E chaffeensis Infection

A tick-borne disease characterized by FEVER; HEADACHE; myalgias; ANOREXIA; and occasionally RASH. It is caused by several bacterial species and can produce disease in DOGS; CATTLE; SHEEP; GOATS; HORSES; and humans. The primary species causing human disease are EHRLICHIA CHAFFEENSIS; ANAPLASMA PHAGOCYTOPHILUM; and Ehrlichia ewingii.

Synonym
E. ewingii Infection
Ehrlichia chaffeensis Infection
Ehrlichia ewingii Infection
Ehrlichiosis
Human Ehrlichiosis
E chaffeensis Infection
Ehrlichia Infection
E ewingii Infection
E. chaffeensis Infection

Excerpt	Reference
"Human ehrlichiosis is a recently recognized rickettsial disease."	( Brouqui, P; Delmont, J; Faugere, B; Gondao, L; Kelly, PJ; Laurens, R; Le Cam, C; Sawadogo, S; Tounkara, A, 1994)
"Human ehrlichiosis is transmitted by ticks."	( Augustyniak, K; Gladysz, A; Inglot, M; Knysz, B, 1995)
"Human monocytic ehrlichiosis is caused by Ehrlichia chaffeensis, an intracellular bacterium probably transmitted by the tick Amblyomma americanum in the United States."	( Brouqui, P; Lecam, C; Olson, J; Raoult, D, 1994)
"Human ehrlichiosis is a newly emergent, tick-borne, zoonotic infection caused by members of the genus Ehrlichia."	( Weinstein, RS, 1996)
"Human ehrlichiosis is a zoonotic disease, caused by a rickettsia that infects leukocytes."	( Anderson, BE; Arraga-Alvarado, C; Bernardoni, A; Montero-Ojeda, M; Parra, O, 1996)
"Human ehrlichiosis is not a common cause of acute respiratory distress syndrome (ARDS)."	( Byrd, MA; Patel, RG, 1999)
"Ehrlichiosis is an emerging zoonotic disease transmitted to man by ticks."	( Potasman, I; Zikonov, I, 1999)
"Human monocytic ehrlichiosis is an emerging tick-borne disease caused by the rickettsia Ehrlichia chaffeensis."	( Chapes, SK; Cheng, C; Ganta, RR; Rokey, AM; Wilkerson, MJ, 2002)
"Human granulocytic ehrlichiosis is an emerging infectious disease, which is transmitted by the tick Ixodes ricinus in Europe, like other diseases: Lyme disease, tick-borne encephalitis, babesiosis."	( Abadia, G; Amiel, C; Choudat, D, 2004)
"Once an ehrlichiosis is suspected on historical and clinical grounds, doxycycline treatment should be initiated concurrently with attempts at etiologic confirmation using laboratory methods such as blood smear examination, polymerase chain reaction, culture, and serologic tests."	( Bakken, JS; Dumler, JS; Madigan, JE; Pusterla, N, 2007)
"Human monocytic ehrlichiosis is one of the most prevalent tick-borne zoonoses caused by infection with Ehrlichia chaffeensis."	( Cheng, Z; Matsuo, J; Rahman, MA; Rikihisa, Y, 2012)
"Anaplasmosis and ehrlichiosis are of serious health concern worldwide for animals and humans."	( AbuBakar, S; Lim, YA; Low, VL; Prakash, BK; Sofian-Azirun, M; Tan, TK; Vinnie-Siow, WY, 2018)
"Canine ehrlichiosis is a very important emerging disease in India."	( Das, M; Dubey, R; Kukreti, K; Pandey, L; Rastogi, A; Sharma, P, 2018)

Excerpt	Reference
"Most human cases of ehrlichiosis have been diagnosed in the USA."	( Brouqui, P; Delmont, J; Faugere, B; Gondao, L; Kelly, PJ; Laurens, R; Le Cam, C; Sawadogo, S; Tounkara, A, 1994)
"Granulocytic ehrlichiosis has previously been associated with anemia, thrombocytopenia, and polyarthritis in dogs."	( Fisher, DJ; Greene, CE; Maretzki, CH, 1994)

