Osteoporotic Fractures

Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.

Synonym
Osteoporotic Fractures

Excerpt	Reference
"Osteoporotic fractures are associated with significant morbidity and mortality with an enormous impact on society and the lives of affected individuals."	( Boonen, S, 2010)
"Osteoporotic fractures are associated with premature mortality."	( Bliuc, D; Center, JR; Eisman, JA; Nguyen, ND; Nguyen, TV, 2011)
"Osteoporotic fractures are a frequent cause of functional disabilities and loss of quality of life."	( Lange, U; Müller-Ladner, U; Pfeilschifter, J, 2011)
"Osteoporotic fractures are common during osteoporotic states."	( Alhabshi, SM; Das, S; Estai, MA; Fadzilah, FM; Shuid, AN; Soelaiman, IN; Suhaimi, FH, 2011)
"The Study of Osteoporotic Fractures is a prospective cohort of 9,704 postmenopausal women recruited from population based listings in 1986 and followed for more than 20 years."	( Eisner, BH; Kahn, AJ; Lui, LY; Sadetsky, N; Sorensen, MD; Stoller, ML; Stone, KL, 2012)
"Osteoporotic fractures are a crucial cause of morbidity and mortality in patients with fragility fractures and impose huge economic burden on health care services."	( Aghamirsalim, M; Sorbi, R, 2012)
"Major osteoporotic fractures are associated with decreased quality of life and high costs."	( D'Amelio, P; Isaia, GC, 2013)
"Osteoporotic fractures are associated with excess morbidity and mortality."	( Abrahamsen, B; Brixen, K; Frost, M; Poulsen, MH; Walter, S, 2014)
"Osteoporotic fractures are a major cause of morbidity in the population."	( Beaudart, Ch; Bruyere, O; Buckinx, F; Disteche, S; Neuprez, A; Reginster, JY; Slomian, J, 2014)
"Osteoporotic fractures are a public health problem and their incidence and subsequent economic and social costs are expected to rise in the next future."	( Carda, S; Cisari, C; Invernizzi, M, 2015)
"Osteoporotic fractures are associated with mortality in postmenopausal woman."	( Chen, YC; Cheng, TT; Lin, WC; Lui, CC; Su, FM, 2015)
"Osteoporotic fractures are associated with high morbidity, mortality, and cost."	( Beyth, RJ; Cauley, JA; Garvan, C; Johnson, KC; LaMonte, MJ; Li, W; Limacher, M; Manini, T; Sarto, GE; Sattari, M; Sullivan, SD; Wactawski-Wende, J, 2017)
"Osteoporotic fractures are common in patients with chronic kidney disease (CKD)."	( de Jongh, R; Goldsmith, D; Lips, P, 2017)
"Resultant osteoporotic fractures are a significant contributor of economic and social burden among elderly osteoporosis patients."	( Baidya, S; Barron, R; Fujiwara, S; Hamaya, E; Miyauchi, A; Nicholls, RJ; Pinto, L; Takada, J; Weston, A, 2018)
"BACKGROUND Osteoporotic fractures are common in postmenopausal women and associated with complications."	( Han, B; Jing, J; Li, J; Wei, Y; Zhang, Y, 2020)
"Anemia and osteoporotic fractures are conditions that are associated with increased morbidity and mortality."	( Herlitz, H; Johansson, P; Karlsson, M; Kristjansdottir, HL; Lerner, UH; Lewerin, C; Lorentzon, M; Mellström, D; Ohlsson, C; Vandenput, L, 2022)
"The treatment of osteoporotic fractures is difficult, and to minimize the negative result or poor functional rehabilitation, this study focuses on hydrogen water (HRW) to test its effect on the process of menopausal osteoporotic fracture healing and its relationship with autophagy and to try to reveal the potential mechanism of action of HRW on osteoporotic fractures."	( Dong, W; Guo, J; Hou, Z; Tian, S; Wang, Y; Wang, Z; Zhang, X; Zhang, Y, 2022)

Excerpt	Reference
"Osteoporotic fractures have a tremendous impact on quality of life and may contribute to fatality, but half of patients may discontinue their anti-osteoporosis medication."	( Chen, CH; Chen, YM; Deng, YL; Hsu, CS; Hsu, CY; Lee, HT; Liu, CF; Ou, SF; Shih, CH; Yang, SH, 2022)

Excerpt	Reference
"Products have been used for the treatment of osteoporotic fractures of the proximal humerus, distal radius, vertebra, hip, and tibia plateau."	( Alt, V; Van Lieshout, EM, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	12 (1.17)	18.1394
2010's	768 (74.71)	28.8240
2020's	248 (24.12)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	4	0
beta-alanine	low	2	0
methane	low	2	0
citric acid, anhydrous	low	1	0
creatine	low	1	0
dimethylglycine	low	1	0
glycine	low	1	0
dalteparin	medium	4	1
histamine	low	2	0
hydrogen	low	1	0
dihydroxyphenylalanine	low	1	0
phytic acid	medium	2	1
phthalic acid	low	1	0
