The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.
| Excerpt | Reference |
|---|
| "The way the scar is formed and the factors affecting the final appearance are discussed." | ( Gunter, JP, 1978) |
| "The linear scar is created as part of a circle, so that the postoperative contracture will improve the alar contour." | ( Brody, GS; Grace, SG, 1978) |
| "Hypertrophic scar is an unacceptably enlarged scar, within the boundaries of the original wound; whereas keloid is an unacceptably enlarged scar infiltrating the surrounding tissue." | ( Hahn, T; Pilegaard, J; Wester, JU, 1989) |
| "Significant scarring is a potential sequela of the second degree burns produced by argon or carbon dioxide laser surgery, and is particularly a risk for children." | ( Brauner, GJ; Schliftman, A, 1987) |
| "Facial burn scars are difficult to conceal and often preclude an aesthetic rehabilitation of the patient." | ( Argenta, LC; Friedman, RJ; Marks, MW; Thornton, JW, 1988) |
| "A wide spread scar is best treated with excision and closure." | ( Rudolph, R, 1987) |
| "Postoperative scar is one of the causes of extraosseous localization of Tc-99m phosphonate bone agents." | ( DeLand, FH; Dillon, ML; Domstad, PA; Shih, WJ, 1984) |
| "Hypertrophic scars are prevented." | ( Leviet, D; Mitz, V; Vilain, R, 1982) |
| "Scarring is a major cause of many clinical problems." | ( Ferguson, MW; Foreman, DM; Shah, M, 1994) |
| "Scarring is a well-known side effect to cutaneous laser treatment." | ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993) |
| "Scarring is a well-known side-effect of cutaneous laser treatment and exposure to solar ultraviolet radiation is suspected to increase scar formation." | ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993) |
| "Hypertrophic scarring is characterized by disordered collagen fibrils." | ( Garg, A; Garg, HG; Neame, PJ; Siebert, JW, 1996) |
| "Atrophic acne scars are a frequent problem after acne." | ( Donath, P; Hannes, J; Neumayer, R; Perl, S; Reiner, A; Schmidt, JB, 1999) |
| "The risk of renal scarring is greatest after severe acute pyelonephritis involving greater than 66% of a renal zone." | ( Chandra, R; Majd, M; Park, JS; Pohl, HG; Rushton, HG, 1999) |
| "Since risk of renal scarring is believed to occur more frequently in young people, and since recurrent urinary infections mainly affect girls, the age and sex of subjects are important in the design of a prophylactic regimen." | ( Bollgren, I, 1999) |
| "Infarct scar is composed of phenotypically transformed fibroblast-like cells, termed myofibroblasts (myoFb) because they express alpha-smooth muscle actin (alpha-SMA) and these microfilaments confer contractile behavior in response to various peptides and amines." | ( Sun, Y; Weber, KT, 2000) |
| "Treatment of acne scarring is a challenging problem for dermatologists and cosmetic surgeons." | ( Weinstein, C, 1999) |
| "Scarring is markedly reduced in MRL mice compared with C57BL/6 mice, consistent with both the reduced hydroxyproline levels seen after injury and an elevated cardiomyocyte mitotic index of 10-20% for the MRL compared with 1-3% for the C57BL/6." | ( Bedelbaeva, K; Heber-Katz, E; Lankford, EB; Leferovich, JM; Samulewicz, S; Zhang, XM; Zwas, D, 2001) |
| "Scars are commonly encountered by dermatopathologists and usually do not present a diagnostic challenge." | ( Bergfeld, WF; House, NS; Kamath, NV; Ormsby, A, 2002) |
| "Management of these scars is prolonged, and the patient must understand that the ultimate result will usually be a compromise." | ( Horswell, BB, 1998) |
| "Acne scarring is a common complication of acne and yet no appropriate and effective single treatment modality has been developed." | ( Chung, WG; Kwahck, H; Lee, JB; Lee, KH, 2002) |
| "Renal scarring is an important cause of chronic renal failure and hypertension in children." | ( Cieślak-Puchalska, A, 2001) |
| "Vocal fold scarring is characterized by altered biomechanical properties, which create dysphonia." | ( Bless, DM; Gray, SD; Thibeault, SL, 2003) |
| "Atrophic scars are a frequent consequence of acne, with a negative esthetic and psychological influence." | ( Knor, T, 2004) |
| "The scar is the effect of synthesis and degradation of extracellular matrix." | ( Czarkowska-Paczek, B; Przybylski, J, 2004) |
| "Vocal fold scarring is the greatest cause of poor voice after vocal fold injury." | ( Hansen, JK; Thibeault, SL, 2006) |
| "Visible scars are reduced and recovery time is diminished." | ( Chang, CJ, 2005) |
| "Scarring is one of the steps of excessive wound healing, causing dysfunction of the involved tissues and clinically poor cosmetics." | ( Akyol, H; Bingul, SM; Colak, E; Kaptanoglu, L; Kucuk, HF; Kurt, N; Torlak, OA, 2006) |
| "Acne scarring is a common manifestation that remains a therapeutic challenge to dermatologists, dermatologic surgeons, and plastic surgeons." | ( Howard, MS; Kent, DE; Lane, JE; Yug, A, 2006) |
| "Vocal fold scarring is the major cause of voice disorders after voice surgery or laryngeal trauma." | ( Bless, DM; Lim, X; Muñoz-Del-Río, A; Tateya, I; Tateya, T, 2006) |
| "As is well known, scars are the indelible ransom of any surgical procedure and the major obstacle confronting patients and surgeons from an aesthetic standpoint." | ( Frechet, P, 2007) |
| "Renal scarring is known to be associated with hypertension." | ( Ahmed, M; Eggleston, D; Jain, A; Kapur, G; Mattoo, TK; Valentini, RP, 2008) |
| "The presence of scarring is difficult to diagnose both clinically and histologically." | ( Goldberg, LJ, 2009) |
| "Permanent renal scars are diagnosed by dimercapto-succinic acid (DMSA) scan several months later." | ( Donovan, R; Narchi, H, 2008) |
| "Keloids and other scars are different manifestations of the normal wound healing process." | ( Amini, S; Berman, B; Konda, S; Viera, MH, 2009) |
| "Acne scarring is a common complication of acne but no effective single treatment modality has been developed." | ( Kim, HJ; Kim, TG; Kwon, YS; Lee, JH; Park, JM, 2009) |
| "Atrophic scars are a common complication of acne." | ( Kang, WH; Kim, JH; Kim, YJ; Park, SJ; Pyo, WS, 2009) |
| "Their scars are generally treated by tissue transfer, W- and Z-plasties, flaps, cortisone injections or ablative procedures that injure or destroy the epidermis and its basement membrane and subsequently lead to fibrosis of the papillary dermis." | ( Altintas, MA; Aust, MC; Gohritz, A; Ipaktchi, R; Knobloch, K; Redeker, J; Reimers, K; Schwaiger, N; Vogt, PM, 2010) |
| "A scar is usually developed by an imbalance of collagen synthesis and degradation." | ( Cho, JW; Cho, SY; Lee, KS; Lee, SR, 2010) |
| "Renal scarring is a serious complication that often occurs with chronic pyelonephritis in the presence of vesicoureteral reflux." | ( Hoshinaga, K; Ichino, M; Kurahashi, H; Kuroyanagi, Y; Kusaka, M; Mori, T; Morooka, M; Sasaki, H; Shiroki, R; Shishido, S, 2010) |
| "Acne scarring is common but difficult to treat." | ( Jansen, T; Podda, M, 2010) |
| "Myocardial infarct scars are usually imaged by delayed-enhanced cardiac magnetic resonance (DE-cMR)." | ( Chenot, F; Gerber, BL; Goffinet, C; Montant, P; Pasquet, A; Poncelet, A; Vancraeynest, D; Vanoverschelde, JL, 2010) |
| "Facial scars are easily recognized in the community and become a source of lifelong guilt, shame, and regret for the patients." | ( Kulahci, Y; Oksuz, S; Sahin, C; Sever, C; Uygur, F; Yuksel, F, 2010) |
| "Acne scars are difficult to treat." | ( Bhardwaj, D; Khunger, M; Khunger, N, 2011) |
| "Acne scarring is common but surprisingly difficult to treat." | ( Bassiouny, DA; El-Komy, MH; El-Tobshy, SA; Ramadan, SA, 2011) |
| "Scars are usually classified into atrophic scars, hypertrophic scars, or keloids." | ( Choudhary, S; Elsaie, ML; McLeod, M; Nouri, K, 2011) |
| "Excessive dermal scarring is characterized by an overabundant deposition of extracellular matrix caused by fibrosis." | ( Bian, F; Boys, M; Chan, K; Chio, C; Lala, DS; Pocalyko, D; Ren, XD; Render, J, 2011) |
| "A keloid scar is a benign proliferative lesion of dermic collagen." | ( Beogo, R; Guiébré, YM; Ouoba, K; Sérémé, M; Zwetyenga, N, 2012) |
| "Hypopigmented scarring is a challenging condition to treat, with current treatments showing limited efficacy and temporary results." | ( Fabi, SG; Fitzpatrick, R; Massaki, AB, 2012) |
| "The keloid scar is a thick skin or the cornea of man, due to excessive accumulation of type I collagen in the dermis." | ( Allah, KC; Assi Djè Bi Djè, V; Kossoko, H; Richard Kadio, M; Yéo, S, 2013) |
| "The widening of the scar is a common problem in children but can be reduced by suture in two layers associated with local reconstruction." | ( Calibre, C; Duquennoy-Martinot, V; Herbaux, B; Maillet-Declerck, M, 2012) |
| "Scar is useful in rapidly sealing an injured area, but can also lead to significant morbidity." | ( Gallo, PH; Kathju, S; Satish, L, 2012) |
| "Skin scars are a normal outcome of the tissue repair process." | ( Kircik, LH, 2013) |
