Page last updated: 2024-09-28

Salpingitis

Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)

Synonyms(1)

Synonym
Salpingitis

Research Excerpts

Overview

ExcerptReference
"Chronic salpingitis is highly associated with the presence of C."( Bobo, LD; Hinton, EL; Kurman, RJ; Viscidi, RP; Wu, TC, 2000)
"Salpingitis is a common cause for subfertility and infertility both in humans and animals."( Kölle, S; Owhor, LE; Reese, S, 2019)

Treatment

ExcerptReference
"Conservative treatment of acute salpingitis should be the rule, surgery the exception."( Mårdh, PA; Svensson, L, 1982)

Research

Studies (267)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990196 (73.41)23.3326
1990's34 (12.73)12.5806
2000's14 (5.24)18.1394
2010's17 (6.37)28.8240
2020's6 (2.25)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dimethyl sulfoxide0low10
formaldehyde0low10
iodine0low10
orotic acid0low20
phosphorylcholine0low10
3,4-methylenedioxyamphetamine0low10
beta-aminoethyl isothiourea0low10
antipyrine0low10
azathioprine0low10
cefuroxime0low10
ciprofloxacin0medium41
erythrosine0low10
fluconazole0low10
gentamicin0medium128
guaifenesin0low20
ibuprofen0low10
iohexol0low10
ioxaglate0low10
ioxilan0low10
isoniazid0low40
isoproterenol0low10
khellin0low10
methyl parathion0low10
metronidazole0medium194
ofloxacin0medium87
oxyphenbutazone0low20
aminosalicylic acid0low10
phenylbutazone0low10
probenecid0medium101
procaine0low10
sulfamethoxazole0medium62
sulfanilamide0low40
trimethoprim0medium52
prednisolone0medium41
estriol0low20
thymidine0low10
prednisone0low10
estrone0low30
dehydroepiandrosterone0low30
penicillin g0medium155
metaraminol0low20
chloramphenicol0low40
methyltestosterone0low20
adenosine diphosphate0low10
cephalothin0low20
kanamycin a0low30
carbostyril0low10
levodopa0low20
niridazole0low10
uridine triphosphate0low10
etimizol0low20
ampicillin0medium308
medroxyprogesterone acetate0low10
valine0low10
methylprednisolone0low10
penicillin v0low10
penicillanic acid0medium22
acrylonitrile0low10
diatrizoate meglumine0low10
pregnenolone0low10
acridines0low10
nandrolone0low20
medroxyprogesterone0low10
azomycin0low10
erythromycin0medium91
dehydroepiandrosterone sulfate0low10
levonorgestrel0low10
benzohexonium0low10
ethambutol0low10
spectinomycin0low90
streptomycin0medium121
technetium0low20
magnesium sulfate0medium11
silver nitrate0low10
trolamine salicylate0low80
levamisole0medium31
thiamphenicol0low10
danazol0low10
phenyl acetate0low10
triamcinolone0low10
cefazolin0low10
pivampicillin0medium32
amoxicillin0medium159
tobramycin0low10
ticarcillin0medium22
ribavirin0low10
piperacillin0medium33
buserelin0low10
cefotetan0low10
clinafloxacin0low10
norvaline0low10
iopamidol0low10
cephalosporin c0medium111
delphinidin0low20
fluorodeoxyglucose f180low10
dienogest0low10
alpha,beta-methyleneadenosine 5'-triphosphate0low10
glycidyl nitrate0low10
imipenem, anhydrous0medium21
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
emoxypine succinate0low10
sulbactam0medium44
beta-lactams0low10
moxifloxacin0low20
paromomycin0medium11
cortisone0low30
nandrolone phenpropionate0low10
allylestrenol0low10
trimethoprim, sulfamethoxazole drug combination0medium22
glycogen0low10
fibrin0low10
oxytocin0low10
cefoxitin0medium116
erythromycin ethylsuccinate0low10
4-nitrophenylphosphorylcholine0low10
clindamycin0medium125
zithromax0medium31
diethylstilbestrol0low60
cefamandole0low10
dibekacin0low10
mezlocillin0medium21
polidocanol0low10
iothalamate meglumine0low10
thiouracil0low10
enclomiphene0low20
thiourea0low10
estrone sulfate0low10
zinc oxide0low10
thymic factor, circulating0medium11
ovalbumin0low10
alpha-chymotrypsin0low30
17-ketosteroids0low30
icodextrin0low10
noxythiolin0low10
benzyl cinnamate0low10
dinoprostone0low20
dinoprost0low20
leukotriene b40low10
5-hydroxy-6,8,11,14-eicosatetraenoic acid0low10
6-ketoprostaglandin f1 alpha0low10
clavulanic acid0medium33
thromboxane b20low10
arachidonic acid 5-hydroperoxide0low10
2-methylthio-atp0low10
indium0low10
sulfur0low10
silicon0low10
phosphorus0low10
cefotaxime0medium43
pregnanediol0low20
cilastatin0low10
amoxicillin-potassium clavulanate combination0medium107
acid phosphatase0low20
neuropeptide y0low10
