Gas Gangrene

A severe condition resulting from bacteria invading healthy muscle from adjacent traumatized muscle or soft tissue. The infection originates in a wound contaminated with bacteria of the genus CLOSTRIDIUM. C. perfringens accounts for the majority of cases (over eighty percent), while C. noyvi, C. septicum, and C. histolyticum cause most of the other cases.

Synonym
Gas Gangrene

Excerpt	Reference
"Clostridial gas gangrene is a well recognized complication of traumatic and surgical wounds, and is associated with an overall mortality rate of 25% (5, 22)."	( Gill, W; Howatson, A; Long, WB, 1976)
"Gas gangrene is caused by multiple species of Chlostridium, generally as a complication of traumatismus producing necrotic infections."	( Morcate, JJ; Saxena, AK; Schleef, J; Tsokas, J; Willital, GH, 1996)
"Nonclostridial gas gangrene is extremely rare but life-threatening."	( Itoman, M; Ohwada, T; Shindo, M; Soma, K; Takahira, N; Tanaka, K, 2002)
"Gas gangrene is a rare and rapidly progressive process with the propensity for devastating consequences."	( Bale, RS; Goyal, RW; Ng, AB, 2003)
"Gas gangrene is extremely rare in patients with ulcerative colitis or Crohn's disease and immunosuppression."	( Freitag, M; Jackisch, T; Ludwig, K, 2006)
"Gas gangrene is a potentially fatal disease that is primarily caused by the ubiquitous, anaerobic bacteria Clostridium perfringens and Clostridium septicum."	( Awad, MM; Chakravorty, A; Cheung, JK; Choo, JM; Hiscox, TJ; Lyras, D; Rood, JI, 2014)
"Traumatic gas gangrene is a fatal infection mainly caused by Clostridium perfringens."	( Hu, N; Huang, W; Jiang, DM; Liu, R; Shao, ZW; Wu, Q; Wu, XH; Xia, T; Yang, SH; Ye, ZW, 2015)

Excerpt	Reference
"Gas gangrene has been associated with severe trauma involving penetrating wounds, compound fractures, extensive soft-tissue injury, intramuscular injection of epinephrine, and interruption of arterial blood supply."	( Chin, RL; Garmel, G; Martinez, R, 1993)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	322 (75.94)	23.3326
1990's	44 (10.38)	12.5806
2000's	33 (7.78)	18.1394
2010's	23 (5.42)	28.8240
2020's	2 (0.47)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	4	0
ethanolamine	low	1	0
hydrogen carbonate	low	1	0
hydrogen	low	1	0
iodine	low	1	0
endolysin	low	1	0
methanol	low	1	0
4-aminobenzoic acid	low	1	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
phenytoin	low	1	0
antipyrine	low	1	0
aspirin	low	1	0
azathioprine	low	1	0
benzothiazide	low	2	0
caffeine	low	1	0
ciprofloxacin	low	1	0
deferoxamine	low	1	0
amphetamine	low	1	0
diazoxide	low	1	0
dibucaine	low	1	0
diclofenac	low	2	0
pentetic acid	low	2	0
ethacrynic acid	low	1	0
gentamicin	low	4	0
glafenine	low	1	0
hexetidine	low	1	0
lidocaine	low	1	0
mafenide	low	2	0
edaravone	low	1	0
mechlorethamine	low	1	0
mesalamine	low	1	0
metronidazole	low	20	0
nifedipine	low	1	0
pentobarbital	low	1	0
prochlorperazine	low	1	0
promazine	low	1	0
promethazine	low	1	0
secobarbital	low	1	0
sulfadiazine	low	1	0
sulfamerazine	low	1	0
sulfanilamide	low	4	0
sulfathiazole	low	1	0
sulfobromophthalein	low	1	0
suramin	low	1	0
thiotepa	low	1	0
triazolam	low	1	0
prednisolone	low	2	0
cephaloridine	low	5	0
thyroxine	low	1	0
prednisone	low	3	0
penicillin g	low	35	0
metaraminol	low	2	0
chloramphenicol	low	26	0
lysine	low	1	0
cyanides	low	1	0
sucrose	low	1	0
cephalothin	low	8	0
kanamycin a	low	3	0
phenylephrine	low	1	0
edetic acid	low	6	0
methicillin	low	1	0
cloxacillin	low	1	0
oxacillin	low	2	0
ampicillin	low	9	0
ethylene oxide	low	2	0
phencyclidine	low	1	0
cyclizine	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
quinoxalines	low	1	0
framycetin	low	3	0
ephedrine	low	1	0
emetine	low	1	0
erythromycin	low	4	0
levonorgestrel	low	1	0
vancomycin	low	2	0
paraquat	low	1	0
streptomycin	low	10	0
carbenicillin	low	1	0
trimethaphan	low	1	0
silver	low	1	0
barium sulfate	low	1	0
silver nitrate	low	1	0
calcium sulfate	low	3	0
ozone	low	1	0
trolamine salicylate	low	1	0
cephalexin	low	1	0
phenyl acetate	low	1	0
4-methoxyamphetamine	low	1	0
transferrin	low	2	0
amoxicillin	low	2	0
etoposide	low	1	0
amikacin	low	2	0
propiconazole	low	7	0
itraconazole	low	1	0
aluminum phosphate	low	1	0
glucose, (beta-d)-isomer	low	1	0
cephalosporin c	low	2	0
