| Excerpt | Reference |
|---|
| "P." | ( Cerimele, D; Serri, F, 1978) |
| "The cause of acne is still obscure, but genetic predisposition, sebaceous overactivity, overgrowth of bacterial flora and exposure to comedogenic substances are all significant factors." | ( Whiting, DA, 1979) |
| "Because acne is androgen dependent, antiandrogen therapy might improve the condition." | ( Abrams, BB; Ellis, CN; Jegasothy, BV; Lookingbill, DP; Lucky, AW; Ortiz-Ferrer, LC; Savin, RC; Shupack, JL; Stiller, MJ; Zone, JJ, 1992) |
| "Infantile cystic acne is rare, and its etiology is not clearly defined." | ( Arbegast, KD; Braddock, SW; Lamberty, LF; Sawka, AR, 1991) |
| "Acne is a skin disorder of the sebaceous follicles that commonly occurs in adolescence and young adulthood." | ( Eichenfield, LF; Leyden, JJ, 1991) |
| "Most women with acne are found to have polycystic ovaries on high resolution pelvic ultrasonography, but most of these women do not manifest the other classical clinical characteristics of the polycystic ovary syndrome." | ( Bunker, CB; Conway, GS; Dowd, PM; Greaves, MW; Jacobs, HS; Newton, JA, 1991) |
| "Acne is known to be one of the features of hyperandrogenism." | ( Brerault, JL; Cathelineau, G; Chivot, M; Fiet, J; Hardy, N; Husson, C; Julien, R; Vexiau, P; Villette, JM, 1990) |
| "Acne is a multifactorial disease." | ( Fiskaadal, HJ; Fyrand, O; Trygstad, O, 1989) |
| "Acne is the result of excessive grease on the skin." | ( Gordon, B, 1985) |
| "Acne is dependent for its development on several factors, one of which is hormonal." | ( Pochi, PE, 1982) |
| "Acne is an ubiquitous problem of adolescence." | ( Tunnessen, WW, 1984) |
| "Comb and brush acne is another external factor to be added to the list of causes of "acne mechanica." | ( Petrozzi, JW, 1980) |
| "Chloracne is an acneiform skin eruption that is still the most sensitive indicator of systemic poisoning caused by chemicals belonging to the group of chlorinated polycyclic aromatic hydrocarbons." | ( Brouwer, A; Coenraads, PJ; Olie, K; Tang, N, 1994) |
| "Acne is one of the most common skin disorders." | ( Balducci, R; Bianchi, P; Colonna, LM; Guglielmi, R; Mangiantini, A; Rossi, FG; Sciarra, F; Toscano, V, 1993) |
| "Acne is a common manifestation of hyperandrogenemia." | ( Rojanasakul, A; Timpatanapong, P, 1997) |
| "Acne is a family of disorders that vary greatly in pathogenesis and clinical manifestation." | ( Kligman, AM, 1997) |
| "Acne is one of the most common diseases in dermatology." | ( Jansen, T; Plewig, G, 1997) |
| "Acne is one of the most common and easily treated diseases of adolescents." | ( Strasburger, VC, 1997) |
| "Though acne is not generally cured, treatment can reduce the severity and frequency of outbreaks, lessen discomfort from inflamed lesions, improve appearance, and prevent or minimize scarring, thereby averting or ameliorating potentially serious adverse psychosocial effects." | ( Quan, MA; Strick, R; Usatine, RP, 1998) |
| "The treatment of acne is based upon simple pathogenic arguments, but needs to be adapted to the type of acne." | ( de Prost, Y; Delanoë, P, 1997) |
| "Amineptine-induced acne is a classical side effect often encountered after prolonged and excessive use of the antidepressor." | ( Amaudric, F; Dandurand, M; Guillot, B; Huet, P; Joujoux, JM, 1996) |
| "Acne is an eminently curable disease." | ( Harms, M; Lübbe, J, 1998) |
| "Steroid acne is a folliculitis that can result from systemic or topical administration of steroid, and has been described as showing a similar clinical picture to Pityrosporum folliculitis, but there have been few reports about the incidence of Pityrosporum ovale and the effect of antimycotic drugs in steroid acne and other acneiform eruptions." | ( Kim, JH; Kim, YS; Lee, SK; Son, SJ; Yang, HY; Yu, HJ, 1998) |
| "Since acne is a multifactorial skin disease, therapies affecting several etiologic factors can have a higher than expected effectiveness." | ( Cerneus, DP; den Brok, JH; Hall, DW; Leuven, PJ; van den Hoven, WE; Wauben-Penris, PJ, 1998) |
| "Acne is the commonest skin disease, and affects 85% of teenage boys and 80% of teenage girls." | ( Simpson, N, 1994) |
| "Acne is not uncommon in the neonatal period." | ( Katoulis, AC; Katsambas, AD; Stavropoulos, P, 1999) |
| "Acne is caused by hormones, androgen, and follicular keratinization, which leads to blocked pores, and P." | ( Cornell, DH, 1999) |
| "Chloracne is caused by exposure to certain halogenated polycyclic hydrocarbons such as polychlorinated dibenzodioxins (PCDDs) and dibenzofurans (PCDFs)." | ( Coenraads, PJ; Olie, K; Tang, NJ, 1999) |
| "Severe pustular acne is a common feature." | ( Condon, CA; Downs, AM; Tan, R, 1999) |
| "Acne is a common problem in adolescents and young adults." | ( Russell, JJ, 2000) |
| "Inflammatory acne is usually treated with topical therapy plus a systemic antibiotic." | ( Johnson, BA; Nunley, JR, 2000) |
| "Radiation-induced acne is a rare, clinically and pathogenetically ill-defined acneiform dermatosis with special features that may occur in irradiated skin areas especially after high doses of deeply penetrating radiation." | ( Goerdt, S; Klemke, CD; Krengel, S; Nestoris, S; Tebbe, B; Wölfer, LU; Zouboulis, CC, 2000) |
| "Propionibacterium acnes is an anaerobic bacillus implicated in certain chronic arthritides." | ( Bourdel, A; Delyle, LG; Duparc, F; Le Loët, X; Michot, C; Vittecoq, O, 2000) |
| "Acne is generally considered to be a disease of adolescence." | ( Holm, EA; Jemec, GB, 2000) |
| "Propionibacterium acnes is the target of antimicrobial treatments for acne vulgaris." | ( Collignon, P; Cove, JH; Cunliffe, WJ; Dréno, B; Eady, EA; Fluhr, J; Leyden, JJ; Oshima, S; Reynaud, A; Ross, JI; Snelling, AM, 2001) |
| "acnes are distributed widely." | ( Collignon, P; Cove, JH; Cunliffe, WJ; Dréno, B; Eady, EA; Fluhr, J; Leyden, JJ; Oshima, S; Reynaud, A; Ross, JI; Snelling, AM, 2001) |
| "Acne is an inflammatory process of follicle sebaceous unites." | ( Iurassich, S; Pace, L; Palagiano, A; Trotta, C, 2001) |
| "Infantile acne is a relatively uncommon condition; there are few data in the literature on the optimum treatment for this disorder." | ( Baron, SE; Coulson, IH; Cunliffe, WJ, 2001) |
| "Hormonal aspects of acne are of particular interest in treating adult women." | ( Thiboutot, D, 2001) |
| "Acne is one of the commonest dermatological problems, experienced by approximately 80% of Western adolescents." | ( Clearihan, L, 2001) |
| "The earlier acne is treated the more likely scarring will be minimised, so a proactive approach is important." | ( Clearihan, L, 2001) |
| "Acne is the most current disease in clinical practice for dermatologist offices, where 15 to 20% of consultation have to deal with." | ( Daniel, F, 2002) |
| "Acne is a chronic disease which evolves under periodic eruptions." | ( Chivot, M, 2002) |
| "acnes is not affected." | ( Akamatsu, H; Horio, T; Tomita, T, 2002) |