diphosphoric acid	low	1	0
pyridoxine	low	1	0
sarcosine	low	1	0
spermidine	low	1	0
sulfur dioxide	low	2	0
taurine	low	1	0
trimethyloxamine	low	1	0
uric acid	low	17	0
acetaminophen	low	2	0
alendronate	medium	128	17
anastrozole	medium	2	1
aspirin	medium	2	1
azathioprine	low	1	0
bupivacaine	low	1	0
valproic acid	low	1	0
etidronate	medium	34	6
hydroxychloroquine	low	2	0
lidocaine	medium	2	2
lansoprazole	low	1	0
letrozole	low	1	0
metformin	medium	9	2
nitrendipine	low	1	0
omeprazole	low	2	0
oxybutynin	low	1	0
pamidronate	medium	7	1
pantoprazole	low	1	0
propiomazine	low	1	0
protoporphyrin ix	low	1	0
rabeprazole	low	1	0
risperidone	low	1	0
semustine	low	1	0
risedronic acid	medium	60	13
2,4-thiazolidinedione	low	1	0
ticlopidine	low	1	0
trazodone	low	1	0
urethane	medium	1	1
zaleplon	low	1	0
zolpidem	low	1	0
zopiclone	low	1	0
prednisolone	medium	9	1
thyroxine	low	8	0
aldosterone	low	1	0
prednisone	medium	7	1
triiodothyronine	low	1	0
alanine	low	1	0
lysine	low	10	0
levodopa	low	1	0
lactose	low	1	0
medroxyprogesterone acetate	low	1	0
valine	low	1	0
arginine	low	9	0
acrylamide	low	1	0
methylmethacrylate	low	1	0
thiophenes	medium	49	5
catechin	low	1	0
quinazolines	low	1	0
adamantane	medium	1	1
isoxazoles	medium	1	1
azacitidine	low	1	0
betamethasone	medium	1	1
limestone	medium	7	2
malondialdehyde	medium	1	1
3-hydroxyflavone	low	1	0
dehydroepiandrosterone sulfate	low	1	0
durapatite	medium	13	1
vancomycin	low	1	0
d-alpha tocopherol	low	1	0
bisphenol a-glycidyl methacrylate	medium	1	1
titanium	medium	7	1
cadmium	low	2	0
tricalcium phosphate	medium	15	1
calcium sulfate	medium	4	1
ozone	low	1	0
trolamine salicylate	low	5	0
clodronic acid	medium	2	2
fluorides	low	3	0
cetylpyridinium chloride anhydrous	low	1	0
fenoxycarb	low	1	0
simvastatin	low	1	0
cabergoline	low	1	0
raloxifene hydrochloride	medium	40	5
finasteride	low	1	0
aromasil	medium	1	1
clopidogrel	low	1	0
lamivudine	low	1	0
ibandronic acid	medium	21	2
emtricitabine	low	1	0
fluorophosphate	low	1	0
triazoles	medium	2	1
fluorodeoxyglucose f18	low	2	0
zoledronic acid	medium	92	21
morpholinopropane sulfonic acid	medium	1	1
6-amino-1-hydroxyhexane-1,1-diphosphonate	low	1	0
sesamin	low	1	0
nicotine	low	1	0
equol	low	1	0
homocysteine	medium	8	4
lopinavir	low	1	0
calcium phosphate, dibasic, dihydrate	low	1	0
vitamin b 6	low	2	0
pyridinoline	low	1	0
deoxypyridinoline	low	3	0
tadalafil	low	1	0
pentosidine	low	9	0
parecoxib	medium	1	1
n(6)-carboxymethyllysine	low	2	0
methotrexate	low	2	0
ym 529	medium	8	6
ezetimibe	low	1	0
bazedoxifene	medium	14	4
biotin	low	1	0
ropivacaine	medium	1	1
organophosphonates	low	3	0
ly 353381	low	1	0
deflazacort	low	2	0
dabigatran	low	5	0
lasofoxifene	low	1	0
cortisone	low	1	0
ritonavir	low	1	0
s-adenosylhomocysteine	low	1	0
fibrin	low	1	0
oxytocin	low	1	0
abacavir	low	1	0
mometasone furoate	low	1	0
lignans	low	1	0
tibolone	low	4	0
arachidonic acid	low	1	0
retinol	medium	5	1
tacrolimus	low	1	0
eicosapentaenoic acid	low	1	0
mycophenolic acid	low	1	0
decitabine	low	1	0
tenofovir	low	8	0
bromochloroacetic acid	low	1	0
isomethyleugenol	low	1	0
pyrophosphate	medium	2	1
nsc 4347	low	1	0
capsaicin	low	1	0
tamoxifen	low	6	0
toremifene	low	2	0
lithium	low	1	0
nitrogen dioxide	low	4	0
freedom	medium	2	1
nitinol	low	1	0
osteoprotegerin	medium	19	2
abacavir, lamivudine drug combination	low	1	0
sphingosine	low	3	0
dinoprostone	low	1	0
calcitriol	medium	11	1
vitamin k semiquinone radical	low	9	0
beta carotene	medium	1	1
retinol palmitate	medium	1	1
vitamin d 2	medium	4	1
cholecalciferol	medium	31	8
pulmicort	low	2	0
menaquinone 6	medium	5	2
sphingosine 1-phosphate	low	3	0
vitamin k 1	low	1	0
menaquinone 7	medium	1	1
morphine	medium	1	1
icariin	low	1	0
strontium	low	8	0
gallium	low	1	0
phosphorus	low	10	0
strontium radioisotopes	low	1	0
25-hydroxyvitamin d 2	low	7	0
selenium	low	1	0
oxalates	low	1	0
gadolinium dtpa	low	2	0
ergoline	low	1	0
dutasteride	low	1	0
s 1743	low	1	0
dexlansoprazole	low	1	0
andarine	low	1	0
rivaroxaban	low	2	0
sr 59230a	low	1	0
tocotrienols	low	1	0
odanacatib	medium	12	3
apixaban	low	1	0
saracatinib	low	1	0
alpha-synuclein	low	1	0
ronacaleret	low	1	0
acebutolol	medium	1	1
mk 2866	low	1	0
sitagliptin phosphate	medium	2	1
losartan potassium	medium	2	1
pituitrin	low	1	0
acid phosphatase	medium	7	3
jaw	low	1	0
calcitonin	medium	5	4
glucagon-like peptide 1	low	1	0
incretins	low	1	0
c-peptide	low	2	0
vendex	medium	12	1
tyrosyl-glutamyl-tyrosyl-glutamic acid	low	1	0