fluorodeoxyglucose f18	low	1	0
octadecyl palmitate	low	1	0
fibrinogen	low	1	0
acetylsalicylic acid lysinate	low	1	0
cobalt	low	2	0
imipenem, anhydrous	low	4	0
methotrexate	low	1	0
povidone-iodine	low	1	0
anatoxin a	low	3	0
glycogen	low	2	0
oxytocin	low	1	0
inositol 3-phosphate	low	1	0
strychnine	low	1	0
meropenem	low	2	0
cefoxitin	medium	4	1
clindamycin	low	18	0
fosfomycin	low	1	0
dactinomycin	low	1	0
potassium permanganate	low	1	0
buprenorphine	low	1	0
lincomycin	low	5	0
quinine	low	2	0
thymic factor, circulating	low	1	0
sphingosine	low	1	0
quercetin	low	1	0
bilirubin	low	2	0
amphotericin b	low	2	0
naloxone	medium	1	1
morphine	low	2	0
aluminum	low	1	0
naltrexone	low	1	0
sulfur	low	1	0
nitrofurantoin	low	2	0
amoxicillin-potassium clavulanate combination	low	2	0
acebutolol	low	1	0
pituitrin	low	1	0
rifamycins	low	1	0
acid phosphatase	low	2	0
ceruletide	medium	1	1
subtilin	low	1	0
beta-endorphin	medium	1	1
phosphatidylcholines	low	5	0
sodium hypochlorite	low	2	0
piperacillin, tazobactam drug combination	low	1	0
1-methoxyerythrabyssin ii	low	1	0
insulin, isophane	low	2	0
glycolipids	low	1	0
colistin	low	1	0
hydroxocobalamin	low	1	0
heme	low	1	0
leukotoxin	low	2	0
novobiocin	low	1	0
tetracycline	low	26	0
chlortetracycline	low	5	0
oxytetracycline, anhydrous	low	4	0
rolitetracycline	low	5	0
tigecycline	low	1	0
caseins	low	2	0
hyaluronoglucosaminidase	low	2	0
guanosine 5'-o-(3-thiotriphosphate)	low	1	0
rifampin	low	5	0
methylnitronitrosoguanidine	low	1	0
prodigiosin	low	1	0
guanosine 5'-o-(1-thiotriphosphate)	low	1	0
eye	low	3	0

Protein Targets (1,323)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	5	0	0	5
thioredoxin reductase	25	0	0	25
USP1 protein, partial	23	0	0	23
TDP1 protein	40	0	0	40
vitamin D3 receptor isoform VDRA	21	0	0	21
importin subunit beta-1 isoform 1	6	0	0	6
flap endonuclease 1	12	0	0	12
serine/threonine-protein kinase PLK1	8	0	0	8
snurportin-1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
DNA polymerase eta isoform 1	10	0	0	10
DNA polymerase iota isoform a (long)	23	0	0	23
urokinase-type plasminogen activator precursor	8	0	0	8
plasminogen precursor	8	0	0	8
urokinase plasminogen activator surface receptor precursor	8	0	0	8
geminin	32	0	0	32
DNA polymerase kappa isoform 1	16	0	0	16
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	1	2	6
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	2	2	4
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Sialidase	0	3	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	21	0	0	21
Genome polyprotein	0	0	1	1
AR protein	42	0	0	42
thyroid stimulating hormone receptor	19	0	0	19
glucocorticoid receptor [Homo sapiens]	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	34	0	0	34
estrogen nuclear receptor alpha	54	0	0	54
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
Histone H2A.x	20	0	0	20
chromobox protein homolog 1	25	0	0	25
transcriptional regulator ERG isoform 3	6	0	0	6
Polyphenol oxidase 2	0	4	0	6
Cellular tumor antigen p53	28	0	0	28
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	4	1	5
Dihydropteroate synthase	0	0	1	1
5-hydroxytryptamine receptor 2C	0	5	2	8
5-hydroxytryptamine receptor 2A	0	8	2	10
5-hydroxytryptamine receptor 1A	0	11	2	13
5-hydroxytryptamine receptor 1B	0	8	2	10
5-hydroxytryptamine receptor 1D	0	2	2	4
5-hydroxytryptamine receptor 1F	0	2	2	4
5-hydroxytryptamine receptor 2B	0	4	2	6
5-hydroxytryptamine receptor 6	0	0	2	2
Sodium-dependent serotonin transporter	0	6	1	7
Sodium-dependent serotonin transporter	0	5	0	5
5-hydroxytryptamine receptor 7	0	0	2	2
5-hydroxytryptamine receptor 5A	0	0	2	2
5-hydroxytryptamine receptor 5B	0	0	2	2
5-hydroxytryptamine receptor 3A	0	0	2	2
5-hydroxytryptamine receptor 4	0	0	2	2
5-hydroxytryptamine receptor 3B	0	0	2	2
peripheral myelin protein 22	17	0	0	17
histone acetyltransferase KAT2A isoform 1	10	0	0	10
lamin isoform A-delta10	31	0	0	31
ATP-binding cassette sub-family C member 3	0	35	0	35
Multidrug resistance-associated protein 4	0	35	0	36
Bile salt export pump	0	51	0	51
Canalicular multispecific organic anion transporter 1	0	35	0	36
Aminoglycoside 3'-phosphotransferase	0	0	0	2
ATP-dependent phosphofructokinase	13	0	0	13
Chain A, Beta-lactamase	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	19	0	0	19