| "Nodulocystic acne is a dermatologic disease that can result in significant damage to the skin of the face, chest, and back." | ( Scheman, AJ, 2002) |
| "Acne is a complex, chronic and common skin disorder of pilosebaceous units." | ( Kagoura, M; Makino, T; Morohashi, M; Nakamura, M; Toyoda, M, 2002) |
| "Acne is a multifactorial disease in which androgens appear to play an important role." | ( Hordinsky, M; Leyden, J; Shalita, A; Stanczyk, FZ; Swinyer, L; Weber, ME, 2002) |
| "Acne is a multifactorial disease of the pilosebaceous unit in the skin." | ( Kunynetz, R, 2002) |
| "Acne is a disease that can be seen in the first year of age, early childhood, prepubertal age and puberty." | ( Ando, I; Herane, MI, 2003) |
| "Propionibacterium acnes is a Gram-positive, microaerophilic bacterium that causes skin wounds." | ( Ashkenazi, H; Harth, Y; Malik, Z; Nitzan, Y, 2003) |
| "Acne is a common and disfiguring disease affecting a significant proportion of the general population." | ( Jemec, GB; Larsen, TH, 2003) |
| "Acne is a multifactorial disorder affecting the vast majority of adolescents and young adults." | ( Goffin, V; Piérard, GE; Piérard-Franchimont, C, 2003) |
| "The pathogenesis of acne is complex, with strong evidence supporting the involvement of sebaceous hyperplasia, follicular hyperkeratinisation, bacterial hypercolonisation, as well as immune reactions and inflammation." | ( Gollnick, H, 2003) |
| "Acne is a disease of the pilosebaceous unit, involving abnormalities in sebum production, follicular epithelial desquamation, bacterial proliferation, and inflammation." | ( Leyden, JJ, 2003) |
| "Active acne is considered a contraindication to the use of vitamin-iron-mineral supplements containing cobalt." | ( ERICKSON, JG; McCLEARY, JE; SIDELL, CM, 1958) |
| "Acne is one of the most common dermatological diseases, affecting about 50% of adolescents." | ( Brazzini, B; Cotellessa, C; Ghersetich, I; Manunta, T; Peris, K, 2004) |
| "Propionibacterium acnes is the predominant organism in acne lesions, but the sensitivity of different biotypes of P." | ( Higaki, S; Morohashi, M; Nakamura, M; Yamagishi, T, 2004) |
| "Its usefulness in acne is based on the anti-inflammatory action and was first described with zinc sulfate, then with better tolerated gluconate." | ( Revuz, J; Stéphan, F, 2004) |
| "Propionibacterium acnes is a major inhabitant of adult human skin, where it resides within sebaceous follicles, usually as a harmless commensal although it has been implicated in acne vulgaris formation." | ( Brüggemann, H; Dürre, P; Gottschalk, G; Henne, A; Hoster, F; Hujer, S; Liesegang, H; Strittmatter, A; Wiezer, A, 2004) |
| "acnes is suggested from the results of this study." | ( Bojar, RA; Cunliffe, WJ; Goulden, V; Pollock, B; Stables, GI; Stringer, MR; Turner, D, 2004) |
| "Common acne is steatorrhoeic chronic disease, to which specific is, among others, the presence of blackheads, papulopustular eruptions, purulent cysts and cicatrices." | ( Bergler-Czop, B; Brzezińska-Wcisło, L, 2004) |
| "Acne is a multifactorial disease exhibiting distinct clinical presentations." | ( Cauwenbergh, G; Petit, L; Piérard, GE; Piérard- Franchimont, C; Uhoda, E; Vroome, V, 2004) |
| "Clinical acne is defined by a history of persistent acne (acne present on most days for several years), recent acne treatment, and the presence of 10 or more inflammatory acne lesions and 15 or more comedones." | ( Cappel, M; Mauger, D; Thiboutot, D, 2005) |
| "acnes are involved in the pathogenesis of inflammatory acne." | ( Kikuchi, M; Kitagaki, H; Kitazawa, T; Kuwahara, K; Tsukamoto, T, 2005) |
| "The treatment of acne is based on local and systemic treatments." | ( Dréno, B, 2005) |
| "Acne is a common disorder that may have a considerable psychologic impact including anxiety and depression." | ( D'Arcy, C; Hull, PR, 2005) |
| "Acne is a multifactorial disease characterized by abnormalities in sebum production, follicular epithelial desquamation, bacterial proliferation, and inflammation." | ( Tanghetti, EA, 2005) |
| "The pathogenesis of acne is multifactorial, including hormonal, microbiological and immunological mechanisms." | ( Kim, J, 2005) |
| "Cetuximab-induced acne is frequent, differs from classical acne and may be treated effectively with classical modalities." | ( André, T; Aractingi, S; De Quatrebarbes, J; Molinari, E, 2005) |
| "Acne is an inflammatory condition of the pilosebaceous unit." | ( Iraji, F; Momeni, A; Naji, SM; Siadat, AH, 2006) |
| "acnes is a direct toxic effect rather than as a "true" antibiotic, resistance to benzoyl peroxide does not occur and has never been reported." | ( Weinberg, JM, 2006) |
| "Hirsutism and acne are common and highly distressing complaints in women with polycystic ovary syndrome (PCOS)." | ( Moghetti, P; Toscano, V, 2006) |
| "Acne is a chronic disease hallmarked by sebaceous hyperplasia, follicular hyperkeratosis, and inflammation." | ( Ansorge, S; Bank, U; Faust, J; Gollnick, H; Hartig, R; Helmuth, M; Kähne, T; Lendeckel, U; Neubert, K; Reinhold, D; Thielitz, A; Vetter, R; Wiswedel, I; Wrenger, S; Zouboulis, CC, 2007) |
| "Common acne is the most frequently diagnosed dermatosis at the age of adolescence." | ( Bergler-Czop, B; Brzezińska-Wcisło, L, 2006) |
| "Acne is a chronic inflammatory disease of pilosebaceous units." | ( Ghalamkarpour, F; Nasiri, S, 2006) |
| "Propionibacterium acnes is often discussed as a contributing pathogenic factor in the aetiology of acne lesions." | ( Berger, U; Borelli, C; Jacob, K; Merk, K; Plewig, G; Schaller, M; Vogeser, M; Weindl, G, 2006) |
| "The management of acne is a gratifying experience." | ( Goodman, G, 2006) |
| "Acne is traditionally regarded as a skin disorder of the teenage years." | ( Layton, AM; Williams, C, 2006) |
| "Acne is a disease that affects almost all teenagers (60-90%), and it is the pathology exhibiting the highest morbidity in the 10-24 year-olds age group." | ( Abreu, AM; Amado, JM; Loureiro, L; Massa, A; Matos, ME; Oliveira, J; Verde, A, 2006) |
| "The degrees of acne are higher in schools in the interior." | ( Abreu, AM; Amado, JM; Loureiro, L; Massa, A; Matos, ME; Oliveira, J; Verde, A, 2006) |
| "Acne is very common among teenagers but very few have actually used treatments." | ( Lambert, J; Nijsten, T; Rombouts, S, 2007) |
| "Acne is a multifactorial disorder in which the sebum plays an important pathogenetic role." | ( Bragadin, G; Patrone, P; Pillon, B; Stinco, G; Trotter, D, 2007) |
| "Therefore, acne is not a simple infection with Propionibacterium acnes, but subsequent inflammatory changes are the nature of acne." | ( Murata, K; Tokura, Y, 2007) |
| "Acne is one of the most common concerns of patients with body dysmorphic disorder (BDD), a psychiatric condition defined as a preoccupation with a slight or imagined defect in appearance that causes significant disruption in daily functioning." | ( Bowe, WP; Crerand, CE; Leyden, JJ; Margolis, DJ; Sarwer, DB, 2007) |