Excerpt	Reference
"Forty-three dogs with canine ehrlichiosis were treated with long-acting oxytetracycline (TLA) at a dose of 20 mg/kg."	( Abdullah, SU; Adawa, DA; Adeyanju, JB; Hassan, AZ; Ogunkoya, AB; Okoro, JE, 1992)
"Human granulocytic ehrlichiosis did not seem to present in a fulminant fashion, and all treated patients had excellent responses to rifampin or doxycycline therapy."	( Aguero-Rosenfeld, M; Dhand, A; Haddad, FA; Horowitz, HW; Nadelman, RB; Stokes, DP, 2007)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	62 (27.07)	12.5806
2000's	77 (33.62)	18.1394
2010's	77 (33.62)	28.8240
2020's	13 (5.68)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	2	0
cadaverine	low	2	0
chlorine	low	1	0
lactic acid	low	1	0
histamine	low	1	0
inositol	low	1	0
nitrites	low	1	0
purine	low	1	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
antipyrine	low	1	0
aspirin	low	1	0
bethanechol	low	1	0
verapamil	low	1	0
ciprofloxacin	low	1	0
deferoxamine	low	3	0
fipronil	medium	6	3
ethidium	low	1	0
indomethacin	low	1	0
ketamine	low	1	0
monodansylcadaverine	low	2	0
pimobendan	low	1	0
xylazine	low	1	0
prednisolone	low	3	0
thyroxine	low	3	0
prednisone	low	3	0
triiodothyronine	low	2	0
chloramphenicol	low	5	0
glutamine	low	1	0
adenosine diphosphate	low	1	0
bromodeoxyuridine	low	1	0
carbostyril	low	1	0
edetic acid	low	1	0
tyrosine	low	3	0
colchicine	low	1	0
cycloheximide	low	1	0
mannitol	low	1	0
arginine	low	1	0
methylprednisolone	low	1	0
n-vinyl-2-pyrrolidinone	low	1	0
meglumine	medium	1	1
isoxazoles	medium	2	2
nitroblue tetrazolium	low	1	0
c.i. 42510	low	1	0
erythromycin	low	1	0
dehydroepiandrosterone sulfate	low	1	0
vancomycin	low	2	0
fucose	low	1	0
fluorescein-5-isothiocyanate	low	1	0
imidocarb	low	9	0
4-chloro-7-nitrobenzofurazan	low	1	0
trolamine salicylate	low	3	0
tetradecanoylphorbol acetate	low	2	0
clonixin	low	1	0
transferrin	low	1	0
glutamic acid	low	1	0
amoxicillin	low	2	0
paclitaxel	low	1	0
amitraz	medium	2	1
flunixin meglumine	low	1	0
ng-nitroarginine methyl ester	low	1	0
permethrin	medium	7	3
closantel	low	2	0
fenoxaprop ethyl	low	2	0
meglumine antimoniate	medium	1	1
cephalosporin c	low	2	0
enrofloxacin	low	1	0
fibrinogen	low	1	0
glycidyl nitrate	low	3	0
foxes	low	20	0
omega-n-methylarginine	low	1	0
ezetimibe	low	1	0
symmetric dimethylarginine	low	1	0
biotin	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	4	0
n-acetylneuraminic acid	low	2	0
betadex	low	1	0
tretinoin	low	2	0
tacrolimus	low	2	0
mycophenolic acid	low	1	0
zithromax	medium	1	1
aphidicolin	low	1	0
fumonisin b1	low	1	0
sodium dodecyl sulfate	low	1	0
bilirubin	low	1	0
dinoprostone	low	2	0
sirolimus	low	1	0
deamino arginine vasopressin	low	1	0
methoprene	medium	3	2
flumethrin	medium	3	1
mocetinostat	low	2	0
lipid a	low	1	0
u 18666a	low	1	0
imidocarb dipropionate	low	6	0
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc	low	1	0
rifamycins	low	1	0
acid phosphatase	low	1	0
oligonucleotides	low	1	0
phosphatidylcholines	low	1	0
ro13-9904	low	3	0
afoxolaner	medium	1	1
interleukin-8	low	3	0
tetracycline	low	19	0
oxytetracycline, anhydrous	medium	14	2
minocycline	medium	3	1
piroxicam	medium	1	1
sybr green i	low	2	0
pyrethrins	medium	4	1
lewis x antigen	low	1	0
cyclosporine	low	1	0
cytochalasin d	low	1	0
thromboplastin	low	1	0
muramidase	low	1	0
exudates	low	4	0
cyclic gmp	low	2	0
guanosine triphosphate	low	1	0
folic acid	low	1	0
3-methyladenine	low	1	0
rifampin	low	11	0
allopurinol	medium	1	1
sildenafil citrate	low	1	0
bis(3',5')-cyclic diguanylic acid	low	2	0
imidacloprid	medium	7	4
eye	low	2	0
concanavalin a	low	2	0