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	6
Beta-lactamase	0	0	0	6
apical membrane antigen 1, AMA1	7	0	0	7
Beta-lactamase	0	0	0	3
Bile salt export pump	0	11	0	11
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase SHV-1	0	0	0	6
Cytochrome P450 2C9	0	13	0	14
Beta-lactamase	0	0	0	7
Kappa-type opioid receptor	0	8	1	14
Solute carrier family 15 member 1	0	11	0	11
Solute carrier family 15 member 1	0	3	0	3
Cytochrome P450 2J2	0	8	0	8
B2 metallo-beta-lactamase	0	0	0	8
Solute carrier family 15 member 2	0	8	0	8
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	8	0	9
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	5
Solute carrier family 22 member 3	0	1	0	1
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Beta-2 adrenergic receptor	0	3	0	4
Sigma non-opioid intracellular receptor 1	0	4	1	5
Chain A, HADH2 protein	13	0	0	13
Chain B, HADH2 protein	13	0	0	13
Chain A, Cruzipain	10	0	0	10
interleukin 8	9	0	0	9
phosphopantetheinyl transferase	19	0	0	19
GLS protein	20	0	0	20
farnesoid X nuclear receptor	19	0	0	19
peroxisome proliferator-activated receptor delta	24	0	0	24
vitamin D (1,25- dihydroxyvitamin D3) receptor	21	0	0	21
tumor necrosis factor	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	43	0	0	43
Cytochrome P450 1A2	0	5	0	5
Cytochrome P450 3A4	0	12	1	13
Cytochrome P450 2D6	0	10	0	11
Cytochrome P450 2C19	0	2	0	2
Nuclear receptor ROR-gamma	10	0	0	10
Potassium voltage-gated channel subfamily H member 2	0	14	0	15
Aurora kinase B	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	1	8
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
Beta-lactamase	0	2	0	5
GLI family zinc finger 3	34	0	0	34
Beta-lactamase	0	1	0	6
Beta-lactamase	0	0	0	5
Metallo-beta-lactamase type 2	0	0	1	7
Metallo-beta-lactamase VIM-11	0	0	0	6
euchromatic histone-lysine N-methyltransferase 2	35	0	0	35
Metallo-beta-lactamase VIM-2	0	0	0	6
Beta-lactamase	0	0	0	5
Metallo-beta-lactamase	0	0	0	6
Beta-lactamase	0	1	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	14	0	0	14
thyroid hormone receptor beta isoform 2	29	0	0	29
DNA polymerase beta	7	0	0	7
Carbonic anhydrase 1	0	14	0	16
Carbonic anhydrase 2	0	16	3	21
60 kDa heat shock protein, mitochondrial	0	6	0	6
Beta-lactamase OXA-7	0	0	0	3
Spike glycoprotein	15	2	4	21
10 kDa heat shock protein, mitochondrial	0	6	0	6
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Thiosulfate sulfurtransferase	0	6	0	6
Metallo-beta-lactamase VIM-13	0	1	0	6
Efflux transporter	0	1	0	5
Beta-lactamase	0	0	0	5
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	1	0	5
Class D beta-lactamase	0	0	0	4
60 kDa chaperonin	0	7	0	7
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	0	0	5
Beta-lactamase	0	0	1	5
10 kDa chaperonin	0	7	0	7
Metallo-b-lactamase	0	0	0	9
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	7
Histamine H3 receptor	0	0	0	5
Beta-lactamase class B VIM-2	0	0	1	10
Beta-lactamase VIM-1	0	1	0	6
aldehyde dehydrogenase 1 family, member A1	32	0	0	32
regulator of G-protein signaling 4	14	0	0	14
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	2	2	1	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	2	2	1	5
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-9	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	1	2
ATAD5 protein, partial	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	28	0	0	28
retinoid X nuclear receptor alpha	28	0	0	28
67.9K protein	13	0	0	13
thyroid hormone receptor beta isoform a	14	0	0	14
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
Nicotinate phosphoribosyltransferase	0	3	0	3
Microtubule-associated protein tau	23	0	0	23
estrogen-related nuclear receptor alpha	40	0	0	40
arylsulfatase A	8	0	0	8
Bloom syndrome protein isoform 1	11	0	0	11
D(1A) dopamine receptor	9	0	0	9
neuropeptide S receptor isoform A	4	0	0	4
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	7	0	0	7
RAR-related orphan receptor gamma	32	0	0	32
thioredoxin glutathione reductase	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	22	0	0	22
IDH1	16	0	0	16
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
lethal factor (plasmid)	11	0	0	11
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	8	1	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	2	0	0	2
