Any hydroxy monocarboxylic acid carrying at least two hydroxy groups.
| Member | Definition | Role |
|---|
| (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | A dihydroxy monocarboxylic acid that is N-isopropylindole which is substituted at position 3 by a p-fluorophenyl group and at position 2 by a 6-carboxy-3,5-dihydroxyhex-1-en-1-yl group. It has four possible diastereoisomers. | (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid |
| 1,4-dihydroxy-2-naphthoic acid | A naphthoic acid that is 2-naphthoic acid substituted by hydroxy groups at positions 1 and 4. | 1,4-dihydroxy-2-naphthoic acid |
| 23-hydroxyursolic acid | A pentacyclic triterpenoid that is ursolic acid substituted by an additional hydroxy group at position 23. It has been isolated from Lagerstroemia speciosa and Juglans sinensis. | 23-hydroxyursolic acid |
| 2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid | A pentacyclic triterpenoid that is betulinic acid carrying an additional alpha-hydroxy group at position 2. It has been isolated from Breynia fruticosa. | 2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid |
| 3-(3-hydroxyphenyl)-3-hydroxypropanoic acid | A dihydroxy monocarboxylic acid that is 3-hydroxypropanoic acid substituted by a 3-hydroxyphenyl group at position 3. | 3-(3-hydroxyphenyl)-3-hydroxypropanoic acid |
| 5,12-dihydroxy-6,8,14-eicosatrienoic acid | A leukotriene obtained by formal dehydrogenation of the 10,11-double bond in leukotriene B4. | 10,11-dihydroleukotriene B4 |
| 9,10-dihydroxystearic acid | A hydroxy-fatty acid formally derived from octacecanoic (stearic) acid by hydroxy substitution at positions 9 and 10. | 9,10-dihydroxyoctadecanoic acid |
| alpha,beta-dihydroxyisovaleric acid | A dihydroxy monocarboxylic acid that is isovaleric acid which is substituted by hydroxy groups at positions 2 and 3. | 2,3-dihydroxy-3-methylbutanoic acid |
| atorvastatin | A dihydroxy monocarboxylic acid that is a member of the drug class known as statins, used primarily for lowering blood cholesterol and for preventing cardiovascular diseases. | atorvastatin |
| atractyligenine | A diterpenoid isolated from coffee silverskin. It inhibits cutaneous photoaging. | atractyligenin |
| cerivastatin | (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. | cerivastatin |
| epi-maslinic acid | A pentacyclic triterpenoid that is 3alpha-hydroxy epimer of maslinic acid. Isolated from Prunella vulgaris and Isodon japonicus, it exhibits anti-inflammatory activity. | epi-maslinic acid |
| hederagenin | A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). | hederagenin |
| l 154819 | A polyketide obtained by hydrolysis of the pyranone ring of lovastatin. | mevinolinic acid |
| leukotriene b4 | A leukotriene composed of (6Z,8E,10E,14Z)-icosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. It is a lipid mediator of inflammation that is generated from arachidonic acid via the 5-lipoxygenase pathway. | leukotriene B4 |
| leukotriene b5 | A leukotriene composed of (6Z,8E,10E,14Z,17Z)-icosapentaenoic acid carrying (5S)- and (12R)-hydroxy substituents. | leukotriene B5 |
| maslinic acid | A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. | maslinic acid |
| pitavastatin | A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise. | pitavastatin |
| rosuvastatin | A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer). | rosuvastatin |