Protein Targets (1,351)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	15	0	0	15
USP1 protein, partial	22	0	0	22
TDP1 protein	41	0	0	41
vitamin D3 receptor isoform VDRA	14	0	0	14
importin subunit beta-1 isoform 1	4	0	0	4
flap endonuclease 1	9	0	0	9
serine/threonine-protein kinase PLK1	6	0	0	6
snurportin-1	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	13	0	0	13
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	32	0	0	32
DNA polymerase kappa isoform 1	17	0	0	17
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	1	1	4
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	1	1	2
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	1	2
Mitogen-activated protein kinase 14	0	2	1	3
Chain A, DNA-3-methyladenine glycosylase I	0	0	1	1
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I	0	0	1	1
Chain A, Dna-3-methyladenine Glycosylase I	0	0	1	1
EWS/FLI fusion protein	16	0	0	16
NPYLR7B	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	20	0	0	20
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	24	0	0	24
AR protein	40	0	0	40
nuclear receptor subfamily 1, group I, member 3	21	0	0	21
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
glucocorticoid receptor [Homo sapiens]	30	0	0	30
estrogen-related nuclear receptor alpha	36	0	0	36
pregnane X nuclear receptor	29	0	0	29
estrogen nuclear receptor alpha	50	0	0	50
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
heat shock protein beta-1	8	0	0	8
tumor susceptibility gene 101 protein	1	0	0	1
lamin isoform A-delta10	26	0	0	26
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Bile salt export pump	0	32	0	32
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	2	1	4
Glutamate receptor 2	15	3	1	19
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	11	0	0	11
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	12	0	0	12
Ataxin-2	13	0	0	13
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	9	0	0	9
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	2	3
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	0	1	1
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	2	0	0	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
interleukin 8	10	0	0	10
thyroid stimulating hormone receptor	12	0	0	12
estrogen receptor 2 (ER beta)	16	0	0	16
progesterone receptor	20	0	0	20
IDH1	11	0	0	11
euchromatic histone-lysine N-methyltransferase 2	28	0	0	28
Bloom syndrome protein isoform 1	7	0	0	7
transcriptional regulator ERG isoform 3	3	0	0	3
thyroid hormone receptor beta isoform 2	31	0	0	31
ras-related protein Rab-9A	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	30	0	0	30
survival motor neuron protein isoform d	8	0	0	8
ATP-binding cassette sub-family C member 3	0	23	0	23
Multidrug resistance-associated protein 4	0	24	0	28
Polyphenol oxidase 2	0	1	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	28	0	0	28
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	22	0	22
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
GLI family zinc finger 3	24	0	0	24
retinoic acid nuclear receptor alpha variant 1	27	0	0	27
retinoid X nuclear receptor alpha	28	0	0	28
farnesoid X nuclear receptor	17	0	0	17
cytochrome P450 2D6	11	0	0	11
peroxisome proliferator activated receptor gamma	21	0	0	21
vitamin D (1,25- dihydroxyvitamin D3) receptor	19	0	0	19
aryl hydrocarbon receptor	19	0	0	19
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
thyroid hormone receptor beta isoform a	14	0	0	14
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
cytochrome P450 3A4 isoform 1	11	0	0	11
Gamma-aminobutyric acid receptor subunit pi	11	1	1	13
Alpha-2A adrenergic receptor	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	11	1	1	13
Gamma-aminobutyric acid receptor subunit delta	11	1	1	13
Gamma-aminobutyric acid receptor subunit gamma-2	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-5	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-3	11	1	1	13
Gamma-aminobutyric acid receptor subunit gamma-1	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-2	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-4	11	1	1	13
Gamma-aminobutyric acid receptor subunit gamma-3	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-6	11	1	1	13
Gamma-aminobutyric acid receptor subunit alpha-1	11	2	1	14
Gamma-aminobutyric acid receptor subunit beta-3	11	1	1	13
Gamma-aminobutyric acid receptor subunit beta-2	11	1	1	13
Peroxisome proliferator-activated receptor alpha	2	0	0	2
GABA theta subunit	11	1	1	13
