A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
| Member | Definition | Class |
|---|
| 2-amino-n(6)-hydroxyadenine | A 2,6-diaminopurine that is the N(6)-hydroxy derivative of 2,6-diamino-3H-purine. | 2-amino-6-hydroxyaminopurine |
| 2-ethoxyethanol | A hydroxyether that is the ethyl ether derivative of ethylene glycol. | 2-ethoxyethanol |
| 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | A retinoid that consists of benzoic acid substituted at position 4 by a 2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl group. It is a synthetic retinoid that acts as a selective agonist for the retinoic acid receptors (RAR). | arotinoid acid |
| 6-aminonicotinamide | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 6-aminonicotinic acid with ammonia. An inhibitor of the NADP(+)-dependent enzyme, 6-phosphogluconate dehydrogenase, it interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as cisplatin, in killing cancer cells. | 6-aminonicotinamide |
| 6-n-hydroxylaminopurine | A member of the class of 6-aminopurinnes that is adenine in which one of the exocyclic amino hydrogens is replaced by a hydroxy group. | N(6)-hydroxyadenine |
| acetaldehyde | The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke. | acetaldehyde |
| agn 190299 | A thiochromane that is acetylene in which the hydrogens are replaced by 5-carboxypyridin-2-yl and 4,4-dimethylthiochroman-6-yl groups. It is the active form of the prodrug tazarotene. | tazarotenic acid |
| ammodendrine | A piperidine alkaloid that is piperidine substituted by a 1-acetyl-1,4,5,6-tetrahydropyridin-3-yl group at position 2 (the 2R-stereoisomer). | ammodendrine |
| anabasine | A pyridine alkaloid that is pyridine substituted by a piperidin-2-yl group at position 3. | anabasine |
| aspirin | A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. | acetylsalicylic acid |
| bms453 | A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. | BMS-453 |
| busulfan | A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. | busulfan |
| dibutyl phthalate | A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans. | dibutyl phthalate |
| diethyl phthalate | The diethyl ester of benzene-1,2-dicarboxylic acid. | diethyl phthalate |
| diethylene glycol monomethyl ether | A hydroxypolyether that is the monomethyl ether derivative of diethylene glycol. | 2-(2-methoxyethoxy)ethanol |
| diisobutyl phthalate | A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of isobutanol. | diisobutyl phthalate |
| dimazine | A member of the class of hydrazines that is hydrazine substituted by two methyl groups at position 1. | 1,1-dimethylhydrazine |
| dipropylacetamide | A fatty amide derived from valproic acid. | valpromide |
| ethyl methanesulfonate | A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol. | ethyl methanesulfonate |
| evans blue | An organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence. | Evans blue |
| flubendazole | A member of the class of mebendazole in which the benzoyl group is replaced by a p-fluorobenzoyl group. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections. | flubendazole |
| gdc 0449 | A benzamide obtained by formal condensation between the carboxy group of 2-chloro-4-(methylsulfonyl)benzoic acid and the anilino group of 4-chloro-3-(pyridin-2-yl)aniline. Used for the treatment metastatic basal cell carcinoma. | vismodegib |
| hadacidin | A monocarboxylic acid that is N-hydroxyglycine in which the hydrogen attached to the nitrogen is replaced by a formyl group. It was originally isolated from cultures of Penicillium frequentans. | hadacidin |
| hydroxyurea | A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. | hydroxyurea |
| isotretinoin | A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases. | isotretinoin |
| l 154819 | A polyketide obtained by hydrolysis of the pyranone ring of lovastatin. | mevinolinic acid |
| malachite green | An organic chloride salt that is the monochloride salt of malachite green cation. Used as a green-coloured dye, as a counter-stain in histology, and for its anti-fungal properties in aquaculture. | malachite green |
| methylnitrosourea | A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups. | N-methyl-N-nitrosourea |
| nicotine | A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. | (S)-nicotine |
| ochratoxin a | A phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid (ochratoxin alpha). It is among the most widely occurring food-contaminating mycotoxins, produced by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium verrucosum. | ochratoxin A |
| peptide elongation factor 2 | A 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione that has S-configuration at the chiral centre. | (S)-thalidomide |
| phenytoin | A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5. | phenytoin |
| s 53482 | A benzoxazine that is N-(prop-2-yn-1-yl)-2H-1,4-benzoxazin-3(4H)-one which is substituted at position 6 by a 1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl group and at position 7 by a fluorine. A protoporphyrinogen oxidase inhibitor, it is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops. | flumioxazin |
| solasodine | An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills. | solasodine |
| soraphen a | A macrolide and an agent highly effective against plant-pathogenic fungi. It was extensively researched for agricultural use until it was discovered to be a teratogen. | soraphen A |
| tazarotene | The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin. | tazarotene |
