 7,993 (80.49%) | 84.16% |