| "Acne is an androgen-dependant inflammatory folliculitis with non-inflammatory lesions (open and closed comedos) and inflammatory papules, pustules and sometimes nodules." | ( Faure, M, 2007) |
| "Acne is characterized by different types of lesions at different stages of development." | ( Kircik, L, 2007) |
| "Acne is a typical condition of adolescence and is caused by multi-factorial events including hormonal, microbiological and immunological mechanisms." | ( Choi, JS; Hwang, KW; Jang, SK; Joo, SS; Kim, SG; Lee, DI, 2008) |
| "Acne is generally recognized as a disorder of young adults; however, the referral of patients aged over 25 years with acne is increasing." | ( Alirezaie, NS; Esfahanian, F; Farnaghi, F; Firooz, A; Ghodsi, SZ; Seirafi, H; Vasheghani-Farahani, A, 2007) |
| "Because acne is a complex multifactorial disorder, combination treatment may be required to target its various pathogenic factors." | ( Harper, JC, 2008) |
| "Acne is a complex, chronic and common skin disorder of pilosebaceous units." | ( Jung, HD; Kim, BS; Kim, DW; Lee, HJ; Lee, SJ; Lee, WJ, 2008) |
| "Propionibacterium acnes is a key pathogen involved in the progression of inflammation in acne vulgaris." | ( Gallo, RL; Huang, CM; Huang, CP; Liu, YT; Nakatsuji, T; Zoubouis, CC, 2008) |
| "The effects of acne are profound both physically and psychosocially across all age groups and ethnicities; therefore, prompt recognition and appropriate treatment are critical." | ( Eichenfield, LF; Krakowski, AC; Stendardo, S, 2008) |
| "Acne is treated according to the clinical picture and the pathophysiologically relevant mechanisms, such as seborrhea, follicular hyperkeratosis, P." | ( Degitz, K; Ochsendorf, FR, 2008) |
| "The pathogenesis of acne is multifactorial and complex, but recent advances in molecular genetics have provided additional information on the actions of Proprionibacterium acnes." | ( Barrio, VR; Tom, WL, 2008) |
| "Acne is a prevalent condition in society and often results in secondary damage in the form of scarring." | ( Rivera, AE, 2008) |
| "Propionibacterium acnes is known to play a pivotal role in the pathogenesis of acne vulgaris." | ( Choi, HJ; Chung, MJ; Kang, TW; Kim, HO; Lee, YJ; Park, YM, 2008) |
| "Facial acne is common in adolescents and can have a significant psychosocial impact." | ( Grossman, R; Jorizzo, J; Nighland, M, 2008) |
| "Acne is the most common disease of the skin, yet only a fraction of acne sufferers are treated with prescription products by physicians." | ( Bowe, WP; Shalita, AR, 2008) |
| "Acne is a disorder in which adherence has a major impact on treatment outcome." | ( Beylot, C; Chivot, M; Dréno, B; Faure, M; Pawin, H; Poli, F; Revuz, J, 2009) |
| "Acne is a multifactorial disease characterized by androgenic stimulation of sebaceous glands." | ( Gräser, T; Palombo-Kinne, E; Schellschmidt, I; Schumacher, U, 2009) |
| "Propionibacterium acnes is considered to be involved in the aggravation of acne vulgaris, but it remains unclear whether P." | ( Akimoto, N; Iinuma, K; Ito, A; Kurokawa, I; Nishijima, S; Noguchi, N; Sasatsu, M; Sato, T, 2009) |
| "Propionibacterium acnes is one of the most significant pathogenic factors of acne vulgaris." | ( Akamatsu, H; Akaza, N; Ishii, I; Kishi, M; Matsunaga, K; Mizutani, H; Nakata, S, 2009) |
| "Acne is a widely occurring inflammatory condition that is estimated to affect 40 to 50 million Americans." | ( Abdelhamid, MF; Elsaaiee, LT; Elsaie, ML; Emam, HM, 2009) |
| "acnes is the most sensitive to lauric acid among these bacteria." | ( Fang, JY; Gallo, RL; Huang, CM; Kao, MC; Nakatsuji, T; Zhang, L; Zouboulis, CC, 2009) |
| "The etiology of acne is a complex process, and acne is one of the most common skin disorders affecting millions of people." | ( Lyte, P; Nigam, A; Southall, MD; Sur, R, 2009) |
| "Acne is a common chronic inflammatory dermatosis of the pilosebaceous unit." | ( Caillon, F; Cove, JH; Eady, EA; Jenkins, GR; Layton, AM; Mountford, AP; O'Connell, M, 2010) |
| "Severe scarring acne is frequently treated with isotretinoin." | ( Beer, K; Oakley, H; Waibel, J, 2009) |
| "Acne is the most common disease of the skin." | ( Bowe, WP; Lolis, MS; Shalita, AR, 2009) |
| "Acne is a complex, chronic and common skin disorder of pilosebaceous units." | ( Chi, SG; Jung, HD; Kim, BS; Kim, DW; Kim, JC; Kim, MK; Lee, SJ; Lee, WJ, 2010) |
| "Acne is a very widespread cosmesis problem." | ( Amoh, Y; Baranov, E; Hoffman, RM; Katsuoka, K; Li, L; Tang, L; Yang, M, 2010) |
| "Acne is a common problem for Japanese teenagers and causes personal and social difficulties." | ( Katsuura, J; Kubota, Y; Moriue, T; Nakai, K; Shirahige, Y; Yoneda, K, 2010) |
| "Facial acne is a common disorder and appears to have a considerable impact on quality of life among adolescents." | ( Hanisah, A; Omar, K; Shah, SA, 2009) |
| "Propionibacterium acnes is the common bacterial cause of acne." | ( Ashby, RD; Liu, LS; Solaiman, DK; Zerkowski, JA, 2011) |
| "Acne is frequently found in late adolescence and is associated with social and psychological problems." | ( Bjertness, E; Dalgard, F; Halvorsen, JA; Lien, L; Stern, RS; Thoresen, M, 2011) |
| "Acne is a frequent disease with a strong impact upon quality of life." | ( Wolkenstein, P, 2010) |
| "Acne is a very common skin disease that has major impact on the patients' quality of life." | ( Berg, M; Lindberg, M, 2011) |
| "acnes is still low in Korea, but at this point, there is an increasing trend of MIC." | ( Chang, CL; Kim, MB; Ko, HC; Kwon, KS; Oh, CK; Seo, SH; Song, M, 2011) |
| "Acne is a chronic skin disorder of the pilosebaceous unit; it has a multifactorial pathogenesis." | ( Makrantonaki, E; Tzellos, T; Zampeli, V; Zouboulis, CC, 2011) |
| "acnes is a secretory protein with co-hemolytic activity with sphingomyelinase that can confer cytotoxicity to HaCaT keratinocytes and RAW264." | ( Gallo, RL; Huang, CM; Nakatsuji, T; Tang, DC; Zhang, L, 2011) |
| "Acne is the common skin problem that 85% of the teenagers face today." | ( Ashok Kumar, CK; Avinash Kumar Reddy, G; Mohanalakshmi, S; Rasheed, A, 2011) |
| "Acne is a chronic inflammatory disease of the pilosebaceous follicle." | ( Chaussy, H; Dréno, B; Khammari, A; Knol, AC; Zuliani, T, 2011) |
| "Acne is a characteristic condition of puberty; however, adults who continue to have acne outbreaks frequently attend dermatology clinics." | ( Cornejo, P; Isarría, MJ; Moraga, JM; Muñoz, E; Royo de la Torre, J, 2011) |
| "Acne is a common dermatologic condition that extends into middle age, particularly among women, and is associated with substantial healthcare resource utilization." | ( Boklage, S; Joish, VN; Lin, J; Lynen, R; Schmidt, A, 2011) |
| "Acne is characterized by hyperseborrhea, follicular hyperkeratosis, and growth of propionibacteria." | ( Abels, C; Kaszuba, A; Knie, U; Michalak, I; Werdier, D, 2011) |