s-adenosylmethionine	low	1	0
cardiovascular agents	low	1	0
piperidines	low	1	0
interleukin-8	low	1	0
exenatide	low	1	0
natriuretic peptide, brain	low	2	0
ascorbic acid	low	3	0
tetracycline	low	1	0
warfarin	low	10	0
whitlockite	low	1	0
transforming growth factor beta	low	5	0
phytoestrogens	low	3	0
rome	low	4	0
vitamin b 12	medium	8	4
technetium tc 99m medronate	low	1	0
exudates	medium	7	1
entecavir	low	1	0
guanine	low	1	0
folic acid	medium	8	4
allopurinol	low	3	0
vardenafil dihydrochloride	low	1	0
ferric carboxymaltose	medium	1	1
abaloparatide	medium	38	14
leptin	low	6	0

Protein Targets (1,690)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Maltase-glucoamylase, intestinal	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	1	2
Glycogen synthase kinase-3 beta	0	2	1	3
Probable maltase-glucoamylase 2	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
glp-1 receptor, partial	12	0	0	12
USP1 protein, partial	29	0	0	29
TDP1 protein	58	0	0	58
Smad3	11	0	0	11
apical membrane antigen 1, AMA1	12	0	0	12
cellular tumor antigen p53 isoform a	7	0	0	7
importin subunit beta-1 isoform 1	8	0	0	8
mitogen-activated protein kinase 1	17	0	0	17
snurportin-1	8	0	0	8
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	10	0	0	10
DNA polymerase iota isoform a (long)	22	0	0	22
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
nuclear receptor ROR-gamma isoform 1	21	0	0	21
geminin	48	0	0	48
cytochrome P450 3A4 isoform 1	20	0	0	20
lamin isoform A-delta10	36	0	0	36
Gamma-aminobutyric acid receptor subunit pi	20	3	1	24
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	1	0	9
Carbonic anhydrase 12	0	5	0	8
Carbonic anhydrase 1	0	11	0	15
Carbonic anhydrase 2	0	12	1	18
Integrin beta-3	5	1	0	6
ATP-dependent translocase ABCB1	0	11	2	14
Integrin alpha-IIb	5	1	0	6
Calmodulin-1	0	1	0	1
Androgen receptor	0	10	2	13
Pyruvate kinase PKM	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	20	3	1	24
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	20	3	1	24
Gamma-aminobutyric acid receptor subunit gamma-2	20	3	1	24
Gamma-aminobutyric acid receptor subunit alpha-5	20	3	1	24
Gamma-aminobutyric acid receptor subunit alpha-3	20	3	1	24
Gamma-aminobutyric acid receptor subunit gamma-1	20	3	1	24
Gamma-aminobutyric acid receptor subunit alpha-2	20	3	1	24
Gamma-aminobutyric acid receptor subunit alpha-4	20	3	1	24
Gamma-aminobutyric acid receptor subunit gamma-3	20	3	1	24
Gamma-aminobutyric acid receptor subunit alpha-6	20	3	1	24
Histamine H2 receptor	8	0	1	9
Xanthine dehydrogenase/oxidase	0	5	0	5
Fatty acid synthase	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-1	20	4	1	25
Gamma-aminobutyric acid receptor subunit beta-3	20	3	1	24
Gamma-aminobutyric acid receptor subunit beta-2	20	3	1	24
Cytochrome P450 1B1	0	1	0	1
Carbonic anhydrase 9	0	5	0	8
GABA theta subunit	20	3	1	24
Aurora kinase B	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	20	3	1	24
Dipeptidyl peptidase 3	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Geranylgeranyl pyrophosphate synthase	0	10	0	11
Farnesyl pyrophosphate synthase	0	15	0	15
Luciferase	13	0	0	13
cytochrome P450 family 3 subfamily A polypeptide 4	38	0	0	38
cytochrome P450 2D6	23	0	0	23
euchromatic histone-lysine N-methyltransferase 2	45	0	0	45
peripheral myelin protein 22	25	0	0	25
Albumin	0	1	6	11
Replicase polyprotein 1ab	0	5	5	10
Replicase polyprotein 1ab	0	10	5	15
Reverse transcriptase/RNaseH	0	2	3	7
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	10	0	11
RAR-related orphan receptor gamma	40	0	0	40
ATAD5 protein, partial	13	0	0	13
GLS protein	16	0	0	16
Microtubule-associated protein tau	24	0	0	24
aldehyde dehydrogenase 1 family, member A1	37	0	0	37
thyroid stimulating hormone receptor	14	0	0	14
nuclear receptor subfamily 1, group I, member 3	30	0	0	30
progesterone receptor	33	0	0	33
EWS/FLI fusion protein	35	0	0	35
retinoic acid nuclear receptor alpha variant 1	43	0	0	43
retinoid X nuclear receptor alpha	32	0	0	32
estrogen-related nuclear receptor alpha	51	0	0	51
estrogen nuclear receptor alpha	67	0	0	67
peroxisome proliferator activated receptor gamma	31	0	0	31
aryl hydrocarbon receptor	25	0	0	25
chromobox protein homolog 1	24	0	0	24
thyroid hormone receptor beta isoform 2	42	0	0	42
ATP-binding cassette sub-family C member 3	0	48	0	48
Multidrug resistance-associated protein 4	0	49	0	53
Solute carrier family 22 member 6	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	0	0	3
Bile salt export pump	0	8	0	8
