Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
| Member | Definition | Class |
|---|
| adenosine monophosphate | A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. | adenosine 5'-monophosphate |
| alpha-linolenic acid | A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. | alpha-linolenic acid |
| arginine | An L-alpha-amino acid that is the L-isomer of arginine. | L-arginine |
| arsenic | | arsenic atom |
| asparagine | An optically active form of asparagine having L-configuration. | L-asparagine zwitterion; L-asparagine |
| aspartame | A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. | aspartame zwitterion; aspartame |
| boron | | boron atom |
| chromium | A chromium group element atom that has atomic number 24. | chromium atom |
| citrulline | The L-enantiomer of citrulline. | L-citrulline zwitterion; L-citrulline |
| cobalt | A cobalt group element atom that has atomic number 27. | cobalt atom |
| d-alpha tocopherol | An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. | (R,R,R)-alpha-tocopherol |
| eicosapentaenoic acid | An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. | all-cis-5,8,11,14,17-icosapentaenoic acid |
| glutamic acid | An optically active form of glutamic acid having L-configuration. | L-glutamic acid |
| glutamine | An optically active form of glutamine having L-configuration. | L-glutamine zwitterion; L-glutamine |
| glycine | The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. | glycine zwitterion; glycine |
| histidine | The L-enantiomer of the amino acid histidine. | L-histidine zwitterion; L-histidine |
| lysine | An L-alpha-amino acid; the L-isomer of lysine. | L-Lysine zwitterion; L-lysine |
| manganese | | manganese atom; manganese(0) |
| methionine | The L-enantiomer of methionine. | L-methionine zwitterion; L-methionine |
| molybdenum | | molybdenum atom |
| nickel | Chemical element (nickel group element atom) with atomic number 28. | nickel atom |
| phenylalanine | The L-enantiomer of phenylalanine. | L-phenylalanine zwitterion; L-phenylalanine |
| proline | Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. | L-proline zwitterion; L-proline |
| s-adenosylmethionine | A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine |
| selenium | | selenium atom |
| succinic acid | An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. | succinic acid |
| threonine | An optically active form of threonine having L-configuration. | L-threonine zwitterion; L-threonine |
| tin | | tin atom; tin(0) |
| tryptophan | The L-enantiomer of tryptophan. | L-tryptophan zwitterion; L-tryptophan |
| tungsten | | tungsten |
| tyrosine | An optically active form of tyrosine having L-configuration. | L-tyrosine zwitterion; L-tyrosine |
| valine | The L-enantiomer of valine. | L-valine zwitterion; L-valine |
| vanadium | | vanadium atom; vanadium(0) |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 2 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 19.9683 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 0.7762 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 34.3140 | 2 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 18.9365 | 1 | 4 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 18.9995 | 7 | 16 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 28.1538 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 6.9252 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 6.5104 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 14.5859 | 2 | 5 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 28.0107 | 2 | 5 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 27.8280 | 2 | 6 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.7877 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 20.7945 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 22.4113 | 2 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 19.1180 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 14.0025 | 2 | 5 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 6.9622 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 8.3216 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 23.3086 | 1 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 43.5766 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 26.6086 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 15.9387 | 2 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 11.8966 | 2 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 12.9244 | 2 | 5 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 29.0085 | 6 | 13 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 67.9623 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 18.3276 | 5 | 8 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 13.1202 | 1 | 12 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 30.5658 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 54.3693 | 3 | 3 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 4.1538 | 1 | 4 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 8.3216 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 2.4202 | 1 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 29.4130 | 2 | 6 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 9.2000 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 18.0332 | 2 | 8 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 26.9597 | 3 | 6 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 