| "Prepubertal acne is rare, but important to recognize as diagnostic and therapeutic procedures differ from pubertal acne." | ( Mempel, M; Schnopp, C, 2011) |
| "Propionibacterium acnes is a Gram-positive bacterium that plays an important role in the pathogenesis of acne vulgaris." | ( Brackman, G; Coenye, T; De Witte, E; Honraet, K; Nelis, HJ; Rigole, P; Rossel, B, 2012) |
| "Acne is a skin disease that can be influenced by endocrine abnormalities." | ( Colao, A; Del Prete, M; Di Somma, C; Fabbrocini, G; Faggiano, A; Mauriello, MC; Monfrecola, G, 2012) |
| "Acne is an inflammatory disease of the pilosebaceous follicles." | ( Bagatin, E; Cabral, NC; Picosse, FR; Yarak, S, 2012) |
| "Acne is common in adolescents and especially difficult to manage in people with color." | ( Eichenfield, LF; Krakowski, AC, 2012) |
| "Acne is one of the main reasons for dermatological consultation." | ( Dréno, B; Rougier, A; Seité, S, 2012) |
| "SGH and acne are common during the first months of life and associated with endogenous, physiologically elevated levels of androgens originating from the adrenals and gonads." | ( Dunkel, L; Haanpää, M; Hämäläinen, E; Kuiri-Hänninen, T; Sankilampi, U; Turpeinen, U, 2013) |
| "Propionibacterium acnes is a major contributing factor to the inflammatory component of acne." | ( Christensen, MS; Feng, X; Fernandéz, JR; Gordon, JS; Pérez, E; Rouzard, K; Shroot, B; Stock, JB; Stock, M; Voronkov, M, 2012) |
| "The heritability of acne is almost 80% in first-degree relatives." | ( Bhate, K; Williams, HC, 2013) |
| " Propionibacterium acnes is an important target in acne management." | ( Fich, F; Gárate, C; Garcia, P; Lam, M; Schafer, F; Wozniak, A, 2013) |
| "Acne is a multifactorial chronic dermatosis that can be effectively treated with adjuvant medications." | ( Dhawan, SS; Gwazdauskas, J, 2013) |
| "Propionibacterium acnes is a key pathogen involved in the progression of acne inflammation." | ( Chen, WY; Chuang, LT; Lien, TJ; Liing, YR; Tsai, PJ; Tsai, TH, 2013) |
| "Acne is common among adolescents and can be difficult to manage." | ( Gold, LS, 2013) |
| "Acne is a common disease of the face, chest and back, initially triggered by androgens." | ( Kimball, AB; Lima, XT; Palli, MB; Reyes-Habito, CM, 2013) |
| "acnes is a potent inducer of T helper 17 (Th17) and Th1, but not Th2 responses in human peripheral blood mononuclear cells (PBMCs)." | ( Agak, GW; Elashoff, D; Garbán, HJ; Kim, J; Kim, MH; Krutzik, SR; Nobe, J; Qin, M; Tristan, GR, 2014) |
| "Acne is a chronic inflammatory illness of the pilosebaceous follicle where innate immunity plays a central role." | ( Dréno, B; Jasson, F; Khammari, A; Knol, AC; Nagy, I; Zuliani, T, 2013) |
| "Acne is a common problem that is increasingly being effectively treated with isotretinoin, a highly teratogenic agent." | ( de Vries, LC; Manders, KC; Roumen, FJ, 2013) |
| "Acne is a common disorder affecting the pilosebaceous unit." | ( El-Latif, AA; Elsaie, ML; Elshahed, AR; Hassan, FA; Mohamed, AG, 2014) |
| "Acne is the most common skin disease, with a relative prevalence of 85%-100% among young individuals." | ( Katoulis, A; Katsarou, A; Rallis, E; Verros, C, 2013) |
| "Acne is a common skin disorder that can be problematic for adults as well as for adolescents." | ( Hegel, JK; Sieber, MA, 2014) |
| "Acne is a common condition among adolescents and has the potential to negatively impact on the psychological well-being of those who suffer from it." | ( Daubney, M; Manoharan, S; Oziemski, M; Rowe, C; Ryan, A; Scott, J; Spelman, L; Wilson, P, 2014) |
| "Acne is a common skin condition in adolescents." | ( Ormerod, AD; Yeo, L, 2014) |
| "Acne is the most common skin disease in adolescence, with a prevalence of nearly 100%." | ( Gollnick, HP; Zouboulis, CC, 2014) |
| "Acne is a chronic inflammatory human skin disease, characterized by areas of skin with seborrhoea, comedones, papules, nodules, pimples, and possibly scarring with lesions occurring on face, neck, and back." | ( Garg, T, 2016) |
| "Acne is one of the most common adverse events associated with the use of anticancer agents, such as epidermal growth factor receptor (EGFR) inhibitors." | ( Hong, CK; Kim, BJ; Kim, HK; Kim, MN; Li, K; Yeo, IK, 2014) |
| "Acne is a common skin disorder which can cause physical scaring and impact the quality of life." | ( Apipi, M; Mahat, NF; Muthupalaniappen, L; Puah, JW; Rafee, NM; Sohaimi, AE; Tan, HC, 2014) |
| "Acne is treated according to the clinical observations and pathophysiologically relevant mechanisms, such as hyper-keratinization, seborrhea and bacterial proliferation." | ( DI Meo, N; Errichetti, E; Patrone, P; Piccirillo, F; Stinco, G; Trevisan, G; Valent, F, 2016) |
| "Acne is an important health issue with a major psychological impact in addition to the physical problems it causes." | ( Arzberger, E; Fink-Puches, R; Frühauf, J; Hofmann-Wellenhof, R; Komericki, P; Kopera, D; Kröck, S; Pucher, S; Quehenberger, F, 2015) |
| "Acne is the most common skin disease, affecting up to 95% of adolescents." | ( Bettoli, V; Zouboulis, CC, 2015) |
| "Acne is one of the most frequent skin disorders that occurs in puberty, but often adults also have acne." | ( Kapuścińska, A; Nowak, I, 2015) |
| "Acne is a chronic inflammatory disease for which a long-lasting therapy, very often with topical drugs, is necessary." | ( Barbareschi, M; Brena, M; Veraldi, S, 2015) |
| "Acne is a common and complex skin disease, with a very complex pathogenesis." | ( Colao, A; Del Prete, M; Donnarumma, M; Fabbrocini, G; Faggiano, A; Izzo, R; Marasca, C; Marciello, F; Monfrecola, G; Savastano, R, 2016) |
| "Acne is a chronic inflammatory disease requiring long-term treatment." | ( Friedrich, M; Gollnick, HP; Jäckel, A; Jöstingmeyer, P; Peschen, M; Pettker, R; Pier, A; Porombka, D; Rojo Pulido, I; Streit, V, 2015) |
| "Acne is a chronic disease of the pilosebaceous unit which is most common during adolescence." | ( Gollnick, HP, 2015) |
| "Acne is affecting an increasing number of adult females and so can no longer be considered as a disease of adolescence." | ( Dréno, B, 2015) |
| "Propionibacterium acnes is a key pathogen involved in acne inflammation." | ( Chuang, LT; Chyuan, JH; Huang, CJ; Huang, WC; Li, YY; Tsai, PJ; Tsai, TH, 2015) |
| "acnes are capable to activate NF-κB and p38 MAPK pathways and up-regulate secretion of IL-8 through TLR2-dependent signaling in human SZ95 sebocytes." | ( Hsu, HC; Huang, YC; Li, TT; Yang, CH; Zouboulis, CC, 2015) |
| "Acne is a common skin condition of the pilosebaceous units that affects the young and old, ranges from moderate to severe and can be treated with an array of options." | ( Feldman, SR; Hill, D; Narahari, S; Smith, JA, 2016) |
| "Acne is common in adolescence but is also increasingly seen in adulthood, with about 40% of adults being affected." | ( Dréno, B, 2016) |