| "Greater preablation scar is associated with LA dilatation and AF recurrence." | ( Ariff, B; Bai, W; Boubertakh, R; Davies, DW; Francis, DP; Hunter, R; Jamil-Copley, S; Jones, D; Juli, C; Kanagaratnam, P; Karim, R; Kojodjojo, P; Lim, PB; Malcolme-Lawes, LC; Peters, NS; Petersen, SE; Quest, R; Rueckert, D; Schilling, R, 2013) |
| "Incision scars are deeper than burned scars, and their success rates are poor." | ( Hoon Koh, S; Jung, S; Oh, SJ, 2013) |
| "Acne scars are a common concern in dermatology." | ( Schweiger, ES; Sundick, L, 2013) |
| "Surgical scarring is a common cosmetic problem that occurs in various surgical fields, including dermatology." | ( Kang, KH; Oh, IY; Park, KY; Park, SJ; Seo, SJ, 2013) |
| "Scarring is a very common complication of severe acne and is difficult to treat by conventional methods." | ( Hamblin, MR; Hao, F; Lin, L; Xiao, Y; Yin, R, 2014) |
| "Scar is associated with impaired regional LV wall motion and is expected to result in a reduction in the corresponding amplitude values derived from phase analysis." | ( Beanlands, RS; Birnie, D; deKemp, RA; Lalonde, M; Ruddy, TD; Wassenaar, R; Wells, RG, 2014) |
| "Keloid scarring is more prevalent in individuals of African, Asian, and Hispanic descent." | ( Kundu, RV; Madu, P, 2014) |
| "Surgical scar care should be continued for one year." | ( Harijan, A; Son, D, 2014) |
| "Whether the scar is beneficial or detrimental to recovery remains controversial." | ( Coulter, M; Levine, JM; Meyer, RL; Miotke, J; Rodriguez, JP; Takemaru, K, 2014) |
| "Because acne scarring is associated with substantially reduced quality of life, early initiation of effective treatment is desirable." | ( Chang, SE; Kim, HW; Kim, JE; Ko, JY; Ro, YS, 2014) |
| "Scarring is a significant medical burden; financially to the health care system and physically and psychologically for patients." | ( Dong, Y; Fan, C; Leavesley, DI; Li, K; Lynam, E; Su, Y; Upton, Z; Xie, Y; Yang, Y, 2015) |
| "Acne scarring is a common sequela of acne for which no single treatment method is uniformly effective." | ( Agarwal, N; Gupta, LK; Khare, AK; Kuldeep, CM; Mittal, A, 2015) |
| "Hill and valley scarring is 1 of 3 atrophic scar types that occur as a result of acne, becoming more apparent with facial skin aging." | ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015) |
| "Lesion-induced scarring is a major impediment for regeneration of injured axons in the central nervous system (CNS)." | ( Brazda, N; Estrada, V; Faissner, A; König, B; Krafft, S; Müller, HW; Vogelaar, CF; Ziegler, B, 2015) |
| "Atrophic acne scars are a common and psychologically devastating sequela of acne vulgaris that are refractory to the vast majority of topical treatments." | ( Moy, RL; Seidel, R, 2015) |
| "Scarring is an expected result of trauma to the skin." | ( Damsgaard, TE; Hammer-Hansen, N; Rødgaard, JC, 2015) |
| "Scars are problematic for thousands of patients." | ( Martínez-Carpio, PA; Trelles, MA, 2016) |
| "Hypertrophic scarring is a common dermal fibroproliferative disorder characterized by excessive collagen deposition." | ( Chen, L; Liu, X; Qi, S; Shu, B; Tang, J; Xie, J; Xu, Y; Zhang, L; Zhao, J, 2016) |
| "Surgical scars are best treated with a combination approach to address various features of the scar." | ( Cohen, JL; Eilers, RE; Ortiz, AE; Ross, EV, 2016) |
| "These scars are characterized by dysregulated growth with excessive collagen formation, and can be cosmetically and functionally disruptive to patients." | ( Berman, B; Maderal, A; Raphael, B, 2017) |
| "Background Central scars are rarely reported in conventional hepatocellular carcinoma (HCC)." | ( Ha, SY; Han, SB; Jeong, WK; Kim, YK; Lee, WJ; Min, JH, 2018) |
| "Postoperative scarring is one the factors associated with surgery failure." | ( Pimentel, E; Schmidt, J, 2018) |
| "Scarring is the response elicited by the skin surface to injury and loss of tissue material." | ( Amici, JM; Chaussade, V, 2016) |
| "Acne scars are a major concerning problem to all acne patients affecting their quality of life." | ( Al Refae, AA; Al Taweel, AI; Hamed, AM; Kamal, AM, 2019) |
| "Hypertrophic scarring is a common condition in the Chinese population; however, there are currently no satisfactory drugs to treat the disorder." | ( Guo, S; Lei, L; Ma, X; Song, B; Song, Y; Su, Y; Yu, Z, 2018) |
| " Detecting renal scar is important in pediatric patients with vesicoureteral reflux (VUR) for deciding on treatment option." | ( Bayram, G; Karabulut, B; Ozcift, B; Oztorun, CI; Tiryaki, TH, 2019) |
| "Myocardial scars are equally best visualized with delay time of 5 and 7 min post contrast administration." | ( Goto, Y; Hamdy, A; Kitagawa, K; Nagasawa, N; Nakamura, S; Sakuma, H; Takafuji, M; Yamada, A, 2019) |
| "Atrophic acne scarring is a frequent occurrence among acne patients." | ( Baldwin, H; Lain, E; Stein Gold, L; Tan, J; Tanghetti, E, 2019) |
| "Pathological scarring is a result of the hypertrophy of scar tissue during tissue repair following trauma." | ( Cao, Z; Jiang, Q; Lai, Z; Long, S; Na, S; Pan, S; Xin, Y; Yan, J; Zhang, J, 2019) |
| "Scarring is a frequent consequence of acne." | ( Barankin, B; Bissonnette, R; Chavda, R; Dréno, B; Gagné-Henley, A; Kerrouche, N; Lynde, C; Tan, J, 2019) |
| "Pathological scarring is an intractable problem for both patients and clinicians." | ( Fan, C; Leavesley, D; Lim, LKP; Loh, SQ; Upton, Z; Ying Lim, KY, 2019) |
| "Acne scars are the most common sequelae of the severe inflammatory process of acne, and its managing is a challenge." | ( Antonino, A; Francesco, A, 2021) |
| "Acne scars are common problems encountered in daily dermatologic practice." | ( Abtan, AF; Al-Dhalimi, MA; Al-Hamamy, HR, 2021) |
| "Renal scarring is a serious complication in recurrent urinary tract infections (UTIs)." | ( Erdoğan, S; Sürmeli Döven, S, 2021) |
| "Scars are generated in mature skin as a result of the normal repair process, but the replacement of normal tissue with scar tissue can lead to biomechanical and functional deficiencies in the skin as well as psychological and social issues for patients that negatively affect quality of life." | ( Bayat, A; Ud-Din, S; Wilgus, TA, 2020) |
| "Acne scarring is a common disfiguring complication of acne, and fractional lasers are widely applied in improving it." | ( Cai, S; Lu, K, 2022) |
| "Scarring is a common complication of acne vulgaris with a significant impact on the psychological well-being of patients." | ( Lim, D; Sun, C, 2022) |
| "Hypertrophic scars are an unwanted and mutilating consequence of deep burns, and are further exacerbated by extensive burn injuries." | ( Klosová, H; Langová, K; Xinopulos, P; Zálešák, B, 2021) |
| "The scarring is driven by inflammatory processes, particularly the TGF-β signaling pathways, resulting in excess synthesis and deposition of the extracellular matrix, especially collagen." | ( Abdollahimajd, F; Hajimoradi, B; Mansouri, P; Pourani, MR; Rakhshan, A; Uitto, J; Vahidnezhad, H; Youssefian, L, 2022) |
| "Scars are common and intractable consequences after scalded wound healing, while monotherapy of epidermal growth factors does not solve this problem." | ( Chen, HB; Cheng, F; Pang, YX; Su, DD; Tian, XH; Wei, L; Xi, LF; Yang, C; Yang, XR; Zhang, MQ; Zhang, WX; Zhu, XF, 2022) |
| "A burn scar is a type of hypertrophic scar that can cause significant clinical symptoms, discomfort, and post-burn scar (PBS) syndrome in up to 77% of patients with burn injuries." | ( Chen, CC; Chen, SP; Hsu, CH; Lyu, SY, 2021) |
| "Self-harm scars are a consequence of deliberate self-injury, serving as a visual reminder for involved individuals." | ( Akers, KG; Edriss, M; Mehregan, D; Monconduit, R; St Claire, K, 2022) |
| "Scarring is one of the most esthetically challenging and psychologically burdening aspects following inflammatory acne." | ( Ahmadzade, M; Ahramiyanpour, N; Akbari, Z; Jamali, M; Sarvipour, N; Shafie'ei, M, 2022) |
| "Myocardial scars are assessed noninvasively using cardiovascular magnetic resonance late gadolinium enhancement (LGE) as an imaging gold standard." | ( Burrage, MK; Channon, KM; Dharmakumar, R; Ferreira, VM; Gonzales, RA; Leal Pelado, J; Lee, YP; Lukaschuk, E; Mills, R; Myerson, SG; Neubauer, S; Nikolaidou, C; Piechnik, SK; Popescu, IA; Rider, O; Shanmuganathan, M; Thomas, KE; Zhang, Q; Zhang, X, 2022) |
| "Atrophic acne scars are the most common cutaneous seqaule of acne vulgaris, representing 80%-90% of all acne scars." | ( Alahmadi, RA; Alamri, AM; Aljefri, YE; Alkhamisi, TA; Alkhunani, TA; Ghaddaf, AA; Samarkandy, SJ, 2022) |
| "Inflammation-driven scarring is a major contributor to surgical failure after subconjunctival bleb forming glaucoma surgery." | ( Armstrong, JJ; Hutnik, CML; Liu, H; Vinokurtseva, A, 2022) |
| "Scarring is a common and undesirable outcome of acne vulgaris." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "Scarring is a common and undesirable outcome of acne vulgaris." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "Scarring is a common and undesirable outcome of acne vulgaris." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "Peptic or ESD ulcer scarring is a risk factor for AL after esophagectomy in addition to diabetes mellitus." | ( Bamba, T; Hanyu, T; Hirose, Y; Ichikawa, H; Ishikawa, T; Kano, Y; Kosugi, SI; Miura, K; Motegi, D; Muneoka, Y; Nakagawa, S; Sakata, J; Shimada, Y; Tajima, Y; Usui, K; Wakai, T, 2023) |
