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catecholamine
4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
ChEBI ID: 33567
Members (22)
| Member | Definition | Role |
|---|---|---|
| 5-hydroxydopamine | 5-Hydroxydopamine | |
| 6-nitrodopamine | 4-(2-aminoethyl)-5-nitrobenzene-1,2-diol | |
| arbutamine | arbutamine | |
| corbadrine | (-)-alpha-Methylnoradrenaline; alpha-methylnoradrenaline | |
| corbadrine | A catecholamine in which the 2-aminoethyl group is substituted with a hydroxy group at C-1 and a methyl group at C-2, with configurations 1R,2S. A metabolite of alpha-methyl-L-dopa, it is an alpha2-adrenergic agonist and acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry. | (-)-alpha-Methylnoradrenaline; alpha-methylnoradrenaline |
| coryneine | Coryneine | |
| cysteinyldopa | 5-S-cysteinyldopa zwitterion; Cysteinyldopa | |
| deoxyepinephrine | epinine | |
| dobutamine | A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure. | dobutamine |
| dopamine hydrochloride | Dopamine hydrochloride | |
| dopexamine | dopexamine | |
| epinephrine sulfate | Epinephrine sulfate | |
| isoetharine | Isoetharine | |
| L-isoprenaline | An optically active phenylethanolamine compound having an isopropyl substituent attached to the nitrogen atom. | L-isoprenaline |
| metanephrine | Metanephrine | |
| n,n-di-n-propyldopamine | 4-[2-(dipropylamino)ethyl]benzene-1,2-diol | |
| noradrenaline sulfate | Norepinephrine sulfate | |
| nordefrin | Nordephrine | |
| norepinephrine, (+,-)-isomer | A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted. | noradrenaline |
| normetanephrine | Normetanephrine | |
| oxidopamine | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). | oxidopamine |
| racepinephrine | A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen. | 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol |
Research
Studies (17,681)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4,299 (24.31) | 18.7374 |
| 1990's | 4,732 (26.76) | 18.2507 |
| 2000's | 4,358 (24.65) | 29.6817 |
| 2010's | 3,327 (18.82) | 24.3611 |
| 2020's | 965 (5.46) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,163 (6.07%) | 5.53% |
| Reviews | 1,030 (5.38%) | 6.00% |
| Case Studies | 677 (3.54%) | 4.05% |
| Observational | 46 (0.24%) | 0.25% |
| Other | 16,232 (84.77%) | 84.16% |