tetracycline and Intestinal-Diseases

Topics: Africa, Western; Animals; Bicarbonates; Child; Chlorides; Cholera; Diarrhea; Dogs; Enterotoxins; Europe; Feces; Glucose; Humans; Intestinal Absorption; Intestinal Diseases; Intestinal Mucosa; Isotonic Solutions; Potassium; Sodium; Tetracycline; Water-Electrolyte Balance

A prospective randomized trial was performed to determine the value of tetracycline lavage in addition to systemic antibiotic prophylaxis in 159 patients undergoing elective and emergency intestinal operations. Tetracycline lavage was associated with a significant overall reduction in postoperative infection rates in 25 of 74 patients (34 percent) receiving saline lavage compared with 15 of 85 patients (18 percent) having tetracycline lavage (P less than 0.05). Tetracycline lavage was associated with a significant reduction in the counts of aerobic and anaerobic bacteria in the peritoneal fluid at the end of the operation (P less than 0.05 and P less than 0.01, respectively) and with a significant reduction of aerobes 24 hours postoperatively (P less than 0.02). Tetracycline lavage would appear to confer clinical benefit in preventing postoperative infection.

Topics: Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Colonic Diseases; Female; Humans; Intestinal Diseases; Male; Middle Aged; Prospective Studies; Random Allocation; Sodium Chloride; Surgical Wound Infection; Tetracycline; Therapeutic Irrigation

Helicobacter pylori resistance to antimicrobial agents is an important factor compromising the efficacy of treatment. Therefore the aims of our study were: to determine the prevalence of H. pylori resistance to clarithromycin, metronidazole, amoxycillin and tetracycline in children prior to eradication therapy, to compare different methods of susceptibility testing and to detect mutations responsible for clarithromycin resistance. During 1996-2000, 259 H. pylori strains were isolated from antral gastric biopsies. Susceptibility to antimicrobials was determined by the agar dilution method and the Etest. Mutations in the 23S rRNA gene associated with clarithromycin resistance were analysed by PCR-RFLP and direct sequencing. Overall, ninety-six strains (37%) were resistant to metronidazole, 50 strains (19.3%) were resistant to clarithromycin, and 20 strains (7.7%) were simultaneously resistant to both drugs. All cultured isolates were sensitive to amoxycillin and only one isolate (0.4%) was resistant to tetracycline. The agar dilution method and the Etest showed a perfect category correlation for clarithromycin and 4% discrepancies for metronidazole. Primary resistance to clarithromycin was mainly associated with an A2143G mutation in the 23S rRNA gene of H. pylori. The study highlights the high prevalence of H. pylori primary resistance to clarithromycin in Polish children, which implies a need for pretreatment susceptibility testing.

Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Child; Clarithromycin; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Helicobacter Infections; Helicobacter pylori; Humans; Intestinal Diseases; Metronidazole; Poland; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 23S; Sequence Analysis, DNA; Tetracycline

A 48-year-old woman, who had undergone reversal of a jejunal loop, presented with skin eruptions, myalgia and arthralgia. Delayed gastric emptying was associated with a gastric phytobezoar. The clinicopathological features and response to therapy were typical of the dermatosis-arthritis syndrome, and probably were related to bacterial overgrowth.

Topics: Anastomosis, Roux-en-Y; Arthritis; Bacterial Infections; Bezoars; Candidiasis; Combined Modality Therapy; Dermatitis; Female; Gastrointestinal Contents; Humans; Intestinal Diseases; Jejunum; Lactobacillus; Middle Aged; Stomach; Streptococcal Infections; Syndrome; Tetracycline

Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Administration Schedule; Fosfomycin; Humans; Intestinal Diseases; Intestinal Mucosa; Penicillins; Tetracycline

Topics: Adult; Diverticulum; Duodenal Diseases; Ehlers-Danlos Syndrome; Humans; Intestinal Diseases; Male; Tetracycline