| "Peptic or ESD ulcer scarring is a risk factor for AL after esophagectomy in addition to diabetes mellitus." | ( Bamba, T; Hanyu, T; Hirose, Y; Ichikawa, H; Ishikawa, T; Kano, Y; Kosugi, SI; Miura, K; Motegi, D; Muneoka, Y; Nakagawa, S; Sakata, J; Shimada, Y; Tajima, Y; Usui, K; Wakai, T, 2023) |
| "Scarring is a common but difficult to manage consequence of acne vulgaris." | ( Bikash, C; Sarkar, R, 2023) |
| "Acne scars are a permanent disfiguring sequel of acne." | ( Choudhary, P; Relhan, V; Sahoo, B; Sarkar, R; Solanki, B, 2023) |
| "Renal scarring is a serious complications of urinary tract infection and vesicoureteral reflux (VUR)." | ( Eskandarifar, A; Naghshizadian, R; Tari, A, 2023) |
| "Acne scars are common in patients with moderate to severe acne." | ( Dong, Y; He, S; Hu, D; Hu, G; Huang, S; Li, Y; Liu, J; Shen, H; Wang, Z; Xue, H; Ye, D; Zeng, WH; Zhu, Y, 2023) |
| "Corneal scarring is usually more severe in the central cornea based on clinical observation." | ( Dong, M; Dong, Q; Li, S; Qu, M; Shi, W; Wang, N; Wang, Y, 2023) |
| "Post-surgical scarring is a known cause of trabeculectomy failure." | ( Azhany, Y; Che Hamzah, J; Jaafar, H; Liza-Sharmini, AT; Low, JH; Rahman, WFWA; Yusuf, WNW, 2023) |
| "Left ventricular scar is an arrhythmic substrate that may be missed by echocardiography and diagnosed only by cardiac magnetic resonance (CMR), which is a time-consuming and expensive imaging modality." | ( Bressi, E; Brunetti, G; Calò, L; Corrado, D; Crescenzi, C; Danza, ML; De Ruvo, E; Fedele, E; Gaita, F; Golia, P; Graziano, F; Grieco, D; Monzo, L; Panattoni, G; Rebecchi, M; Stazi, A; Tatangelo, M; Zorzi, A, 2023) |
| "Fibrous scar is one of the major factors that hinder functional recovery in patients with spinal cord injury (SCI)." | ( Dai, H; Jiang, T; Li, S; Liu, K; Qiu, T; Xu, B, 2023) |
| "While scarring is thought to be mediated by a dysregulated immune response, the kinetics of cytokines and antimicrobial proteins in the tear film have not yet been characterised." | ( Bailey, R; Barton, A; Burton, MJ; Derrick, T; Faal, N; Harte, A; Holland, MJ; Joof, H; Mabey, DC; Mafuru, E; Makalo, P; Malissa, A; Massae, P; Mtuy, T; Pickering, H; Ramadhani, A; Sillah, A, 2023) |
| Excerpt | Reference |
|---|
| "A treatment for keloid overgrowth of a scar and a simple technique for rapid but careful closure of the skin have also been presented." | ( Monroe, CW, 1977) |
| "Pharmacological control of unwanted scar tissue theoretically is possible in human beings and has been proven to be practical and effective treatment in laboratory animals." | ( Peacock, EE, 1978) |
| "The epithelial tissue from the scar area after 6 weeks' treatment appeared capable of regaining a fully functional role, although it was not normal in all specimens." | ( Booyens, J; Bryer, JV; Moshal, MG; Pillay, CV, 1977) |
| "In the established hypertrophic scar or keloid, lesions of resonable size on the trunk can be treated with intralesional injections of triamcinolone only; lesions larger than 75 sq cm or facial lesions can be excised and closed or shaved and grafted, again with one or all of the above mentioned modalities being the control factor that modifies healing and prevents recurrence." | ( Ketchum, LD, 1977) |
| "Following administration of the drug to scarified skin, the proportions absorbed were very similar to those measured after application to normal skin." | ( Duchène, P; Houin, G; Izquierdo, I; Papalexiou, P; Ramis, J, 1992) |
| "Treating keloids and hypertrophic scars is difficult." | ( Tang, YW, 1992) |
| "The treatment of hypertrophic scars and keloids is a problem that has not yet been satisfactorily solved." | ( Orfanos, CE; Zouboulis, CC, 1990) |
| "Sixteen patients with gastric cicatrization due to ingestion of corrosive agents were treated over a 7 year period at Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Hospital, Pondicherry." | ( Ananthakrishnan, N; Banerjee, A; Chandrasekhar, V; Kakar, AK; Subbarao, KS, 1988) |
| "Several methods for the treatment of scar keloids have been reported." | ( Ohmori, S, 1988) |
| "An elevated type of gastric ulcer scar (EUS) (A) was noted in 8 out of 227 ulcer patients treated with cimetidine." | ( Ito, S; Kishi, S; Matsumura, M; Mizobuchi, T; Mori, H; Ohura, M; Shimizu, I, 1986) |
| "The use of several modalities for the treatment of acne scarring is advocated; these include dermabrasion, punch-transplant replacement techniques, and collagen implants." | ( Stegman, SJ; Tromovitch, TA, 1982) |
| "These scars have been treated in a variety of ways with the laser, and the results, which have been good, are reported." | ( Cromwell, TA; Henderson, DL; Mes, LG, 1984) |
| "We examined the effect of scarring on antimicrobial therapy by using a unique animal model in which both kidneys were infected to the same degree but only one kidney was scarred." | ( Miller, T, 1983) |
| "Multimodality treatment of hypertrophic scars is effective, well tolerated and can be widely used in out-patient clinics." | ( Protsenko, TV, 1984) |
| "The aims in treatment of scarred hands were to restore function and to repair unstable scars." | ( Asko-Seljavaara, S; Hytönen, M; Kilpi, ML; Sundell, B, 1980) |
| "The results of treating hypertrophic scars with urea preparations are also to be evaluated optimistically." | ( Auböck, L; Bayer, U; Kerl, H, 1981) |
| "Histological evaluation of the treated scar tissue was consistent with lathyrism." | ( Moorhead, LC, 1981) |
| "Penile scarring with prostaglandin E1 injection therapy is sporadic and unpredictable." | ( Ausmundson, S; Chen, RN; Lakin, MM; Montague, DK, 1996) |
| "Renal scarring could not be prevented in the group in which prednisolone was administered in the period during which the urethra was regularly being clamped." | ( Haraoka, M; Kubo, S; Kumazawa, J; Matsumoto, T; Takahashi, K; Tanaka, M, 1995) |
| "Common treatment of atrophic acne scars consists of invasive methods such as dermabrasion, chemopeeling, or implantation of bovine collagen." | ( Bieglmayer, C; Binder, M; Macheiner, W; Schmidt, JB, 1995) |
| "Improvement of acne scars was observed in 93% of patients treated with tretinoin iontophoresis and in 100% of the group treated with estriol iontophoresis." | ( Bieglmayer, C; Binder, M; Macheiner, W; Schmidt, JB, 1995) |
| "To prevent renal scarring, which occurs at the end stage of chronic pyelonephritis due to vesicoureteral reflux of infected urine, immediate antimicrobial treatment is reported to be essential." | ( Haraoka, M; Kubo, S; Kumazawa, J; Matsumoto, T; Takahashi, K; Tanaka, M, 1994) |
| "Acne scars may be treated surgically using procedures such as dermabrasion and dermal injections of bovine collagen or simple scar excision, scar punch elevation, or punch grafting." | ( Matsuoka, LY, 1993) |
| "Therefore we investigated if wounds and scarring could be decreased by pharmacological interference in the acute inflammatory reaction following laser therapy." | ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993) |
| "The treatments did not result in scarring or permanent pigment changes other than the ones intended." | ( Anderson, RR; DeCoste, SD; Duke, D; Gonzalez, E; Grevelink, JM; van Leeuwen, RL, 1996) |
| "Since striae are dermal scars, evaluation of this same therapy to treat striae was undertaken." | ( Ash, K; McDaniel, DH; Zukowski, M, 1996) |
| "To prevent the cicatrization of filtering blebs after glaucoma filtering surgery, subconjunctival injections of low dosage homoharringtonine were administered to 22 glaucomatous eyes (20 patients) postoperatively." | ( Li, Z; Shi, F; Shi, H, 1995) |
| "Additionally, the scars were characterized after a six-month treatment-free follow-up period." | ( Görtelmeyer, R; Maragakis, M; Michel, G; Willital, GH, 1995) |
| "A rabbit serosal scarification model was utilized to compare the ability of four drugs, previously administered peri-operatively to horses undergoing exploratory celiotomy, to prevent the development of postoperative intestinal adhesions." | ( Barker, IK; Conlon, PD; Hurtig, MB; Livesey, MA; Singer, ER, 1996) |
| "Painful scarring around peripheral nerves is a difficult treatment dilemma." | ( Colgin, S; Masear, VR, 1996) |
| "Keloids and hypertrophic scars in children are effectively treated with silicone gel sheeting." | ( Laude, TA, 1996) |
| "Chorioretinal scars were the most common eye finding in all patients and were most common in the periphery (58% of treated and 82% of historical patients)." | ( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1997) |
| "A slight improvement of the atrophic scars of the disease was noticed after local treatment with tretinoin cream, 0." | ( Bassioukas, K; Christophorou, N; Fragidou, M; Hatzis, J; Nakuci, M; Zioga, K, 1997) |
| "Of the 25 patients in whom new renal scars developed while on medical therapy 11 underwent surgery." | ( Naseer, SR; Steinhardt, GF, 1997) |