cefamandole nafate, monosodium salt, 14c-labeled, (6r-(6alpha,7beta,(r*)))-isomer0low10
chlorophyll a0low10
menotropins0low10
sodium tetradecyl sulfate0low10
ro13-99040medium32
sodium ethylxanthate0low10
elafin0medium11
thymosin0low10
colistin0low10
vasoactive intestinal peptide0low10
tetracycline0medium273
oxytetracycline, anhydrous0low20
minocycline0low20
piroxicam0medium11
demeclocycline0medium11
mysteclin f0low10
lymecycline0low20
technetium tc 99m lidofenin0low20
hyaluronoglucosaminidase0low20
adrenomedullin0low10
lactoferrin0low10
muramidase0low10
exudates0low10
rifampin0low20
ridostin0medium11

Protein Targets (1,040)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE250025
Chain A, Cruzipain6006
regulator of G-protein signaling 4120012
Platelet-activating factor receptor0202
Inositol monophosphatase 16006
S-adenosylmethionine synthase isoform type-10202
S-adenosylmethionine synthase isoform type-20202
Ectonucleotide pyrophosphatase/phosphodiesterase family member 10202
Mu-type opioid receptor0639
Delta-type opioid receptor0235
Kappa-type opioid receptor0639
P2X purinoceptor 10033
P2Y purinoceptor 10033
P2Y purinoceptor 10011
P2Y purinoceptor 10033
P2X purinoceptor 20022
P2X purinoceptor 10033
P2X purinoceptor 40033
P2X purinoceptor 50033
P2X purinoceptor 60033
P2X purinoceptor 30033
P2Y purinoceptor 60033
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 0202
P2Y purinoceptor 110033
P2X purinoceptor 40011
P2Y purinoceptor 120033
P2X purinoceptor 40011
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 2A0516
5-hydroxytryptamine receptor 1A0213
Sodium-dependent noradrenaline transporter 012012
Sodium-dependent dopamine transporter0022
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0011
5-hydroxytryptamine receptor 1F0011
5-hydroxytryptamine receptor 2B0314
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter018119
Sodium-dependent serotonin transporter0112
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
Sodium-dependent dopamine transporter 010010
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain H, Protein (antibody M3c65 (heavy Chain))0011
Chain L, Protein (antibody M3c65 (light Chain))0011
Microtubule-associated protein tau160016
Polyunsaturated fatty acid 5-lipoxygenase0303
Solute carrier organic anion transporter family member 2A10106
Chain A, Ferritin light chain5005
thioredoxin reductase200020
TDP1 protein440044
Smad38008
aldehyde dehydrogenase 1 family, member A1260026
alpha-galactosidase4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1110011
flap endonuclease 1110011
DNA polymerase iota isoform a (long)170017
DNA topoisomerase 2-alpha0106
Acetylcholinesterase0404
GLI family zinc finger 3450045
thyroid stimulating hormone receptor160016
retinoic acid nuclear receptor alpha variant 1360036
estrogen nuclear receptor alpha640064
thyroid hormone receptor beta isoform 2370037
Cellular tumor antigen p53290029
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0112
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0202
Endoplasmin0112
P2Y purinoceptor 20022
Phosphatidylinositol 4-kinase alpha0202
Heat shock protein 75 kDa, mitochondrial0101
Phosphatidylinositol 4-kinase type 2-beta0202
Phosphatidylinositol 4-kinase type 2-alpha0202
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
AR protein540054
glucocorticoid receptor [Homo sapiens]430043
pregnane X nuclear receptor360036
Chain A, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Chain A, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Chain A, Calmodulin-sensitive adenylate cyclase0101
Chain A, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
phosphopantetheinyl transferase160016
P2X purinoceptor 70011
peroxisome proliferator activated receptor gamma270027
ATP-binding cassette sub-family C member 3033033
Multidrug resistance-associated protein 4035039
Bile salt export pump054054
Thromboxane-A synthase 0202
Prostaglandin E2 receptor EP3 subtype0202
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin E2 receptor EP1 subtype0202
Prostacyclin receptor0426
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0213
Canalicular multispecific organic anion transporter 1033033
Solute carrier organic anion transporter family member 2A10105
