Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 2,818.3800 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 11.6000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 2,400.0000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | IC50 | 331.1310 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 2,779.9967 | 3 | 3 |
| Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (human) | IC50 | 154.5000 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 378.8895 | 4 | 4 |
| Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (human) | IC50 | 41.2000 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 55.3998 | 3 | 3 |