| "A percentage of scar fibroblasts undergoing apoptosis was significantly higher than that of palatal fibroblasts when they were treated with bFGF succeeding to serum starvation." | ( Funato, N; Kuroda, T; Moriyama, K; Shimokawa, H, 1997) |
| "It was designed to treat the scaring wounds of the upper limb in 5 patients with success." | ( Yu, C; Zhang, G; Zhang, L, 1997) |
| "In acute pyelonephritis renal scarring may be decreased by immediate antibiotic therapy." | ( Anderson, AE; Franco, I; Hom, D; Huang, A; Kushner, L; Palmer, LS, 1999) |
| "No difference in renal scarring was detected in animals that received no treatment versus those that received antibiotics or ibuprofen only (p>0." | ( Anderson, AE; Franco, I; Hom, D; Huang, A; Kushner, L; Palmer, LS, 1999) |
| "Renal scarring resulting from acute pyelonephritis in this rat model is not decreased by delayed treatment with antibiotics only." | ( Anderson, AE; Franco, I; Hom, D; Huang, A; Kushner, L; Palmer, LS, 1999) |
| "Corneal scars were the most common indication for treatment." | ( Fogla, R; Padmanabhan, P; Rao, SK; Seethalakshmi, G, 1999) |
| "For women with cesarean scar pregnancy who desire fertility, conservative treatment using MTX is an excellent choice." | ( Cheng, WC; Chuang, J; Hwang, JL; Lee, C; Seow, KM; Tsai, YL, 2000) |
| "Treatment of atrophic acne scars is difficult and generally unsatisfactory." | ( Akçali, C; Erbağci, Z, 2000) |
| "To compare the prevalence of scarring following initial treatment with antibiotics administered intravenously for 10 or three days." | ( Benador, D; Engel-Bicik, I; Girardin, E; Mermillod, B; Nadal, D; Neuhaus, TJ; Papazyan, JP; Slosman, D; Willi, UV, 2001) |
| "Treatment of acne scarring is a challenging problem for dermatologists and cosmetic surgeons." | ( Weinstein, C, 1999) |
| "Only a combination of anti-scarring treatments including (i) injection of the more potent PH inhibitor [2,2'-bipyridine]-5,5'-dicarboxylic acid (BPY-DCA), (ii) selective inhibition of fibroblast proliferation and ECM production by 8-Br-cAMP, and (iii) continuous application of BPY-DCA, reduced the lesion-induced BM significantly." | ( Hermanns, S; Müller, HW; Reiprich, P, 2001) |
| "Histologic study of the scars showed they were thicker and had less cellularity in the treated animals than in the control animals." | ( Bowers, D; Cohen, WR; Dutta, D; McKenzie, D; Wheeless, CR, 2001) |
| "There are numerous forms of acne scarring and it is important to be aware of these as patients who are developing scarring merit early effective therapy." | ( Layton, AM, 2001) |
| "Thirteen patients were treated for acne scars, two patients for wrinkles and one patient for chicken pox scar." | ( Goh, CL; Khoo, L, 2002) |
| "One half of the patient's scar was treated with motor-powered diamond fraise dermabrasion and the other half was treated with manual dermabrasion with medium-grade drywall sanding screen." | ( Boyd, CM; Dunn, RL; Fader, DJ; Gillard, M; Johnson, TM; Wang, TS, 2002) |
| "Acne scarring is a common complication of acne and yet no appropriate and effective single treatment modality has been developed." | ( Chung, WG; Kwahck, H; Lee, JB; Lee, KH, 2002) |
| "The laser photocoagulation scar was measured with an image analyzer immediately and once a year after the treatment." | ( Harino, S; Iwahashi, Y; Matsuda, S; Nagaya, C, 2002) |
| "Histologically, less scar tissue was observed at the sclerostomy site with inhibition of MMP, compared with vehicle treatment." | ( Khaw, PT; Mead, AL; Wong, TT, 2003) |
| "The microscopic multifocal necrosis and scarring are modulated by chronic AT(1) receptor blockade in experimental cardiomyopathy; thus, we also wished to rationalize the spectromicroscopic differences among control, untreated cardiomyopathic (CMP), and losartan-treated cardiomyopathic (LOS) hearts according to the pathogenesis of experimental cardiomyopathy." | ( Dixon, IM; Gough, KM; Rak, M; Wiens, R; Zelinski, D, 2003) |
| "Physician and patient acne scar ratings were performed at baseline and at 6 months after the last treatment." | ( Goldberg, DJ; Hussain, M; Rogachefsky, AS, 2003) |
| "Interstitial scarring was significantly less in treated rats (p < 0." | ( Allen, AR; Bhangal, G; Cook, HT; Khan, SB; Lobb, RR; Pusey, CD; Smith, J, 2003) |
| "At 5 weeks, greater scar elastin content and better LV function was noted with cell transplantation or ACE inhibitor therapy compared with control rats (p < 0." | ( Fujii, T; Li, RK; Matsubayashi, K; Mickle, DA; Ohno, N; Ozawa, T; Shiono, N; Weisel, RD; Yau, TM, 2003) |
| "Hypertrophic scar and keloid are common and difficult to treat diseases in plastic surgery." | ( Cao, YL; Liu, W; Wang, DR, 2004) |
| "One of the cesarean scar pregnancies was treated by transvaginally guided potassium chloride injection, and the other was treated via transabdominally guided dilation and evacuation." | ( Benson, CB; Doubilet, PM; Frates, MC; Ginsburg, E, 2004) |
| "Marked clinical improvement of the scars and successful treatment of the acne excoriée were achieved with this combination approach." | ( Alster, TS; Bowes, LE, 2004) |
| "The 301 patients with hypertrophic scar were randomly divided into two groups: one treated with elastic cloth paste (including silicone) contained in Dan-shen root with azone, and the another treated with only elastic cloth paste (including silicone)." | ( Chen, GS; Chen, J; Dong, HL; Han, CM; Qi, FZ, 2004) |
| "Significantly less fibrous scar formation was observed in suramin-treated muscles than in sham-injected muscles." | ( Chan, YS; Foster, W; Fu, FH; Huard, J; Li, Y, 2005) |
| "For atrophic scars, different types of lasers represent modern treatment modalities with satisfactory results." | ( Berman, B; Ramirez, CC; Villa, AM, 2004) |
| "To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS)." | ( Khaw, PT; Mead, AL; Wong, TT, 2005) |
| "Recently, conservative treatment of scar pregnancy with locally and/or systemically administered methotrexate (MTX) has been reported." | ( Chisaka, H; Okamura, K; Senoo, M; Sugawara, J; Yaegashi, N, 2005) |
| "In addition, less hypertrophic scar development was observed in treated wound at 90 days (3 in 16 cases, 20." | ( Cao, YL; Cui, L; Liu, W; Qian, YL; Yang, GH; Yang, J, 2005) |
| "We conclude that the fibrous lesion scar plays a pivotal role as a growth barrier for regenerating axons in adult spinal cord and that a delay in fibrotic scarring by local inhibition of collagen biosynthesis and basement membrane deposition is a promising and unique therapeutic strategy for treating human spinal trauma." | ( Duis, S; Hamers, FP; Hermanns, S; Klapka, N; Masanneck, C; Müller, D; Müller, HW; Straten, G; Zuschratter, W, 2005) |
| "Acne scars in three patients were treated with focal 95% TCA by serial application." | ( Howard, MS; Kent, DE; Lane, JE; Yug, A, 2006) |
| "Effective treatment of facial acne scarring presents a major challenge." | ( Lipper, GM; Perez, M, 2006) |
| "Ten subjects with a variety of acne scars were treated with calcium hydroxylapatite filler." | ( Amin, S; Goldberg, DJ; Hussain, M, 2006) |
| "Saucerized acne scars responded to treatment; ice-pick scars did not." | ( Amin, S; Goldberg, DJ; Hussain, M, 2006) |
| "Renal scar was significant in the groups treated with MB alone or MB + CIP combination compared with untreated or antibiotic only groups." | ( Aksu, B; Aydin, S; Ayvaz, S; Durmus-Altun, G; Gurcan, S; Inan, M; Kanter, M; Oz Puyan, F; Pul, M; Uzun, H, 2007) |
| "We report on four cases of caesarean scar pregnancy with different modes of treatment--expectant, surgical, systemic medical, and local medical." | ( Yan, CM, 2007) |
| "By excising the scars and resurfacing with Integra, we present and describe a novel technique for treating the visible stigmata of previous DSH." | ( Canal, AC; Ismail, A; Jarvi, K, 2008) |
| "Therapeutic intervention for postacne scarring has historically been limited by the considerable morbidity of most treatments for only marginal disease improvement." | ( Baron, JA; Goodman, GJ, 2007) |
| "To determine whether myocardial scarring, quantified using late gadolinium enhancement-cardiovascular magnetic resonance (LGE-CMR), predicts response to cardiac resynchronization therapy (CRT)." | ( Chalil, S; Foley, PW; Frenneaux, MP; Leyva, F; Muyhaldeen, SA; Patel, KC; Smith, RE; Yousef, ZR, 2007) |
| "Traditional scar revision has addressed issues of thickness with intralesional corticosteroids, superficial contours with dermabrasion or laser resurfacing, and postrepair erythema with hemoglobin-targeted laser therapy." | ( Cohen, JL; Kasper, DA; Morganroth, GS; Saxena, A, 2008) |
| "Acneiform scarring after severe episodes of acne is a common cosmetic concern, treatable by a variety of modalities with varying degrees of success." | ( Bernstein, LJ; Brightman, L; Chapas, AM; Daniel, D; Geronemus, RG; Hale, E; Sukal, S, 2008) |
| "To describe a case of cesarean scar pregnancy treated successfully by endoscopic technique and medical therapy." | ( Antoniou, N; Korkontzelos, I; Kosmas, I; Souliotis, D; Tsirkas, P, 2008) |