1.4581 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 27.0741 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 14.1254 | 1 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 24.9054 | 1 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 51.1231 | 1 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 61.6524 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 63.6750 | 2 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 11.6993 | 2 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 6.4937 | 1 | 2 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 58.6262 | 2 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 25.7246 | 2 | 7 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.3981 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.2512 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 44.2296 | 4 | 6 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 25.3207 | 1 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 16.8055 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 4.5479 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 30.0920 | 5 | 10 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 41.8803 | 5 | 5 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 70.1521 | 1 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 65.9626 | 2 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 60.5715 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 2.3016 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 4.7163 | 1 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 43.5853 | 3 | 7 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 16.2776 | 2 | 3 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 16.8336 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 49.2971 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 49.2971 | 2 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 63.6750 | 2 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 26.3232 | 2 | 4 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 24.8033 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 25.8150 | 2 | 7 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 55.3702 | 2 | 5 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.0158 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 9.8925 | 3 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 47.4417 | 1 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 33.7805 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 51.1020 | 2 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 35.8877 | 1 | 4 |
| WRN | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 6,300.0000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 40.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | IC50 | 80.2000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 80.0000 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Ki | 580.0000 | 1 | 1 |
| Alcohol dehydrogenase E chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Alcohol dehydrogenase S chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 77.5250 | 3 | 4 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Bos taurus (cattle) | IC50 | 80.2033 | 3 | 3 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.4400 | 1 | 1 |
| Amino acid transporter | Rattus norvegicus (Norway rat) | IC50 | 1,486.1222 | 6 | 9 |
| Angiotensin-converting enzyme | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 48.7000 | 1 | 2 |
| Asc-type amino acid transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 300.0000 | 1 | 1 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | Escherichia coli K-12 | Ki | 38,000.0000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Cationic amino acid transporter 3 | Homo sapiens (human) | IC50 | 220.5000 | 1 | 2 |
| Chain A, ADP-dependent glucokinase | Pyrococcus furiosus | Ki | 60.0000 | 1 | 1 |
| Chain A, Aminopeptidase | Streptomyces griseus | Ki | 11,366.6667 | 1 | 3 |
| Chain A, Arginase 1 | Rattus norvegicus (Norway rat) | Ki | 3,600.0000 | 1 | 1 |
| Chain A, CHORISMATE MUTASE | Saccharomyces cerevisiae (brewer's yeast) | Ki | 50.0000 | 1 | 1 |
| Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | Escherichia coli | Ki | 15.0000 | 1 | 1 |
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 2 |
| Chain A, Methionine aminopeptidase | Pyrococcus furiosus | Ki | 150,000.0000 | 1 | 1 |
| Chain A, phosphodiesterase-nucleotide pyrophosphatase | Xanthomonas citri pv. citri str. 306 | Ki | 260.0000 | 1 | 1 |
| Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta)) | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Chain A, Ribonuclease pancreatic | Bos taurus (cattle) | Ki | 46.0000 | 1 | 2 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | Pisum sativum (garden pea) | Ki | 36,600.0000 | 1 | 2 |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 1 |
| Choline O-acetyltransferase | Homo sapiens (human) | IC50 | 1,800,000,000.0000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 54.0000 | 1 | 2 |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | IC50 | 15.3000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 7.6320 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 2.6000 | 1 | 1 |