Voltage-dependent calcium channel gamma-2 subunit	23	0	0	23
Bile salt export pump	0	66	0	66
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	4	0	7
Prostaglandin G/H synthase 1	0	2	1	3
Carbonic anhydrase 3	0	3	0	5
Cytochrome P450 3A4	0	14	2	19
Cytochrome P450 2D6	0	8	0	8
Cytochrome P450 2C9	0	14	0	16
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Sulfotransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	3
Glutamate receptor 2	25	1	0	26
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	6
Carbonic anhydrase 4	0	5	0	8
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	4	0	7
Carbonic anhydrase 5A, mitochondrial	0	3	0	6
Prostaglandin G/H synthase 2	0	6	1	9
Carbonic anhydrase 7	0	3	0	6
Nuclear receptor ROR-gamma	13	0	0	13
Cytochrome P450 2J2	0	7	0	7
Canalicular multispecific organic anion transporter 1	0	45	0	45
Carbonic anhydrase 15	0	3	0	5
Carbonic anhydrase 13	0	3	0	6
Carbonic anhydrase 14	0	4	0	7
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
toxin B	0	0	0	1
caspase 7, apoptosis-related cysteine protease	5	0	0	5
glucocorticoid receptor [Homo sapiens]	50	0	0	50
pregnane X nuclear receptor	42	0	0	42
vitamin D (1,25- dihydroxyvitamin D3) receptor	31	0	0	31
caspase-3	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	42	0	0	42
lethal factor (plasmid)	8	0	0	8
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Cellular tumor antigen p53	38	0	0	38
Fibroblast growth factor receptor 4	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
AR protein	62	0	0	62
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	36	0	0	36
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
heat shock protein beta-1	16	0	0	16
tumor susceptibility gene 101 protein	2	0	0	2
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
TAR DNA-binding protein 43	10	0	0	10
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	21	0	0	21
Ataxin-2	22	0	0	22
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	1	7
Proton-coupled amino acid transporter 1	0	6	0	6
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
thyroid hormone receptor beta isoform a	12	0	0	12
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	5	4	9
Androgen receptor	0	16	0	16
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	2
Guanine nucleotide-binding protein G	4	0	0	4
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	6	0	6
Farnesyl pyrophosphate synthase	0	3	0	3
interleukin 8	8	0	0	8
estrogen receptor 2 (ER beta)	21	0	0	21
IDH1	20	0	0	20
Bloom syndrome protein isoform 1	14	0	0	14
transcriptional regulator ERG isoform 3	5	0	0	5
ras-related protein Rab-9A	5	0	0	5
survival motor neuron protein isoform d	13	0	0	13
Polyphenol oxidase 2	0	2	0	3
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	3	1	4
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	2	0	2
G	31	0	0	31
Interferon beta	41	0	0	41
HLA class I histocompatibility antigen, B alpha chain	31	0	0	31
Aromatase	0	8	0	8
Amine oxidase [flavin-containing] A	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	2	0	4
Spike glycoprotein	24	0	5	29
Inositol hexakisphosphate kinase 1	31	0	0	31
cytochrome P450 2C9, partial	31	0	0	31
Chain A, Androgen receptor	0	1	0	1
Chain A, Androgen receptor	0	1	0	1
Chain A, Androgen receptor	0	1	0	1
Chain A, Androgen receptor	0	1	0	1
Chain A, Androgen receptor	0	1	0	1
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
Coagulation factor X	0	1	0	1
Prothrombin	0	5	2	7
Coagulation factor X	0	5	0	5
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Trypsin-3	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, Beta-lactamase	21	0	0	21
Chain A, HADH2 protein	21	0	0	21
Chain B, HADH2 protein	21	0	0	21
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
Chain A, Cruzipain	10	0	0	10
15-lipoxygenase, partial	14	0	0	14
phosphopantetheinyl transferase	15	0	0	15
thioredoxin glutathione reductase	9	0	0	9
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	15	0	0	15
vitamin D3 receptor isoform VDRA	22	0	0	22
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
DNA polymerase kappa isoform 1	15	0	0	15
histone acetyltransferase KAT2A isoform 1	15	0	0	15
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Trypsin	0	2	0	2
Coagulation factor VII	0	2	0	2
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	5	0	5
Tissue factor	0	3	0	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	1	2	3
10 kDa heat shock protein, mitochondrial	0	5	0	5