| valproic acid | A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. | valproic acid |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 31.7626 | 1 | 3 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 7.5060 | 2 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 35.1784 | 3 | 7 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 31.1718 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 34.7250 | 1 | 13 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 27.7170 | 2 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 39.8107 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 23.8105 | 10 | 43 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 52.8015 | 2 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 1.3034 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 29.5662 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 27.5207 | 1 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.7569 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 27.5207 | 1 | 3 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 8.4921 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 29.2337 | 2 | 10 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 69.6219 | 1 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 38.5242 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 47.9628 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 38.5242 | 1 | 2 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 47.9628 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 49.0644 | 3 | 13 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 26.2000 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 26.0419 | 1 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.3548 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 28.6437 | 1 | 3 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 39.9292 | 2 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 30.0162 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 72.0513 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 5.2160 | 1 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 22.4824 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.9547 | 1 | 5 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 30.0162 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.2075 | 2 | 7 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 5.9622 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 20.3200 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 0.0126 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.1456 | 1 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 22.1892 | 1 | 8 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.1458 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 19.5147 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 55.4675 | 1 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 41.1771 | 1 | 2 |
| endonuclease IV | Escherichia coli | Potency | 8.9716 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.0105 | 12 | 63 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 32.6919 | 2 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 22.7510 | 8 | 51 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 12.6533 | 1 | 8 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 7.7696 | 4 | 18 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 37.4642 | 5 | 15 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 44.8780 | 1 | 2 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 13.5466 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 20.3200 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 8.6348 | 3 | 15 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 19.6704 | 3 | 18 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 29.3301 | 1 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 25.3389 | 1 | 3 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 15.9888 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 81.9892 | 5 | 14 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 11.9084 | 1 | 6 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 10.6101 | 1 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 52.1194 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 55.6302 | 2 | 6 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 39.8107 | 1 | 3 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 18.8336 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 73.3727 | 2 | 6 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 20.3200 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 50.1187 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 35.1687 | 2 | 8 |
| IDH1 | Homo sapiens (human) | Potency | 1.6299 | 1 | 3 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 20.3200 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 18.0396 | 1 | 6 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 9.0124 | 2 | 5 |
| interleukin 8 | Homo sapiens (human) | Potency | 68.0605 | 1 | 4 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 14.2008 | 2 | 6 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 29.4548 | 1 | 3 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 28.1838 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 43.1691 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 31.0990 | 2 | 4 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 3.4351 | 2 | 4 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 6.5812 | 2 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 8.1995 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 108.5175 | 4 | 20 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 45.3325 | 1 | 4 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 28.8527 | 1 | 4 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 12.8429 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 34.9139 | 3 | 23 |
| P53 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 4.5858 | 1 | 2 |
| Parkin | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 34.6833 | 2 | 3 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 2.8198 | 2 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 54.9978 | 1 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 83.7398 | 5 | 12 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 35.1231 | 5 | 15 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 4.9562 | 1 | 2 |