| Delta-aminolevulinic acid dehydratase | Escherichia coli K-12 | Ki | 12,500.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 6,500.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 2,800.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 80.2000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | IC50 | 3,362.7667 | 3 | 3 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | IC50 | 76.4503 | 4 | 6 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Ki | 33.3114 | 1 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | IC50 | 65.9784 | 2 | 4 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Ki | 62.5478 | 1 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | IC50 | 41.1195 | 2 | 4 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Ki | 25.0848 | 1 | 2 |
| Excitatory amino acid transporter 4 | Rattus norvegicus (Norway rat) | IC50 | 12.6930 | 2 | 4 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 150,000.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 0.3900 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.6436 | 11 | 11 |
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | IC50 | 1.3000 | 2 | 2 |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | IC50 | 428.0000 | 2 | 2 |
| Glutamate receptor 1 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 1.3607 | 3 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6345 | 2 | 2 |
| Glutamate receptor 2 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 0.9400 | 3 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.4452 | 4 | 5 |
| Glutamate receptor 3 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Ki | 2.3122 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 0.8680 | 3 | 3 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.7270 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | Ki | 0.7010 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Ki | 0.1284 | 5 | 7 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | Ki | 1.1060 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Ki | 0.9566 | 7 | 9 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | Ki | 0.7890 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 0.4201 | 4 | 6 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | Ki | 0.7337 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 42.2039 | 9 | 10 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 4,400.0000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 57.4500 | 1 | 2 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 48.6500 | 1 | 2 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Glycine--tRNA ligase | Bombyx mori (domestic silkworm) | Ki | 80.0000 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 498.7000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase | Escherichia coli K-12 | Ki | 450.0000 | 1 | 1 |
| Intestinal-type alkaline phosphatase | Bos taurus (cattle) | IC50 | 80.2060 | 5 | 5 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 47.5500 | 3 | 4 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 115.8182 | 3 | 11 |
| Large neutral amino acids transporter small subunit 1 | Rattus norvegicus (Norway rat) | Ki | 55.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 710.0000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 3.6067 | 3 | 3 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.3400 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 7.6500 | 4 | 4 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Ki | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 5.6000 | 4 | 4 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 4.3167 | 3 | 3 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Ki | 38.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Ki | 5,400.0000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | IC50 | 0.0057 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 2.2500 | 1 | 1 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | Homo sapiens (human) | Ki | 5,000.0000 | 1 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Neutral amino acid transporter A | Homo sapiens (human) | IC50 | 2,056.0000 | 1 | 3 |
| Neutral amino acid transporter B(0) | Homo sapiens (human) | IC50 | 3,738.3333 | 1 | 3 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Ki | 2,350.0000 | 1 | 2 |
| Oxoeicosanoid receptor 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| phospholipase A2 precursor | Homo sapiens (human) | IC50 | 22.3000 | 1 | 1 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 1,000.0000 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 4.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 53.0000 | 1 | 2 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 9.5500 | 1 | 2 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.0002 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 3,350.0000 | 1 | 2 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 7.6320 | 1 | 1 |
| S-ribosylhomocysteine lyase | Bacillus subtilis subsp. subtilis str. 168 | Ki | 61.0000 | 1 | 1 |
| Serine racemase | Homo sapiens (human) | Ki | 366.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 2,238.7200 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 1,348.9600 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 68.8000 | 2 | 2 |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Solute carrier family 13 member 3 | Homo sapiens (human) | IC50 | 107.0000 | 1 | 1 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 500.0000 | 1 | 3 |