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Prostaglandin G/H synthase 2	0	3	0	4
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	5	0	5
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	5	0	5
10 kDa chaperonin	0	5	0	5
Solute carrier organic anion transporter family member 1B3	0	8	0	11
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	10	0	13
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
thioredoxin reductase	21	0	0	21
NFKB1 protein, partial	4	0	0	4
alpha-galactosidase	6	0	0	6
cytochrome P450 2C19 precursor	8	0	0	8
flap endonuclease 1	10	0	0	10
muscarinic acetylcholine receptor M1	11	0	0	11
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
ATP-dependent phosphofructokinase	13	0	0	13
SMAD family member 2	16	0	0	16
PPM1D protein	10	0	0	10
SMAD family member 3	16	0	0	16
GLI family zinc finger 3	38	0	0	38
farnesoid X nuclear receptor	27	0	0	27
peroxisome proliferator-activated receptor delta	24	0	0	24
nuclear receptor subfamily 1, group I, member 2	13	0	0	13
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	14	0	0	14
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	11	1	12
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	9	0	0	9
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	6	1	7
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	2	0	4
Adenosine receptor A2a	0	3	0	5
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	0	1	1
pregnane X receptor	10	0	0	10
Fumarate hydratase	10	0	0	10
Thrombopoietin	3	0	0	3
polyprotein	10	0	0	10
67.9K protein	12	0	0	12
Parkin	5	0	0	5
arylsulfatase A	9	0	0	9
thyroid stimulating hormone receptor	12	0	0	12
activating transcription factor 6	15	0	0	15
peripheral myelin protein 22 isoform 1	8	0	0	8
hemoglobin subunit beta	2	0	0	2
huntingtin isoform 2	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
Adenosine receptor A3	0	6	0	6
DNA (cytosine-5)-methyltransferase 1	0	3	0	3
Adenosine receptor A1	0	5	0	5
D(1A) dopamine receptor	3	0	0	3
Multidrug and toxin extrusion protein 1	0	9	0	9
Histone-lysine N-methyltransferase EHMT2	0	4	0	4
Chain A, Ferritin light chain	18	0	0	18
P53	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	17	0	0	17
Histone H2A.x	7	0	0	7
M-phase phosphoprotein 8	9	0	0	9
muscleblind-like protein 1 isoform 1	6	0	0	6
Protein-arginine deiminase type-4	0	3	0	3
Estrogen receptor	0	14	3	18
Estrogen receptor beta	0	11	2	13
core protein, partial	0	1	0	1
regulator of G-protein signaling 4	13	0	0	13
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	6
Glutamate receptor ionotropic, NMDA 2B	0	3	1	6
Glutamate receptor ionotropic, NMDA 2C	0	3	1	6
Glutamate receptor ionotropic, NMDA 2D	0	3	1	6
Glutamate receptor ionotropic, NMDA 3B	0	3	1	6
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	6
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	15	4	24
Glycine receptor subunit alpha-1	0	14	0	14
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	16	0	0	16
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
hypoxia-inducible factor 1 alpha subunit	13	0	0	13
TSHR protein	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	17	0	0	17
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
Alpha-synuclein	6	3	0	9
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
5-hydroxytryptamine receptor 2B	0	9	1	10
Histamine H3 receptor	0	3	2	5
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Vitamin D3 receptor	0	2	3	9
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	1	3	4
Cytochrome P450 2C19	0	11	0	12
Kappa-type opioid receptor	0	2	1	3
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	2	0	2
Vitamin D3 receptor A	0	0	2	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
D(2) dopamine receptor	0	2	1	3
Inositol monophosphatase 1	4	0	0	4
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Vpr	1	0	0	1
Albumin	0	0	4	4
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	6
Cytochrome P450 2B6	0	4	1	5
Sodium channel protein type 4 subunit alpha	0	3	0	4
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Sodium channel protein type 9 subunit alpha	0	4	0	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
DNA polymerase beta	7	0	0	7
neuropeptide S receptor isoform A	7	0	0	7
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	6	1	9
Delta-type opioid receptor	0	4	1	7
Kappa-type opioid receptor	0	6	1	9
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
thyrotropin-releasing hormone receptor	3	0	0	3
Caspase-2	0	0	1	1
Glycine receptor subunit alpha-1	0	0	4	4