Sensitivity of Shigella, pathogenic Escherichia, Proteus and Staphylococcus isolated from children with acute intestinal diseases was studied with respect to antibiotics widely used in medical practice: streptomycin, levomycetin, tetracycline, chlortetracycline, oxytetracycline and neomycin. The antibiotic sensitivity was determined with the method of indicator discs. It was found that sensitivity of shigella was: 44 percent to streptomycin, 69.5 per cent to levomycetin, 18.5 per cent to tetracycline, 18.5 per cent to chlortetracycline, 23 per cent to oxytetracycline and 94 per cent to neomycin. Sensitivity of pathogenic Eschericia was 28, 33, 14, 14, 25 and 74 per cent, sensitivity of staphylococci was 46, 56.5, 21, 21, 31.5 and 89.5 per cent, sensitivity of Proteus was 15, 31.5, 3.5, 3.5, 7.5 and 52.5 per cent respectively. Cross resistance with respect to tetracyclines was found in all the microbes studie. Intragenera differences in the antibiotic sensitivity were observed among Shigella and pathogenic Escherichia.

Topics: Acute Disease; Anti-Bacterial Agents; Child; Chloramphenicol; Chlortetracycline; Drug Resistance, Microbial; Escherichia; Georgia (Republic); Humans; Intestinal Diseases; Microbial Sensitivity Tests; Neomycin; Oxytetracycline; Proteus; Shigella; Species Specificity; Staphylococcus; Streptomycin; Tetracycline

Topics: Bacteroides; Bacteroides Infections; Clindamycin; Culture Media; Drug Evaluation; Drug Resistance, Microbial; Drug Synergism; Humans; Intestinal Diseases; Lincomycin; Metronidazole; Rifampin; Surgical Wound Infection; Tetracycline

Topics: Anti-Infective Agents; Asthma; Bronchiectasis; Bronchitis; Bronchopneumonia; Chloramphenicol; Drug Combinations; Enteritis; Folic Acid Antagonists; Humans; Intestinal Diseases; Lung Diseases; Microbial Sensitivity Tests; Pneumonia; Pyrimidines; Respiratory Tract Infections; Sulfamethoxazole; Tetracycline; Trimethoprim

Topics: Actinomycosis; Adolescent; Cecal Diseases; Humans; Hydrazines; Ileum; Intestinal Diseases; Male; Mycetoma; Postoperative Care; Streptomycin; Tetracycline

Topics: Adolescent; Adult; Appendicitis; Arthritis; Child; Child, Preschool; Chloramphenicol; Diagnosis, Differential; Drug Resistance, Microbial; Erythema Nodosum; Female; Humans; Intestinal Diseases; Male; Pasteurella; Pasteurella Infections; Sepsis; Serologic Tests; Tetracycline

A review of the literature on subclinical intestinal disease shows its probable relevance in certain nutritional deficiencies in the indigenous residents of tropical climates. A significant incidence of intestinal disease has been defined among asymptomatic fit-looking adult Nigerians. The results of subsequent investigation into the pathogenesis of this disorder strongly point to hypoalbuminaemia as the important factor capable of producing a biochemically and histologically defined malabsorptive state leading to subnormal nutritional status among members of this community.

Topics: Adult; Anemia; Biopsy; Ecology; Folic Acid; Humans; Intestinal Diseases; Intestinal Diseases, Parasitic; Intestines; Malabsorption Syndromes; Niger; Proteins; Serum Albumin; Serum Globulins; Sprue, Tropical; Strongyloidiasis; Tetracycline; Tropical Medicine; Xylose

Topics: 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Anti-Bacterial Agents; Betamethasone; Dermatitis; Fludrocortisone; Humans; Hydrocortisone; Intestinal Diseases; Intestine, Small; Ointments; Prednisolone; Psoriasis; Skin Diseases; Tetracycline

Topics: Anti-Bacterial Agents; Biological Products; Drug Industry; Dust; Environmental Exposure; Escherichia coli; Humans; Intestinal Diseases; Intestines; Occupational Diseases; Penicillin Resistance; Penicillins; Streptomycin; Tetracycline; USSR

Topics: Adult; Biological Products; Candida; Chemical Industry; Endopeptidases; Environmental Exposure; Escherichia coli; Feces; Humans; Intestinal Diseases; Lactobacillus; Middle Aged; Occupational Diseases; Riboflavin; Staphylococcus; Tetracycline; Thiamine; Vitamin B Deficiency

Topics: Anemia, Macrocytic; Celiac Disease; Diverticulum; Duodenum; Humans; Intestinal Diseases; Jejunum; Male; Middle Aged; Spinal Cord Diseases; Tetracycline; Vitamin B 12

