Histiocytosis

General term for the abnormal appearance of histiocytes in the blood. Based on the pathological features of the cells involved rather than on clinical findings, the histiocytic diseases are subdivided into three groups: HISTIOCYTOSIS, LANGERHANS CELL; HISTIOCYTOSIS, NON-LANGERHANS-CELL; and HISTIOCYTIC DISORDERS, MALIGNANT.

Synonym
Histiocytosis

Excerpt	Reference
"Multicentric histiocytosis is a rare systemic disease with active episodes and prolonged periods of remission."	( Bazex, J; Gorguet, B; Grolleau-Rochiccioli, P; Laplanche, G; Manzur, F; Schmitt, AM, 1994)
"Crystal-storing histiocytosis is a rare disorder described in patients with lymphoproliferative diseases, mainly in cases of multiple myeloma but also in lymphoplasmacytic lymphoma (immunocytoma)."	( Garc-ia, JF; Lloret, E; Martín, J; Piris, MA; Sánchez, E, 1998)
"Crystal-storing histiocytosis is a rare diagnosis that to date has only been associated with 2 conditions: intracytoplasmic accumulation of crystallized immunoglobulins in patients with lymphoproliferative disorders or plasma cell dyscrasias, and histiocytic accumulations of phagocytosed clofazimine, a drug used to treat lepromatous leprosy."	( Abraham, SC; Briggs, FR; Candelora, JN; Hogan, RB; Lewis, JT, 2007)
"Crystal-storing histiocytosis is a rare disorder that is typically associated with low-grade B-cell lymphomas and monoclonal gammopathy."	( Alexiev, BA; Burke, A; Gammie, JS; Pinell-Salles, P; Sailey, CJ; Stafford, JL, 2009)
"Crystal-storing histiocytosis is a rare manifestation of plasma cell dyscrasia/monoclonal gammopathies and lymphoproliferative disorders, characterized by cytoplasmic accumulation of crystallized immunoglobulins in histiocytes."	( Almeida, LY; da Cruz Perez, DE; de Almeida, OP; de Andrade, BA; León, JE; Rizo, VH; Silva-Sousa, YT, 2012)
"Reactive histiocytosis is an uncommon, poorly understood, reactive disorder characterized by proliferation of activated, interstitial, dendritic, antigen-presenting cells associated with lymphocytes and neutrophils with a specific angiocentric orientation and occasional angioinvasion and angiodestruction."	( Cornegliani, L; Ferro, S; Gracis, M; Roccabianca, P; Vercelli, A, 2011)
"Crystal-storing histiocytosis is a rare clinical entity characterized by an increase in the number of abnormal histiocytes accompanied by accumulation of crystallized immunoglobulins."	( Beppu, K; Himeji, D; Kawano, N; Kuriyama, T; Masuyama, H; Ono, N; Oshima, K; Oyama, M; Shimao, Y; Ueda, A; Ueda, Y; Yamaguchi, K; Yamashita, K; Yoshida, S, 2013)
"Intralymphatic histiocytosis is a rare disorder associated with a variety of inflammatory conditions."	( Dolohanty, LB; Hirokawa, TI; Scott, GA; Soh, JM, 2018)
"Histiocytosis is a heterogeneous group of disease entities, comprised by two main categories, namely Langerhans and non-Langerhans cell histiocytoses."	( Foss-Skiftesvik, J; Klausen, C; Scheie, D; Sehested, A; Skjøth-Rasmussen, J, 2018)
"ALK-positive histiocytosis is a recently described entity with few reported cases in literature."	( Brousset, P; Evrard, SM; Kanoun, S; Laurent, C; Meggetto, F; Péricart, S; Syrykh, C; Ysebaert, L, 2021)
"Progressive nodular histiocytosis is a rare variant of non-Langerhans cell histiocytosis that affects the skin and mucous membranes and displays a progressive clinical course and poor response to treatment."	( Braier, J; Buján, MM; Diamond, EL; Galluzzo Mutti, ML; Sánchez La Rosa, C, 2022)
"Diagnosis of neuro-histiocytosis is challenging and relies on clinical presentation, imaging, and cerebrospinal fluid (CSF) analysis to exclude differential diagnoses."	( Audia, S; Bonnotte, B; Cohen Aubart, F; Comby, PO; Greigert, H; Haroche, J; Idbaih, A; Razanamahery, J; Samson, M, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	4 (1.89)	23.3326
1990's	47 (22.17)	12.5806
2000's	49 (23.11)	18.1394
2010's	86 (40.57)	28.8240
2020's	26 (12.26)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
choline	low	1	0
chlorine	low	1	0
salicylic acid	low	1	0
formaldehyde	low	1	0
niacinamide	low	1	0
pyrazinamide	low	1	0
phenytoin	low	1	0
alendronate	low	1	0
aspirin	low	1	0
azathioprine	low	4	0
carbamazepine	low	1	0
chlorambucil	low	1	0
chloroquine	low	1	0
clofazimine	low	4	0
fluconazole	low	1	0
flutamide	low	1	0
hydroxychloroquine	low	2	0
isoniazid	low	1	0
lomustine	low	1	0
pentoxifylline	low	1	0
sulfamethoxazole	low	1	0
thalidomide	low	5	0
prednisolone	low	8	0
prednisone	low	15	0
serine	low	1	0
carbostyril	low	1	0
colchicine	low	1	0
cytarabine	low	3	0
triamcinolone acetonide	low	2	0
methylprednisolone	low	4	0
penicillanic acid	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
pyrroles	low	2	0
pyrazines	low	2	0
nitroblue tetrazolium	low	2	0
alpha-aminopyridine	low	1	0
erythromycin	low	2	0
4-methylimidazole	low	1	0
carmine	low	1	0
streptomycin	low	1	0
molybdenum	low	1	0
aluminum chloride	low	1	0
