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prostanoid
The family of natural prostaglandins and prostaglandin-like compounds including prostacyclins and thromboxanes.
ChEBI ID: 26347
Members (25)
| Member | Definition | Role |
|---|
| 11-deoxyprostaglandin e1 | | 11-deoxyprostaglandin E1 |
| 13,14-dihydroprostaglandin e1 | | 13,14-Dihydro PGE1 |
| 15(s)-15-methylprostaglandin e1 | | 15-Methyl-15S-Prostaglandin E1 |
| 16,16-dimethylprostaglandin e | | 16,16-dimethyl-PGE1 |
| 16,16-dimethylprostaglandin e2 | A prostanoid that is prostaglandin E2 in which both of the hydrogens at position 16 have been replaced by methyl groups. A synthetic analogue of prostaglandin E2, it is a potent inhibitor of pancreatic function and growth of experimental tumors. It also protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. | 16,16-dimethylprostaglandin E2 |
| 17-phenyltrinorprostaglandin e2 | A prostanoid that is 18,19,20-trinor-prostaglandin E2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group. | 17-phenyl-18,19,20-trinor-prostaglandin E2 |
| 2,3-dinor-6-ketoprostaglandin f1alpha | A prostanoid that is prostaglandin F1alpha lacking two methylenes in the carboxyalkyl chain and bearing an oxo group at the 6-position. | 2,3-dinor-6-oxoprostaglandin F1alpha |
| 7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid | | Prostaglandin M |
| 8-iso-prostaglandin a2 | | 8-iso Prostaglandin A2 |
| 8-isoprostaglandin e2 | A prostanoid that is prostaglandin E2 having inverted stereochemistry at the 8-position. | 8-epi-prostaglandin E2 |
| arbaprostil | | 15-methyl-15R-PGE2 |
| bicyclo-PGE2 | | bicyclo-PGE2 |
| carboprostacyclin | | Carbaprostacyclin |
| ciprostene | | Ciprostene |
| cloprostenol | | Cloprostenol |
| epoprostenol sodium | | Epoprostenol sodium |
| prostaglandin e2 ethanolamide | | Prostaglandin E2 ethanolamide |
| prostaglandin e2 methyl ester | | Prostaglandin E2 methyl ester |
| prostaglandin f2 isopropyl ester | | PGF2alpha isopropyl ester |
| prostaglandin f2 methyl ester | | PGF2alpha methyl ester |
| prostaglandin i3 | | PGI3 |
| rosaprostol | | rosaprostol |
| sulprostone | | sulprostone |
| tiaprost | | Tiaprost |
| u 44069 | | U-44069 |
Research
Studies (3,125)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 1,027 (32.86) | 18.7374 |
| 1990's | 704 (22.53) | 18.2507 |
| 2000's | 828 (26.50) | 29.6817 |
| 2010's | 501 (16.03) | 24.3611 |
| 2020's | 65 (2.08) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 551 (16.23%) | 5.53% |
| Reviews | 114 (3.36%) | 6.00% |
| Case Studies | 111 (3.27%) | 4.05% |
| Observational | 7 (0.21%) | 0.25% |
| Other | 2,611 (76.93%) | 84.16% |