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bile acid

Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.

ChEBI ID: 3098

Members (17)

MemberDefinitionRole
12-ketolithocholic acid12-ketolithocholic acid
3,7,12-trihydroxycholest-24-enoic acid3alpha,7alpha,12alpha-Trihydroxy-5beta-24E-cholesten-26-oic acid
7-ketolithocholic acidA bile acid that is lithocholic acid carrying an additional oxo substituent at position 7.7-oxolithocholic acid
antcin kantcin K
chenodeoxycholic acidA dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively.chenodeoxycholic acid
cholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.cholic acid
dehydroeburicoic acidDehydroeburicoic acid
deoxycholic acidA bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively.deoxycholic acid
hyodeoxycholic acidA member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6.hyodeoxycholic acid
lithocholic acidA monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.lithocholic acid
methyl cholateCholic Acid Methyl Ester
msi 1436trodusquemine
muricholic acidA group of trihydroxy-5beta-cholanic acids that are the 6,7-diastereoisomers of 3alpha,6,7-trihydroxy-5beta-cholan-24-oic acid.muricholic acids
norcholateNorcholic acid
squalamineSqualamine
ursocholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three hydroxy substituents at positions 3alpha, 7beta and 12alpha.ursocholic acid
ursodeoxycholic acidA bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones.ursodeoxycholic acid

Research

Studies (13,021)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19904,291 (32.95)18.7374
1990's2,207 (16.95)18.2507
2000's2,326 (17.86)29.6817
2010's3,089 (23.72)24.3611
2020's1,108 (8.51)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,096 (6.57%)5.53%
Reviews1,423 (8.53%)6.00%
Case Studies795 (4.77%)4.05%
Observational42 (0.25%)0.25%
Other13,326 (79.88%)84.16%