calcium lignosulfonate	low	1	0
ozone	low	1	0
trolamine salicylate	low	10	0
cephalexin	low	1	0
tetradecanoylphorbol acetate	low	2	0
triamcinolone	low	2	0
cefazolin	low	1	0
zidovudine	low	1	0
etoposide	medium	4	1
permethrin	low	1	0
idarubicin	low	1	0
propiconazole	low	1	0
piperacillin	low	1	0
pravastatin	low	1	0
lamivudine	low	1	0
adenosine	low	1	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	medium	10	1
bendamustine hydrochloride	low	1	0
clarithromycin	low	1	0
clofarabine	low	2	0
tazobactam	low	1	0
methotrexate	low	11	0
lignin	low	1	0
lacosamide	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
bortezomib	low	4	0
fibrin	low	2	0
inositol 3-phosphate	low	2	0
tretinoin	low	1	0
tacrolimus	low	1	0
mycophenolic acid	low	1	0
leuprolide	low	1	0
quinine	low	1	0
cystine	low	1	0
cytellin	low	1	0
phenylephrine hydrochloride	low	1	0
sirolimus	low	1	0
morphine	low	1	0
technetium tc 99m diphosphonate	low	1	0
mart-1 antigen	low	1	0
crizotinib	low	2	0
dextrothyroxine	low	1	0
phytosterols	low	1	0
gdc-0973	medium	2	1
pci 32765	low	1	0
pexidartinib	low	1	0
baricitinib	low	1	0
piperidines	medium	3	1
dabrafenib	low	5	0
delgocitinib	low	1	0
tetracycline	low	1	0
pyrethrins	low	1	0
lewis x antigen	low	1	0
cyclosporine	low	7	0
muramidase	low	2	0
exudates	low	1	0
neopterin	low	1	0
rifampin	low	1	0
allopurinol	low	1	0
pyrimidinones	low	2	0

Protein Targets (1,637)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	31	0	0	31
AR protein	37	0	0	37
aldehyde dehydrogenase 1 family, member A1	23	0	0	23
geminin	38	0	0	38
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	1	3
Glutaminyl-peptide cyclotransferase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	17	0	0	17
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	37	0	0	37
nuclear receptor subfamily 1, group I, member 3	25	0	0	25
cytochrome P450 family 3 subfamily A polypeptide 4	18	0	0	18
glucocorticoid receptor [Homo sapiens]	35	0	0	35
estrogen-related nuclear receptor alpha	38	0	0	38
pregnane X nuclear receptor	28	0	0	28
estrogen nuclear receptor alpha	47	0	0	47
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
heat shock protein beta-1	9	0	0	9
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
lamin isoform A-delta10	26	0	0	26
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Bile salt export pump	0	46	0	46
Cyclin-dependent kinase 1	0	2	9	11
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	21	1	0	22
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	9	0	0	9
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	1	3
ATPase family AAA domain-containing protein 5	22	0	0	22
Ataxin-2	26	0	0	26
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	6	0	0	6
retinoid X nuclear receptor alpha	27	0	0	27
NPYLR7B	0	0	2	2
arylsulfatase A	9	0	0	9
IDH1	13	0	0	13
Histone H2A.x	15	0	0	15
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
mitogen-activated protein kinase 1	10	0	0	10
flap endonuclease 1	10	0	0	10
nuclear receptor ROR-gamma isoform 1	17	0	0	17
peripheral myelin protein 22	19	0	0	19
survival motor neuron protein isoform d	18	0	0	18
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	8	10	18
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	4	2	6
Insulin receptor	0	1	9	11
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	2	3
Platelet-derived growth factor receptor beta	0	3	9	13
Adenosine receptor A3	0	6	2	9
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	1	9	11
Inosine-5'-monophosphate dehydrogenase 2	0	3	9	12
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	3	0	3
Fibroblast growth factor receptor 2	0	0	1	2
Fibroblast growth factor receptor 4	0	0	1	2
Fibroblast growth factor receptor 3	0	1	1	3
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	2	1	3
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	1	3	5
Adenosine receptor A2b	0	1	1	3
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	2	2	5
Adenosine receptor A2a	0	2	1	3
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	3	0	4
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	8	9
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	3	0	4
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	3	0	4
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	3	1	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Acetylcholinesterase	0	4	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
Farnesyl pyrophosphate synthase	0	1	0	1
interleukin 8	10	0	0	10
thyroid stimulating hormone receptor	11	0	0	11
estrogen receptor 2 (ER beta)	15	0	0	15
progesterone receptor	17	0	0	17
euchromatic histone-lysine N-methyltransferase 2	34	0	0	34
Bloom syndrome protein isoform 1	12	0	0	12
transcriptional regulator ERG isoform 3	6	0	0	6
thyroid hormone receptor beta isoform 2	28	0	0	28
ras-related protein Rab-9A	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	31	0	0	31
ATP-binding cassette sub-family C member 3	0	37	0	37
