Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
| Member | Definition | Class |
|---|
| 1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride | A hydrochloride salt that is obtained by reaction of 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide with one equivalent of hydrogen chloride. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo. | 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride |
| 2-methyl-6-(phenylethynyl)pyridine hydrochloride | A hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. | 2-methyl-6-(phenylethynyl)pyridine hydrochloride |
| 6-methyl-2-(phenylethynyl)pyridine | A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. | 2-methyl-6-(phenylethynyl)pyridine |
| adinazolam | A triazolo[4,3-a][1,4]benzodiazepine having a dimethylaminomethyl group at the 1-position, a phenyl group at the 6-position and a chloro substituent at the 8-position. | adinazolam |
| alprazolam | A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug. | alprazolam |
| amperozide | A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs. | amperozide |
| amperozide hydrochloride | The hydrochloride salt of amperozide. | amperozide hydrochloride |
| ANA-12 | A secondary carboxamide that is anthranilic acid in which the carboxy group has undergone condensation with the primary amino group of alpha-amino-epsilon-caprolactam, while the aryl-amino group has undergone condensation with the carboxy group of 1-benzothiophene-2-carboxylic acid. It is a selective, non-competitive antagonist of tropomyosin receptor kinase B (TrkB, also known as tyrosine receptor kinase B). | ANA-12 |
| buspirone | An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position. | buspirone |
| buspirone hydrochloride | A hydrochloride salt resulting from the reaction of equimolar amounts of buspirone and hydrogen chloride. | buspirone hydrochloride |
| chlorazepate | A 1,4-benzodiazepinone in which the oxo group is at position 2, and which is substituted at positions 3, 5, and 7 by carboxy, phenyl and chloro groups, respectively. | clorazepic acid |
| chlormezanone | A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions. | chlormezanone |
| clavulanic acid | Antibiotic isolated from Streptomyces clavuligerus. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. | clavulanic acid |
| clobazam | 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics. | clobazam |
| clonazepam | 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation. | clonazepam |
| clorazepate dipotassium | The compound of monopotassium clorazepate with potassium hydroxide. It is used for the management of anxiety disorders, for the short-term relief of anxiety, as adjunctive therapy in the management of epilepsy, and for the symptomatic relief of acute alcohol withdrawal. | dipotassium clorazepate |
| demethylmirtazapine | A benzazepine metabolite resulting from demethylation of the antidpressant, mirtazapine. | N-demethylmirtazapine |
| diazepam | A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5. | diazepam |
| didesethylflurazepam | A primary amino compound resulting from the dealkylation of both ethyl groups of the anti-insomnia drug flurazepam. It is the major metabolite of flurazepam. | didesethylflurazepam |
| estazolam | A triazolo[4,3-a][1,4]benzodiazepine having a phenyl group at position 6 and a chloro substituent at position 8. A short-acting benzodiazepine with general properties similar to diazepam, it is given by mouth as a hypnotic in the short-term management of insomnia. | estazolam |
| etazolate | A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. | etazolate |
| fludiazepam | | fludiazepam |
| flunitrazepam | A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia. | flunitrazepam |
| flurazepam | A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia. | flurazepam |
| fluvoxamine | An oxime O-ether that is benzene substituted by a (1E)-N-(2-aminoethoxy)-5-methoxypentanimidoyl group at position 1 and a trifluoromethyl group at position 4. It is a selective serotonin reuptake inhibitor that is used for the treatment of obsessive-compulsive disorder. | fluvoxamine |
| glutaurine | A dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals. | glutaurine zwitterion; glutaurine |
| glutaurine | A dipeptide zwitterion that is glutaurine in which a proton has been transferred from the carboxy group to the alpha-amino group. | glutaurine zwitterion; glutaurine |
| hydroxyzine | A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively. | hydroxyzine |
| ly 379268 | An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia. | LY 379268 |
| ly 404039 | An organic heterobicyclic compound that is (1S,5R)-2-thiabicyclo[3.1.0]hexane carrying oxo, oxo, amino, carboxy, and carboxy groups at positions 2, 2, 4S, 4S, and 6S, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 mGluR3 (Ki = 149 nM and 92 nM, respectively) and exhibits antipsychotic and anxiolytic efficacy in animal models. | LY404039 |
| midazolam | An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively. | midazolam |
| midazolam hydrochloride | The hydrochloride salt of midazolam. | midazolam hydrochloride |
| mirtazapine | | mirtazapine |
| nicotine | A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. | (S)-nicotine |
| nordazepam | A 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety. | nordazepam |
| oxazepam | A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5. | oxazepam |
| paroxetine | A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo. | paroxetine |
| paroxetine hydrochloride | The hydrochloride salt of paroxetine. It is an antidepressant drug. | paroxetine hydrochloride |
| paroxetine maleate | A maleate salt obtained by reaction of paroxetine with one equivalent of maleic acid. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo. | paroxetine maleate |
| propranolol | A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3. | propranolol |
| ritanserin | A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action. | ritanserin |