| "Acne is one of the most common disorders treated by dermatologists and other health care providers." | ( Alikhan, A; Baldwin, HE; Berson, DS; Bhushan, R; Bowe, WP; Boyer, KM; Dolan, NC; Graber, EM; Harper, JC; Kang, S; Keri, JE; Leyden, JJ; Pathy, AL; Reynolds, RV; Sagan, AA; Schlosser, BJ; Silverberg, NB; Stein Gold, LF; Stern, M; Tollefson, MM; Weiss, JS; Zaenglein, AL, 2016) |
| "Acne is a multifactorial skin disorder frequently observed during adolescence with different grades of severity." | ( Camera, E; Capitanio, B; Goracci, L; Ludovici, M; Picardo, M; Sinagra, JL; Tortorella, S, 2016) |
| "Acne is a multifactorial inflammatory skin disease with high prevalence." | ( Basit, AW; Det-Amornrat, U; Gaisford, S; Goyanes, A; Wang, J, 2016) |
| "Acne is a common, chronic skin disease that has both physical and psychological consequences." | ( Draelos, ZD; Ertel, K; Rom, D, 2016) |
| "Acne is a chronic inflammatory disease whose psychosocial effects can greatly impair quality of life." | ( Dréno, B; Herranz-Pinto, P; López-Estebaranz, JL, 2017) |
| "Acne is a disorder of the pilosebaceous unit, common among adolescents, which may be extended to adulthood." | ( Badiu, C; Călina, D; Docea, AO; Ianoşi, G; Ianoşi, S; Ionescu, O; Neagoe, D; Sifaki, M; Spandidos, DA; Tsatsakis, AM; Tsoukalas, D; Zlatian, O, 2016) |
| "acnes is an emerging issue to be solved." | ( Im, BN; Jeong, S; Kim, MK; Lee, J; Na, K; Park, H; Yang, SG, 2016) |
| "Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production; altered keratinisation; bacterial colonisation of hair follicles on the face, neck, chest and back by Propionibacterium acnes; and an inflammatory response in the skin." | ( Cooper, AJ; Harris, VR, 2017) |
| "Acne is not solely a cosmetic problem." | ( Aygen, E; Ferahbas, A; Kelestimur, F; Sahin, Y; Uludag, SZ; Unluhizarci, K; Uysal, G, 2017) |
| "Acne is a very common and disfiguring disease that affects mostly adolescents and, to some extent, adults." | ( Borowska, K; Brzezinski, P; Chiriac, A; Smigielski, J, 2017) |
| "Acne is the most common skin disorder and can directly affect the patients' self-esteem." | ( Dolder, MA; Thomazini, BF, 2017) |
| "Nodulocystic acne is prone to scarring and difficult to treat with treatments other than oral isotretinoin." | ( Del Pozo Losada, J; Pestoni Porvén, C; Vieira Dos Santos, V, 2017) |
| "Acne is currently considered a chronic rather than an adolescent condition." | ( Gold, MH; Goldberg, DJ; Nestor, MS, 2017) |
| "Acne is usually treated with topical drugs, oral antibiotics, retinoids, and hormonal therapies, but medicinal plants are increasingly employed." | ( Bassino, E; Gasparri, F; Munaron, L, 2018) |
| "Acne is a multifactorial dermatosis, which is influenced not only by hormones but also by the biochemical relationship between them and the pilosebaceous unit." | ( Ha, I; Kim, E; Kim, K, 2017) |
| " Acne vulgaris (acne) is the most common skin disease we see in dermatology practice." | ( Baldwin, HE; Lin, T; Stein Gold, L, 2017) |
| "Propionibacterium acnes is a dominant member of the cutaneous microbiota." | ( Bolla, S; Erdei, L; Kemény, L; Megyeri, K; Orosz, L; Rázga, Z; Seprényi, G; Szabó, K; Urbán, E, 2018) |
| "Acne vulgaris (acne) is the most common skin disease we see in dermatology practice." | ( Baldwin, H; Gold, MH; Lin, T, 2018) |
| "Acne vulgaris (acne) is prevalent in individuals with skin of color, often with more frequent sequelae than in patients with lighter skin color." | ( Alexis, AF; Alvandi, N; Callender, VD; Cook-Bolden, FE; Downie, JB; McMichael, A; Rodriguez, DA; Taylor, SC, 2018) |
| "Acne is a foreseeable adverse effect of testosterone treatment in transgender adolescents, so monitoring for acne is advised." | ( Campos-Muñoz, L; Conde-Taboada, A; López-Bran, E; López-De Lara, D; Rodríguez-Rojo, ML, 2018) |
| "Acne is a common skin disease in adolescence." | ( Li, SS; Lv, T; Nie, S; Wang, HW; Zhang, LL, 2018) |
| "Adult acne is more common in women than in men." | ( Alexis, AF; Harper, JC; Stein Gold, LF; Tan, JKL, 2018) |
| "Acne is one of the most common diseases worldwide and affects ∼50 million individuals in the United States." | ( Barbieri, JS; James, WD; Margolis, DJ; Spaccarelli, N, 2019) |
| "Acne vulgaris (acne) is the most common skin disease in patients who have darker skin with most frequent sequelae of post inflammatory hyperpigmentation (PIH)." | ( Amar, L; Kircik, LH, 2018) |
| "Acne is a chronic inflammatory disease of the skin that occurs when bacteria abnormally grow in hair follicles." | ( Hou, JH; Jang, KH; Koo, B; Lee, KY; Park, CK; Shin, H; Yuk, SH, 2019) |
| "Acne is the most common skin disease, and isotretinoin is the most powerful drug among the various drugs used for its treatment." | ( Akalin, M; Metekoglu, S; Oral, E; Ucar, C, 2019) |
| "Acne vulgaris (acne) is a common skin condition in children and adolescents." | ( Bhatt, V; Eichenfield, LF; Guenin, E; Harris, S; Sugarman, JL, 2019) |
| "Recognition that acne is an inflammatory condition, not an infectious one, has led to a call for reduction in antibiotic use." | ( Baldwin, HE; Marson, JW, 2019) |
| "Recognition that acne is an inflammatory condition, not an infectious one, has led to a call for reduction in antibiotic use, which has culminated in a re-evaluation of our nonantibiotic choices." | ( Baldwin, HE; Marson, JW, 2019) |
| "The pathogenesis of acne is attributed to multiple factors, including altered sebum production, inflammatory processes, dysregulation of the hormone microenvironment, and the proliferation of the skin commensal bacteria, Propionibacterium acnes (P." | ( Agan, FJ; Gerloni, M; Mazzetti, A; Moro, L; Rosette, C, 2019) |
| "Acne is an inflammatory skin disorder in puberty with symptoms including papules, folliculitis, and nodules." | ( Choi, E; Joo, JH; Kim, SS; Lee, EH; Seo, SR; Shin, JH, 2019) |
| "Acne is one of the most common skin problems among human populations." | ( Asawanonda, P; Hashimoto, H; Ikegaki, S; Khamthara, J; Kumtornrut, C; Manabe, SD; Navapongsiri, M; Okutani, Y; Songsantiphap, C; Takagi, Y; Tanaka, N; Wantavornprasert, K, 2020) |
| "Acne is a common, chronic, inflammatory disease of the pilosebaceous unit." | ( Budzisz, E; Erkiert-Polguj, A; Szymańska, A, 2021) |
| "Persistent adult acne is one of the most difficult types of acne to treat." | ( Chlebus, E; Chlebus, M, 2019) |
| "BACKGROUND: Acne is a common problem among Asian adolescents and adults." | ( Armstrong, AW; Desai, SR; Guenin, E; Han, G, 2019) |
| "Acne is primarily an inflammatory disease." | ( Kircik, LH, 2019) |
| "Acne is a common skin disease with important psychosocial impact." | ( Chiodini, P; Donnarumma, M; Fabbrocini, G; Fattore, D; Ferrillo, M; Greco, V; Vastarella, M, 2019) |
| "Acne is a disease unique to humans and is associated with sebaceous glands that are found at high density on the scalp, forehead and face." | ( Shannon, JF, 2020) |