Multidrug resistance-associated protein 4	0	37	0	39
Polyphenol oxidase 2	0	3	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	28	0	0	28
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	2	2
Canalicular multispecific organic anion transporter 1	0	38	0	39
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	2
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
thyroid stimulating hormone receptor	12	0	0	12
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	2	0	2
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	3
Tyrosine-protein kinase	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
acetylcholinesterase	7	0	0	7
phosphopantetheinyl transferase	15	0	0	15
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
SMAD family member 2	8	0	0	8
ATAD5 protein, partial	11	0	0	11
Fumarate hydratase	12	0	0	12
USP1 protein, partial	15	0	0	15
NFKB1 protein, partial	4	0	0	4
PPM1D protein	11	0	0	11
SMAD family member 3	8	0	0	8
Thrombopoietin	4	0	0	4
caspase 7, apoptosis-related cysteine protease	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
EWS/FLI fusion protein	24	0	0	24
farnesoid X nuclear receptor	19	0	0	19
G	14	0	0	14
cytochrome P450 2D6	12	0	0	12
polyprotein	12	0	0	12
peroxisome proliferator-activated receptor delta	19	0	0	19
peroxisome proliferator activated receptor gamma	18	0	0	18
caspase-3	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	9	0	0	9
cytochrome P450 2D6 isoform 1	4	0	0	4
cellular tumor antigen p53 isoform a	6	0	0	6
cytochrome P450 2C9 precursor	4	0	0	4
D(1A) dopamine receptor	3	0	0	3
chromobox protein homolog 1	20	0	0	20
thyroid hormone receptor beta isoform a	12	0	0	12
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
huntingtin isoform 2	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
cytochrome P450 3A4 isoform 1	12	0	0	12
muscarinic acetylcholine receptor M1	11	0	0	11
lethal factor (plasmid)	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	12	1	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	3	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 4	0	2	0	2
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	24	0	0	24
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Thyroid hormone receptor alpha	0	2	0	2
Integrin beta-3	4	1	0	5
Tyrosine-protein kinase Fyn	0	3	9	12
ATP-dependent translocase ABCB1	0	7	0	7
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M4	0	4	0	4
ATP-dependent translocase ABCB1	0	15	2	20
Integrin alpha-IIb	4	1	0	5
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	4	0	4
Alpha-2A adrenergic receptor	0	4	1	5
Cytochrome P450 2C8	0	3	0	4
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	7	0	7
Gamma-aminobutyric acid receptor subunit beta-1	12	1	0	13
Alpha-1B adrenergic receptor	0	5	0	5
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	4	0	4
Thyroid hormone receptor beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	12	1	0	13
Gamma-aminobutyric acid receptor subunit gamma-2	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-5	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-3	12	1	0	13
Muscarinic acetylcholine receptor M3	0	4	0	4
ATP-dependent translocase ABCB1	0	7	0	7
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-2	12	1	0	13
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Histamine H2 receptor	0	2	0	2
Endothelin-1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	12	1	0	13
Gamma-aminobutyric acid receptor subunit gamma-3	12	1	0	13
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	12	1	0	13
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	4	1	6
D(3) dopamine receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	5
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	4	1	6
5-hydroxytryptamine receptor 2B	0	4	0	4
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	5	0	5
Histamine H2 receptor	6	0	0	6
D(1A) dopamine receptor	3	0	0	3
5-hydroxytryptamine receptor 6	0	4	0	4
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	16	1	2	19
Gamma-aminobutyric acid receptor subunit alpha-1	12	2	0	14
Gamma-aminobutyric acid receptor subunit beta-3	12	1	0	13
Gamma-aminobutyric acid receptor subunit beta-2	12	1	0	13
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Sodium channel protein type 5 subunit alpha	0	3	0	3
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	5	0	5
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	12	1	0	13
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	14	0	0	14
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	5	1	6
Gamma-aminobutyric acid receptor subunit epsilon	12	1	0	13
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
cytochrome P450 2C9, partial	14	0	0	14
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thioredoxin reductase	22	0	0	22
GLS protein	9	0	0	9
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	4	0	0	4
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	13	0	0	13
DNA polymerase kappa isoform 1	10	0	0	10