| polyprotein | Zika virus | Potency | 13.5466 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 32.9863 | 1 | 5 |
| PPM1D protein | Homo sapiens (human) | Potency | 1.4740 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 152.2778 | 2 | 14 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 531.7640 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 25.5086 | 2 | 6 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 50.2888 | 1 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 8.8457 | 2 | 15 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 6.7550 | 1 | 7 |
| relaxin receptor 1 isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 28.4478 | 3 | 30 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.1832 | 3 | 20 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 2.5832 | 1 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 17.3539 | 3 | 7 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 17.3539 | 3 | 7 |
| Smad3 | Homo sapiens (human) | Potency | 13.9353 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 18.4100 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 20.1044 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 14.5523 | 2 | 22 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 28.8561 | 4 | 20 |
| Thrombopoietin | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 22.9902 | 3 | 15 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 30.9379 | 4 | 8 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 26.0130 | 6 | 26 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 27.9556 | 2 | 4 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 17.1708 | 2 | 2 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 4.9562 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 4.9562 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 30.1964 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 34.6574 | 2 | 9 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 19.9528 | 4 | 8 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 53.1764 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 11.9084 | 1 | 6 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 0.0630 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 2.4000 | 1 | 2 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 155.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.8480 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.5400 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 161.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 0.0630 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | IC50 | 11.0000 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | IC50 | 4.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | Ki | 2.7000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Ki | 0.2236 | 7 | 8 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 5,000.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 4.1690 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 2.3570 | 1 | 1 |
| Adenylosuccinate synthetase isozyme 2 | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Bos taurus (cattle) | IC50 | 57.4000 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Homo sapiens (human) | IC50 | 50.1000 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Rattus norvegicus (Norway rat) | IC50 | 53.1000 | 2 | 2 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 56.1000 | 5 | 5 |
| Aldo-keto reductase family 1 member B7 | Rattus norvegicus (Norway rat) | IC50 | 56.1000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 4.1690 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.3570 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 4.1690 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.3570 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 6.6120 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 3.0190 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 367.4429 | 5 | 14 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 122.2857 | 2 | 7 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 2,710.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 7,530.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 1,160.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 1,844.0000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 113.0000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 31.0000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 23.0000 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | IC50 | 420.0000 | 1 | 1 |
| Cathepsin B | Mus musculus (house mouse) | IC50 | 230.0000 | 1 | 1 |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | IC50 | 0.9000 | 2 | 2 |
| Chain A, Epoxide hydrolase | Aspergillus niger | Ki | 250.0000 | 1 | 1 |
| Chain A, limonene-1,2-epoxide hydrolase | Rhodococcus erythropolis | Ki | 100.0000 | 1 | 1 |
| Cocaine esterase | Homo sapiens (human) | Ki | 7,900.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 2,060.0000 | 2 | 2 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Ki | 72.0000 | 1 | 1 |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | IC50 | 159.9560 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 210.6763 | 2 | 3 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 2,322.2000 | 4 | 4 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 8.0000 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 23.1500 | 2 | 2 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.4400 | 1 | 1 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.1100 | 1 | 1 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Homo sapiens (human) | IC50 | 0.9220 | 1 | 1 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Homo sapiens (human) | Ki | 0.8240 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 2,064.0000 | 2 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 108.6667 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Glutathione hydrolase 1 proenzyme | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 1,262.6014 | 7 | 7 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 4,117.5000 | 2 | 2 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 1,819.9480 | 5 | 5 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 1,846.1340 | 5 | 5 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 2,808.7500 | 4 | 4 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 2,808.7500 | 4 | 4 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 2,290.0020 | 5 | 5 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 3,411.6667 | 3 | 3 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 2,130.5750 | 4 | 4 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 3,411.6667 | 3 | 3 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase | Mycobacterium tuberculosis H37Rv | IC50 | 2,500.0000 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | Ki | 363.0000 | 1 | 1 |