| spinosin | A flavone C-glycoside that is flavone substituted by hydroxy groups at positions 5 and 4', a methoxy group at position 7 and a 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 6 via a C-glycosidic linkage. | spinosin |
| tandospirone | A dicarboximide that is (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione which is substituted by a 4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl group at position 2. It is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM). | tandospirone |
| trazodone | An N-arylpiperazine in which one nitrogen is substituted by a 3-chlorophenyl group, while the other is substituted by a 3-(3-oxo[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl group. | trazodone |
| vortioxetine | An N-arylpiperazine in which the aryl group is specified as 2-[(2,4-dimethylphenyl)sulfanyl]phenyl. Used (as its hydrobromide salt) for treatment of major depressive disorder. | vortioxetine |
| zaleplon | A pyrazolo[1,5-a]pyrimidine having a nitrile group at position 3 and a 3-(N-ethylacetamido)phenyl substituent at the 7-position. | zaleplon |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 22.0612 | 1 | 4 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 23.9341 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 13.6069 | 2 | 3 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 31.8558 | 3 | 7 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 10.7530 | 1 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 17.0385 | 1 | 12 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 30.1272 | 1 | 3 |
| AR protein | Homo sapiens (human) | Potency | 21.4762 | 9 | 58 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 37.5264 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 9.1015 | 1 | 7 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 16.7853 | 4 | 10 |
| Ataxin-2 | Homo sapiens (human) | Potency | 20.9853 | 2 | 11 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 8.4925 | 1 | 6 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 27.3516 | 2 | 9 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 34.0322 | 1 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 16.5545 | 1 | 3 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 6.0114 | 2 | 6 |
| BRCA1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 42.8000 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 16.5927 | 2 | 7 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 18.5700 | 2 | 8 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 26.0381 | 1 | 5 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 13.6681 | 2 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 44.0396 | 2 | 5 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 30.2898 | 2 | 8 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 44.9060 | 1 | 6 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 29.0299 | 2 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 30.2586 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 30.2898 | 2 | 8 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 56.9683 | 2 | 11 |
| CREB-binding protein | Homo sapiens (human) | Potency | 5.4415 | 3 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 5.9978 | 1 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 14.9470 | 1 | 5 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 14.0648 | 1 | 8 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 10.1222 | 1 | 11 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 19.6155 | 1 | 8 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 13.5370 | 2 | 18 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.9274 | 2 | 11 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 17.4186 | 1 | 8 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 7.1525 | 3 | 12 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 22.3072 | 1 | 2 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 21.1923 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 37.1345 | 1 | 4 |
| endonuclease IV | Escherichia coli | Potency | 7.9433 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.7543 | 9 | 62 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 35.2471 | 1 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 21.1303 | 10 | 45 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 28.8562 | 1 | 17 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 17.8511 | 4 | 12 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 22.8643 | 2 | 4 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 35.4813 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 14.0648 | 1 | 8 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 13.5370 | 1 | 9 |
| geminin | Homo sapiens (human) | Potency | 12.9315 | 3 | 19 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 15.9941 | 2 | 23 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 14.2309 | 2 | 7 |
| GLS protein | Homo sapiens (human) | Potency | 14.5784 | 2 | 6 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 19.1167 | 3 | 16 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 25.0786 | 1 | 7 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 18.0636 | 1 | 2 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 32.8851 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 17.2297 | 2 | 23 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 27.5512 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 55.1965 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 14.0648 | 1 | 8 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 2.5458 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 12.5893 | 2 | 6 |
| IDH1 | Homo sapiens (human) | Potency | 15.4329 | 1 | 7 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 14.0648 | 1 | 16 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 19.0919 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 22.9210 | 1 | 4 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 22.9210 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 18.7041 | 3 | 12 |