Gamma-aminobutyric acid receptor subunit epsilon	11	1	1	13
Chain A, Beta-lactamase	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	8	0	0	8
Beta-lactamase	0	0	0	1
Bile salt export pump	0	4	0	4
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Cytochrome P450 2C9	0	10	1	11
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	1	0	2
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Cytochrome P450 2J2	0	7	0	7
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
ATAD5 protein, partial	6	0	0	6
67.9K protein	10	0	0	10
peroxisome proliferator-activated receptor delta	19	0	0	19
chromobox protein homolog 1	16	0	0	16
Nicotinate phosphoribosyltransferase	0	3	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
huntingtin isoform 2	2	0	0	2
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase beta	0	1	0	1
DNA polymerase beta	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	1	2
DNA polymerase delta catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase subunit gamma-1	0	1	0	1
DNA polymerase lambda	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	12	0	0	12
NFKB1 protein, partial	2	0	0	2
GLS protein	10	0	0	10
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
muscarinic acetylcholine receptor M1	6	0	0	6
lethal factor (plasmid)	9	0	0	9
Cytochrome P450 3A4	0	11	2	14
Nitric oxide synthase, endothelial	0	2	0	4
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, inducible	0	3	1	6
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	7	0	0	7
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
aldehyde dehydrogenase 1 family, member A1	19	0	0	19
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	8	0	0	8
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
Prostaglandin-H2 D-isomerase	0	2	0	2
Solute carrier family 22 member 6	0	3	0	3
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	4	1	5
Carbonic anhydrase 1	0	6	0	11
Carbonic anhydrase 2	0	6	0	12
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	1	2	1	4
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	1	1	1	3
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	2	0	4
Adenosine receptor A2a	0	2	0	4
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	7	1	8
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	9	1	1	11
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, D-MALTODEXTRIN BINDING PROTEIN	0	0	1	1
Chain A, Limit Dextrinase	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain A, Solute-binding protein	0	0	1	1
Chain B, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, SusD	0	0	1	1
Chain A, Alpha-hemolysin	0	0	1	1
Chain B, Alpha-hemolysin	0	0	1	1
Chain C, Alpha-hemolysin	0	0	1	1
Chain D, Alpha-hemolysin	0	0	1	1
Chain E, Alpha-hemolysin	0	0	1	1
Chain F, Alpha-hemolysin	0	0	1	1
Chain G, Alpha-hemolysin	0	0	1	1
activating transcription factor 6	13	0	0	13
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Chain A, Cruzipain	7	0	0	7
Microtubule-associated protein tau	9	0	0	9
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	8	0	12
Solute carrier organic anion transporter family member 1B1	0	12	0	17
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Stimulator of interferon genes protein	0	0	1	1
Stimulator of interferon genes protein	0	0	2	2
RocR	0	1	0	1
pregnane X receptor	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
arylsulfatase A	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
cellular tumor antigen p53 isoform a	4	0	0	4
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
oxysterols receptor LXR-beta isoform 1	0	0	1	1
peripheral myelin protein 22	14	0	0	14
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Spike glycoprotein	9	0	1	10
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Carbonic anhydrase 12	0	2	0	5
Carbonic anhydrase 3	0	2	0	5
Carbonic anhydrase 4	0	4	0	7
Carbonic anhydrase 6	0	2	0	5
Carbonic anhydrase 5A, mitochondrial	0	2	0	5
Carbonic anhydrase 7	0	2	0	5
Carbonic anhydrase 9	0	2	0	5
Carbonic anhydrase 15	0	3	0	5
Carbonic anhydrase 13	0	1	0	3
Carbonic anhydrase 14	0	2	0	5
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
Chain A, serum paraoxonase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	15	0	0	15
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
G	15	0	0	15
streptokinase A precursor	0	0	5	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
Interferon beta	19	0	0	19
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
50S ribosomal protein L36 2	0	4	1	5