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	1	3
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	2	0	2
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	2	0	2
Matrix metalloproteinase-9	0	3	0	3
Macrophage metalloelastase	0	1	0	1
nonstructural protein 1	6	0	0	6
Cytochrome P450 2C8	0	2	0	2
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent serotonin transporter	0	10	1	11
Rap guanine nucleotide exchange factor 4	2	0	0	2
P2Y purinoceptor 12	0	2	0	2
endonuclease IV	4	0	0	4
dopamine D1 receptor	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Rap guanine nucleotide exchange factor 3	6	0	0	6
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Solute carrier family 22 member 2	0	5	0	7
Plasminogen	0	1	0	1
Coagulation factor XII	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Vitamin K-dependent protein C	0	1	0	1
Serine protease hepsin	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	1	3
Multidrug and toxin extrusion protein 2	0	4	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Steryl-sulfatase	0	1	0	2
Multidrug resistance-associated protein 1	0	0	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Solute carrier organic anion transporter family member 1A3	0	1	0	5
G-protein coupled bile acid receptor 1	0	0	1	1
ATP-binding cassette sub-family C member 11	0	0	0	2
Solute carrier family 22 member 11	0	0	0	4
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
WD repeat-containing protein 5	0	5	0	5
Histone-lysine N-methyltransferase 2A	0	5	0	5
NAD(+) hydrolase SARM1	0	2	0	2
Cytosolic endo-beta-N-acetylglucosaminidase	0	4	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Glutamate receptor 1	2	1	0	3
Glutamate receptor 3	2	1	0	3
Glutamate receptor 4	2	1	0	3
Caspase-7	2	0	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier family 22 member 1	0	4	0	7
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier family 22 member 6	0	0	0	4
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	1	0	5
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Ornithine transcarbamylase, mitochondrial	0	1	0	1
Nociceptin receptor	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	3	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	2	0	2
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Oxoeicosanoid receptor 1	0	1	0	1
Capsid protein	0	1	3	4
acid sphingomyelinase	4	0	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
Sodium/bile acid cotransporter	0	3	0	3
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Carbonic anhydrase	0	2	0	4
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Glucagon-like peptide 1 receptor	0	0	1	1
Glucagon-like peptide 1 receptor	0	1	1	2
Glucagon receptor	0	0	1	1
Glucagon receptor	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	3	0	3
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	3	0	4
Plasma kallikrein	0	0	0	2
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	7	2	9
Histamine H1 receptor	0	2	3	5
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H1 receptor	0	6	2	8
Carbonic anhydrase	0	0	0	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Solute carrier family 22 member 1	0	2	0	4
Carbonic anhydrase	0	0	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	2	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	5	0	5
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	5	5
Replicase polyprotein 1ab	0	1	5	6
Transmembrane protease serine 2	0	0	5	5
Procathepsin L	0	2	5	7
Muscarinic acetylcholine receptor M2	0	8	1	10
Muscarinic acetylcholine receptor M4	0	6	0	6
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	12	1	13
Replicase polyprotein 1a	0	0	5	5
Replicase polyprotein 1ab	0	0	5	5
Muscarinic acetylcholine receptor M1	0	6	0	7
Alpha-2C adrenergic receptor	0	7	0	7
Muscarinic acetylcholine receptor M3	0	7	0	7
Alpha-1D adrenergic receptor	0	8	0	8
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	5	5
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	4	1	5
Chymotrypsinogen A	0	1	0	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Hsf1 protein	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
cytochrome P450 2D6 isoform 1	6	0	0	6
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
cytochrome P450 2C9 precursor	3	0	0	3
phosphoethanolamine/phosphocholine phosphatase isoform 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
serine/threonine-protein kinase PLK1	6	0	0	6