| "Acne is the most prevalent skin disease in the world and antibiotics as its standard treatments have limited and also adverse effects." | ( Aliasl, J; Ghobadi, A; Ghods, R; Hashem-Dabaghian, F; Minaii Zangii, B; Nilforoushzadeh, MA; Shakiba, M; Shakiba, R; Shirbeigi, L, 2021) |
| "Acne is likely less common in adult men because of the declining rate of sebum secretion observed with increasing age, and yet it can be more severe than in adult women." | ( Cook-Bolden, FE; Gold, MH; Guenin, E, 2020) |
| "Acne is a common, economically burdensome condition that can cause psychological harm and, potentially, scarring." | ( Hu, J; Lazic Mosler, E; Li, H; Liu, J; Yang, Z; Zhang, Q; Zhang, Y, 2020) |
| "Acne is a chronic inflammatory disease affecting sebaceous gland follicles." | ( Bertolani, M; Feliciani, C; Lotti, T; Pedrazzi, G; Rodighiero, E; Saleri, R; Satolli, F, 2020) |
| "Acne is a common, multifactorial skin condition, and treatments with novel mechanisms have been elusive." | ( Cartwright, M; Fragasso, E; Gerloni, M; Hebert, A; Mazzetti, A; Stein Gold, L; Thiboutot, D, 2020) |
| "Acne is an inflammatory disorder with a high global burden." | ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020) |
| "Acne is a common adverse event among trans-masculine people using testosterone as masculinizing hormone therapy." | ( Keuroghlian, AS; Singer, S, 2020) |
| "Acne is a common dermatologic condition and significantly affects psychosocial health and quality of life." | ( Biber, JE; Chen, SC; Chren, MM; Edwards, LD; Ferris, LK; Frost, ZE; Hess, R; Hopkins, ZH; Kean, J; Secrest, AM; Taliercio, VL, 2020) |
| "Acne is the eighth most common disease worldwide." | ( Chen, B; Chen, J; Li, J; Li, P, 2020) |
| "Acne is a chronic, inflammatory, and immune mediated disease of pilosebaceous unit, highly prevalent in adolescents." | ( Bagatin, E; Costa, CS, 2020) |
| "Acne vulgaris (acne) is the most common dermatologic disorder seen in black patients." | ( Bhatia, ND; Cook-Bolden, FE; Guenin, E; Werschler, WP, 2020) |
| "Acne is a skin disease common in adolescents and increasingly common in the adult population." | ( Chen, LW; Chen, YJ; Chung, HL; Lee, CJ; Su, JH; Wang, CC, 2020) |
| "Acne is a chronic inflammatory relapsing disease that affect predominantly adolescents, with scarring as a frequent sequele." | ( Balduzzi, V; Bernardini, N; Maddalena, P; Mambrin, A; Marchesiello, A; Michelini, S; Potenza, C; Proietti, I; Skroza, N; Tolino, E; Volpe, S, 2020) |
| "Acne is one of the cutaneous manifestations of polycystic ovary syndrome (PCOS)." | ( Chang, YT; Huang, YC; Yee, FJ; Yen, H, 2021) |
| "Acne is a common inflammatory skin disease with the dysregulation of innate and adaptive immunity." | ( Deng, Z; Li, J; Xin, Y; Zeng, D; Zhang, S; Zhang, Y, 2020) |
| "Acne is a widespread disorder of the pilosebaceous unit." | ( Farag, A; Hegazy, R; Ibrahim, SM; Kamel, MM; Mongy, M; Shalaby, S, 2021) |
| "Acne is an inflammatory skin disease of the pilosebaceous unit, involving four essential factors: hyperseborrhoea combined to a modification of sebum composition, colonization by Cutibacterium (C." | ( Aymard, E; Closs, B; Grimaldi, C; Jugé, R; Laclaverie, M; Marchand, L; Rouaud-Tinguely, P, 2021) |
| "Acne is one of the common dermatological skin inflammatory conditions." | ( Alvi, SB; B, V; Jogdand, A; John, R; Rajalakshmi, PS; Rengan, AK; Sanjay, AY, 2021) |
| "Acne is one of the skin diseases that include abnormalities in the production of sebum, changes in the microbial flora, abnormal keratinization, and inflammation." | ( Emam, M; Mohammad Soleymani, S; Salimi, A, 2021) |
| "Acne is a chronic disease that affects the pilosebaceous follicle and is characterized by the presence of non-inflammatory and/or inflammatory lesions, affecting both adolescents and adults." | ( Campos, V; Correia, P; Gonçalves Júnior, JE; Kalil, C; Pitassi, L; Sant'Anna, B, 2021) |
| "Acne is a common skin disease that occurs in pilosebaceous units and is often prevalent in adolescence." | ( Jeong, JY; Kim, HJ; Kim, KE; Lee, SJ; Park, JH; Park, TJ; Ryu, HJ; Suh, DH, 2021) |
| "Acne is very common and can have a substantial impact on wellbeing." | ( Bucher, HC; Finlay, AY; Layton, AM; Little, P; Maund, E; Newell, D; Regas, C; Santer, M; Sivaramakrishnan, G; Soulsby, I; Sridharan, K; Stuart, B; Tang, KF; Wilcox, C, 2021) |
| "Acne is a serious skin problem that affects mostly adolescents." | ( AlMatar, M; Mahmood, MH; Makky, EA; Qi, TBG; Wen, KX, 2022) |
| "Acne is one of the most common skin diseases in the adolescent period." | ( Karadag, AS; Kaya Ozden, H, 2021) |
| "Patients with acne are increasingly using sunbeds as a self treatment despite the harmful effects." | ( Bali, R; Felton, SJ; Ji-Xu, A, 2022) |
| "Acne is one of the most common inflammatory skin diseases worldwide and can have significant psychosocial impact and cause permanent scarring." | ( Chinnery, F; Day, L; Eminton, Z; Francis, N; Griffiths, G; Layton, AM; Little, P; Muller, I; Nuttall, J; Renz, S; Ridd, MJ; Sach, T; Santer, M; Soulsby, I; Stanton, L; Stuart, B; Thomas, K; Thomas, KS, 2021) |
| "Acne is a chronic inflammatory skin disease which involves the pilosebaceous unit." | ( Goldust, M; Gupta, A; Mohammadnezhad, F; Rokni, GR; Saeedi, M; Sandhu, S; Shadi, S; Sharma, A, 2021) |
| "Acne is one of the most common dermatological skin problem caused due to inflammation of the skin, leading to unfavorable growth of Propionibacterium acnes." | ( Bhagyawant, SS; Chaudhary, M; Srivastava, N, 2022) |
| "Acne is a common skin disorder that involves an infection inside the hair follicle, which is usually treated with antibiotics, resulting in unbalanced skin microbiota and microbial resistance." | ( Badia, J; Baldoma, L; Calpena, AC; Díaz-Garrido, N; Espina, M; Folle, C; García, ML; Marqués, AM; Sánchez-López, E, 2021) |
| "Acne is one of the most common adverse effects for many transmasculine patients receiving testosterone." | ( Acosta, JP; Barron, J; Gold, S; Radi, R; Yeung, H, 2022) |
| "Acne is a chronic inflammatory skin disease with high incidence and recurrence." | ( Ariyawati, A; Chen, J; Chen, Y; Li, Y; Liu, L; Pu, Y; Shao, X; Wang, J; Zhang, L; Zhang, Y, 2022) |
| "The pathogenesis of acne is multifactorial and involves inflammation, bacterial dysbiosis, and androgen stimulation." | ( Burma, NE; Parsons, L; Woo, TE, 2022) |
| "Acne is one of the most common dermatological disorders." | ( Lake, E; Nickles, MA, 2022) |
| "Cutibacterium acnes is the main pathogen in periprosthetic shoulder infections." | ( Bouaicha, S; Catanzaro, S; Uçkay, I; Unterfrauner, I; Wieser, K, 2022) |
| "Acne is a common chronic inflammatory skin disorder that affects the pilosebaceous unit and has a multifactorial etiology, including bacterial colonization of the hair follicle." | ( García, B; Martín, C; Merayo, J; Ordiales, H; Pevida, M; Quirós, LM; Rodríguez, D; Vázquez, F, 2022) |
| "Acne is a chronic inflammatory disease that occurs in the sebaceous glands of the hair follicles." | ( Chen, J; Chen, X; Liao, G; Lin, L, 2022) |