| Tissue factor | Homo sapiens (human) | IC50 | 54.0000 | 1 | 2 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 70.0000 | 2 | 2 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 2 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Ki | 11,500.0000 | 1 | 1 |
| Tubulin--tyrosine ligase | Homo sapiens (human) | Ki | 25.0000 | 1 | 1 |
| Uracil nucleotide/cysteinyl leukotriene receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Mus musculus (house mouse) | Ki | 0.9786 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Burkholderia pseudomallei K96243 | Kd | 1,000.0000 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Kd | 5,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | EC50 | 3.7095 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 3.6500 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 0.5000 | 1 | 1 |
| Alpha-tocopherol transfer protein | Homo sapiens (human) | Kd | 2.4200 | 1 | 1 |
| Chain A, Aspartate Aminotransferase | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, Glutamine Binding Protein | Escherichia coli | Kd | 0.5000 | 1 | 1 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 101.8000 | 1 | 5 |
| Chain A, HISTIDINE-BINDING PROTEIN | Escherichia coli | Kd | 0.0640 | 1 | 1 |
| Chain A, Methionyl-tRNA synthetase | Escherichia coli | Kd | 11.0000 | 1 | 2 |
| Chain A, Protein (aspartate Aminotransferase) | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, Slr1257 protein | Synechocystis sp. PCC 6803 substr. Kazusa | Kd | 0.2400 | 1 | 1 |
| Chain A, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Chain A, TYROSYL-tRNA SYNTHETASE | Geobacillus stearothermophilus | Kd | 11.6000 | 1 | 1 |
| Chain B, Glycogen Phosphorylase B | Oryctolagus cuniculus (rabbit) | Kd | 85.3333 | 1 | 3 |
| Chain B, tryptophanyl-tRNA synthetase | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain C, Tryptophanyl-tRNA synthetase II | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | Salmonella enterica subsp. enterica serovar Typhimurium | Kd | 0.2570 | 1 | 6 |
| Chain K, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | Kd | 100.0000 | 2 | 2 |
| Free fatty acid receptor 1 | Homo sapiens (human) | EC50 | 5.0673 | 4 | 5 |
| Free fatty acid receptor 4 | Homo sapiens (human) | EC50 | 2.9180 | 2 | 2 |
| Glutamate receptor 1 | Homo sapiens (human) | EC50 | 792,445,056.0762 | 12 | 20 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 27.3799 | 6 | 7 |
| Glutamate receptor 2 | Homo sapiens (human) | EC50 | 722,116,393.1444 | 8 | 11 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 1,482,620,106.9400 | 4 | 5 |
| Glutamate receptor 3 | Homo sapiens (human) | EC50 | 2,264,128,594.8718 | 5 | 7 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 54.8048 | 5 | 6 |
| Glutamate receptor 4 | Homo sapiens (human) | EC50 | 9,952,675,009.4244 | 2 | 4 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 18.6392 | 4 | 5 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | EC50 | 57.3333 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | EC50 | 129.1633 | 2 | 3 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | EC50 | 25.0000 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | EC50 | 65.9615 | 2 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 0.8959 | 12 | 13 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 1.1223 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | EC50 | 0.4856 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | EC50 | 0.3196 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | EC50 | 0.1858 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 94.7496 | 1 | 2 |
| Histidine-binding periplasmic protein | Escherichia coli K-12 | Kd | 0.1140 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | Kd | 650.0000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | EC50 | 45.2375 | 4 | 4 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 13.1512 | 10 | 12 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 7.3849 | 12 | 13 |
| Metabotropic glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 8.7450 | 8 | 10 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | EC50 | 2.8572 | 5 | 5 |
| Metabotropic glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 1.6294 | 3 | 4 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 14.9333 | 3 | 3 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 6.3776 | 8 | 10 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | EC50 | 163.5500 | 4 | 4 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | EC50 | 6.4817 | 8 | 10 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | EC50 | 98.3000 | 3 | 3 |
| Metabotropic glutamate receptor 6 | Rattus norvegicus (Norway rat) | EC50 | 35.7000 | 5 | 5 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | EC50 | 625.2950 | 4 | 4 |
| Metabotropic glutamate receptor 7 | Rattus norvegicus (Norway rat) | EC50 | 800.0000 | 2 | 3 |
| Metabotropic glutamate receptor 8 | Mus musculus (house mouse) | EC50 | 0.0220 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | EC50 | 14.4933 | 3 | 3 |
| Methyl-accepting chemotaxis protein NahY | Pseudomonas putida | Kd | 82.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 245.0000 | 2 | 2 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Kd | 7.0000 | 2 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 1.2510 | 2 | 2 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0580 | 1 | 1 |
| P2Y purinoceptor 1 | Homo sapiens (human) | EC50 | 4.3500 | 1 | 2 |