Solute carrier organic anion transporter family member 2B10202
Solute carrier organic anion transporter family member 3A10001
Chain A, 2-oxoglutarate Oxygenase9009
thioredoxin glutathione reductase8008
euchromatic histone-lysine N-methyltransferase 2320032
microphthalmia-associated transcription factor isoform 90404
Carbonic anhydrase 1010012
Carbonic anhydrase 2010113
Tyrosine-protein phosphatase non-receptor type 10012
Chain A, Beta-lactamase150015
Beta-lactamase 0106
Beta-lactamase 0108
Beta-lactamase 0008
Beta-lactamase 02010
apical membrane antigen 1, AMA16006
Beta-lactamase 0004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 17007
DNA polymerase eta isoform 16006
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
DNA polymerase kappa isoform 1110011
Bile salt export pump012012
Beta-lactamase SHV-10107
Beta-lactamase SHV-103010
Cytochrome P450 2C9 016016
Beta-lactamase0209
Kappa-type opioid receptor0007
Solute carrier family 15 member 1012012
Solute carrier family 15 member 10202
Cytochrome P450 2J2012012
B2 metallo-beta-lactamase 0005
Solute carrier family 15 member 20606
Beta-lactamase 0107
Beta-lactamase 0107
Solute carrier family 15 member 20606
Beta-lactamase 0107
Beta-lactamase 0007
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
Beta-lactamase 0307
acid sphingomyelinase2002
GLS protein180018
farnesoid X nuclear receptor230023
Beta-lactamase 0308
Beta-lactamase 0007
Metallo-beta-lactamase type 20007
Metallo-beta-lactamase VIM-11 0006
Metallo-beta-lactamase VIM-20006
Beta-lactamase 0108
Metallo-beta-lactamase0007
Beta-lactamase 0308
chromobox protein homolog 1290029
DNA polymerase beta5005
geminin440044
60 kDa heat shock protein, mitochondrial0303
Beta-lactamase OXA-70004
Spike glycoprotein140115
10 kDa heat shock protein, mitochondrial0303
Angiopoietin-1 receptor0011
Beta-lactamase 0207
Beta-lactamase 0207
Beta-lactamase 0207
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130006
Efflux transporter 0003
Beta-lactamase 0006
Beta-lactamase Toho-10004
Beta-lactamase 0003
Class D beta-lactamase0205
60 kDa chaperonin 0303
Metallo-beta-lactamase0005
Beta-lactamase 0208
Beta-lactamase 0003
10 kDa chaperonin 0303
Metallo-b-lactamase 0009
Carbapenem-hydrolyzing beta-lactamase KPC03010
Histamine H3 receptor0006
Beta-lactamase class B VIM-2 0009
Beta-lactamase VIM-1 0006
ATP-dependent phosphofructokinase110011
ATAD5 protein, partial120012
USP1 protein, partial160016
nuclear receptor subfamily 1, group I, member 3280028
retinoid X nuclear receptor alpha340034
67.9K protein7007
peroxisome proliferator-activated receptor delta180018
thyroid hormone receptor beta isoform a100010
nuclear factor erythroid 2-related factor 2 isoform 2100010
nuclear factor erythroid 2-related factor 2 isoform 1410041
Nicotinate phosphoribosyltransferase0303
Chain A, TYROSYL-DNA PHOSPHODIESTERASE100010
interleukin 8100010
acetylcholinesterase110011
RAR-related orphan receptor gamma310031
SMAD family member 2160016
Fumarate hydratase5005
SMAD family member 3160016
EWS/FLI fusion protein140014
estrogen-related nuclear receptor alpha420042
G230023
polyprotein5005
P531001
arylsulfatase A110011
IDH1110011
aryl hydrocarbon receptor150015
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a260026
thyroid stimulating hormone receptor170017
activating transcription factor 6140014
v-jun sarcoma virus 17 oncogene homolog (avian)210021
Histone H2A.x150015
Bloom syndrome protein isoform 18008
peripheral myelin protein 22 isoform 16006
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a5005
heat shock protein beta-1170017
peripheral myelin protein 22120012
survival motor neuron protein isoform d110011
cytochrome P450 3A4 isoform 1180018
M-phase phosphoprotein 86006
muscleblind-like protein 1 isoform 18008
muscarinic acetylcholine receptor M18008
lamin isoform A-delta10230023
Gamma-aminobutyric acid receptor subunit pi182021
Voltage-dependent calcium channel gamma-2 subunit180018
Interferon beta270027
HLA class I histocompatibility antigen, B alpha chain 230023
Gamma-aminobutyric acid receptor subunit beta-1182021
Gamma-aminobutyric acid receptor subunit delta182021
Gamma-aminobutyric acid receptor subunit gamma-2182021
Glutamate receptor 2180018
Gamma-aminobutyric acid receptor subunit alpha-5182021