| interleukin 8 | Homo sapiens (human) | Potency | 47.3079 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 13.4175 | 2 | 11 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 17.0674 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 17.8152 | 3 | 4 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 11.9048 | 1 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 36.4838 | 1 | 6 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 20.2418 | 2 | 5 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 22.3893 | 2 | 6 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 13.1844 | 2 | 12 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 1.7783 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.2269 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 7.5060 | 2 | 4 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 19.3218 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 31.2657 | 1 | 4 |
| Nrf2 | Homo sapiens (human) | Potency | 25.9290 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 20.0669 | 3 | 11 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 25.2060 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 15.0139 | 1 | 3 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 14.8418 | 2 | 8 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 35.7168 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 41.0364 | 3 | 12 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 8.3772 | 1 | 3 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 66.2254 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 2.9093 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 19.0115 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 19.0330 | 1 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 51.4962 | 1 | 6 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 26.4515 | 3 | 13 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 33.4889 | 1 | 1 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 37.9330 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 52.1572 | 1 | 3 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 8.4125 | 1 | 4 |
| polyprotein | Zika virus | Potency | 35.4813 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 21.5098 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 8.2169 | 1 | 7 |
| PPM1D protein | Homo sapiens (human) | Potency | 26.2123 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 26.0836 | 2 | 15 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.7230 | 2 | 8 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0513 | 2 | 5 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 12.3105 | 2 | 8 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 54.3178 | 1 | 6 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 10.8485 | 1 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 32.7693 | 3 | 13 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 15.0087 | 2 | 10 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 19.2482 | 4 | 7 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 27.0105 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 27.0105 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 22.9812 | 1 | 6 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 34.4148 | 1 | 6 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 23.2258 | 1 | 7 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 20.0827 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.8797 | 2 | 40 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 50.1187 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 34.5824 | 3 | 12 |
| Thrombopoietin | Homo sapiens (human) | Potency | 6.7946 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 31.5047 | 2 | 34 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 81.1603 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 27.5112 | 4 | 10 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 14.7263 | 1 | 1 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 8.4125 | 1 | 4 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 8.4125 | 1 | 4 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 40.2321 | 2 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 19.9341 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 14.0737 | 2 | 5 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 61.9285 | 1 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 25.0786 | 1 | 7 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | IC50 | 2.0030 | 2 | 2 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 0.1400 | 10 | 13 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 0.0208 | 36 | 38 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 8.4079 | 14 | 19 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 5.5140 | 3 | 5 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.0787 | 3 | 5 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.1293 | 4 | 8 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 1.0743 | 12 | 14 |
| 5-hydroxytryptamine receptor 2A | Bos taurus (cattle) | Ki | 0.1780 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.4414 | 9 | 12 |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.3561 | 8 | 9 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.8883 | 3 | 7 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.5562 | 9 | 9 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.2543 | 1 | 3 |