| "Acne is a chronic, inflammatory skin disorder of pilosebaceous units." | ( Chaichalotornkul, S; Charoenwattanayothin, A; Saiwichai, T, 2022) |
| "Acne is an off-label use of some COCs." | ( Brady, PH; Gin, GT; Rosenblum, E; Wilkinson, LD, 2022) |
| "Acne is the most frequent adverse event associated with upadacitinib treatment in patients with moderate-to-severe atopic dermatitis." | ( Barbarot, S; Guttman-Yassky, E; Jiang, P; Ladizinski, B; Liu, J; Mendes-Bastos, P; Prajapati, VH; Simpson, EL; Teixeira, HD; Vigna, N, 2022) |
| "Although truncal acne is thought to have the same pathophysiology as facial acne, treatment response may differ based on body area involvement." | ( Kircik, L, 2022) |
| "Acne is one of the most common and widespread skin conditions, affecting the health as much as patients' quality of life." | ( Annunziata, MC; Di Vico, F; Fabbrocini, G; Genco, L; Nastro, F; Villani, A, 2022) |
| "Acne is the most common chronic inflammatory disease of hair follicles and sebaceous glands in dermatology." | ( Guo, R; He, X; Xu, K; Xuan, W, 2022) |
| "Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from different cofactors." | ( Annunziata, MC; Cacciapuoti, S; Fabbrocini, G; Marasca, C; Ruggiero, A, 2022) |
| "Acne is a chronic inflammatory disease of the sebaceous gland attached to the hair follicles." | ( Hwang, HJ; Kim, JE; Lee, KW, 2022) |
| "Acne is a chronic inflammatory disease of the sebaceous gland attached to the hair follicles." | ( Hwang, HJ; Kim, JE; Lee, KW, 2022) |
| "Acne is a chronic inflammatory disease of the sebaceous gland attached to the hair follicles." | ( Hwang, HJ; Kim, JE; Lee, KW, 2022) |
| "Acne is the eighth-most prevalent inflammatory skin disease with no optimal treatment." | ( Chen, Y; Guo, Y; Jiao, X; Liu, R; Lu, T; Ruan, Z; Xie, Q; Yu, H; Yuan, M; Yuan, Y; Zeng, M, 2023) |
| "Acne is a very common condition." | ( Andrade, LSM; Bacquey, A; Bagatin, E; Baradat, S; Lauze, C; Mengeaud, V; Miot, HA; Rocha, MA; Soares, JLM; Thouvenin, MD, 2023) |
| "Acne is a multifactorial inflammatory disease of the pilosebaceous unit in which Cutibacterium acnes is one of the main triggers." | ( Bessou-Touya, S; Chansard, N; Duplan, H; Galliano, MF; Garidou, L; Maitre, M; Mengeaud, V; Mias, C, 2023) |
| "Acne is a multifactorial chronic inflammatory disease of the pilosebaceous unit, where Cutibacterium acnes plays a main role." | ( Alvarez, S; Bessou-Touya, S; Bouyer, K; Dalmon, S; Duplan, H; Gravier, E; Mengeaud, V; Mias, C; Ribet, V; Thouvenin, MD, 2023) |
| "acnes is increasing in patients with acne vulgaris attributable to acquisition of exogenous genes in specific strains." | ( Asai, T; Hayashi, N; Horiuchi, Y; Koizumi, J; Koyanagi, S; Nakaminami, H; Nakase, K; Nakazaki, E; Watanabe, K; Yamazaki, A, 2023) |
| "Acne is an inflammatory disease of the pilo-sebaceous unit, which mainly affects young adolescents." | ( Chello, C; Conforti, C; Dianzani, C, 2021) |
| "Acne is a prevalent chronic inflammatory disease that can cause severe psychiatric effects and physical scarring of the skin." | ( Armstrong, AW; Kircik, L; Peterson, H, 2023) |
| "Acne is a common inflammatory condition that mostly involves the face, chest and back." | ( Elsaie, ML; Hawwas, ARM; Mohamed, HAK; Sayedahmed, OME, 2023) |
| "Acne is a dermatologic disease with a strong pathologic association with human commensal Cutibacterium acnes." | ( Caldera, JR; Chatterjee, A; Choudhury, B; Desmond, T; Du, X; Gonzalez, C; Hajam, IA; Katiki, M; Kolar, S; Lázaro-Díez, M; Li, H; Liu, GY; McNally, R; Murali, R; Paulchakrabarti, M; Tsai, CM, 2023) |
| Excerpt | Reference |
|---|
| "After 12 weeks of treatment, the mean acne score had decreased from 100% to 15%." | ( Juhlin, L; Michaëlsson, G; Vahlquist, A, 1977) |
| "11-1430 in the treatment of acne vulgaris, especially when used in the tropics." | ( Handojo, I, 1977) |
| "Surface glycerol in untreated acne subjects was significantly less than that expected theoretically, whereas the amounts of such glycerol in treated acne patients and in control subjects closely approached the theoretically expected values." | ( Hawk, JL; Rebillo, T, 1978) |
| "To date, there is no single treatment for acne." | ( Hurwitz, S, 1979) |
| "The recent interest in treating acne with one of the retinoid drugs has been accompanied by a wide variety of ocular side effects involving the eyelids, cornea, lens, optic nerve and retina." | ( Lerman, S, 1992) |
| "Twenty-five previously untreated acne patients were monitored throughout a 6-month course of therapy with either tetracycline or minocycline for changes in the numbers of staphylococci, propionibacteria and yeasts of the genus Malessezia on the skin surface." | ( Cove, JH; Cunliffe, WJ; Eady, EA; Holland, KT, 1990) |
| "Azelaic acid is effective in the treatment of acne because it possesses an activity against all of these factors." | ( De Luca, C; Nazzaro-Porro, M; Passi, S; Picardo, M, 1989) |
| "All subjects were young women being treated for acne." | ( Lander, CM, 1989) |
| "Both treatments reduced acne lesion counts." | ( Coryell, GM; Goltz, RW; Neidert, GL; Schnieders, JR, 1985) |
| "Regarding treatment of acne vulgaris and rosacea, there is not much difference between hospital and practice nor among practicing dermatologists." | ( Böcker, KH, 1986) |
| "The successful treatment of acne depends essentially on the degreasing of the skin to an extent which produces peeling, which is the observable index of adequate treatment." | ( Gordon, B, 1985) |
| "Spironolactone is used to treat hirsutism and acne because of its antiandrogenic effects, brought about through suppression of gonadal androgen production by blocking cytochrome P450 and by competitive inhibition of dihydrotestosterone at the skin androgen receptor." | ( Cunliffe, WJ; Hughes, BR, 1988) |
| "Today the treatment of acne vulgaris offers a broad spectrum of topic and systemic therapeutics." | ( Worret, WI, 1988) |
| "Isotretinoin, a drug used for the treatment of acne, has been shown to have teratogenic effects." | ( Hansen, LA; Pearl, GS, 1985) |
| "The use of several modalities for the treatment of acne scarring is advocated; these include dermabrasion, punch-transplant replacement techniques, and collagen implants." | ( Stegman, SJ; Tromovitch, TA, 1982) |
| "Successful treatment of acne conglobata with 13-cis-retinoic acid (isotretinoin, Ro 4-3780) has already been reported in this journal [25, 36]." | ( Cörlin, R; Maas, B; Mack-Hennes, A, 1984) |
| "With zinc treatment acne improved with about one third as rated with a score system." | ( Göransson, K; Lidén, S; Odsell, L, 1980) |
| "Few studies of topical treatment in acne stand up to modern scientific requirements, and several of those which do suggest that some modalities make acne worse rather than better." | ( Hjorth, N, 1980) |