Gamma-aminobutyric acid receptor subunit alpha-3182021
Gamma-aminobutyric acid receptor subunit gamma-1182021
Gamma-aminobutyric acid receptor subunit alpha-2182021
Gamma-aminobutyric acid receptor subunit alpha-4182021
Gamma-aminobutyric acid receptor subunit gamma-3182021
Gamma-aminobutyric acid receptor subunit alpha-6182021
Nuclear receptor ROR-gamma9009
Gamma-aminobutyric acid receptor subunit alpha-1182021
Gamma-aminobutyric acid receptor subunit beta-3182021
Gamma-aminobutyric acid receptor subunit beta-2182021
GABA theta subunit182021
Inositol hexakisphosphate kinase 1230023
ATPase family AAA domain-containing protein 59009
Ataxin-2100010
Gamma-aminobutyric acid receptor subunit epsilon182021
Protein-arginine deiminase type-4010010
cytochrome P450 2C9, partial230023
Luciferase160016
cytochrome P450 family 3 subfamily A polypeptide 4280028
potassium voltage-gated channel subfamily H member 2 isoform d7007
17beta-hydroxysteroid dehydrogenase0101
Chain A, Putative fructose-1,6-bisphosphate aldolase9009
cytochrome P450 2C19 precursor4004
lethal factor (plasmid)4004
Nitric oxide synthase, brain0101
Carbonic anhydrase 40405
Carbonic anhydrase0304
Carbonic anhydrase 150304
Chain A, serum paraoxonase0101
nuclear receptor ROR-gamma isoform 1100010
Carbonic anhydrase 120304
Carbonic anhydrase 30203
Neutrophil cytosol factor 10101
Carbonic anhydrase 60304
Carbonic anhydrase 5A, mitochondrial0305
Carbonic anhydrase 70203
Carbonic anhydrase 90405
Carbonic anhydrase 130202
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140203
Carbonic anhydrase 5B, mitochondrial0204
Solute carrier family 22 member 6011011
Solute carrier family 22 member 6012014
Solute carrier family 22 member 70406
Solute carrier family 22 member 8012016
Solute carrier family 22 member 1107012
Solute carrier family 22 member 809011
Solute carrier family 22 member 70508
Chain A, JmjC domain-containing histone demethylation protein 3A110011
cytochrome P450 2D6170017
vitamin D3 receptor isoform VDRA170017
Beta-lactamase 0206
Beta-lactamase 0306
Metallo-beta-lactamase VIM-19 0005
Beta-lactamase 0206
Albumin0167
Beta-lactamase 0002
Beta-lactamase 0206
Metallo-beta-lactamase VIM-20006
BlaVIM-1 0005
Beta-lactamase 0002
Beta-lactamase 0104
bromodomain adjacent to zinc finger domain 2B100010
parathyroid hormone/parathyroid hormone-related peptide receptor precursor100010
lethal(3)malignant brain tumor-like protein 1 isoform I2002
DNA dC->dU-editing enzyme APOBEC-3G isoform 13104
DNA dC->dU-editing enzyme APOBEC-3A isoform a0101
TAR DNA-binding protein 43140014
Solute carrier family 22 member 80607
endonuclease IV5005
WRN3003
DNA (cytosine-5)-methyltransferase 1 isoform b0101
importin subunit beta-1 isoform 15005
serine/threonine-protein kinase PLK15005
snurportin-15005
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10101
Beta-lactamase0204
Beta-lactamase0205
Beta-lactamase OXA-10203
Beta-lactamase TEM0509
Beta-lactamase 0105
phosphoglycerate kinase3003
vitamin D (1,25- dihydroxyvitamin D3) receptor270027
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a160016
streptokinase A precursor0088
Dihydroxyacetone phosphate acyltransferase0002
30S ribosomal protein S60617
30S ribosomal protein S70617
50S ribosomal protein L150617
Cytochrome P450 3A4010111
50S ribosomal protein L100617
50S ribosomal protein L110617
50S ribosomal protein L7/L120617
50S ribosomal protein L190617
50S ribosomal protein L10617
50S ribosomal protein L200617
50S ribosomal protein L270617
50S ribosomal protein L280617
50S ribosomal protein L290617
50S ribosomal protein L310617
50S ribosomal protein L31 type B0617
50S ribosomal protein L320617
50S ribosomal protein L330617
50S ribosomal protein L340617
50S ribosomal protein L350617
50S ribosomal protein L360617
30S ribosomal protein S100617
30S ribosomal protein S110617
30S ribosomal protein S120617
30S ribosomal protein S130617
30S ribosomal protein S160617
30S ribosomal protein S180617
30S ribosomal protein S190617
30S ribosomal protein S200617
30S ribosomal protein S20617
30S ribosomal protein S30617
30S ribosomal protein S40617
30S ribosomal protein S50617
30S ribosomal protein S80617
30S ribosomal protein S90617
50S ribosomal protein L130617