EWS/FLI fusion protein	15	0	0	15
cytochrome P450 2D6	15	0	0	15
glucocerebrosidase	8	0	0	8
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	9	0	0	9
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	8	0	8
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	4	0	5
Adenosine receptor A2a	0	5	0	7
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	7	0	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	15	4	0	20
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Chain A, Ferritin light chain	6	0	0	6
SMAD family member 2	10	0	0	10
Fumarate hydratase	5	0	0	5
SMAD family member 3	10	0	0	10
pregnane X nuclear receptor	37	0	0	37
G	13	0	0	13
polyprotein	5	0	0	5
P53	1	0	0	1
peroxisome proliferator activated receptor gamma	22	0	0	22
aryl hydrocarbon receptor	20	0	0	20
thyroid stimulating hormone receptor	15	0	0	15
activating transcription factor 6	14	0	0	14
v-jun sarcoma virus 17 oncogene homolog (avian)	22	0	0	22
peripheral myelin protein 22 isoform 1	6	0	0	6
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	8	0	0	8
heat shock protein beta-1	14	0	0	14
survival motor neuron protein isoform d	13	0	0	13
cytochrome P450 3A4 isoform 1	15	0	0	15
M-phase phosphoprotein 8	7	0	0	7
muscleblind-like protein 1 isoform 1	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	15	3	0	19
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Interferon beta	20	0	0	20
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Gamma-aminobutyric acid receptor subunit beta-1	15	3	0	19
Gamma-aminobutyric acid receptor subunit delta	15	3	0	19
Gamma-aminobutyric acid receptor subunit gamma-2	15	3	0	19
Glutamate receptor 2	19	0	0	21
Gamma-aminobutyric acid receptor subunit alpha-5	15	3	0	19
Gamma-aminobutyric acid receptor subunit alpha-3	15	3	0	19
Gamma-aminobutyric acid receptor subunit gamma-1	15	3	0	19
Gamma-aminobutyric acid receptor subunit alpha-2	15	3	0	19
Gamma-aminobutyric acid receptor subunit alpha-4	15	3	0	19
Gamma-aminobutyric acid receptor subunit gamma-3	15	3	0	19
Gamma-aminobutyric acid receptor subunit alpha-6	15	3	0	19
Gamma-aminobutyric acid receptor subunit beta-3	15	3	0	19
Gamma-aminobutyric acid receptor subunit beta-2	15	3	0	19
GABA theta subunit	15	3	0	19
Inositol hexakisphosphate kinase 1	13	0	0	13
ATPase family AAA domain-containing protein 5	15	0	0	15
Ataxin-2	19	0	0	19
Gamma-aminobutyric acid receptor subunit epsilon	15	3	0	19
Protein-arginine deiminase type-4	0	9	0	9
cytochrome P450 2C9, partial	13	0	0	13
Chain A, Putative fructose-1,6-bisphosphate aldolase	15	0	0	15
Luciferase	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
cytochrome P450 2D6 isoform 1	8	0	0	8
cytochrome P450 2C9 precursor	9	0	0	9
pyruvate kinase PKM isoform a	1	0	0	1
Histamine H2 receptor	16	0	0	16
caspase-1 isoform alpha precursor	4	0	0	4
Caspase-7	5	0	0	5
Inositol monophosphatase 1	7	0	0	7
Solute carrier organic anion transporter family member 1B3	0	6	0	10
Solute carrier organic anion transporter family member 1B1	0	4	0	8
Kappa-type opioid receptor	0	7	5	17
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	14	0	0	14
Potassium channel subfamily K member 2	0	2	2	4
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	1	0	1
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	6	4	10
Adenosine receptor A3	0	4	0	4
Replicase polyprotein 1ab	0	5	4	9
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	4	0	4
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	3	1	5
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	4	1	7
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	2	0	2
Guanine deaminase	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	3
Metallo-beta-lactamase VIM-19	0	0	0	4
Solute carrier family 22 member 8	0	6	0	7
Metallo-beta-lactamase VIM-2	0	0	0	5
BlaVIM-1	0	0	0	4
mitogen-activated protein kinase 1	9	0	0	9
Solute carrier family 22 member 8	0	4	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
Beta-lactamase	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	6
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	2	0	7
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 6	0	5	0	6
Beta-lactamase	0	0	0	4
Solute carrier family 22 member 7	0	2	0	3
Beta-lactamase	0	0	0	4
Beta-lactamase IMP-1	0	0	0	4