Inositol hexakisphosphate kinase 1	15	0	0	15
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	15	0	0	15
Carbonic anhydrase	0	2	0	4
cytochrome P450 2C9 precursor	4	0	0	4
Cytochrome P450 1A2	0	1	1	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	3
DNA gyrase subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
Cytochrome P450 2D6	0	2	1	3
DNA topoisomerase 2-alpha	0	1	1	5
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	3	1	4
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	6	0	1	7
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Potassium voltage-gated channel subfamily H member 2	0	6	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Luciferase	11	0	0	11
UDP-glucuronosyltransferase 2B7	0	1	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
glucose-6-phosphate dehydrogenase	0	1	0	1
glp-1 receptor, partial	9	0	0	9
SUMO-1	0	1	0	1
TSHR protein	1	0	0	1
Smad3	6	0	0	6
PINK1	1	0	0	1
Parkin	4	0	0	4
hexokinase	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
histone acetyltransferase KAT2A isoform 1	7	0	0	7
bcl-2-like protein 11 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	3	0	5
Long-chain-fatty-acid--AMP ligase FadD32	0	1	0	1
Rap guanine nucleotide exchange factor 3	6	0	0	6
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	2	1	3
Sporulation initiation phosphotransferase F	0	1	0	1
Neutrophil elastase	0	3	0	3
60 kDa chaperonin	0	4	0	4
Adenosine receptor A3	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	6	0	6
Alpha-1B adrenergic receptor	0	6	0	6
Sporulation kinase A	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Acetylcholinesterase	0	2	0	2
Thromboxane-A synthase	0	2	0	2
Mitogen-activated protein kinase 1	0	2	1	3
Alpha-1A adrenergic receptor	0	6	0	6
10 kDa heat shock protein, mitochondrial	0	6	0	6
Sodium-dependent dopamine transporter	0	2	0	2
Thiosulfate sulfurtransferase	0	6	0	6
Chitinase	0	2	0	2
60 kDa chaperonin	0	6	0	6
10 kDa chaperonin	0	6	0	6
Rap guanine nucleotide exchange factor 4	1	0	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Chain A, Ferritin light chain	4	0	0	4
endonuclease IV	1	0	0	1
PAX8	0	0	0	1
Fumarate hydratase	4	0	0	4
PPM1D protein	5	0	0	5
Thrombopoietin	1	0	0	1
polyprotein	4	0	0	4
cytochrome P450 2D6 isoform 1	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	5	0	0	5
neuropeptide S receptor isoform A	4	0	0	4
Solute carrier family 22 member 3	0	2	0	3
Tubulin alpha-1A chain	0	2	2	5
Tubulin beta chain	0	2	2	4
Plasma kallikrein	0	0	0	3
Tubulin beta-4A chain	0	3	3	8
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin beta chain	0	3	3	8
ATP-dependent translocase ABCB1	0	8	1	19
Tubulin alpha-3C chain	0	3	3	8
Serine/threonine-protein kinase pim-1	0	1	1	2
ATP-dependent translocase ABCB1	0	5	0	6
Tubulin alpha-1B chain	0	3	3	8
Tubulin alpha-4A chain	0	3	3	8
Tubulin beta-4B chain	0	3	3	8
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	4	3	9
Tubulin beta-2A chain	0	3	3	8
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	3	8
Tubulin beta-2B chain	0	2	1	5
Tubulin alpha-3E chain	0	3	3	8
Tubulin alpha-1A chain	0	3	3	8
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	3	3	8
Tubulin beta-6 chain	0	3	3	8
Tubulin beta-2B chain	0	3	3	8
Tubulin beta-1 chain	0	3	3	8
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
P53	1	0	0	1
RPL19A	0	0	1	1
Histone H2A.x	8	0	0	8
Spike glycoprotein	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	2	0	2
Hexose transporter 1	0	2	0	2
Procathepsin L	0	1	1	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Alpha-synuclein	5	3	0	8
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	6	2	8
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	3	1	4
Hypoxia-inducible factor 1-alpha	0	1	1	2
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Lysine-specific demethylase 4A	0	1	0	1
Methylcytosine dioxygenase TET2	0	1	0	1
Deoxyhypusine hydroxylase	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	5
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Steryl-sulfatase	0	0	0	1
Multidrug resistance-associated protein 1	0	3	1	6
Solute carrier organic anion transporter family member 1A1	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	2	0	5
G-protein coupled bile acid receptor 1	0	0	1	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	1	0	4
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	2
SMAD family member 2	7	0	0	7
SMAD family member 3	7	0	0	7
thyroid stimulating hormone receptor	10	0	0	10