50S ribosomal protein L140617
50S ribosomal protein L160617
50S ribosomal protein L230617
30S ribosomal protein S150617
50S ribosomal protein L170617
50S ribosomal protein L210617
50S ribosomal protein L300617
50S ribosomal protein L60617
30S ribosomal protein S140617
30S ribosomal protein S170617
30S ribosomal protein S10617
50S ribosomal protein L180617
50S ribosomal protein L20617
50S ribosomal protein L30617
50S ribosomal protein L240617
50S ribosomal protein L40617
50S ribosomal protein L220617
50S ribosomal protein L50617
30S ribosomal protein S210617
50S ribosomal protein L250617
50S ribosomal protein L36 20617
Methionine--tRNA ligase, mitochondrial0011
Beta-2 adrenergic receptor0314
Beta-1 adrenergic receptor0315
Dipeptidase 10101
Beta-3 adrenergic receptor0213
Chain A, HADH2 protein120012
Chain B, HADH2 protein120012
cytochrome P450 2C9 precursor4004
Cytochrome P450 1A20505
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0203
DNA gyrase subunit A0408
DNA gyrase subunit B0408
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0203
Cytochrome P450 2D60303
DNA gyrase subunit A0203
Cytochrome P450 2C190404
Multidrug resistance protein MdtK0011
Histamine H2 receptor6017
DNA gyrase subunit B0507
DNA gyrase subunit A0507
Enoyl-[acyl-carrier-protein] reductase [NADH]0206
Potassium voltage-gated channel subfamily H member 20709
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0303
Beta-lactamase 0202
Beta-lactamase0303
Neutrophil elastase0101
Cytochrome P450 2B60213
Beta-lactamase0101
Beta-lactamase 0101
Beta-lactamase 0101
DNA repair and recombination protein RAD54-like isoform 10001
twin arginine protein translocation system - TatA protein0002
dopamine D1 receptor5005
pregnane X receptor7007
progesterone receptor290029
atrial natriuretic peptide receptor 1 precursor3003
Glucocorticoid receptor026334
Sex hormone-binding globulin001111
Glycine receptor subunit alpha-1026026
Corticosteroid-binding globulin0707
Glycine receptor subunit beta026026
Glycine receptor subunit alpha-2026026
Glycine receptor subunit alpha-3026026
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10303
glp-1 receptor, partial8008
hypoxia-inducible factor 1 alpha subunit120012
estrogen receptor 2 (ER beta)220022
nuclear receptor subfamily 1, group I, member 27007
Rap guanine nucleotide exchange factor 38008
Estrogen receptor019424
Aldo-keto reductase family 1 member B1010010
Alpha-2A adrenergic receptor0606
Adenosine receptor A30909
Beta-3 adrenergic receptor0516
Androgen receptor024024
Alpha-1B adrenergic receptor011011
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0606
Muscarinic acetylcholine receptor M30606
Substance-K receptor0606
D(1A) dopamine receptor0505
5-hydroxytryptamine receptor 2A0606
D(3) dopamine receptor0707
Alpha-1A adrenergic receptor011011
Beta-glucuronidase0101
Beta-glucuronidase0101
Glucose-6-phosphate 1-dehydrogenase0404
Alpha-synuclein55010
G-protein coupled bile acid receptor 10022
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Solute carrier organic anion transporter family member 1A40406
Solute carrier organic anion transporter family member 1A50003
Steryl-sulfatase0305
Multidrug resistance-associated protein 1 0103
Solute carrier organic anion transporter family member 1A10709
Solute carrier organic anion transporter family member 1A20204
Solute carrier organic anion transporter family member 1A30001
ATP-binding cassette sub-family C member 110001
Solute carrier organic anion transporter family member 1B30507
Solute carrier organic anion transporter family member 1A10002
Solute carrier organic anion transporter family member 1B20003
Solute carrier organic anion transporter family member 1B107010
Epidermal growth factor receptor0404
Vascular endothelial growth factor receptor 20101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
CREB-binding protein0101
hexokinase-4 isoform 14004
glucokinase regulatory protein4004
Hsf1 protein0011
15-lipoxygenase, partial4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
mitogen-activated protein kinase 16006
ubiquitin carboxyl-terminal hydrolase 2 isoform a7007
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
high affinity choline transporter 1 isoform a0101