| Liver carboxylesterase B-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0450 | 1 | 1 |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | IC50 | 11.0400 | 5 | 5 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 5.2150 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 0.4620 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 2.5290 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.2260 | 2 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.4400 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | Ki | 2.1100 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 1.0597 | 2 | 2 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.0595 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0438 | 27 | 28 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 0.3900 | 4 | 4 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 5.0025 | 4 | 4 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.3763 | 20 | 20 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 0.0841 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.2178 | 37 | 42 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 0.3456 | 10 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | IC50 | 0.0055 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Gallus gallus (chicken) | Ki | 0.0019 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.3363 | 30 | 31 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.0204 | 72 | 85 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 | 14.3000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | IC50 | 0.0087 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Ki | 5.6576 | 17 | 20 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | Ki | 0.2406 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 3.1729 | 16 | 20 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | IC50 | 0.0041 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | IC50 | 0.3256 | 11 | 13 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.3319 | 30 | 31 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | Ki | 0.0024 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.0124 | 76 | 85 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | IC50 | 0.7150 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | IC50 | 5.0025 | 4 | 4 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | Ki | 0.3463 | 22 | 22 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | Ki | 0.0572 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 0.1748 | 54 | 63 |
| Nicotinamide N-methyltransferase | Homo sapiens (human) | IC50 | 3.6200 | 1 | 1 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0005 | 1 | 1 |
| Olfactory receptor 51E2 | Homo sapiens (human) | IC50 | 0.1600 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 4,117.5000 | 2 | 2 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 564.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 208.3367 | 9 | 10 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 337.1452 | 10 | 10 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 1,813.8445 | 37 | 40 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 62.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2,018.7250 | 5 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 907.5235 | 24 | 26 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 523.7468 | 22 | 22 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 52.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | IC50 | 1,500.0000 | 1 | 2 |
| Prostaglandin-H2 D-isomerase | Mus musculus (house mouse) | IC50 | 1,500.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Protoporphyrinogen oxidase | Zea mays | IC50 | 0.0032 | 1 | 1 |
| Retinoic acid receptor alpha | Homo sapiens (human) | IC50 | 0.0360 | 1 | 1 |
| Retinoic acid receptor alpha | Mus musculus (house mouse) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor alpha | Homo sapiens (human) | Ki | 0.0144 | 2 | 2 |
| Retinoic acid receptor beta | Homo sapiens (human) | IC50 | 0.0050 | 1 | 1 |
| Retinoic acid receptor beta | Mus musculus (house mouse) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor beta | Homo sapiens (human) | Ki | 0.0108 | 2 | 2 |
| Retinoic acid receptor gamma | Mus musculus (house mouse) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | IC50 | 0.0260 | 1 | 1 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Ki | 0.0112 | 2 | 2 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 0.0139 | 3 | 3 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-beta | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Retinoic acid receptor RXR-gamma | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 2 |
| Ribonucleoside-diphosphate reductase large subunit | Homo sapiens (human) | IC50 | 997.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 1.3750 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 10.0000 | 1 | 1 |
| Smoothened homolog | Homo sapiens (human) | IC50 | 0.0222 | 8 | 8 |
| Smoothened homolog | Mus musculus (house mouse) | IC50 | 0.0700 | 8 | 8 |