| P2Y purinoceptor 1 | Meleagris gallopavo (turkey) | EC50 | 3.1500 | 1 | 2 |
| P2Y purinoceptor 11 | Homo sapiens (human) | EC50 | 17.2500 | 1 | 1 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 1.8925 | 1 | 2 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Kd | 2.0000 | 1 | 2 |
| Protease | Human immunodeficiency virus 1 | Kd | 0.0011 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 113.0000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | Km | 14.0000 | 1 | 1 |
| Adenosine deaminase-like protein | Homo sapiens (human) | Km | 32.8000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 3.6413 | 1 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 3.6413 | 1 | 6 |
| Adenylate cyclase type 5 | Homo sapiens (human) | Km | 15.6000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Km | 380.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Adenylate kinase isoenzyme 1 | Homo sapiens (human) | Km | 175.0000 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Km | 580.0000 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Km | 441.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 26.2250 | 1 | 4 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 49.5000 | 1 | 4 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 41.6000 | 1 | 4 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 86.0000 | 2 | 8 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 36.8250 | 1 | 4 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 23.3500 | 1 | 4 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Activity | 0.0300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 11.5713 | 17 | 53 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 22.2971 | 3 | 7 |
| Carbonic anhydrase 13 | Homo sapiens (human) | KA | 0.5650 | 1 | 2 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 8.2875 | 2 | 4 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ka | 8.0829 | 3 | 7 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 21.9750 | 1 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Activity | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | KA | 18.0170 | 20 | 62 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ka | 31.0364 | 4 | 11 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 39.0000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | KA | 25.3462 | 5 | 13 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 3.8514 | 3 | 7 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ka | 3.4591 | 3 | 7 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 14.1483 | 4 | 12 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 22.5100 | 3 | 7 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 20.1525 | 4 | 8 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 33.3871 | 1 | 7 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Activity | 25.0000 | 1 | 1 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Km | 8.5500 | 2 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Km | 21.0000 | 2 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Km | 17.4500 | 2 | 2 |
| Excitatory amino acid transporter 3 | Rattus norvegicus (Norway rat) | Ks | 5.1000 | 1 | 1 |
| General amino-acid permease GAP1 | Saccharomyces cerevisiae S288C | Km | 37.0000 | 1 | 1 |
| Glutamate 5-kinase | Escherichia coli K-12 | I0.5 | 2.5000 | 1 | 1 |
| Glutamate racemase | Enterococcus faecalis V583 | Km | 1,200.0000 | 1 | 1 |
| Glutamate racemase | Helicobacter pylori 26695 | Km | 5,176.6667 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| GTP:AMP phosphotransferase AK3, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Km | 15.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | Km | 12.6000 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Activity | 1.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Activity | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Activity | 12.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Activity | 20.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Activity | 5,400.0000 | 1 | 1 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 4,443.3333 | 1 | 3 |
| NADP-dependent malic enzyme, mitochondrial | Homo sapiens (human) | Activity | 2,100.0000 | 1 | 1 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Activity | 14.5000 | 1 | 1 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Km | 2.7000 | 1 | 1 |
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | Activity | 25.0000 | 1 | 1 |
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | Km | 1.1000 | 1 | 1 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Activity | 14.0000 | 1 | 1 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Km | 5.7000 | 2 | 2 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | Km | 9.5000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 3.0885 | 1 | 4 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 230.0000 | 2 | 2 |
| S-adenosylmethionine synthase isoform type-1 | Rattus norvegicus (Norway rat) | Km | 42.8000 | 2 | 2 |
| S-adenosylmethionine synthase isoform type-2 | Rattus norvegicus (Norway rat) | Km | 10.3000 | 2 | 2 |
| SLC16A10 protein | Homo sapiens (human) | Km | 609.6667 | 1 | 3 |
| Taste receptor type 2 member 14 | Homo sapiens (human) | Activity | 1,000.0000 | 1 | 1 |
| Tryprostatin B synthase | Aspergillus fumigatus Af293 | Km | 820.0000 | 1 | 1 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Km | 167.0000 | 1 | 1 |