neuropeptide S receptor isoform A4004
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
5-hydroxytryptamine receptor 40404
Nuclear receptor subfamily 1 group I member 20123
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Integrin beta-32002
Tyrosine-protein kinase Fyn0303
Integrin alpha-IIb2002
Beta-1 adrenergic receptor0415
Muscarinic acetylcholine receptor M10405
Polyunsaturated fatty acid lipoxygenase ALOX150707
D(2) dopamine receptor0303
Prostaglandin G/H synthase 10606
Alpha-1D adrenergic receptor0213
5-hydroxytryptamine receptor 2C0404
Adenosine receptor A2a0505
Adenosine receptor A10303
Vasopressin V1a receptor0415
5-hydroxytryptamine receptor 2B0606
5-hydroxytryptamine receptor 60404
Estrogen-related receptor gamma0011
Disintegrin and metalloproteinase domain-containing protein 173003
Aldehyde oxidase0202
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140101
Estrogen receptor beta07412
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Cysteinyl leukotriene receptor 10202
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Solute carrier family 22 member 20103
Solute carrier family 22 member 1 0204
Prostaglandin G/H synthase 1 0404
Prostaglandin G/H synthase 2 0303
Thromboxane A2 receptor 0123
Prostaglandin E2 receptor EP1 subtype0325
Prostaglandin G/H synthase 20606
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0224
Prostaglandin E2 receptor EP3 subtype0325
Prostaglandin E2 receptor EP2 subtype0314
Prostaglandin F2-alpha receptor0011
Prostaglandin D2 receptor0101
Solute carrier organic anion transporter family member 2A10101
prostaglandin E2 receptor EP2 subtype1001
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 200505
Solute carrier family 22 member 60505
Solute carrier family 22 member 70001
chaperonin-containing TCP-1 beta subunit homolog2002
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0001
Receptor tyrosine-protein kinase erbB-20101
Muscarinic acetylcholine receptor M20304
Muscarinic acetylcholine receptor M40203
Muscarinic acetylcholine receptor M50202
C-8 sterol isomerase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10202
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
Motilin receptor0112
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10303
60 kDa chaperonin0101
Chitinase B0101
ATP-dependent translocase ABCB10303
Low molecular weight phosphotyrosine protein phosphatase0101
Cytochrome P450 1B10303
Lanosterol 14-alpha demethylase0516
exodeoxyribonuclease V subunit RecD0202
exodeoxyribonuclease V subunit RecB0202
exodeoxyribonuclease V subunit RecC0202
Genome polyprotein 0112
hypothetical protein, conserved3003
thyrotropin-releasing hormone receptor1001
eyes absent homolog 2 isoform a1001
histone acetyltransferase KAT2A isoform 18008
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
UDP-glucuronosyltransferase 2B70002
Lanosterol 14-alpha demethylase0022
Olfactory receptor 51E20011
UDP-glucuronosyltransferase 1A100102
NFKB1 protein, partial6006
GALC protein4004
nonstructural protein 16006
Aromatase0202
17-beta-hydroxysteroid dehydrogenase type 10203
Mu-type opioid receptor0112
Mu-type opioid receptor0314
Ghrelin O-acyltransferase0101
Estrogen receptor beta0001
Solute carrier organic anion transporter family member 2B1 0304
Estrogen receptor0001
Sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member0001
Solute carrier organic anion transporter family member 1C10202
Pantothenate synthetase0202
PPM1D protein3003
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
lysosomal alpha-glucosidase preproprotein2002
Vpr1001
Cytochrome P450 2B10101
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
UDP-glucuronosyltransferase 1A1 0203
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sulfotransferase 1A10214
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20101
Chain A, BCL-2-RELATED PROTEIN A10011
unnamed protein product0101
transcriptional regulator ERG isoform 36006
heat shock protein HSP 90-alpha isoform 20102
bcl-2-like protein 11 isoform 10011
Histone deacetylase 30101
Chymotrypsinogen A0101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
Lanosterol 14-alpha demethylase0112
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Histone deacetylase 40101