| 5-hydroxytryptamine receptor 2B | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 0.6706 | 3 | 4 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 1.2341 | 3 | 6 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.6006 | 10 | 10 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.3240 | 9 | 11 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 0.5376 | 4 | 5 |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | Ki | 30.9807 | 4 | 5 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 1.1925 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.6245 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 4.0384 | 2 | 2 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.7175 | 2 | 2 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 63.2000 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | Ki | 0.1301 | 10 | 10 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.0154 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | IC50 | 11.0000 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | IC50 | 4.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | Ki | 2.7000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Ki | 0.2236 | 7 | 8 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 0.0860 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | Ki | 0.0004 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 0.0860 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 4.0871 | 2 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 11.2004 | 9 | 14 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Ki | 0.0260 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.3136 | 7 | 9 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 13.0593 | 7 | 12 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.3500 | 6 | 8 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.6710 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 13.0593 | 7 | 12 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.3295 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.3500 | 6 | 8 |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | IC50 | 0.0250 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 2.0020 | 3 | 3 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.7500 | 2 | 4 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.1805 | 2 | 2 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 5.6609 | 2 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 0.3064 | 2 | 2 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.7500 | 2 | 4 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.1780 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 5.6609 | 2 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 2.3845 | 3 | 3 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.7500 | 2 | 4 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.1500 | 2 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 5.6609 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | IC50 | 8.0000 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 10.4293 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 8.5445 | 1 | 1 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | Ki | 0.0180 | 1 | 3 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 0.0240 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 150.5600 | 5 | 5 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 41.5000 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 48.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0575 | 5 | 5 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2590 | 3 | 4 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 0.0042 | 4 | 4 |
| Beta-1 adrenergic receptor | Mus musculus (house mouse) | Ki | 0.0024 | 1 | 1 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.2713 | 7 | 7 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0347 | 1 | 1 |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | IC50 | 0.0170 | 1 | 1 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0288 | 1 | 1 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0114 | 6 | 6 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2590 | 3 | 4 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Ki | 0.0014 | 5 | 5 |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 0.0493 | 3 | 3 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2590 | 3 | 4 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 0.0990 | 1 | 1 |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.6000 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Bos taurus (cattle) | IC50 | 1.1533 | 3 | 3 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | IC50 | 4.5600 | 6 | 6 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 118.1000 | 2 | 2 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 500.0075 | 2 | 2 |
| Beta-lactamase | Pseudomonas aeruginosa PAO1 | IC50 | 50.4000 | 2 | 2 |
| Beta-lactamase | Staphylococcus aureus | IC50 | 0.0800 | 1 | 1 |
| Beta-lactamase | Mycobacterium tuberculosis CDC1551 | Ki | 6.3000 | 1 | 1 |
| Beta-lactamase | Acinetobacter baumannii | IC50 | 1,850.0000 | 2 | 2 |
| Beta-lactamase | Acinetobacter pittii | IC50 | 1,208.6733 | 3 | 3 |
| Beta-lactamase | Citrobacter gillenii | IC50 | 0.0090 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 100.0000 | 1 | 1 |
| Beta-lactamase | Escherichia coli | IC50 | 127.1698 | 4 | 4 |
| Beta-lactamase | Klebsiella pneumoniae | IC50 | 0.8700 | 2 | 2 |
| Beta-lactamase | Pseudomonas aeruginosa | IC50 | 0.1000 | 3 | 3 |
| Beta-lactamase | Pseudomonas luteola | IC50 | 0.0360 | 1 | 1 |
| Beta-lactamase | Salmonella enterica subsp. enterica serovar Westhampton | IC50 | 0.0100 | 1 | 1 |
| Beta-lactamase | Serratia fonticola | IC50 | 72.8000 | 1 | 1 |
| Beta-lactamase | Shouchella clausii | IC50 | 0.0850 | 1 | 1 |
| Beta-lactamase OXA-1 | Escherichia coli | IC50 | 3.2000 | 1 | 1 |
| Beta-lactamase SHV-1 | Escherichia coli | IC50 | 0.0280 | 1 | 1 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | IC50 | 0.1700 | 2 | 2 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | Ki | 2.0000 | 1 | 1 |
| Beta-lactamase TEM | Escherichia coli | IC50 | 9.2560 | 5 | 5 |
| Beta-lactamase TEM | Escherichia coli | Ki | 0.8000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 249.0036 | 6 | 25 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 789.9333 | 1 | 3 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | IC50 | 10.5000 | 1 | 1 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | Ki | 11.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | Ki | 12.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | Ki | 12.0000 | 1 | 1 |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | IC50 | 64.0000 | 1 | 1 |
| Cholecystokinin receptor type A | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | IC50 | 94.8571 | 3 | 7 |
| Class D beta-lactamase | Brachyspira pilosicoli | IC50 | 2.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 1,371.3333 | 3 | 3 |