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	6	0	7
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 1	0	9	0	9
Carbonic anhydrase 2	0	9	1	10
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	5	1	6
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	9	1	1	11
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, Ferritin light chain	9	0	0	9
GLI family zinc finger 3	31	0	0	31
Microtubule-associated protein tau	14	0	0	14
thioredoxin glutathione reductase	8	0	0	8
P53	1	0	0	1
aryl hydrocarbon receptor	15	0	0	15
activating transcription factor 6	9	0	0	9
peripheral myelin protein 22 isoform 1	10	0	0	10
hemoglobin subunit beta	3	0	0	3
M-phase phosphoprotein 8	7	0	0	7
muscleblind-like protein 1 isoform 1	10	0	0	10
Bile salt export pump	0	9	0	9
Protein-arginine deiminase type-4	0	6	0	6
Bone morphogenetic protein receptor type-1B	0	0	9	9
Membrane-associated progesterone receptor component 1	0	0	7	7
Serine/threonine-protein kinase PLK4	0	0	9	9
ATP-dependent RNA helicase DDX3X	0	0	9	9
Pyridoxal kinase	0	0	9	9
Citron Rho-interacting kinase	0	0	9	9
Serine/threonine-protein kinase Chk1	0	0	9	9
Aurora kinase A	0	0	9	9
Cyclin-G-associated kinase	0	1	9	10
Ephrin type-B receptor 6	0	0	9	9
Peroxisomal acyl-coenzyme A oxidase 3	0	0	9	9
Receptor-interacting serine/threonine-protein kinase 2	0	1	9	10
Dynamin-like 120 kDa protein, mitochondrial	0	0	9	9
Tyrosine-protein kinase JAK2	0	5	5	11
Eukaryotic translation initiation factor 5B	0	0	6	6
Rho-associated protein kinase 2	0	0	9	9
Serine/threonine-protein kinase ULK1	0	0	9	9
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	9	9
Ribosomal protein S6 kinase alpha-5	0	0	9	9
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	9	9
Ribosomal protein S6 kinase alpha-4	0	0	9	9
Serine/threonine-protein kinase 16	0	0	9	9
Serine/threonine-protein kinase 10	0	0	9	9
Serine/threonine-protein kinase D3	0	0	10	10
Structural maintenance of chromosomes protein 2	0	0	9	9
Mitogen-activated protein kinase kinase kinase 6	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	9	9
Serine/threonine-protein kinase LATS1	0	0	9	9
Serine/threonine-protein kinase PAK 4	0	0	9	9
Tyrosine-protein kinase ABL1	0	1	10	11
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	7	7
ADP/ATP translocase 2	0	0	9	9
Protein kinase C beta type	0	2	10	12
Tyrosine-protein kinase Lck	0	3	9	12
Glycogen phosphorylase, liver form	0	0	9	9
Tyrosine-protein kinase Fes/Fps	0	0	9	9
Adenine phosphoribosyltransferase	0	0	7	7
Tyrosine-protein kinase Yes	0	1	9	10
Tyrosine-protein kinase Lyn	0	1	9	10
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	9	11
Insulin-like growth factor 1 receptor	0	1	9	10
Signal recognition particle receptor subunit alpha	0	0	8	8
Cytochrome c1, heme protein, mitochondrial	0	0	9	9
Hepatocyte growth factor receptor	0	3	9	12
Tyrosine-protein kinase HCK	0	1	9	10
Serine/threonine-protein kinase A-Raf	0	2	9	11
Glycogen phosphorylase, brain form	0	0	9	9
Breakpoint cluster region protein	0	0	9	9
Serine/threonine-protein kinase pim-1	0	1	9	10
DNA topoisomerase 2-alpha	0	1	10	16
Cyclin-dependent kinase 4	0	0	9	9
ADP/ATP translocase 3	0	0	9	9
Proto-oncogene tyrosine-protein kinase Src	0	2	9	11
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	9	9
Serine/threonine-protein kinase B-raf	0	3	11	16
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	9	9
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	9	10
Tyrosine-protein kinase Fer	0	0	9	9
Protein kinase C alpha type	0	1	10	11
cAMP-dependent protein kinase catalytic subunit alpha	0	0	9	9
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	9	9
Casein kinase II subunit alpha'	0	0	9	9
Ras-related protein Rab-6A	0	0	9	9
Ephrin type-A receptor 1	0	0	9	9
Multifunctional protein ADE2	0	0	9	9
cAMP-dependent protein kinase catalytic subunit gamma	0	0	7	7
cAMP-dependent protein kinase catalytic subunit beta	0	0	9	9
Ferrochelatase, mitochondrial	0	0	10	10
Ribosomal protein S6 kinase beta-1	0	1	8	9
Tyrosine-protein kinase JAK1	0	5	9	15
Cyclin-dependent kinase 2	0	1	10	11
Beta-adrenergic receptor kinase 1	0	0	9	9
Probable ATP-dependent RNA helicase DDX6	0	0	9	9
Mitogen-activated protein kinase 3	0	0	9	9
MAP/microtubule affinity-regulating kinase 3	0	0	9	9
Deoxycytidine kinase	0	0	9	11
Mitogen-activated protein kinase 1	0	1	9	10
Ephrin type-A receptor 2	0	2	9	11
Ephrin type-B receptor 2	0	1	9	10
Non-receptor tyrosine-protein kinase TYK2	0	3	9	13
UMP-CMP kinase	0	0	6	6
Phosphatidylethanolamine-binding protein 1	0	0	8	8
Wee1-like protein kinase	0	0	9	9
Heme oxygenase 2	0	0	9	9
S-adenosylmethionine synthase isoform type-2	0	0	8	8
DnaJ homolog subfamily A member 1	0	0	9	9
RAC-alpha serine/threonine-protein kinase	0	0	9	9
RAC-beta serine/threonine-protein kinase	0	1	9	10
DNA replication licensing factor MCM4	0	0	9	9
Myosin-10	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 2	0	5	9	14
Receptor-type tyrosine-protein kinase FLT3	0	4	9	13