| "Four of the cases had the scar associated with the flying bird incision, and one case required no treatment after the primary repair." | ( Ino, K; Kiyokawa, K; Koga, N; Morinaga, K; Rikimaru, H; Takahashi, N, 2008) |
| "The authors present a case of ice pick scars forming in the nasal alar grooves of a patient who was treated with a 1064-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser for facial telangiectasias." | ( Babcock, MJ; Cohen, JL, 2009) |
| "For dyspigmentation, the half of the scar treated with the suture had a better outcome (mean=3." | ( Kouba, DJ; Moy, RL; Tierney, EP, 2009) |
| "Improvement of acne scarring was evaluated at 1 and 3 months post-treatment." | ( Elkeeb, L; MacFalls, HT; Ortiz, AE; Tournas, JA; Truitt, AK; Walgrave, SE; Zachary, CB; Zelickson, BD, 2009) |
| "Three cases of cesarean scar pregnancy successfully treated with methotrexate are described." | ( Hisamoto, K; Kanagawa, T; Kimura, T; Mabuchi, S; Muraji, M; Muranishi, M; Nishio, Y, 2009) |
| "Greater insight into the pathology of scars may translate into non surgical treatments in the future and further work in myofibroblast biology will eventually result in efficient pharmacological tools, improving the evolution of healing and scar formation." | ( Abdallah Hajj Hussein, I; Atiyeh, BS; Dibo, SA; El Kahi, CG; Jurjus, A; Jurjus, R, 2009) |
| "Acne scarring is a common complication of acne but no effective single treatment modality has been developed." | ( Kim, HJ; Kim, TG; Kwon, YS; Lee, JH; Park, JM, 2009) |
| "To prevent scar formation numerous materials and methods have been employed such as non steroidal anti-inflammatory drugs (NSAIDs), Gelfoam, Oxiplex, Gore-tex, carboxymethil cellulose, Adcon-L, autogenous adipose grefting, mitomisin, and radiotherapy have been investigating for a long time, but only moderate success has been obtained." | ( Celik, B; Cemil, B; Ceviker, N; Durdag, E; Erdem, O; Kurt, G, 2009) |
| "To present a case of cesarean scar ectopic pregnancy (CSEP) successfully diagnosed and treated with a laparoscopic local injection of 100 mg etoposide under transvaginal ultrasound assistance." | ( Chen, CH; Liu, WM; Wang, PH, 2009) |
| "We analysed the effect of scar-suppressing treatment (anti-scarring treatment; AST) on augmenting axonal regeneration of various neuronal populations following spinal cord injury (SCI) in adult rat." | ( Brazda, N; Müller, HW; Schiwy, N, 2009) |
| "Remodeling of scar tissue with renewal and reorganization of collagen fibers in the dermis was noted two weeks post-treatment." | ( Cerino, ME; Vasily, DB; Zeina, ST; Ziselman, EM, 2009) |
| "Severe scarring acne is frequently treated with isotretinoin." | ( Beer, K; Oakley, H; Waibel, J, 2009) |
| "Four women diagnosed with a caesarean scar pregnancy in our hospital between 1996 and 2007 were treated with local or systemic methotrexate and had a steady decline of the serum beta-hCG level." | ( Brölmann, HA; de Vaate, AJ; Huirne, JA; Schats, R; van der Slikke, JW; Wouters, MG, 2010) |
| "Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar." | ( Basdag, B; Magarakis, M; Manson, PN; Rosson, GD; Shridharani, SM; Singh, NK, 2010) |
| "Bulous and scarring were observed in skin treated with the higher fluence during the recovery period." | ( Chen, CC; Fang, CL; Fang, JY; Huang, CM; Lee, WR; Pan, TL; Wang, PW, 2010) |
| "Mitomycin C (MMC) could also reduce the scar formation after surgery, but cytotoxicity and the administrative pathway prevent its application." | ( Cao, X; Liu, J; Ni, B; Yang, J; Zhou, W; Zhu, L, 2010) |
| "Acne scarring is common but difficult to treat." | ( Jansen, T; Podda, M, 2010) |
| "Mitomycin C (MMC) is used clinically to treat corneal scarring in human patients." | ( Buss, DG; Giuliano, EA; Mohan, RR; Sharma, A, 2010) |
| "Fifty-nine patients with atrophic scars (caused by acne, trauma, herpes zoster, and burns) were treated with fractional photothermolysis using either Fraxel™ SR 750 or Fraxel™ SR 1500 instruments." | ( Bak, H; Bang, JS; Chang, SE; Choi, JH; Kim, BJ; Kim, MN; Lee, MW; Lee, SY; Moon, KC; Park, GH; Rhee, DY, 2011) |
| "Following scar revision by surgery or CO(2) laser ablation on bilateral areas, one scar was treated daily by the patient at home with non-thermal, non-ablative NIR LED (805 nm at 30 mW/cm(2)) for 30 days." | ( Barolet, D; Boucher, A, 2010) |
| "Treatments for corneal scarring,ocular protection, and amblyopia were achieved by fitting a scleral lens with a unique piggyback combination involving a cosmetic soft contact lens." | ( Carrasquillo, K; Michaud, L, 2010) |
| "Treated piglets revealed scars exhibiting less dense fibrosis with predominance of fibroadipose tissue and less collagen proliferation." | ( Arfelli, E; de Araujo, S; de Paola, AA; dos Santos, LF; Fenelon, G; Franco, M; Nascimento, T; Okada, M, 2011) |
| "Decreasing the scar size and the low cost are two promising aspects in introducing 5% TCA cream as a potential alternative for intralesional glucantime in the treatment of CL." | ( Ali, N; Ali, NM; Elaheh, H; Fariba, J, 2012) |
| "The treatment of atrophic scars is difficult and dermal filler materials provide a simple alternative with immediate results." | ( Hasson, A; Romero, WA, 2010) |
| "The collagen scar, physical barrier to axon regeneration, was noticeably diminished by agmatine treatment at 4 weeks after SCI (P = 0." | ( Kim, JH; Lee, JE; Lee, WT; Lee, YW; Park, KA; Park, SH; Park, YM, 2011) |
| "Acne scars are difficult to treat." | ( Bhardwaj, D; Khunger, M; Khunger, N, 2011) |
| "Treatment of ice pick acne scars with the CROSS technique using high strength 100% TCA is a safe, minimally invasive, efficacious, and cost-effective technique in darker skin." | ( Bhardwaj, D; Khunger, M; Khunger, N, 2011) |
| "Acne scarring is common but surprisingly difficult to treat." | ( Bassiouny, DA; El-Komy, MH; El-Tobshy, SA; Ramadan, SA, 2011) |
| "We hypothesize that scar quantification by LGE-CMR may prove a valuable risk stratification tool for the occurrence of ventricular arrhythmias, which may have implications for patient selection for ICD therapy." | ( Carroll, N; Curzen, NP; Harden, SP; Morgan, JM; Murday, DC; Peebles, CR; Roberts, PR; Scott, PA, 2011) |
| "Twelve patients with atrophic scar or fibrofatty tissue secondary to residual hemangiomas or with scarring after surgery of haemangioma were treated with one or two sessions of ablative fractional YSGG laser at 2." | ( Alcántara González, J; Boixeda, P; López Gutiérrez, JC; Olasolo, PJ; Truchuelo Díez, MT, 2012) |
| "New approaches to wound/scar therapy are discussed." | ( Billet, F; Coulomb, B; Desmoulière, A; Micallef, L; Sarrazy, V, 2011) |
| "It is important that scar mechanobiology be understood from the perspective of the extracellular matrix and extracellular fluid, in order to analyze mechanotransduction pathways and develop new strategies for scar prevention and treatment." | ( Ogawa, R, 2011) |
| "Treatment of this mixed condition (scarring and active acne) with a single device is reliable, with a favorable safety profile and a high degree of patient acceptance." | ( Cornejo, P; Isarría, MJ; Moraga, JM; Muñoz, E; Royo de la Torre, J, 2011) |
| "Surgical scar remodelling and clinical improvement may be accomplished via ALA/MAL-PDT, but may require repeated treatment sessions." | ( Anderson, RR; Izikson, L; Sakamoto, FH; Tannous, Z; Zurakowski, D, 2012) |
| "Epidural scar thickness and the density were significantly lower in the animals treated with tacrolimus than those of the control group." | ( Albayrak, B; Demir, N; Gulsen, I; Ismailoglu, O; Tanriover, G, 2011) |
| "Hypopigmented scarring is a challenging condition to treat, with current treatments showing limited efficacy and temporary results." | ( Fabi, SG; Fitzpatrick, R; Massaki, AB, 2012) |
| "Fourteen patients with hypopigmented scars were treated with a mean of 4." | ( Fabi, SG; Fitzpatrick, R; Massaki, AB, 2012) |
| "The diagnosis and treatment of cesarean scar pregnancy (CSP) is challenging." | ( Arslan, AA; Monteagudo, A; Pineda, G; Santos, R; Timor-Tritsch, IE; Tsymbal, T, 2012) |
| "Glial scar formation is the major impedance to axonal regrowth after spinal cord injury (SCI), and scar-modulating treatments have become a leading therapeutic goal for SCI treatment." | ( Aoki, I; Fukuyama, R; Hara, M; Ito, M; Kim, SU; Lee, HJ; Motomura, K; Natsume, A; Nishimura, Y; Saga, T; Sumiyoshi, N; Wakabayashi, T, 2013) |
| "We hypothesize that scar quantification by LGE-CMR may be more specific for SCD than non-SCD, and may prove a valuable tool for the selection of patients for ICD therapy." | ( Curzen, NP; Harden, SP; Morgan, JM; Murday, DC; Peebles, CR; Rosengarten, JA; Scott, PA, 2013) |
| "Acne and acne scars can be treated more effectively by concomitant use of an infrared fractional laser with low-dose isotretinoin with reduced MTZ densities." | ( Hann, SK; Kim, CW; Kim, KH; Kim, KJ; Kwon, IH; Lee, GS; Park, EJ; Yoon, JH, 2014) |