| Cytochrome P450 1A2 | Rattus norvegicus (Norway rat) | Ki | 57.4000 | 1 | 1 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Ki | 72.0000 | 1 | 1 |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | IC50 | 159.9560 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 210.6763 | 2 | 3 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 46.2667 | 3 | 3 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 8.5000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 18.3187 | 5 | 6 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 6.9419 | 4 | 5 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 24.0880 | 6 | 6 |
| D | Bos taurus (cattle) | IC50 | 270.0000 | 1 | 2 |
| D | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 2 | 3 |
| D | Mus musculus (house mouse) | Ki | 1.0000 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | Ki | 4.1670 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 2 | 3 |
| D(2) dopamine receptor | Bos taurus (cattle) | IC50 | 4.0000 | 2 | 3 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 3.2733 | 3 | 3 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1326 | 12 | 14 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.8484 | 10 | 10 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.5490 | 6 | 8 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 1.8935 | 1 | 2 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 2 | 3 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.7572 | 3 | 4 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 5.0000 | 1 | 1 |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 2 | 3 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.0161 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.4400 | 1 | 1 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.1100 | 1 | 1 |
| Diacylglycerol kinase alpha | Homo sapiens (human) | IC50 | 12.8500 | 2 | 2 |
| Endothelin receptor type B | Homo sapiens (human) | Ki | 0.0158 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Ki | 0.0158 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 57.7655 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 0.8975 | 2 | 2 |
| G protein-coupled receptor kinase 5 | Bos taurus (cattle) | IC50 | 150.7250 | 4 | 4 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 0.0097 | 15 | 20 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.4479 | 22 | 25 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.0114 | 13 | 18 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0581 | 17 | 20 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.0140 | 14 | 19 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.0537 | 19 | 22 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 149,848.5767 | 4 | 7 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 0.0078 | 10 | 14 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.0570 | 17 | 20 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 2.6276 | 6 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.7929 | 20 | 23 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 0.0082 | 3 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.6432 | 12 | 22 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.8112 | 32 | 35 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 149,848.5767 | 4 | 7 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 0.1746 | 35 | 43 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.0594 | 16 | 19 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0340 | 23 | 40 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Bos taurus (cattle) | IC50 | 0.0266 | 3 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 149,848.5767 | 4 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Bos taurus (cattle) | Ki | 0.0074 | 7 | 7 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 0.3436 | 46 | 63 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 0.7680 | 34 | 37 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.0347 | 22 | 39 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 0.0652 | 14 | 17 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 174,823.3367 | 3 | 6 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 0.0070 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | Ki | 79.0000 | 1 | 6 |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 18.0000 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 0.3610 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0060 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.0152 | 3 | 3 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Liver carboxylesterase B-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0450 | 1 | 1 |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | IC50 | 29.7400 | 5 | 5 |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | IC50 | 0.0300 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 43.3453 | 2 | 3 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 2 | 2 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 14.6023 | 4 | 7 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Ki | 14.4518 | 3 | 7 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 60.5000 | 1 | 2 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | IC50 | 0.0199 | 20 | 20 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | IC50 | 0.0129 | 6 | 6 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 11.1259 | 8 | 9 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | Ki | 0.0116 | 5 | 5 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Ki | 5.2000 | 1 | 2 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Ki | 100.0000 | 1 | 2 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | Ki | 50.8500 | 1 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.2260 | 2 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.4400 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 46.