Bone morphogenetic protein receptor type-1A	0	0	9	9
Activin receptor type-1B	0	0	9	9
TGF-beta receptor type-1	0	1	9	10
Serine/threonine-protein kinase receptor R3	0	0	5	5
TGF-beta receptor type-2	0	0	9	9
Electron transfer flavoprotein subunit beta	0	0	7	7
Tyrosine-protein kinase CSK	0	1	9	10
Glycine--tRNA ligase	0	0	9	9
Protein kinase C iota type	0	0	10	10
Exosome RNA helicase MTR4	0	0	9	9
Tyrosine-protein kinase Tec	0	1	9	10
Tyrosine-protein kinase ABL2	0	0	9	9
Tyrosine-protein kinase FRK	0	1	9	10
G protein-coupled receptor kinase 6	0	0	7	7
Tyrosine-protein kinase SYK	0	1	9	10
26S proteasome regulatory subunit 6B	0	1	9	10
Mitogen-activated protein kinase 8	0	0	9	9
Mitogen-activated protein kinase 9	0	0	9	9
Dual specificity mitogen-activated protein kinase kinase 3	0	0	9	9
Casein kinase I isoform alpha	0	0	8	8
Casein kinase I isoform delta	0	0	9	9
MAP kinase-activated protein kinase 2	0	0	9	9
Elongation factor Tu, mitochondrial	0	0	9	9
Cysteine--tRNA ligase, cytoplasmic	0	0	8	8
Casein kinase I isoform epsilon	0	0	9	9
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	9	9
Dual specificity protein kinase CLK1	0	0	9	9
Dual specificity protein kinase CLK2	0	0	9	9
Dual specificity protein kinase CLK3	0	0	5	5
Glycogen synthase kinase-3 alpha	0	0	9	9
Glycogen synthase kinase-3 beta	0	0	9	9
Cyclin-dependent kinase 7	0	1	9	10
Cyclin-dependent kinase 9	0	0	9	9
Ras-related protein Rab-27A	0	0	9	9
Interleukin-1 receptor-associated kinase 1	0	0	9	9
Ribosomal protein S6 kinase alpha-3	0	0	9	9
Serine/threonine-protein kinase Nek2	0	0	9	9
Serine/threonine-protein kinase Nek3	0	0	9	9
Tyrosine-protein kinase JAK3	0	4	2	7
Dual specificity mitogen-activated protein kinase kinase 6	0	0	9	9
LIM domain kinase 1	0	0	9	9
LIM domain kinase 2	0	0	9	9
Mitogen-activated protein kinase 10	0	0	9	9
Tyrosine--tRNA ligase, cytoplasmic	0	0	9	9
5'-AMP-activated protein kinase subunit gamma-1	0	0	9	10
Ephrin type-B receptor 3	0	0	9	9
Ephrin type-A receptor 5	0	0	9	9
Ephrin type-B receptor 4	0	1	9	10
Ephrin type-A receptor 4	0	0	9	9
Adenylate kinase 2, mitochondrial	0	0	9	9
Ras-related protein Rab-10	0	0	9	9
Actin-related protein 3	0	1	9	10
Actin-related protein 2	0	0	8	8
GTP-binding nuclear protein Ran	0	0	9	9
Casein kinase I isoform gamma-2	0	0	9	9
Cyclin-dependent kinase 3	0	0	7	7
Cyclin-dependent kinase 6	0	0	9	9
Cyclin-dependent-like kinase 5	0	0	9	9
Cyclin-dependent kinase 16	0	0	9	9
Cyclin-dependent kinase 17	0	0	9	9
ATP-dependent 6-phosphofructokinase, platelet type	0	0	8	8
Dual specificity mitogen-activated protein kinase kinase 1	0	4	9	13
DNA topoisomerase 2-beta	0	1	10	17
Protein kinase C theta type	0	0	10	10
Activin receptor type-1	0	0	9	9
Macrophage-stimulating protein receptor	0	1	9	10
Focal adhesion kinase 1	0	0	9	9
Protein kinase C delta type	0	1	10	11
Tyrosine-protein kinase BTK	0	3	10	13
Activated CDC42 kinase 1	0	0	9	9
Epithelial discoidin domain-containing receptor 1	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	9	9
Serine/threonine-protein kinase 4	0	0	9	9
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	9	10
Dual specificity mitogen-activated protein kinase kinase 5	0	0	9	9
Mitogen-activated protein kinase 7	0	0	9	9
Serine/threonine-protein kinase PAK 2	0	0	8	8
Serine/threonine-protein kinase 3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 1	0	0	9	9
Integrin-linked protein kinase	0	0	9	9
Rho-associated protein kinase 1	0	0	9	9
Non-receptor tyrosine-protein kinase TNK1	0	0	9	9
Serine/threonine-protein kinase ATR	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	9	9
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	9	9
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	9	9
Activin receptor type-2B	0	0	9	9
Bone morphogenetic protein receptor type-2	0	0	9	9
Protein-tyrosine kinase 6	0	1	9	10
cGMP-dependent protein kinase 1	0	0	9	9
Cyclin-dependent kinase 13	0	0	9	9
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	9	9
Protein-tyrosine kinase 2-beta	0	0	9	9
Maternal embryonic leucine zipper kinase	0	0	9	9
Structural maintenance of chromosomes protein 1A	0	0	9	9
Chromodomain-helicase-DNA-binding protein 4	0	0	9	9
Peroxisomal acyl-coenzyme A oxidase 1	0	0	8	8
Ephrin type-A receptor 7	0	0	7	7
Delta(24)-sterol reductase	0	0	9	9
Ribosomal protein S6 kinase alpha-1	0	1	9	10
Dual specificity testis-specific protein kinase 1	0	0	7	7
Myosin light chain kinase, smooth muscle	0	0	9	9
Mitogen-activated protein kinase 11	0	0	9	9
Serine/threonine-protein kinase STK11	0	0	9	9
Serine/threonine-protein kinase N1	0	0	9	9
Serine/threonine-protein kinase N2	0	1	9	10
Mitogen-activated protein kinase 14	0	1	9	10
Calcium/calmodulin-dependent protein kinase type IV	0	0	9	9
Mitogen-activated protein kinase kinase kinase 11	0	0	9	9
MAP kinase-activated protein kinase 3	0	0	6	6
Discoidin domain-containing receptor 2	0	0	9	9
AP2-associated protein kinase 1	0	1	9	10
Myosin light chain kinase 3	0	0	9	9
