An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146).
ChEBI ID: 137626
| Member | Definition | Class |
|---|---|---|
| adrenosterone | A 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17. | adrenosterone |
| diethylstilbestrol | An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. | diethylstilbestrol |
| glycyrrhetyl 3-monoglucuronide | A triterpenoid saponin that is the 3-O-beta-glucuronide of glycyrrhetic acid. It is a metabolite of glycyrrhizin contained in licorice and potentially a causative agent in the pathogenesis of pseudoaldosteronism. | glycyrrhetic acid 3-O-glucuronide |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 5,564 (68.46) | 18.7374 |
| 1990's | 1,101 (13.55) | 18.2507 |
| 2000's | 891 (10.96) | 29.6817 |
| 2010's | 485 (5.97) | 24.3611 |
| 2020's | 86 (1.06) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 322 (3.72%) | 5.53% |
| Reviews | 506 (5.84%) | 6.00% |
| Case Studies | 325 (3.75%) | 4.05% |
| Observational | 1 (0.01%) | 0.25% |
| Other | 7,508 (86.68%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 5.0119 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 0.7762 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 54.5111 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 20.5523 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 27.7715 | 7 | 17 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 23.0999 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 20.9924 | 3 | 7 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 23.7358 | 2 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 22.3872 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 22.3872 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 43.6486 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 30.9008 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 4.8975 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 64.6116 | 1 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.0911 | 11 | 29 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 23.3237 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 45.8749 | 6 | 15 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 45.4422 | 3 | 6 |
| G | Vesicular stomatitis virus | Potency | 43.6486 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 18.1773 | 2 | 4 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 22.9658 | 2 | 6 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 22.1060 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 28.6493 | 4 | 9 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 54.2612 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 36.1214 | 2 | 4 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 15.8489 | 1 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 125.7890 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 43.6486 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 47.2868 | 2 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 43.6486 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 43.6486 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.8489 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 26.7640 | 2 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 28.7968 | 1 | 2 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.4478 | 3 | 8 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 27.5004 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 22.3872 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 8.2188 | 3 | 7 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 32.1968 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 34.6238 | 3 | 6 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 46.7037 | 3 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 40.4288 | 3 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 23.8620 | 1 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 35.7188 | 2 | 6 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 37.6919 | 3 | 4 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 36.1095 | 4 | 6 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 31.6228 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 7.6922 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 24.8445 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 20.3453 | 3 | 8 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 44.9647 | 1 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 47.9729 | 3 | 5 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 65.6297 | 2 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 61.1624 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.9009 | 2 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 54.2612 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 4.7900 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 1.3690 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 3.1400 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 1.9980 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 50.8190 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 26.6190 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 50.8190 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 26.6190 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 12.8920 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 5.9860 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 25.5500 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 2.8560 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 1.6660 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 9.0130 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 5.0600 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 2.2080 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.2480 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.4600 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 3.6700 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 3.6400 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2080 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.2480 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2080 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.2480 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 10.8260 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 5.3210 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 14.1270 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 5.2970 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 11.6980 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 5.3400 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 15.1510 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 2.2010 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 14.1254 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 22.0880 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 12.7550 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 0.5000 | 2 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 91.5000 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 91.5000 | 1 | 2 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 17.7450 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | Ki | 8.8720 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 7.7630 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 3.8820 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 13.3210 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 4.4400 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 8.7960 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 2.9870 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 2.7180 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 0.9580 | 1 | 1 |
| Estrogen receptor | Homo sapiens (human) | IC50 | 0.1312 | 6 | 6 |
| Estrogen receptor | Homo sapiens (human) | Ki | 0.0002 | 5 | 5 |
| Estrogen receptor beta | Homo sapiens (human) | IC50 | 0.1588 | 4 | 4 |
| Estrogen receptor beta | Homo sapiens (human) | Ki | 0.0003 | 3 | 3 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 10.6000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 10.6000 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 4.8180 | 1 | 1 |
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | IC50 | 12.5893 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 4.5630 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 1.8250 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 32.9030 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 5.7780 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 2.3450 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 15.1710 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 3.6540 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 18.4320 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 3.9070 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | IC50 | 14.6000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 2.9630 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 5.6000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 14.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 1.0710 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.8510 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 3.6700 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 3.6400 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 12.4920 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 6.6370 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 9.5530 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | Ki | 3.1840 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 4.3590 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 14.2330 | 1 | 1 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 25.9250 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | Ki | 10.4010 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | EC50 | 0.0025 | 5 | 5 |
| Estrogen receptor beta | Homo sapiens (human) | EC50 | 0.0045 | 2 | 2 |
| Estrogen-related receptor gamma | Homo sapiens (human) | EC50 | 0.6300 | 2 | 2 |