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cardenolide glycoside

Any member of the class of cardenolides with glycosyl residues attached to position 3.

ChEBI ID: 38092

Members (28)

MemberDefinitionRole
11,15>]Heptadec-14-yl]-5-hydrofuran-2-one, hydrate]Heptadec-14-yl]-5-hydrofuran-2-one,-hydrate.html>11,15>]Heptadec-14-yl]-5-hydrofuran-2-one, hydrate
16-acetylgitoxinA cardenolide glycoside that is the 16-acetate of gitoxin.16-O-acetylgitoxin
acetyldigitoxinA cardenolide glycoside compound consisting of digitoxin having an acetyl substituent at the 3-position on the D-ribo-hexopyranosyl residue at the non-reducing end.3'''-O-acetyldigitoxin
beta-acetyldigoxinacetyldigoxin
CalactinCalactin
calotropinCalotropin
cannogenin thevetosideperuvoside
cerberinA cardenolide glycoside that is the 2'-acetyl derivative of neriifolin.cerberin
convallosideConvalloside
cymarineCymarin
deslanosideA cardenolide glycoside that is lanatoside C with the acetoxy group replaced by a hydroxy group.deslanoside
digitalindigitalin
digitoxinA cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.digitoxin
digoxigenin-bis(digitoxoside)Digoxigenin bisdigitoxoside
digoxigenin-mono(digitoxoside)A steroid saponin that consists of digoxigenin having a digitoxosyl residue attached at position 3.digoxigenin monodigitoxoside
digoxinA cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.digoxin
dihydroouabainA cardenolide glycoside that is ouabain in which the double bond in the lactone ring has been reduced to a single bond. It is a cardiac glycoside and a derivative of ouabain which is used as a sodium pump antagonist and exhibits ionotropic effects.dihydroouabain
evomonosideA cardenolide glycoside consisting of digitoxigenin having an alpha-L-rhamnosyl moiety attached at the O(3)-position.evomonoside
gitaloxinA cardenolide glycoside that is gitoxin in which the 16beta-hydroxy group has been formylated.gitaloxin
gitoxinA cardenolide glycoside that is gitoxigenin in which the 3beta-hydroxy group has been glycosylated with tridigitoxose.gitoxin
helveticosideA cardenolide glycoside that consists of strophanthidin having a digitoxosyl group attached at position 3.helveticoside
k-strophanthin-betak-Strophanthin-beta
medigoxinmetildigoxin
neriifolinA cardenolide glycoside that is digitoxigenin in which the hydroxy goup at position 3 has been converted to its (6-deoxy-3-O-methyl-alpha-L-glucopyranoside derivative. Found in the seeds of Cerbera odollamand in Thevetia ahouia and Thevitia neriifolia.neriifolin
oleandrinA steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.oleandrin
ouabain3-[1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
ouabainA steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.ouabain
strospesideA cardenolide glycoside in which the parent structure gitoxigenin is glycosylated at the 3beta-hydroxy group by beta-D-digitalose.strospeside

Research

Studies (29,974)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199019,588 (65.35)18.7374
1990's4,949 (16.51)18.2507
2000's2,949 (9.84)29.6817
2010's2,034 (6.79)24.3611
2020's454 (1.51)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,171 (3.44%)5.53%
Reviews1,767 (5.18%)6.00%
Case Studies1,478 (4.34%)4.05%
Observational37 (0.11%)0.25%
Other29,630 (86.93%)84.16%