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	4	0	6
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	4
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 7	0	2	0	3
Beta-lactamase	0	1	0	3
endonuclease IV	4	0	0	4
WRN	3	0	0	3
Beta-lactamase	0	1	0	3
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase	0	0	0	2
phosphoglycerate kinase	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	12	0	0	12
streptokinase A precursor	0	0	6	6
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
50S ribosomal protein L36 2	0	4	1	5
Methionine--tRNA ligase, mitochondrial	0	0	1	1
PPM1D protein	3	0	0	3
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	2	4	6
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	3	3
Amyloid-beta precursor protein	0	4	0	4
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	4	6
Muscarinic acetylcholine receptor M2	0	11	0	12
Muscarinic acetylcholine receptor M4	0	11	0	12
Muscarinic acetylcholine receptor M5	0	10	0	11
Alpha-2A adrenergic receptor	0	13	2	15
Replicase polyprotein 1a	0	3	4	7
Replicase polyprotein 1ab	0	3	4	7
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	11	0	12
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	10	1	11
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	10	0	11
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	3	0	3
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	2	4	6
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	3	0	5
DNA gyrase subunit A	0	3	0	6
DNA gyrase subunit B	0	3	1	6
DNA topoisomerase 4 subunit A	0	2	0	2
DNA topoisomerase 4 subunit B	0	2	0	3
DNA topoisomerase 4 subunit A	0	2	0	3
DNA topoisomerase 2-alpha	0	3	1	12
DNA gyrase subunit A	0	3	0	5
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	5	0	5
Carbonic anhydrase 4	0	6	0	6
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase 15	0	5	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	1	0	10
5-hydroxytryptamine receptor 4	0	10	0	10
Alpha-1D adrenergic receptor	0	8	0	8
5-hydroxytryptamine receptor 2A	0	8	0	8
5-hydroxytryptamine receptor 2C	0	10	0	10
Histamine H1 receptor	0	8	0	8
D(3) dopamine receptor	0	8	0	8
5-hydroxytryptamine receptor 2B	0	8	0	8
Sodium-dependent dopamine transporter	0	4	0	4
Rap guanine nucleotide exchange factor 3	5	0	0	5
Glutathione S-transferase P	0	2	0	2
Alpha-tocopherol transfer protein	0	0	1	1
15-lipoxygenase, partial	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	14	0	0	14
caspase 7, apoptosis-related cysteine protease	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
estrogen receptor 2 (ER beta)	14	0	0	14
progesterone receptor	20	0	0	20
caspase-3	5	0	0	5
RAD51	0	1	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
huntingtin isoform 2	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
ATP-dependent translocase ABCB1	0	10	1	15
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	2	0	2
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Lysine-specific demethylase 4A	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	1	3
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Glutamate receptor 1	0	0	0	2
Glutamate receptor 3	0	0	0	2
Glutamate receptor 4	0	0	0	2
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	1	2
ATP-sensitive inward rectifier potassium channel 11	0	1	1	2
glp-1 receptor, partial	7	0	0	7
Smad3	7	0	0	7
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	4
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	3	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Albumin	0	3	7	10
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	1	0	3
UDP-glucuronosyltransferase 1-6	0	2	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	6
UDP-glucuronosyltransferase 1A4	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	7	1	8
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 4	0	3	0	3
Multidrug and toxin extrusion protein 1	0	4	0	4
P2Y purinoceptor 12	0	1	1	2
UDP-glucuronosyltransferase 1A7	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	1	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 2B17	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
NS5	0	0	1	1
Parkin	3	0	0	3
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
ATP-dependent translocase ABCB1	0	4	0	4
60 kDa chaperonin	0	3	0	3