Uncharacterized aarF domain-containing protein kinase 5	0	0	6	6
Putative heat shock protein HSP 90-beta 2	0	0	9	9
Rab-like protein 3	0	0	8	8
Serine/threonine-protein kinase MRCK alpha	0	0	9	9
Serine/threonine-protein kinase MRCK gamma	0	0	8	8
Acyl-CoA dehydrogenase family member 10	0	0	9	9
Serine/threonine-protein kinase ULK3	0	0	9	9
Uncharacterized protein FLJ45252	0	0	9	9
Acyl-CoA dehydrogenase family member 11	0	0	9	9
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	9	9
Serine/threonine-protein kinase MARK2	0	0	9	9
ATP-dependent RNA helicase DHX30	0	0	8	8
Serine/threonine-protein kinase TAO1	0	0	9	9
STE20-related kinase adapter protein alpha	0	0	9	9
Myosin-14	0	0	8	8
AarF domain-containing protein kinase 1	0	0	9	9
ATP-dependent RNA helicase DDX42	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 3	0	1	9	10
MAP kinase-activated protein kinase 5	0	0	9	9
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	4	4
Misshapen-like kinase 1	0	0	7	7
Atypical kinase COQ8A, mitochondrial	0	0	9	9
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	9	9
Mitogen-activated protein kinase 15	0	0	9	9
Serine/threonine-protein kinase Nek9	0	0	9	9
ATP-dependent RNA helicase DDX1	0	0	9	9
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	9	9
Aurora kinase B	0	1	9	10
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Serine/threonine-protein kinase Nek1	0	0	9	9
PAS domain-containing serine/threonine-protein kinase	0	0	7	7
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	9	9
EKC/KEOPS complex subunit TP53RK	0	0	9	9
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	9	9
Mitogen-activated protein kinase kinase kinase 5	0	0	9	9
Mitogen-activated protein kinase kinase kinase 3	0	0	9	9
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	9	9
Nucleolar GTP-binding protein 1	0	0	9	9
Serine/threonine-protein kinase D2	0	0	9	9
NUAK family SNF1-like kinase 2	0	0	7	7
RNA cytidine acetyltransferase	0	0	9	9
Serine/threonine-protein kinase SIK2	0	0	9	9
STE20-like serine/threonine-protein kinase	0	0	9	9
Serine/threonine-protein kinase TAO3	0	0	9	9
dCTP pyrophosphatase 1	0	0	9	9
Dual specificity protein kinase CLK4	0	0	9	9
Casein kinase I isoform gamma-1	0	0	9	9
Serine/threonine-protein kinase PAK 6	0	0	6	6
Phenylalanine--tRNA ligase beta subunit	0	0	9	9
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
BMP-2-inducible protein kinase	0	0	9	9
Obg-like ATPase 1	0	0	7	7
Midasin	0	0	9	9
Interleukin-1 receptor-associated kinase 4	0	0	9	9
Mitogen-activated protein kinase kinase kinase 20	0	1	9	10
Cyclin-dependent kinase 12	0	0	9	9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	8	8
Serine/threonine-protein kinase 26	0	0	9	9
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	8	8
Serine/threonine-protein kinase NLK	0	0	9	9
5'-AMP-activated protein kinase subunit gamma-2	0	0	9	10
Serine/threonine-protein kinase TBK1	0	0	9	9
Septin-9	0	0	9	9
Ribosomal protein S6 kinase alpha-6	0	0	9	9
TRAF2 and NCK-interacting protein kinase	0	0	9	9
Serine/threonine-protein kinase TAO2	0	0	9	9
Long-chain-fatty-acid--CoA ligase 5	0	0	5	5
Serine/threonine-protein kinase ICK	0	0	9	9
RAC-gamma serine/threonine-protein kinase	0	0	9	9
Serine/threonine-protein kinase 38-like	0	0	5	5
Serine/threonine-protein kinase SIK3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 2	0	0	9	9
Thyroid hormone receptor-associated protein 3	0	0	8	8
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	9	9
Receptor-interacting serine/threonine-protein kinase 3	0	1	9	10
Serine/threonine-protein kinase MRCK beta	0	0	9	9
Interleukin-1 receptor-associated kinase 3	0	0	9	9
Serine/threonine-protein kinase 24	0	0	8	8
Casein kinase I isoform gamma-3	0	0	9	9
Mitogen-activated protein kinase kinase kinase 4	0	0	9	9
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	19	0	0	19
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
Caspase-7	5	0	0	5
caspase-3	5	0	0	5
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	2	0	2
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	5	0	5
Prothrombin	0	1	0	2
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	4	0	4
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	5	0	5
Carbonic anhydrase 6	0	4	0	4
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	4	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	4	0	4
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	2	0	2
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	5	0	5
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	3	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	2	0	2
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	4	0	4
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Carbonic anhydrase 14	0	4	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	0	4
Chain A, Beta-lactamase	8	0	0	8
Vpr	3	0	0	3
Albumin	0	0	1	1
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2C9	0	9	1	11