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 2.5784 | 2 | 2 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 0.0350 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 2.7719 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.1890 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 2.5954 | 2 | 2 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 0.0380 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 0.2440 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.0340 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | Ki | 2.1100 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 1.0597 | 2 | 2 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 0.1230 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 0.0890 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 0.0200 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.0595 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0438 | 27 | 28 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 0.3900 | 4 | 4 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 5.0025 | 4 | 4 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.3763 | 20 | 20 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 0.0841 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.2178 | 37 | 42 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 0.3456 | 10 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | IC50 | 0.0055 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Gallus gallus (chicken) | Ki | 0.0019 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.3444 | 30 | 30 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.0201 | 73 | 87 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 | 14.3000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | IC50 | 0.0087 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Ki | 5.9317 | 17 | 19 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | Ki | 0.2406 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 3.4980 | 17 | 21 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | IC50 | 0.0041 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | IC50 | 0.3256 | 11 | 13 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.3399 | 30 | 30 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | Ki | 0.0024 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.0122 | 77 | 87 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | IC50 | 0.7150 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | IC50 | 5.0025 | 4 | 4 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | Ki | 0.3463 | 22 | 22 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | Ki | 0.0572 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 0.1748 | 54 | 63 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 10.4293 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 8.5445 | 1 | 1 |
| P2X purinoceptor 4 | Homo sapiens (human) | IC50 | 2.8067 | 3 | 3 |
| P2X purinoceptor 4 | Rattus norvegicus (Norway rat) | IC50 | 2.4500 | 2 | 2 |
| Potassium voltage-gated channel subfamily A member 3 | Homo sapiens (human) | IC50 | 31.9000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 149.0822 | 9 | 10 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 8.5445 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 220.0000 | 1 | 1 |
| Protein skinhead-1 | Caenorhabditis elegans | IC50 | 100.0000 | 1 | 1 |
| Quinolone resistance protein NorA | Staphylococcus aureus | IC50 | 7.0000 | 1 | 1 |
| Rhodopsin kinase GRK1 | Bos taurus (cattle) | IC50 | 243.1750 | 4 | 4 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | Ki | 8.4390 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 1.6436 | 3 | 7 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 1.1770 | 3 | 6 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.0360 | 2 | 2 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 20.7500 | 2 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.9058 | 2 | 8 |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | Ki | 0.4600 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 0.4000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.1877 | 3 | 5 |
| Sodium-dependent noradrenaline transporter | Mus musculus (house mouse) | Ki | 0.0200 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.0930 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.0880 | 2 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.0827 | 5 | 7 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 0.3780 | 6 | 7 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.0549 | 12 | 14 |
| Sodium-dependent serotonin transporter | Mus musculus (house mouse) | Ki | 0.0004 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 3 | 4 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Soluble acetylcholine receptor | Aplysia californica (California sea hare) | Ki | 1.0466 | 3 | 3 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 64.3000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 63.2000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 3.7000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 50.5000 | 1 | 1 |
| Sphingosine-1-phosphate lyase 1 | Mus musculus (house mouse) | Ki | 0.0150 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Translocator protein | Homo sapiens (human) | IC50 | 220,906.0800 | 1 | 5 |
| Translocator protein | Bos taurus (cattle) | Ki | 0.0009 | 1 | 2 |
| Translocator protein | Rattus norvegicus (Norway rat) | Ki | 0.3387 | 4 | 6 |
| Transporter | Rattus norvegicus (Norway rat) | IC50 | 0.5190 | 4 | 5 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 2.5999 | 3 | 3 |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 1 | 1 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | Ki | 0.0180 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 75.5000 | 1 | 4 |