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Chain A, GLUTATHIONE TRANSFERASE A1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain B, Glutathione S-transferase P1-1	0	1	0	1
Nrf2	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
nonstructural protein 1	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
serine-protein kinase ATM isoform a	1	0	0	1
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
histone deacetylase 9 isoform 3	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Hematopoietic prostaglandin D synthase	0	2	0	2
Glutathione S-transferase A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 6	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
UDP-glucose 4-epimerase	0	1	0	1
14 kDa phosphohistidine phosphatase	0	2	0	2
large T antigen	0	2	0	2
Glutaminyl-peptide cyclotransferase	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Prothrombin	0	1	1	3
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
DNA topoisomerase 2	0	0	0	1
Serum paraoxonase/arylesterase 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	2	0	3
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	3
Glutamate receptor ionotropic, NMDA 2B	0	2	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	4
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Glutamate receptor ionotropic, NMDA 2D	0	2	0	3
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Chain B, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	7
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
GALC protein	3	0	0	3
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Progesterone receptor	0	2	1	4
Potassium channel subfamily K member 3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	4
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	5
Cationic amino acid transporter 3	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 12	0	4	0	4
Carbonic anhydrase 3	0	4	0	4
Carbonic anhydrase 6	0	6	0	6
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Delta-type opioid receptor	0	7	2	13
Delta-type opioid receptor	0	9	4	14
Mu-type opioid receptor	0	9	4	16
Carbonic anhydrase 5A, mitochondrial	0	6	0	7
Carbonic anhydrase 7	0	4	0	4
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	8	2	11
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 13	0	4	0	4
Carbonic anhydrase 14	0	4	0	4
Carbonic anhydrase 5B, mitochondrial	0	4	0	5
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
cytochrome P450 2C19 precursor	6	0	0	6
microphthalmia-associated transcription factor isoform 9	0	3	0	3
Solute carrier organic anion transporter family member 2B1	0	2	0	3
Tumor necrosis factor	0	1	0	1
Neuraminidase	0	1	0	1
Platelet-activating factor receptor	1	0	0	2
Cystathionine gamma-lyase	0	2	0	2
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
Macrophage migration inhibitory factor	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
dopamine D1 receptor	3	0	0	3
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	2	0	0	2
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	3	4
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Kappa-type opioid receptor	0	6	4	11
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
TAR DNA-binding protein 43	4	0	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Opioid receptor, delta 1b	0	1	0	1
Solute carrier family 22 member 1	0	7	0	7
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	1	5
Muscarinic acetylcholine receptor M3	0	3	1	4
Muscarinic acetylcholine receptor M4	0	3	1	4
Muscarinic acetylcholine receptor M5	0	3	1	4
Muscarinic acetylcholine receptor M2	0	4	2	6
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	5	2	10
Mu-type opioid receptor	0	6	5	15
Delta-type opioid receptor	0	6	5	15
Mu-type opioid receptor	0	5	2	12
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
D(3) dopamine receptor	0	3	0	3
UDP-glucuronosyltransferase 1A8	0	0	0	2
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
pregnane X receptor	3	0	0	3
NFKB1 protein, partial	5	0	0	5
Thrombopoietin	3	0	0	3
beta-2 adrenergic receptor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
eyes absent homolog 2 isoform a	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Phospholipase A2, membrane associated	0	0	0	1
Alpha-1B adrenergic receptor	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Alpha-1A adrenergic receptor	0	5	0	5