UDP-glucuronosyltransferase 2B7	0	0	0	3
Cytochrome P450 2B6	0	2	2	5
Cytochrome P450 2J2	0	4	0	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Chain A, serum paraoxonase	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Luciferase	8	0	0	8
67.9K protein	13	0	0	13
luciferase	1	0	0	1
eyes absent homolog 2 isoform a	3	0	0	3
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Glutamate receptor 1	2	1	0	3
Glutamate receptor 3	2	1	0	3
Glutamate receptor 4	2	1	0	3
Tyrosine-protein phosphatase 1	0	1	0	1
Alpha-synuclein	4	3	0	7
Inositol monophosphatase 1	4	0	0	4
C-terminal-binding protein 1	2	0	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Smad3	7	0	0	7
apical membrane antigen 1, AMA1	4	0	0	4
vitamin D3 receptor isoform VDRA	10	0	0	10
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 22 member 6	0	3	0	5
Solute carrier family 22 member 8	0	3	0	6
Solute carrier family 22 member 11	0	2	0	5
Solute carrier family 22 member 8	0	3	0	4
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
Solute carrier family 15 member 1	0	1	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 15 member 2	0	1	0	2
GALC protein	2	0	0	2
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Cytochrome P450 2D6	0	4	1	5
Solute carrier organic anion transporter family member 1B3	0	9	0	11
Carbonic anhydrase	0	1	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Amyloid-beta precursor protein	2	2	0	4
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	1	2	3
Cytochrome P450 3A4	0	14	2	17
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	2	2	4
Alpha-2C adrenergic receptor	0	2	0	2
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	3	2	5
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	1	0	3
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	3	0	5
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
glp-1 receptor, partial	9	0	0	9
tyrosine-protein kinase Yes	5	0	0	5
relaxin receptor 1 isoform 1	2	0	0	2
bcl-2-like protein 11 isoform 1	0	0	2	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Rap guanine nucleotide exchange factor 4	1	0	0	1
streptokinase A precursor	0	0	3	3
Solute carrier organic anion transporter family member 1B1	0	7	0	9
mitogen-activated protein kinase kinase kinase kinase 2 isoform 1	0	0	1	1
mitogen-activated protein kinase kinase kinase 3 isoform 1	0	0	1	1
Estrogen receptor	0	0	1	1
5-hydroxytryptamine receptor 1A	0	3	1	4
Cruzipain	0	1	0	1
Estrogen receptor beta	0	0	1	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	5
endonuclease IV	9	0	0	9
PAX8	0	0	0	1
pregnane X receptor	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C19 precursor	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
neuropeptide S receptor isoform A	2	0	0	2
Solute carrier family 22 member 3	0	2	0	2
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	3	0	3
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
dopamine D1 receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	12	2	19
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	12	0	12
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Leukotriene C4 synthase	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	8	8
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	5	5
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Sodium-dependent phosphate transport protein 2B	0	1	0	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Tyrosine-protein kinase ABL1	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	2	6
HLA class II histocompatibility antigen gamma chain	0	1	0	1
High affinity nerve growth factor receptor	0	1	8	9
Nucleophosmin	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	3	1	4
Proto-oncogene tyrosine-protein kinase ROS	0	2	1	3
Tyrosine-protein kinase Fgr	0	2	5	7
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Androgen receptor	0	5	0	5
Mast/stem cell growth factor receptor Kit	0	1	1	2
Insulin receptor-related protein	0	0	1	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	2	1	3
Vascular endothelial growth factor receptor 1	0	1	1	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	1	2
Protein kinase C eta type	0	0	2	2
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	6	6
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Vascular endothelial growth factor receptor 2	0	3	1	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase ZAP-70	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	8	8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	6	6
Tyrosine-protein kinase Blk	0	1	2	3
Cytoplasmic tyrosine-protein kinase BMX	0	3	2	5
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	7	7
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
ALK tyrosine kinase receptor	0	1	0	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	2	2	4
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Angiopoietin-1 receptor	0	1	0	1
Tyrosine-protein kinase receptor TYRO3	0	1	1	2