Microbial populations of the small bowel and bile salt metabolism were studied in 15 patients with lesions of the stomach and small intestine. These types of microorganism could be correlated with the site and extent of stasis in the small bowel and the presence of a normally functioning stomach. The presence of obligate anaerobes (bacteroides) and free bile acids could be correlated with areas of stagnation. When these abnormalities were detected throughout the small bowel, steatorrhoea was also noted. However, bacteroides and free bile acids in localized regions of either proximal or distal small bowel were generally associated with normal faecal fat excretion. Vitamin B(12) malabsorption appeared to be related to the total number of bacteria colonizing the small bowel rather than to any specific type of microorganisms. The effect of antibiotics on intestinal function and bacteriology was studied in three patients. In one patient, the broad-spectrum antibiotic tetracycline was effective in eradicating an abnormal bacterial flora. In the other two, lincomycin, which is specifically effective in eradicating the anaerobic flora, restored intestinal function to normal.

Topics: Adult; Aged; Bacteria; Bacteroides; Bile Acids and Salts; Celiac Disease; Diverticulum; Fats; Feces; Female; Gastrectomy; Humans; Intestinal Absorption; Intestinal Diseases; Intestine, Small; Lincomycin; Lipids; Male; Middle Aged; Stomach Diseases; Tetracycline; Vitamin B 12

Topics: Female; Genital Diseases, Female; Humans; Intestinal Diseases; Latex Fixation Tests; Mycoplasma; Mycoplasma Infections; Respiratory Tract Infections; Tetracycline; Urinary Tract Infections

Topics: Adult; Aged; Bile Acids and Salts; Biopsy; Celiac Disease; Child; Duodenum; Fatty Acids; Female; Humans; Ileum; Intestinal Diseases; Intestinal Mucosa; Jejunum; Male; Microscopy, Electron; Middle Aged; Tetracycline

Topics: Adolescent; Agammaglobulinemia; Diarrhea; Giardiasis; Humans; Hyperplasia; Infusions, Parenteral; Intestinal Diseases; Intestine, Small; Jejunum; Lymphatic Diseases; Lymphatic System; Male; Plasma; Quinacrine; Radiography; Tetracycline

Topics: Adult; Celiac Disease; Chloramphenicol; Female; Humans; Intestinal Diseases; Intestinal Obstruction; Intestine, Small; Jejunum; Malabsorption Syndromes; Middle Aged; Pneumatosis Cystoides Intestinalis; Pneumoperitoneum; Radiography; Scleroderma, Systemic; Tetracycline; Vitamin B 12; Xylose

Topics: Anti-Bacterial Agents; Arteriosclerosis; Cardiac Surgical Procedures; Cross Infection; Humans; Intestinal Diseases; Lung Diseases; Postoperative Complications; Staphylococcal Infections; Streptomycin; Surgical Wound Infection; Tetracycline; Vascular Surgical Procedures

Topics: Anti-Bacterial Agents; Candidiasis; Chloramphenicol; Gastrointestinal Diseases; Humans; Intestinal Diseases; Stomach; Tetracycline; Toxicology

Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Celiac Disease; Diverticulum; Drug Therapy; Geriatrics; Humans; Intestinal Diseases; Intestine, Small; Intestines; Pain; Steatorrhea; Tetracycline; Toxicology; Vitamin B 12

Topics: Celiac Disease; Diarrhea; Diverticulum; Duodenal Diseases; Escherichia coli Infections; Humans; Intestinal Diseases; Intestines; Sprue, Tropical; Steatorrhea; Tetracycline; Vitamin B 12

Topics: Anti-Bacterial Agents; Intestinal Diseases; Liver Diseases; Lymphadenitis; Mice; Pathology; Pharmacology; Protein Synthesis Inhibitors; Research; Spleen; Tetracycline; Toxicology

Topics: Anti-Bacterial Agents; Disease; Intestinal Diseases; Intestines; Staphylococcal Infections; Tetracycline

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Disease; Intestinal Diseases; Intestines; Oleandomycin; Protein Synthesis Inhibitors; Tetracycline

Topics: Anti-Bacterial Agents; Disease; Intestinal Diseases; Intestines; Intraabdominal Infections; Protein Synthesis Inhibitors; Tetracycline