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Potassium channel subfamily K member 2	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Estrogen receptor	0	0	2	2
Estrogen receptor beta	0	0	2	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Chain A, Gyrase	0	0	1	1
Genome polyprotein	0	1	1	2
DNA gyrase subunit B	0	1	0	1
interferon gamma precursor	0	0	0	2
Heat shock protein HSP 90-alpha	0	0	2	2
Heat shock protein HSP 90-beta	0	1	2	4
DNA gyrase subunit B	0	1	0	1
Cell division inhibitor SulA	0	0	0	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA topoisomerase	0	1	0	1
Microtubule-associated proteins 1A/1B light chain 3B	0	2	1	3
Microtubule-associated proteins 1A/1B light chain 3A	0	2	1	3
MecA	0	1	0	1
Valosin-containing protein	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Photosystem I iron-sulfur center	0	0	0	1
Beta-lactamase 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	2	1	3
Muscarinic acetylcholine receptor M4	0	0	1	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	8	2	15
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	9	0	9
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Mcl-1	0	1	0	1
Snq2p	0	0	0	3
neutrophil cytosol factor 1	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Aldo-keto reductase family 1 member B1	0	7	0	7
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	6	0	6
D(1A) dopamine receptor	0	6	0	6
D(4) dopamine receptor	0	3	0	3
Sodium-dependent noradrenaline transporter	0	6	0	6
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
D(1A) dopamine receptor	3	0	0	3
5-hydroxytryptamine receptor 6	0	6	0	6
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Low molecular weight protein-tyrosine phosphatase A	0	1	0	1
D	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Histamine H2 receptor	0	4	0	4
D(1B) dopamine receptor	0	1	0	1
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	1	0	1
Alpha-synuclein	1	3	0	4
D(2) dopamine receptor	0	1	0	1
D	0	1	0	1
Calmodulin-1	0	2	0	2
Calmodulin	0	0	1	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
galactokinase	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Cytochrome P450 1A1	0	2	1	3
Tyrosine-protein kinase Lck	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	2	1	3
Hepatocyte growth factor receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Aromatase	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	3	0	3
Serine/threonine-protein kinase B-raf	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Trypsin-3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Substance-K receptor	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier family 22 member 1	0	2	0	3
Cytochrome P450 2D4	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	0	1
Glycine receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	0	1
Glycine receptor subunit beta	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 10	0	0	1	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Aurora kinase A	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 13	0	1	0	1
Protein argonaute-2	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 2	0	1	0	1
Serine/threonine-protein kinase D3	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Cathepsin B	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C eta type	0	1	0	1
P2Y purinoceptor 2	0	1	1	2
Protein kinase C iota type	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 2	0	1	1	2
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
NAD-dependent protein deacetylase HST2	0	1	0	1
P2X purinoceptor 3	0	0	1	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
DNA primase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
P2Y purinoceptor 6	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Dual specificity protein phosphatase 5	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 8	0	1	0	1
RmtA	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
P2Y purinoceptor 11	0	1	1	2
P2X purinoceptor 7	0	0	1	1
Protein arginine N-methyltransferase 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (424)

Protein Targets (1,323)

Gas Gangrene

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (424)

Drugs Studied (191)

Protein Targets (1,323)