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10101
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
14-alpha sterol demethylase 0011
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
Menin0011
Lecithin retinol acyltransferase0101
Lethal factor0101
Protein Rev 0022
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10202
Uracil nucleotide/cysteinyl leukotriene receptor0101
Acid-sensing ion channel 30101
Dihydrofolate reductase0404
Fatty acid-binding protein, liver0202
Albumin0101
Albumin0011
Prostaglandin G/H synthase 10505
Cholinesterase0202
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0306
Prostaglandin G/H synthase 10101
Adenosine receptor A10203
Caspase-10303
Adenosine receptor A2a0203
Substance-P receptor0101
Prostaglandin G/H synthase 2 0406
UDP-glucuronosyltransferase 1A30001
Aldo-keto reductase family 1 member C30303
Caspase-30202
Caspase-40202
4-aminobutyrate aminotransferase, mitochondrial0101
Caspase-50202
Caspase-90202
Acid-sensing ion channel 10101
Prostaglandin G/H synthase 20303
Fatty-acid amide hydrolase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0406
Dehydrogenase/reductase SDR family member 90101
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase IMP-1 0002
Beta-lactamase 0002
histone deacetylase 9 isoform 32002
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
cytochrome P450 2D6 isoform 14004
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20102
Myeloperoxidase0101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0303
Endonuclease III-like protein 10101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
NPYLR7B0011
Beta-1 adrenergic receptor 0012
beta-2 adrenergic receptor1001
serine/threonine-protein kinase mTOR isoform 11001
Beta-2 adrenergic receptor0225
Beta-2 adrenergic receptor0011
Alpha-2B adrenergic receptor0202
D(4) dopamine receptor0101
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Vasopressin V1a receptor0112
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0011
Alpha-1B adrenergic receptor0011
Glutamate receptor ionotropic, NMDA 1 1013
D(1A) dopamine receptor1001
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380023
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310011
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600011
Oxytocin receptor0112
Glutamate receptor ionotropic, NMDA 2A 0012
Glutamate receptor ionotropic, NMDA 2B0012
Glutamate receptor ionotropic, NMDA 2C0012
Beta-2 adrenergic receptor 0112
Glutamate receptor ionotropic, NMDA 2D0012
Taste receptor type 2 member 420011
Beta-2 adrenergic receptor0022
Glutamate receptor ionotropic, NMDA 3B0012
Taste receptor type 2 member 160011
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 100011
Taste receptor type 2 member 90011
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40011
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Glutamate receptor ionotropic, NMDA 3A0012
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
GTP-binding nuclear protein Ran isoform 11001
Cytochrome P450 1A10202
Leukotriene B4 receptor 10202
Leukotriene B4 receptor 20101
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
Phospholipase A-2-activating protein0101
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosinase0101
Carbonic anhydrase0102
Large neutral amino acids transporter small subunit 10202
SLC16A10 protein0001
Carbonic anhydrase 0102
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0102
Monocarboxylate transporter 100001
Carbonic anhydrase 130102
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Progesterone receptor06411
PINK12002
Parkin4004
Mineralocorticoid receptor 0314
Androgen receptor0426
Androgen receptor0011
Histamine H2 receptor0202
Aldo-keto reductase family 1 member C2 0202
Guanine nucleotide-binding protein G4004
Aldo-keto reductase family 1 member C10202
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70001
Cannabinoid receptor 10202
nuclear factor NF-kappa-B p105 subunit isoform 11001
Nuclear receptor subfamily 1 group I member 20011
glucocerebrosidase2002
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0505
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0202
Matrix metalloproteinase-90101
