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ChEBI ID: 48346
| Member | Definition | Role |
|---|---|---|
| tadalafil | A pyrazinopyridoindole that is 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione substituted at position 2 by a methyl group and at position 6 by a 1,3-benzodioxol-5-yl group (the 6R,12aR-diastereomer). A phosphodiesterase V inhibitor inhibitor, currently marketed in pill form for treating erectile dysfunction under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension. | tadalafil |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 443 (27.46) | 29.6817 |
| 2010's | 862 (53.44) | 24.3611 |
| 2020's | 308 (19.09) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 392 (22.50%) | 5.53% |
| Reviews | 239 (13.72%) | 6.00% |
| Case Studies | 111 (6.37%) | 4.05% |
| Observational | 18 (1.03%) | 0.25% |
| Other | 982 (56.37%) | 84.16% |