| "Pregnancy in a caesarean section scar is the rarest form of an ectopic pregnancy English language literature up to 2007 reports only about 70 cases, including three cases treated laparoscopically." | ( Nowakowski, B; Spychała, P, 2012) |
| "Parameters measured included scar size, color, and pliability (consistency/hardness), as well as patients' and physicians' subjective assessments of treatment efficacy and tolerability." | ( Simon, J; Willital, GH, 2013) |
| "Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects." | ( Bühren, J; Ciufo, D; DeMagistris, M; Hindman, HB; Huxlin, KR; Jeon, KI; MacRae, S; Phipps, RP; Sime, PJ, 2013) |
| "The Focal Acne Scar Treatment technique is an effective method of improving the appearance of atrophic acne scars." | ( Schweiger, ES; Sundick, L, 2013) |
| "Twenty Thai subjects with atrophic acne scars received three split-face monthly treatments, one side with fractional bipolar RF and the other with fractional erbium-doped glass." | ( Rongsaard, N; Rummaneethorn, P, 2014) |
| "Mean Vancouver Scar Scale scores were significantly lower after laser treatment (p < ." | ( Kang, KH; Oh, IY; Park, KY; Park, SJ; Seo, SJ, 2013) |
| "Despite the reduced scar width, DSCG treatment did not affect the breaking strength of the healed tissue." | ( Chen, L; DiPietro, LA; Ranzer, MJ; Schrementi, ME; Wilgus, TA, 2014) |
| "Scar quality was evaluated by Vancouver scar scale (VSS) in two groups of female thyroidectomy patients (control, n = 11; rhEGF-treated, n = 10)." | ( Chung, WY; Jeong, JJ; Kang, SW; Lee, JH; Nam, KH; Shin, JU, 2015) |
| "Fibrotic scar formation in def+/- is blocked by the over-expression of Def, by the loss-of-function of p53, and by treatment with anti-inflammation drug dexamethasone or TGFβ-signalling inhibitor SB431542." | ( Chen, J; Peng, J; Xiong, JW; Zhu, Z, 2014) |
| "Atrophic scars represent a loss of collagen and a challenging reconstructive dilemma with disappointing traditional treatments." | ( Ozog, D; Rkein, A; Waibel, JS, 2014) |
| "Between 2008 and 2012, 35 facial scars (n=35) on 26 patients (n=26) were treated by autologous lipofilling." | ( Alharbi, Z; Baroncini, A; Pallua, N; Stromps, JP, 2014) |
| "Fibrotic disciform scars represent the end-stage of wet age-related macular degeneration (AMD) and ophthalmologists tend not to treat them." | ( Coco, RM; Sala-Puigdollers, A, 2014) |
| "Treatment with NP-siRNAs targeting key scarring genes or an anti-inflammatory steroid reduced corneal haze and SMA mRNA and protein." | ( Gibson, DJ; Lewin, AS; Pi, L; Robinson, P; Schultz, G; Sriram, S; Tuli, S, 2014) |
| "Forty-five patients with atrophic acne scars were randomly assigned to 3 equal groups; Group A received intradermal injection of PRP, Group B received chemical reconstruction of skin scars technique with TCA 100%, and Group C was treated by combined skin needling and PRP." | ( Alakad, R; Helmy, A; Nasr, M; Nofal, A; Nofal, E, 2014) |
| "Thirty-one Korean patients with acne scars and enlarged pores received 4 consecutive fractional RF treatments at 3-week intervals." | ( Chang, SE; Kim, JE; Kim, JK; Ko, JY; Lee, HW; Lee, MW; Moon, SH, 2014) |
| "Renal scar score was declined in "ceftriaxone + ketoprofen" group and "ceftriaxone + methylprednisolone" group compared with no-treatment group on 10th week of the study (P = 0." | ( Arslansoyu Çamlar, S; Bahat Özdoğan, E; Cobanoğlu, Ü; Doğan, I; Imamoğlu, M; Özdemir, T; Sönmez, B; Tosun, İ, 2014) |
| "A total of 10 patients with 14 keloid scars resistant to conventional treatments were enrolled in a retrospective study between October 2007 and October 2013." | ( Bénateau, H; Chopinaud, M; Dompmartin, A; Gourio, C; Labbé, D; Pham, AD; Verneuil, L, 2014) |
| "Results show reduced glial scar formation, less macrophage activation, and signs indicative of axonal regeneration beyond the glial scar in treated animals." | ( Ohlsson, M; Ridderström, M, 2014) |
| "Because acne scarring is associated with substantially reduced quality of life, early initiation of effective treatment is desirable." | ( Chang, SE; Kim, HW; Kim, JE; Ko, JY; Ro, YS, 2014) |
| "Ablative CO2 fractional laser treatment for acne scarring seems to be safe regardless of isotretinoin use (10-60 mg/d)." | ( Chang, SE; Kim, HW; Kim, JE; Ko, JY; Ro, YS, 2014) |
| "Corticosteroids may be beneficial in treating vocal fold scarring." | ( Kosinski, AM; Panitch, A; Pothen, JM; Sivasankar, MP, 2015) |
| "For this purpose, cultured pathological scar fibroblasts were treated with various concentrations of Res (10, 50, and, 100 µmol/l), and the morphological changes in target cells were studied using scanning electron microscopy (SEM)." | ( Ding, JC; Tang, ZM; Zhai, XX, 2015) |
| "Acne scarring is a common sequela of acne for which no single treatment method is uniformly effective." | ( Agarwal, N; Gupta, LK; Khare, AK; Kuldeep, CM; Mittal, A, 2015) |
| "Patients with predominantly boxcar scars and higher pretreatment scar severity were associated with better treatment outcomes." | ( Agarwal, N; Gupta, LK; Khare, AK; Kuldeep, CM; Mittal, A, 2015) |
| "The presence of scar reduces the likelihood of a response to medical therapy and to cardiac resynchronization therapy in heart failure." | ( Kramer, CM, 2015) |
| "Renal scarring was noted in only a small number of children at study entry and no reduction in scarring was noted between the placebo and the treated groups." | ( Mathews, R; Mattoo, TK, 2015) |
| "There was less scar contraction in wounds treated with the topical antibiotic compared with the silver-based dressing (mean ± SD = 25." | ( Chung, WT; McClain, SA; Osman, N; Raut, V; Singer, AJ; Toussaint, J, 2015) |
| "Atrophic acne scars are a common and psychologically devastating sequela of acne vulgaris that are refractory to the vast majority of topical treatments." | ( Moy, RL; Seidel, R, 2015) |
| "Despite laser therapy, permanent scarring of the nasal tip was prominent at the 18-month follow-up." | ( Hwang, K; Kim, JH; Kim, SK, 2015) |
| "Many different algorithms for scar prophylaxis and treatment have been presented in the literature." | ( Damsgaard, TE; Hammer-Hansen, N; Rødgaard, JC, 2015) |
| "The collagen content of the nerve scarring at week 12 in the treatment group was apparently less than the control group (P < 0." | ( Jiang, YT; Jiao, JB; Li, CY; Ling, L; Liu, XF; Xue, JW; Yang, G; Yin, WT, 2016) |
| "Thus, TGF-β3 may offer a scar-reducing therapy for acute and chronic wounds and fibrosing disorders." | ( Falanga, V; Lichtman, MK; Otero-Vinas, M, 2016) |
| "2012, 9 cases with large area scar on forehead received treatment of adjacent scalp expanded flap combined with JPL hair removal." | ( Hongwei, Y; Hua, L; Hui, G; Li, C; Li, Z; Peng, W; Xia, Y, 2015) |
| "However, the appearance of a scar and its treatment depend on multiple factors and on the experience of the therapist and the options available." | ( Martínez-Carpio, PA; Trelles, MA, 2016) |
| "Cesarean scar pregnancy and cervical pregnancy are unrelated forms of pathological pregnancies carrying significant diagnostic and treatment challenges, with a wide range of treatment effectiveness and complication rates ranging from 10% to 62%." | ( Bennett, TA; Foley, C; Kaelin Agten, A; Monteagudo, A; Ramos, J; Timor-Tritsch, IE, 2016) |
| "Surgical scars are best treated with a combination approach to address various features of the scar." | ( Cohen, JL; Eilers, RE; Ortiz, AE; Ross, EV, 2016) |
| "As the treatment modalities to manage scars continue to evolve, further characterization of the role of elastin in the skin and in scar formation is merited." | ( Brauer, JA; Cohen, BE; Geronemus, RG; McDaniel, DH, 2017) |
| "Successful treatment of acne scars is challenging." | ( McGraw, TA; Taylor, MB; Zaleski-Larsen, L, 2017) |
| "These data suggest that progressive scarring in OMMP results from ALDH/RA fibroblast autoregulation, that the ALDH1 subfamily has a central role in immune-mediated ocular mucosal scarring, and that ALDH inhibition with disulfiram is a potential and readily translatable antifibrotic therapy." | ( Abraham, DJ; Ahadome, SD; Calder, VL; Daniels, JT; Dart, JK; Norman, JT; Ponticos, M; Rayapureddi, S; Saban, DR; Saw, VP, 2016) |
| "After 6 months treatment, scar counts remained stable with A/BPO while increasing by approximately 25% with vehicle (mean scar count 11." | ( Bissonnette, R; Dreno, B; Martel, P; Rivier, M; Tan, J, 2017) |
| "To treat persistent hypertrophic scars, local injection of drugs composed of steroids, calcium channel blockers (CCBs), and interferon might be a good method." | ( Chuang, SS; Hsiao, YC; Yang, JY; Yang, SY, 2017) |
| "Human scar-derived dermal fibroblasts (HSFs) were treated with TGF-β alone, TGF-β plus bFGF, and TGF-β plus cell surface expression of epimorphin." | ( Adachi, N; Hagiwara-Chatani, N; Hirai, Y; Horigome, T; Kido, T; Nakashima, A; Shirai, K; Takumi, S; Yano, H, 2017) |
| "Pitted acne scars of all types remain notoriously challenging to treat with no satisfactory treatment modality, particularly true for darker Fitzpatrick skin types such as Indian skin." | ( Gatne, V; Goel, A, 2017) |