| Smoothened homolog | Homo sapiens (human) | Ki | 0.0142 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 18.5000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 72.8333 | 3 | 3 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 22.0000 | 2 | 2 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 18.5000 | 1 | 1 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | Ki | 24.0000 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 74.5000 | 2 | 2 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Soluble acetylcholine receptor | Aplysia californica (California sea hare) | Ki | 1.0466 | 3 | 3 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 64.3000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 50.5000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 75.3267 | 1 | 4 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 347.8351 | 1 | 4 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 428.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Sonic hedgehog protein | Homo sapiens (human) | IC50 | 0.8825 | 2 | 2 |
| Sonic hedgehog protein | Mus musculus (house mouse) | IC50 | 0.0077 | 3 | 3 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.4000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 1,750.0000 | 2 | 2 |
| Translocator protein | Rattus norvegicus (Norway rat) | Ki | 0.5063 | 2 | 4 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 5.5000 | 1 | 1 |
| Tyrosine-protein phosphatase 1 | Saccharomyces cerevisiae S288C | IC50 | 1.2000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | Ki | 1,600.0000 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 100.0000 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 100.0000 | 1 | 1 |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 2 |
| Vesicular glutamate transporter 3 | Rattus norvegicus (Norway rat) | Ki | 0.0400 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 125.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 73.4500 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 21.9000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 21.9000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 21.9000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | EC50 | 25.3333 | 3 | 3 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | EC50 | 29.0000 | 3 | 3 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | EC50 | 110.0000 | 2 | 2 |
| Acetylcholine receptor subunit epsilon | Homo sapiens (human) | EC50 | 65.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Kd | 0.2931 | 3 | 5 |
| Albumin | Homo sapiens (human) | Kd | 52.8000 | 5 | 5 |
| Albumin | Rattus norvegicus (Norway rat) | Kd | 105.6000 | 3 | 3 |
| calcineurin A1, putative | Candida dubliniensis CD36 | EC50 | 180.0000 | 1 | 1 |
| cell division cycle 42 (GTP binding protein, 25kDa), partial | Homo sapiens (human) | EC50 | 30.0000 | 2 | 2 |
| Cellular retinoic acid-binding protein 1 | Mus musculus (house mouse) | Kd | 0.2000 | 1 | 1 |
| Cellular retinoic acid-binding protein 2 | Mus musculus (house mouse) | Kd | 0.2000 | 1 | 1 |
| Chain A, Acetyl-CoA carboxylase 2 | Homo sapiens (human) | Kd | 0.0010 | 1 | 1 |
| Chain A, Phospholipase A2 isoform 3 | Naja sagittifera | Kd | 6.4000 | 1 | 1 |
| Chain A, Retinoic acid receptor beta | Homo sapiens (human) | Kd | 0.0020 | 1 | 1 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Kd | 54.0000 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Kd | 470.0000 | 1 | 1 |
| Glycoprotein IIb | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| GTP-binding protein (rab7) | Canis lupus familiaris (dog) | EC50 | 30.0000 | 1 | 1 |
| heat shock protein 90 | Candida albicans | EC50 | 120.0330 | 3 | 4 |
| Integrin beta | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | EC50 | 40.6667 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 21.3260 | 14 | 15 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 3.1424 | 20 | 24 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | EC50 | 10.7398 | 12 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 30.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | EC50 | 0.1270 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | EC50 | 55.2158 | 6 | 6 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | EC50 | 3,948.0836 | 10 | 11 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Kd | 0.0011 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | EC50 | 9.3127 | 23 | 27 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 10.7398 | 12 | 12 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | EC50 | 10.5635 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | EC50 | 13.6576 | 14 | 15 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | EC50 | 9.0000 | 1 | 1 |
| Rac1 protein | Homo sapiens (human) | EC50 | 30.0000 | 2 | 2 |
| ras protein, partial | Homo sapiens (human) | EC50 | 30.0000 | 2 | 2 |
| Ras-related protein Rab-2A | Canis lupus familiaris (dog) | EC50 | 30.0000 | 1 | 1 |
| Retinoic acid receptor alpha | Homo sapiens (human) | EC50 | 0.0398 | 5 | 5 |
| Retinoic acid receptor beta | Homo sapiens (human) | EC50 | 0.0035 | 4 | 4 |
| Retinoic acid receptor gamma | Homo sapiens (human) | EC50 | 0.0171 | 4 | 4 |
| Retinoic acid receptor gamma | Homo sapiens (human) | Kd | 0.0260 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | EC50 | 5.0000 | 2 | 2 |
| Retinoic acid receptor RXR-beta | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Retinoic acid receptor RXR-gamma | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | EC50 | 30.0000 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 30.0000 | 2 | 2 |
| Smoothened homolog | Homo sapiens (human) | EC50 | 0.0025 | 2 | 2 |
| Smoothened homolog | Mus musculus (house mouse) | EC50 | 0.0034 | 2 | 2 |
| Smoothened homolog | Homo sapiens (human) | Kd | 0.0975 | 1 | 1 |
| Stromelysin-1 | Homo sapiens (human) | Kd | 25,000.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 152,369.0000 | 2 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| Transporter | Rattus norvegicus (Norway rat) | EC50 | 51.0000 | 1 | 1 |