Sodium/potassium-transporting ATPase subunit alpha-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	3
Amyloid-beta precursor protein	1	2	0	3
Neuronal acetylcholine receptor subunit alpha-4	1	2	2	6
Microtubule-associated protein tau	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	2	2	6
Sodium/potassium-transporting ATPase subunit alpha-3	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-2	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	1	0	1	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-3	0	3	0	3
Sodium/potassium-transporting ATPase subunit gamma	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	3	0	3
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Estrogen receptor	0	2	2	5
Estrogen receptor beta	0	2	2	5
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
WRN	2	0	0	2
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
Tyrosine-protein kinase Lck	0	3	2	5
Tyrosine-protein kinase Fyn	0	2	1	3
Solute carrier family 15 member 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	2	0	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	4	0	4
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	3	0	3
Alpha-1B adrenergic receptor	0	10	0	10
Alpha-1D adrenergic receptor	0	6	0	6
Gag-Pol polyprotein	0	2	0	2
Alpha-1A adrenergic receptor	0	10	0	10
Protease	0	7	2	11
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	2	0	2
Protease	0	4	3	7
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
PINK1	2	0	0	2
Progesterone receptor	0	6	2	9
Androgen receptor	0	0	1	1
5-hydroxytryptamine receptor 1B	0	7	0	7
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Dipeptidyl peptidase 4	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	2	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	3	0	4
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	5	1	9
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Proton-coupled folate transporter	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Neuropeptide FF receptor 2	0	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	0	3
Translocator protein	0	2	1	3
ATP-dependent translocase ABCB1	0	2	0	2
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	4	0	4
Delta-type opioid receptor	0	2	0	3
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
D(1A) dopamine receptor	5	0	0	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	3	1	5
G-protein coupled receptor 55	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Platelet-activating factor receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Thromboxane-A synthase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Cathepsin L2	0	1	0	1
Cathepsin B	0	1	0	1
Pro-cathepsin H	0	1	0	1
Cathepsin S	0	1	0	1
Cruzipain	0	1	0	1
Cathepsin K	0	2	0	2
Cathepsin K	0	1	0	1
Dipeptidyl peptidase 1	0	1	0	1
Cathepsin Z	0	1	0	1
Cathepsin F	0	1	0	1
Mcl-1	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Glutathione S-transferase omega-1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Sodium-dependent noradrenaline transporter	0	4	1	5
D(3) dopamine receptor	0	10	0	10
Sodium-dependent dopamine transporter	0	4	0	4
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	4	1	5
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
SUMO-1	0	1	0	1
POsterior Segregation	0	0	1	1
chaperonin GroEL	1	0	0	1
Exoribonuclease H	0	1	0	1
Coproheme decarboxylase	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Zinc finger protein mex-5	0	0	1	1
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Pyridoxal kinase	0	0	1	2
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Gastric inhibitory polypeptide receptor	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Butyrophilin subfamily 3 member A1	0	0	2	3
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	2	0	2
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
5-hydroxytryptamine receptor 1A	0	2	3	5
Angiotensin-converting enzyme	0	4	0	4
D(2) dopamine receptor	0	5	0	5
Beta-1 adrenergic receptor	0	1	0	1
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	6	0	6
Alpha-2B adrenergic receptor	0	2	0	2
D(1A) dopamine receptor	0	4	0	4
D(4) dopamine receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Sodium-dependent dopamine transporter	0	1	1	2
5-hydroxytryptamine receptor 2A	0	6	0	6
5-hydroxytryptamine receptor 2C	0	6	0	6
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 6	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
Substance-K receptor	0	4	0	4
Thromboxane-A synthase	0	0	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Sphingosine kinase 2	0	3	0	3