| "The mTOR and 70S6K in pathological scar and normal skin fibroblasts were detected by immunofluorescence following treatment with different concentrations of Res." | ( Ding, JC; Tang, ZM; Zhai, XX, 2017) |
| "In this prospective double-blind split-scar study, the authors treated each half scar of 26 women with either tranilast 8% liposomal gel or tranilast-free liposomal gel (placebo)." | ( Artzi, O; Kohavi, L; Sprecher, E; Zur, E, 2017) |
| "NAFL treatment for acne scarring appears to be well tolerated within 1 month of completing isotretinoin treatment." | ( Saluja, SS; Smart, DR; Summers, EM; Tristani-Firouzi, P; Walker, ML, 2017) |
| "In contrast to untreated iLTS scar fibroblasts, collagen gene expression, protein production, metabolic rate, and proliferation were significantly reduced." | ( Ding, D; Duvvuri, M; Feeley, M; Hillel, AT; Motz, KM; Murphy, MK; Yin, L, 2018) |
| "Larger epineurial scar thickness was observed in the control groups compared with the treatment groups at 4, 8 and 12 weeks following surgery." | ( Bi, W; Hu, M; Huang, H; Li, R; Liu, H; Song, W; Tan, X; Wang, C; Wen, W; Yan, R; Zhang, F; Zhang, Y, 2018) |
| "Available methods for treating acne scars have varying degrees of effectiveness." | ( Casabona, G, 2018) |
| "Acne scarring has been a challenge to treat." | ( Alaa, H; El Khayyat, MAM; Moftah, NH; Ragai, MH, 2018) |
| "The image of scar was taken by Antrea 3D camera before the treatment, VSS, and UN4P were also applied for scar evaluation." | ( Hong, L; Shi, K; Yu, J; Zhang, N; Zhao, J, 2018) |
| "The high incidence of hypertrophic scar formation is one of the many challenges to treating deep partial-thickness burns." | ( Dorati, R; Fourcaudot, AB; Leung, KP; Medina, JL; Sebastian, EA, 2019) |
| "Hypertrophic scarring is a common condition in the Chinese population; however, there are currently no satisfactory drugs to treat the disorder." | ( Guo, S; Lei, L; Ma, X; Song, B; Song, Y; Su, Y; Yu, Z, 2018) |
| "Vocal fold scarring remains a major treatment challenge, and scar prevention without residual lesions remains a dilemma." | ( Gong, T; Jiang, JJ; Kang, J; Lamb, JJ; Zhang, C, 2019) |
| " Detecting renal scar is important in pediatric patients with vesicoureteral reflux (VUR) for deciding on treatment option." | ( Bayram, G; Karabulut, B; Ozcift, B; Oztorun, CI; Tiryaki, TH, 2019) |
| "Burn scar treatment persists as an unsolved problem, involving thousands of affected patients disfigured for life." | ( Agaoglu, G; Jawad, MA; Onur Erol, O, 2019) |
| "Laser treatment reduced scar intensity and attenuated skin irregularities and hyperpigmentation." | ( Agaoglu, G; Jawad, MA; Onur Erol, O, 2019) |
| "New early endoscopic approaches (scar lysis and mucosal reconstitution with autologous grafting over an endoluminal stent), when combined with targeted medical therapy aimed at components of mucosal airway inflammation (local corticosteroids and systemic Azithromycin targeting IL-17A), may have potential to limit chronic cicatricial complications." | ( Dion, GR; Gelbard, A; Jayawardena, A; Lowery, AS; McGrane, S; Summitt, JB; Wootten, C, 2019) |
| "By contrast, median qualitative acne scar scores were the same for both treatment groups at baseline and did not significantly change following either treatment." | ( Afra, TP; Dogra, S; Kumar, A; Narang, T; Razmi T, M, 2019) |
| "Hyperpigmentation occurred in 4 scars in both the half treated with manual dermabrasion and the half treated with laser resurfacing; however, it had resolved by the end of the sixth month in all 4 scars." | ( Srivalli, N; Taher, M; Yusuf, M, 2019) |
| "Avoidance of acne scars with early and aggressive treatment is a more efficient and cost-effective option than subsequent treatment." | ( Baldwin, HE; Marson, JW, 2019) |
| "Cryotherapy has been shown to be a scarless treatment modality for dermal lesions; however, there are limited data addressing the effect of cryotherapy on vocal fold tissue." | ( Gong, T; Jiang, JJ; Kang, J; Lou, Z; Scholp, A; Zhang, C, 2019) |
| "Myocardial scars are equally best visualized with delay time of 5 and 7 min post contrast administration." | ( Goto, Y; Hamdy, A; Kitagawa, K; Nagasawa, N; Nakamura, S; Sakuma, H; Takafuji, M; Yamada, A, 2019) |
| "Treatment options for atrophic acne scars include the use of various energy-based devices (EBDs) and dermal fillers." | ( Artzi, O; Bar Ilan, E; Cohen, S; Isman, G; Koren, A; Salameh, F; Sprecher, E, 2019) |
| "Sixteen patients with hyperpigmented scars underwent 3 to 8 treatment sessions at 3- to 6-week intervals with the 1,064-nm Nd:YAG picosecond laser (PicoWay, Candela, Resolve handpiece)." | ( Artzi, O; Cohen, S; Koren, A; Niv, R, 2019) |
| "Treatment of cesarean scar pregnancy with a combination of systemic and local methotrexate was effective and safe." | ( Amir, M; Bruchim, I; Hallak, M; Naeh, A; Shalom-Paz, E; Shrim, A, 2019) |
| "PFD injection into the scarred VF is a potentially promising novel antifibrotic treatment." | ( Kodama, H; Kumai, Y; Miyamaru, S; Nishimoto, K; Onoue, S; Orita, Y; Yamada, T, 2020) |
| "Reductions in atrophic acne scars and acne lesions observed after 24 weeks of treatment with A0." | ( Barankin, B; Bissonnette, R; Chavda, R; Dréno, B; Gagné-Henley, A; Kerrouche, N; Lynde, C; Tan, J, 2019) |
| "The healing rate and scar formation were followed after treatment with Panax notoginseng saponins." | ( Huo, QL; Liu, BQ; Men, SY; Shi, L; Yan, Y; Yang, CC; Yu, W, 2020) |
| "Inpatients who had scar on DMSA scan, the mean UIL-8 and UIL-6levels were significantly high before and after treatment." | ( Ghaffari, J; Mahdavi, MR; Mohammadi, GH; Mohammadjafari, H, 2019) |
| "We foundout that patients with scar had sustained high levels of biomarkersbefore and after treatment." | ( Ghaffari, J; Mahdavi, MR; Mohammadi, GH; Mohammadjafari, H, 2019) |
| "Therapies for postacne scarring act through modulation of elastin and collagen, and collagen III might therefore represent a biomarker of treatment effectiveness." | ( Abdel Motaleb, AA; Abdel-Magiud, EM; Bakr, RM; Ismail, SA; Kamel-ElSayed, S; Makboul, M; Sayed, SK; Taha, EA, 2020) |
| "Patients with facial acne scars were treated with a picosecond alexandrite laser in three sessions at 4- to 6-week intervals and followed up for 2 months." | ( Fang, J; Lin, T; Wu, Q; Zhang, M, 2020) |
| "Treatment of cesarean scar pregnancy is based on clinical context." | ( Aubrey, C; Mills, G; Omand, A; Tankel, J, 2020) |
| "Human epidural scar fibroblasts were isolated from surgical specimens and treated with allicin at a gradient of concentrations." | ( Cai, J; Feng, XM; Sun, HH; Wang, JC; Zhu, SL, 2020) |
| "Graft survival, scar quality, and patient satisfaction were evaluated and compared with 10 patients treated with conventional FTSGs." | ( Choi, YS; Kim, DW; You, HJ, 2020) |
| "The mean Scar Global Assessment score significantly decreased after 3 sessions of combination treatment (n = 71)." | ( Jung, JY; Kim, J; Lee, JH; Lee, WJ; Lee, YI, 2020) |
| "TSSgo scar innovative treatment showed long-term efficacy in comparison with silicon gel in terms of improved scar tissue texture, pigmentation, pliability and height." | ( Calabrese, S; Fisher, AD; Lo Russo, G; Maggi, M; Tanini, S, 2020) |
| "The Caesarean scar mass was followed with trans-vaginal ultrasound and regressed within 2 months to about 1 year post treatment." | ( Darwish, HS; Habash, MY; Habash, YH, 2020) |
| "In this paper, we describe a case of scarring alopecia due to LE that stopped responding to a treatment that had been effective for years." | ( Bello, JA; Cabo, F; Fernandez-Flores, A; Hermosa-Gelbard, A; Pérez, A, 2020) |
| "Laser procedures for acne and acne scars have traditionally been postponed for at least 6 to 8 months after the end of systemic isotretinoin therapy." | ( Gold, MH; Ikonnikova, EV; Kruglova, LS; Manturova, NE, 2020) |
| "For Caesarean scar pregnancies (CSP) it is uncertain whether there is a difference in success rates, complications, or adverse events between UAE/UACE and administration of systemic MTX before suction curettage (low-quality evidence)." | ( Fu, J; Hu, Y; Huang, W; Long, Y; Shen, L; Zhu, H, 2020) |
| "Histologic examination of scar tissue punch biopsies (hematoxylin-eosin staining) before and after the treatment was performed as well as magnetic resonance scan with contrast." | ( Klinger, M; Marazzi, M; Torre, M; Vigo, D, 2020) |
| "Stem cell therapy holds promises for treating corneal scarring." | ( Cao, J; Chen, J; Cui, Z; Guo, Y; Li, Z; Liu, H; Liu, S; Wang, P; Xie, M; Xue, Y; Yu, Q; Zeng, Q; Zhang, J; Zhong, J; Zhu, D, 2020) |
| "This study enrolled hand scar patients who received treatment in our hospital between May 2018 and April 2019." | ( Chen, S; Liu, H; Xu, H; Zhang, J; Zhou, Z; Zhu, X, 2021) |
| "We reported two cases of cesarean scar pregnancy (CSP) treated in Strasbourg's University Hospital between 2016 and 2018 and carried out an updated literature review concerning their treatment." | ( Akladios, C; Gabriele, V; Garbin, O; Host, A; Lecointre, L; Legris, ML, 2021) |
| "Successful treatment of acne scars in ethnic skin requires procedures that are safe and effective with a low incidence of hyper or hypopigmentation postoperatively." | ( Koron, N; Taylor, MB, 2021) |