Protein mono-ADP-ribosyltransferase PARP150101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
DNA gyrase subunit B0101
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0314
Potassium voltage-gated channel subfamily E member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0101
Zinc finger protein mex-50001
5-hydroxytryptamine receptor 70202
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Hormone-sensitive lipase0101
Aldo-keto reductase family 1 member C40101
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Estrogen receptor0022
Estrogen receptor beta0022
Proton-coupled amino acid transporter 10101
STE240001
CAAX prenyl protease0001
Trypsin0001
Solute carrier family 2, facilitated glucose transporter member 90112
Nrf21001
Microphthalmia-associated transcription factor0001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
caspase recruitment domain family, member 150101
Caspase-72002
glucose-6-phosphate 1-dehydrogenase isoform b0101
caspase-32002
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
ras-related protein Rab-9A2002
Beta lactamase (plasmid)0101
Valosin-containing protein0101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
eukaryotic translation initiation factor 4E isoform 10101
Serum paraoxonase/arylesterase 10101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Beta-lactamase 0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Estrogen receptor 10101
D(1A) dopamine receptor1001
fMet-Leu-Phe receptor0101
Cyclooxygenase-2 0101
huntingtin isoform 21001
luciferase0001
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
UDP-glucuronosyltransferase 1A90101
Transient receptor potential cation channel subfamily A member 10011
UDP-glucuronosyltransferase 1-60101
Solute carrier family 22 member 10101
Canalicular multispecific organic anion transporter 10101
Pannexin-10101
Solute carrier family 22 member 120101
UDP-glucuronosyltransferase 1A70101
Pannexin-10101
Solute carrier family 22 member 20101
NS5 0011
Thrombopoietin1001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
glycogen synthase kinase-3 beta isoform 10011
Transmembrane protease serine 20011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Adenosylhomocysteinase0002
Adenosine receptor A10101
Genome polyprotein0011
Angiotensin-converting enzyme 2 0011
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0202
Arylacetamide deacetylase0102
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
DNA-directed RNA polymerase subunit beta0101
B-cell lymphoma 6 protein0011
DNA-directed RNA polymerase subunit beta0101
Insulin-degrading enzyme0101
DNA repair protein RAD52 homolog0101
Metallo-beta-lactamase type 20101
Angiotensin-converting enzyme0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
Dihydrofolate reductase0304
Endothelin-1 receptor0101
Protease 0112
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Carbonic anhydrase 20112
Carbonic anhydrase 5A, mitochondrial0101
Delta-type opioid receptor0101
Delta-type opioid receptor0101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 40101
Protein argonaute-20011
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
P2Y purinoceptor 120101
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Urease0203
Urease subunit alpha0101
D(3) dopamine receptor0101
Urease subunit alpha0101
Urease subunit beta0101
Urease subunit beta 0101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Thymidine kinase 0102
Thymidine kinase, cytosolic0204
Thymidine kinase0102
Thymidylate synthase0001
Thymidine phosphorylase0001
Thymidine phosphorylase0001
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidine kinase0001
Thymidylate kinase0101
Thymidine kinase 0102
Sterol O-acyltransferase 10101
Thymidine kinase0001
Thymidine kinase0001
procathepsin L isoform 1 preproprotein0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Dihydrofolate reductase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Metabotropic glutamate receptor 50101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
P2Y purinoceptor 40011
N-acetyllactosaminide alpha-1,3-galactosyltransferase0101
P2Y purinoceptor 2 0112
P2Y purinoceptor 20011
P2Y purinoceptor 40011
RNA-directed RNA polymerase 0001
Chain A, Arginase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]