Sphingosine kinase 1	0	2	0	2
Extracellular calcium-sensing receptor	0	1	0	1
Extracellular calcium-sensing receptor	0	1	0	1
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Adenine-n6-dna-methyltransferase Taqi	0	0	1	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Ermc' Methyltransferase	0	1	0	1
Chain A, Ermc' Rrna Methyltransferase	0	1	0	1
Chain A, Uroporphyrin-III C-methyltransferase	0	1	0	1
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
tRNA (cytosine(38)-C(5))-methyltransferase	0	1	1	2
Protein arginine N-methyltransferase 5	0	1	0	1
Histone-lysine N-methyltransferase SUV39H1	0	2	0	2
Adenosylhomocysteinase	0	0	0	1
Protein arginine N-methyltransferase 3	0	1	0	1
Indolethylamine N-methyltransferase	0	1	0	1
Histone-lysine N-methyltransferase NSD2	0	1	0	1
Adenosylhomocysteinase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
rRNA adenine N-6-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Histone-lysine N-methyltransferase SETDB1	0	1	0	1
Retinoblastoma-binding protein 5	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N6-adenosine-methyltransferase catalytic subunit	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Histone-lysine N-methyltransferase KMT5C	0	1	0	1
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	2	1	3
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Histone-lysine N-methyltransferase EZH1	0	1	0	1
Protein arginine N-methyltransferase 1	0	2	0	2
Methylosome protein 50	0	1	0	1
Protein dpy-30 homolog	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Histone-lysine N-methyltransferase SUV39H2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N-lysine methyltransferase SMYD2	0	1	0	1
Protein arginine N-methyltransferase 7	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Set1/Ash2 histone methyltransferase complex subunit ASH2	0	1	0	1
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Non-structural protein 1	0	1	0	1
Chain A, Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	1	1	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	1	2
Insulin receptor	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	1	1	2
DNA topoisomerase 2-alpha	0	1	1	2
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	1	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	1	2
Vascular endothelial growth factor receptor 1	0	1	0	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	1	1	2
cAMP-dependent protein kinase catalytic subunit beta	0	1	1	2
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	1	1	2
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	1	1	2
Mitogen-activated protein kinase 9	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	1	1	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	2
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	1	2
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	1	1	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	1	1	2
Protein kinase C delta type	0	1	1	2
Tyrosine-protein kinase BTK	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	1	3
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
BRCA1	1	0	0	1
Programmed cell death protein 1	0	1	0	1
Programmed cell death 1 ligand 1	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Cannabinoid receptor 1	0	1	0	1
Sulfate anion transporter 1	0	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	2	2
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Protein kinase C eta type	0	2	0	2
Protein kinase C theta type	0	2	0	2
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Phosphodiesterase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	1	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	1	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Beta-1 adrenergic receptor	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Adenylate kinase isoenzyme 1	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Envelope glycoprotein	0	0	2	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
D-alanyl-D-alanine dipeptidase	0	1	0	1
eyes absent homolog 2 isoform a	1	0	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Farnesyl diphosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	4	0	4
Matrix metalloproteinase-14	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,028)

Protein Targets (1,690)

Osteoporotic Fractures

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,028)

Drugs Studied (268)

Protein Targets (1,690)