| "To retrospectively investigate cesarean scar pregnancy (CSP) patients who received systemic methotrexate (MTX) and to clarify the criteria for administering systemic MTX to CSP patients." | ( Eto, E; Hayata, K; Maki, J; Masuyama, H; Mishima, S; Mitsui, T; Ohira, A; Tani, K, 2021) |
| "However, whether more scar tissue removal surgeries could affect the treatment effects of biomaterial implantation still needs to be explored." | ( Cao, Y; Chen, B; Dai, J; Jiang, X; Li, J; Li, X; Liu, W; Meng, L; Ren, C; Shen, H; Tan, J; Wang, L; Wu, S; Xiao, Z; Xue, W; Yin, W; Zhao, M; Zhao, Y; Zhu, H, 2021) |
| "To describe a conservative cesarean scar pregnancy (CSP) treatment in a patient with the desire for future pregnancy." | ( Ambrosio, M; Arena, A; Casadio, P; Salucci, P; Seracchioli, R; Verrelli, L, 2021) |
| "Conservative cesarean scar pregnancy treatment was performed successfully with primary local methotrexate injection followed, after 6 weeks, by hysteroscopic removal of the CSP remnants with the TruClear hysteroscopic tissue removal system." | ( Ambrosio, M; Arena, A; Casadio, P; Salucci, P; Seracchioli, R; Verrelli, L, 2021) |
| "This is the first study to assess scar reduction using CDO adjunct therapy after cervicotomy." | ( Mishra, R; Najafi, B; Pham, A; Suliburk, J; Zulbaran-Rojas, A, 2021) |
| "The total Patient and Observer Scar Assessment Scale (POSAS) score at the 6-month follow-up was significantly lower for the treated site (44." | ( Chen, Z; Gao, Z; Ma, Q; Won, T; Wu, X; Zhang, R, 2022) |
| "We retrospectively evaluated 31 scars of six patients who underwent a single treatment by the Painting CROSS TCA method." | ( Artzi, O; Horovitz, T; Koren, A; Salameh, F; Shehadeh, W, 2022) |
| "Forty-one patients with acne scars were recruited for treatment of boxcar and polymorphic scar with 90% TCA applied with a cosmetic brush." | ( Lim, D; Sun, C, 2022) |
| "Forty-two patients with 67 scars including post-traumatic (43), post-burn (15), post-surgical (5), and post-folliculitis (5) scars treated during 2019-2020 were analyzed." | ( Dinesh, AP; Maninder, K; Richa, R; Suman, P, 2022) |
| "In common, 25 hypertrophic scars were treated in 13 patients; each scar was treated by fractional CO2 laser therapy more than once." | ( Klosová, H; Langová, K; Xinopulos, P; Zálešák, B, 2021) |
| "Accurate scar assessment is crucial in cardiac resynchronization therapy (CRT) candidates, since its presence is a negative predictor for CRT response." | ( Bogaert, J; Claus, P; Degtiarova, G; Duchenne, J; Gheysens, O; Nuyts, J; Schramm, G; Verberne, HJ; Voigt, JU; Vöros, G; Willems, R, 2022) |
| "Acne and acne scars were significantly improved on EGFO-treated sides, while control sides were not." | ( Cho, SI; Choi, S; Kim, DH; Kim, JW; Suh, DH; Yang, JH; Yoon, JY, 2022) |
| "The number of scars and patient and physician satisfaction were the main variables evaluating the effectiveness of the treatment." | ( Behrangi, E; Ghassemi, M; Goodarzi, A; Hosseini-Baharanchi, FS; Shahverdi, MH, 2022) |
| "Post acne scars following sebaceous injury and abnormal wound healing during the course of acne is a prevalent and challenging to treat condition To evaluate microneedling by dermapen with topical vitamin C versus microneedling with topical insulin in treating atrophic post-acne scars." | ( Abbas, MAM; Elgamal, EEAE; Elsaie, ML; Zaky, MS, 2022) |
| "Mechanisms underlying scarring are largely unknown in MMP and effective treatment options are limited." | ( Boch, K; Brinckmann, J; Busch, H; Chakievska, L; Diel, L; Fähnrich, A; Künzel, S; Patzelt, S; Pigors, M; Schmidt, E; Steenbock, H, 2021) |
| "In terms of caesarean scar pregnancies, the treatment was predominantly medical (78." | ( Bouet, PE; Cillard, L; Dabi, Y; Fernandez, H; Lavoué, V; Legendre, G; Nyangoh Timoh, K; Thubert, T, 2022) |
| "As for the popliteal fossa scar, 6 patients underwent further treatment of their hyperpigmented or hypertrophic transverse scar." | ( Hsu, H; Lee, JT, 2022) |
| "The treatment of atrophic acne scars represents a therapeutic challenge." | ( Abdelkader, HA; Allam, RSHM; El-Hadidy, YA; Gawdat, HI, 2022) |
| "On day 22, the scar thickness was the smallest in the combination treatment group (560 ± 42 µm), which was significantly less than in the silver-sulfadiazine cream group (712 ± 38 µm; p < 0." | ( Csenkey, A; Garami, A; Gergics, M; Hargitai, E; Jozsa, G; Kajtar, B; Lorincz, A; Pakai, E; Vajda, P; Vida, L, 2022) |
| "High-resolution scar characterization using late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR) is useful for guiding ventricular arrhythmia (VA) treatment." | ( Akhtar, T; Alugubelli, N; Assis, F; De Vasconcellos, HD; Gasperetti, A; Halperin, H; Kolandaivelu, A; Pandey, P; Shah, R; Sharma, A; Tandri, H; Zhou, S; Zimmerman, SL, 2023) |
| "Patients with scar contracture deformities caused by hand burns were treated with an exoskeleton manipulator system, which was equipped with games to explore its clinical application value." | ( Fan, J; Han, D; Li, X; Xu, J; Xue, Y; Yu, Z; Zhao, D, 2023) |
| "The investigational product, acne scar serum (HEXILAK® Acne Scar Serum) is latest topical formulation developed for treatment of acne scar with unique ingredients, Kollaren and Exo-T." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "The investigational product, acne scar serum (HEXILAK® Acne Scar Serum) is latest topical formulation developed for treatment of acne scar with unique ingredients, Kollaren and Exo-T." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "The investigational product, acne scar serum (HEXILAK® Acne Scar Serum) is latest topical formulation developed for treatment of acne scar with unique ingredients, Kollaren and Exo-T." | ( Aurangabadkar, S; Bhatia, S; Ganjoo, A; Goel, A; Kandhari, S; Patil, CY; Talathi, A, 2023) |
| "We hypothesized that myocardial septal scarring, assessed by cardiac magnetic resonance (CMR) using late gadolinium enhancement (LGE), at the site of cardiac contractility modulation (CCM) lead placement may predict treatment response." | ( Akin, I; Ansari, U; Borggrefe, M; Burkhoff, D; Fastner, C; Kuschyk, J; Liebe, V; Overhoff, D; Papavassiliu, T; Röger, S; Rudic, B; Tülümen, E; Yücel, G, 2022) |
| "We hypothesized that myocardial septal scarring, assessed by cardiac magnetic resonance (CMR) using late gadolinium enhancement (LGE), at the site of cardiac contractility modulation (CCM) lead placement may predict treatment response." | ( Akin, I; Ansari, U; Borggrefe, M; Burkhoff, D; Fastner, C; Kuschyk, J; Liebe, V; Overhoff, D; Papavassiliu, T; Röger, S; Rudic, B; Tülümen, E; Yücel, G, 2022) |
| "When cesarean scar choriocarcinoma is suspected, diagnostic surgery can be chosen for tentative treatment and pathologic sampling." | ( Gao, X; Huang, Y; Li, Y; Wu, M; Zhou, T; Zhu, Q, 2023) |
| "In patients with limited myocardial scar (<6 segments with >75% transmural LGE, n = 354), revascularization had a significantly lower risk of cardiac death than medical treatment alone (aHR 0." | ( Ahn, JM; Choo, SJ; Chung, CH; Jung, SH; Kang, DY; Kang, JW; Kang, SJ; Kim, HJ; Kim, JB; Kim, JJ; Kim, MS; Kim, YH; Koo, HJ; Lee, CW; Lee, JW; Lee, PH; Lee, SE; Lee, SW; Park, DW; Park, H; Park, SJ; Park, SW; Yang, DH, 2023) |
| "Facial scars significantly improved after the first treatment in the delayed-intervention group (p < 0." | ( Chen, R; Liu, Z; Wang, B; Wang, M; Zheng, H, 2022) |
| "When untreated, scarring alopecia develops." | ( Wollina, U, 2023) |
| "Myocardial scar suggestive of possible previous myocarditis was detected in almost one-third of hospital-treated COVID-19 patients." | ( Hästbacka, J; Heliö, T; Holmström, M; Kivistö, S; Paakkanen, R; Syväranta, S; Uusitalo, V; Vaara, SM; Vuorinen, AM; Yar, A, 2023) |
| "Manual scar treatment includes various techniques of therapy." | ( Garncarczyk, A; Lubczyńska, A; Wcisło-Dziadecka, D, 2023) |
| "Therapy included manual scar manipulation, massage, cupping, dry needling, and taping." | ( Garncarczyk, A; Lubczyńska, A; Wcisło-Dziadecka, D, 2023) |
| "The nomogram incorporated the rest scar burden by MPI is highly predictive, and may help to better stratify clinical risk and guide treatment decisions in patients with AHF." | ( Cheang, I; Gao, R; Guo, Q; Li, X; Liao, S; Qu, Q; Sun, J; Yao, W; Zhang, H; Zhou, Y; Zhu, Q; Zhu, X, 2023) |
| "The LVR should be performed to attain scar exclusion in the surgical treatment for IHF, which in turn might protectively affect LV diastolic function and cardiac event-free survival." | ( Cho, Y; Kotani, S; Okada, K; Ozawa, K; Shimizu, H; Shimura, S; Ueda, T, 2023) |
| "Among 12 patients with scar contracture stenosis, 6 (50%) underwent balloon dilation with cryotherapy, 4 (33." | ( Pan, C; Wu, J; Yin, Y; Yuan, S; Zhang, J; Zhang, L, 2023) |
| "Current research on scar treatment is limited and mainly relies on growth factors and drugs to reduce inflammation and scar tissue formation." | ( Chen, X; Kang, J; Yu, W; Yuan, WE; Zhang, W; Zhang, X; Zhang, Y, 2023) |