Cyclin-dependent kinase 18	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	1	6	7
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Lysine--tRNA ligase	0	1	0	1
Cyclin-dependent kinase 10	0	0	4	4
Serine/threonine-protein kinase D1	0	1	2	3
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	1	1	2
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Sigma intracellular receptor 2	0	2	0	2
Macrophage-stimulating protein receptor	0	1	0	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	6	6
Dual serine/threonine and tyrosine protein kinase	0	1	1	2
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Mixed lineage kinase domain-like protein	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	4	4
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	8	8
Cyclin-dependent kinase 15	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	6	6
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Echinoderm microtubule-associated protein-like 4	0	1	0	1
Serine/threonine-protein kinase Nek6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Aurora kinase A-interacting protein	0	1	0	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	5	5
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	3	3	6
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	6	6
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	4
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	3	0	4
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Pirin	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
GTPase KRas	0	2	0	2
Heat shock factor protein 1	0	2	0	2
Protein kinase C zeta type	0	0	4	4
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Trace amine-associated receptor 1	0	0	1	1
Chain A, Cruzipain	3	0	0	3
nonstructural protein 1	7	0	0	7
DNA polymerase beta	3	0	0	3
Motilin receptor	0	0	1	1
acid sphingomyelinase	2	0	0	2
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
Albumin	0	1	5	6
60 kDa chaperonin	0	2	0	2
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
10 kDa heat shock protein, mitochondrial	0	3	0	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Cytochrome P450 1B1	0	1	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	3	1	4
50S ribosomal protein L36 2	0	2	1	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
DNA topoisomerase 2	0	0	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Integrase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Solute carrier family 22 member 8	0	0	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
15-lipoxygenase, partial	4	0	0	4
alpha-galactosidase	2	0	0	2
Cocaine esterase	0	1	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Genome polyprotein	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Proton-coupled amino acid transporter 1	0	2	0	2
Amino acid transporter	0	2	0	2
DNA polymerase III, partial	1	0	0	1
Parkin	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
glucokinase regulatory protein	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Cytochrome P450 1A2	0	2	1	3
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Cytochrome P450 2C19	0	3	1	5
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Hsf1 protein	0	0	1	1
Capsid protein	0	1	1	2
Reverse transcriptase/RNaseH	0	1	3	7
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Delta-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	7
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	4
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	1	0	2
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
G1/S-specific cyclin-E1	0	1	0	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Peroxiredoxin-like 2A	0	1	0	1
Platelet glycoprotein VI	0	1	0	1
vasopressin V1b receptor	1	0	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Cholinesterase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Chitotriosidase-1	0	2	1	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Endochitinase B1	0	2	1	3
serine-protein kinase ATM isoform a	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	2	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase SHV-1	0	2	0	3
Beta-lactamase	0	1	0	2
Beta-lactamase OXA-7	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	3
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Insulin receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier family 22 member 7	0	1	0	3
Solute carrier family 22 member 7	0	1	0	3
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Guanine nucleotide-binding protein G	1	0	0	1
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Cholinesterase	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protease	0	2	2	4
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase OXA-1	0	1	0	2
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase TEM	0	2	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (212)

Protein Targets (1,637)

Histiocytosis

Synonyms(1)

Research Excerpts

Overview

Research

Studies (212)

Drugs Studied (124)

Protein Targets (1,637)