prostaglandin E2 receptor EP2 subtype	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
Solute carrier family 22 member 2	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	3	0	4
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	2	0	4
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Amyloid-beta precursor protein	0	3	0	3
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
nonstructural protein 1	4	0	0	4
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Albumin	0	1	6	7
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	2	0	2
Reverse transcriptase/RNaseH	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	4
Sodium/bile acid cotransporter	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
glycogen synthase kinase-3 alpha	0	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
DNA polymerase beta	2	0	0	2
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	2	2
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	4	1	7
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	7
Glutamate receptor ionotropic, NMDA 2B	0	4	1	7
Glutamate receptor ionotropic, NMDA 2C	0	4	1	7
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	4	1	7
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	4	1	7
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	1	7
Chain A, Glutamine Binding Protein	0	0	1	1
15-lipoxygenase, partial	4	0	0	4
peripheral myelin protein 22 isoform 1	2	0	0	2
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	1	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	3	2	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	3	4
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	2	2	4
Carbonic anhydrase	0	0	0	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	3
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	0	0	3
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Histamine H3 receptor	0	1	2	3
Cdk-related protein kinase 6	0	1	0	1
Protein kinase domain-containing protein	0	1	0	1
Calcium-dependent protein kinase 1	0	1	0	1
Mitogen-activated protein kinase	0	1	0	1
Proline--tRNA ligase	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
Lysine--tRNA ligase	0	1	0	1
acetylcholinesterase	4	0	0	4
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
M-phase phosphoprotein 8	2	0	0	2
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Interleukin-8	0	1	0	1
Androgen receptor	0	3	1	4
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	1	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Sodium/myo-inositol cotransporter 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Cholinesterase	0	1	0	1
thioredoxin glutathione reductase	4	0	0	4
caspase 7, apoptosis-related cysteine protease	2	0	0	2
caspase-3	2	0	0	2
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein-arginine deiminase type-4	0	4	0	4
Histone deacetylase 3	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	2	0	2
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	3
Collagenase 3	0	3	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	2
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
phosphoglycerate kinase	1	0	0	1
Genome polyprotein	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Integrin alpha-V	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Fibroblast growth factor receptor 1	0	1	1	2
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
UDP-glucuronosyltransferase 1-6	0	1	0	1
Substance-K receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	1	2
Beta-tubulin	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
serine-protein kinase ATM isoform a	1	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	2	1	3
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C zeta type	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	3	0	3
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Beta-1 adrenergic receptor	0	1	0	1
Protein kinase C eta type	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Serine/threonine-protein kinase D1	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	2	4	6
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
5-hydroxytryptamine receptor 1A	0	3	0	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Cytochrome P450 2C8	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(9)

Research Excerpts

Overview

Context

Treatment

Research

Studies (229)

Protein Targets (1,351)

E chaffeensis Infection

Synonyms(9)

Research Excerpts

Overview

Context

Treatment

Research

Studies (229)

Drugs Studied (152)

Protein Targets (1,351)