| Vasopressin V1a receptor | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 21.0000 | 1 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 18.4667 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 21.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 17.2000 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 17.2000 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 17.2000 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | EC50 | 0.1492 | 10 | 10 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Kd | 13.3792 | 1 | 5 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 0.0556 | 3 | 4 |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Kd | 0.0016 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Kd | 0.0016 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Kd | 0.0016 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | EC50 | 25.3333 | 3 | 3 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | EC50 | 29.0000 | 3 | 3 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | EC50 | 110.0000 | 2 | 2 |
| Acetylcholine receptor subunit epsilon | Homo sapiens (human) | EC50 | 65.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Kd | 0.2931 | 3 | 5 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 401.9732 | 6 | 8 |
| Albumin | Rattus norvegicus (Norway rat) | Kd | 11.5250 | 1 | 2 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0800 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0260 | 2 | 3 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0800 | 1 | 1 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0260 | 2 | 3 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0800 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0260 | 2 | 3 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0148 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 14.4000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Kd | 0.0314 | 7 | 11 |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | Kd | 0.0044 | 2 | 2 |
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0359 | 11 | 11 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0045 | 5 | 7 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Kd | 0.0223 | 9 | 13 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Kd | 0.0514 | 6 | 10 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 2.9800 | 1 | 1 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | Kd | 2.4600 | 1 | 1 |
| Cholecystokinin receptor type A | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Kd | 54.0000 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Kd | 470.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Endothelin-1 receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Envelope glycoprotein | Ebola virus - Mayinga, Zaire, 1976 | Kd | 650.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 0.1027 | 5 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Kd | 0.0202 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | EC50 | 0.5590 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 0.4000 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 0.3517 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Kd | 0.0130 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | EC50 | 0.1191 | 4 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | EC50 | 0.6402 | 6 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | EC50 | 0.3686 | 9 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Kd | 0.1080 | 2 | 2 |
| Glycoprotein IIb | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| Integrin beta | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 0.0079 | 3 | 4 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | EC50 | 0.0154 | 3 | 4 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 21.1000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Kd | 0.0086 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | EC50 | 50.2005 | 2 | 2 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | EC50 | 17.0510 | 2 | 3 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Neuromedin-K receptor | Cavia porcellus (domestic guinea pig) | Kd | 0.0024 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | EC50 | 40.6667 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 21.3260 | 14 | 15 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 3.1424 | 20 | 24 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | EC50 | 10.7398 | 12 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 30.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | EC50 | 0.1270 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | EC50 | 55.2158 | 6 | 6 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | EC50 | 3,948.0836 | 10 | 11 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Kd | 0.0011 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | EC50 | 9.3127 | 23 | 27 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 10.7397 | 12 | 12 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | EC50 | 10.5635 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | EC50 | 13.6576 | 14 | 15 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | EC50 | 33.6667 | 3 | 3 |
| Nuclear receptor subfamily 2 group E member 1 | Homo sapiens (human) | Kd | 0.5000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | EC50 | 14.4000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 14.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 14.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 14.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 14.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 14.4000 | 1 | 1 |
| short transient receptor potential channel 6 isoform 1 | Mus musculus (house mouse) | EC50 | 44.6700 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Kd | 0.4900 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Kd | 0.0400 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Kd | 0.0001 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Kd | 0.0001 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 14.4000 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 14.4000 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 152,369.0000 | 2 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| Translocator protein | Rattus norvegicus (Norway rat) | Kd | 0.2130 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 14.4000 | 1 | 1 |
| Transporter | Rattus norvegicus (Norway rat) | EC50 | 51.0000 | 1 | 1 |
| Type-1 angiotensin II receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |
| Vasopressin V1a receptor | Homo sapiens (human) | EC50 | 5.0119 | 1 | 1 |