| "The effect of 13-cis-RA treatment on severe acne is consistent with the dramatic decrease in androgen 5 alpha-reduction observed mainly in the skin." | ( Belanger, A; Boudou, P; Chivot, M; Fiet, J; Julien, R; Soliman, H; Vexiau, P; Villette, JM, 1994) |
| "The edema was resistant to conventional treatment of acne including various systemic and topical antibiotics, isotretinoin and interferon-gamma." | ( Jansen, T; Jungfer, B; Plewig, G; Przybilla, B, 1993) |
| "The recommended dose of minocycline for treating acne, especially in male patients, should be re-assessed." | ( Cove, JH; Cunliffe, WJ; Eady, EA; Gardner, KJ; Jones, CE; Taylor, JP, 1993) |
| "During treatment, acne improved in most patients, reaching at cycle 9 a low score (absent or minimal) in 62% of the cases in the GTD group (mean acne score = 1." | ( Mango, D; Manna, P; Miggiano, GA; Ricci, S; Serra, GB, 1996) |
| "Minocycline was given for treatment of cystic acne and hidradenitis suppurativa as well as pyoderma gangrenosum." | ( Shenefelt, PD, 1996) |
| "The topical treatment of acne with adapalene gels was found to be safe and effective, with a dose-related response." | ( Alirezai, M; Czernielewski, J; Jablonska, S; Meynadier, J; Verschoore, M, 1996) |
| "Significant cost savings when treating acne patients with oral isotretinoin as compared to other treatment modalities were further proven in this study." | ( Caputo, R; Cavicchini, S; Cooper, A; Cunliffe, WJ; Fyrand, OL; Gollnick, H; Layton, AM; Leyden, JJ; Mascaró, JM; Ortonne, JP; Shalita, A; van de Kerkhof, PC, 1997) |
| "Twelve months after treatment, acne grades and inflamed lesion counts remained significantly improved (P < 0." | ( Clark, SM; Cunliffe, WJ; Goulden, V; McGeown, C, 1997) |
| "Isotretinoin, used to treat severe acne, has been shown to induce hormonal changes, especially to reduce 5 alpha-reductase in the production of the tissue-derived dihydrotestosterone (DHT) metabolite 3 alpha-Adiol G." | ( Oikarinen, A; Palatsi, R; Ruokonen, A, 1997) |
| "The costs and benefits of alternative treatments for acne should be assessed over a period of at least 2 years, preferably longer." | ( Newton, JN, 1997) |
| "Isotretinoin has revolutionized the treatment of severe acne unresponsive to oral antibiotics." | ( Lear, JT; Smith, AG; Tan, BB, 1997) |
| "In the treatment of acne, topical clindamycin/benzoyl peroxide combination gel is well tolerated and superior to either individual ingredient." | ( Chalker, DK; Huerter, CJ; Katz, HI; Kempers, SE; Klauda, HC; Lindholm, JS; Lookingbill, DP; Schelling, DJ; Swinehart, JM, 1997) |
| "Topical tretinoin is effective treatment for both acne and photoaging." | ( Feldman, SR; Fleischer, AB; McConnell, RC; Williford, PM, 1998) |
| "Tretinoin treatment of acne and of nonacne conditions were equal at an age of 44." | ( Feldman, SR; Fleischer, AB; McConnell, RC; Williford, PM, 1998) |
| "Antibiotics used for the treatment of acne significantly inhibited ROS generated by neutrophils, when compared to other antibiotics." | ( Akamatsu, H; Horio, T, 1998) |
| "It is indicated for treatment of acne vulgaris, alone or with other antiacneic topicals." | ( Bonardeaux, C; de la Brassinne, M, 1998) |
| "Pediatricians who use this drug for treatment of acne should be aware of this serious potential relation and stop the drug immediately when suspicion is raised." | ( Bousvaros, A; Cohen, M; Jonas, MM; Perez-Atayde, AR; Teitelbaum, JE, 1998) |
| "All were being treated for acne vulgaris." | ( Buncic, JR; Quinn, AG; Singer, SB, 1999) |
| "We conclude that the preferred treatment of acne fulminans is oral prednisolone 0." | ( Cunliffe, WJ; Seukeran, DC, 1999) |
| "EE/CPA is an effective treatment for acne of all grades and all types of lesion." | ( Albring, M; Brill, K; Gollnick, H, 1999) |
| "Both treatments improved acne and were well tolerated." | ( Ballagh, SA; Bradshaw, KD; Nichols, M; Stanczyk, FZ; Thorneycroft, IH; Weber, ME, 1999) |
| "Effective treatment of acne vulgaris can prevent emotional and physical scarring." | ( Johnson, BA; Nunley, JR, 2000) |
| "PDT was beneficial in the treatment of acne." | ( Ishibashi, A; Itoh, Y; Ninomiya, Y; Tajima, S, 2001) |
| "Isotretinoin treatment for acne can lead to inflammatory flare-ups or an aggravation, occasionally leading to acne fulminans." | ( Chivot, M, 2001) |
| "This is suitable for treating deeper acne scars, and may be combined with other procedures, e." | ( Weinstein, C, 1999) |
| "Minocycline is widely used in the treatment of acne and increasingly in the treatment of rheumatic diseases." | ( Gordon, MM; Porter, D, 2001) |
| "The effectiveness of treatment for acne vulgaris cannot be determined due to the small sample populations involved in the trials." | ( Farquhar, C; Jepson, R; Lee, O; Toomath, R, 2001) |
| "Topical retinoids are a mainstay in the treatment of acne vulgaris." | ( Wolf, JE, 2001) |
| "During the first 4 weeks before treatment, acne lesions were evaluated on a 3-times weekly basis to establish a pattern of progression and determine the length of time to resolution." | ( Kligman, AM; Pagnoni, PA; Poncet, M; Rizova, E; Stoudemayer, T, 2001) |
| "The drug is an effective treatment for acne that is refractory to other therapies, but it is a teratogen and can cause serious side effects." | ( Swann, J; Vega, A; Wysowski, DK, 2002) |
| "In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids." | ( Guenther, LC, 2002) |
| "Multiple modalities are available for treating acne scars, one of which is chemical peeling." | ( Al-Sharqi, AI; Al-Waiz, MM, 2002) |
| "The topical treatment of acne has a great place in the therapeutic range of products which is available." | ( Auffret, N, 2002) |
| "Subjective evaluation of the effect of treatment on facial acne by dermatologists, gynecologists, and the subjects themselves indicated an excellent or good improvement for most subjects in both groups." | ( Gerlinger, C; Heithecker, R; van Haselen, CW; van Vloten, WA; van Zuuren, EJ, 2002) |
| "Isotretinoin has been used to treat acne since 1982." | ( Alcalay, J; Landau, M; Zucker, A, 2001) |
| "Topical retinoids are highly effective treatments for acne vulgaris." | ( Berger, RS; Grossman, RM; Jorizzo, JL; Kim, YH; Martin, AG; Nighland, M; Nyirady, J; Pandya, AG; Schulz, KK; Strauss, JS, 2001) |
| "SH therapy is indicated for treatment of female acne (reports of 70% success after 2-6 months' intensive therapy), and in some cases male acne, and also for seborrhoea (report of 90% success after 1-3 months' intensive treatment), also for female sebocystamatose and Fox-Fordyce disease." | ( Zaun, H, 1976) |
| "Effective medications to treat acne sometimes become unavailable in certain countries, either for economic reasons or for shortage of them in the pharmaceutical market." | ( Kaminsky, A, 2003) |
| "This article reviews the treatment of acne in adolescents." | ( Goulden, V, 2003) |
| "Rare are reports about isoretinoin treatment for acne in dialysis or kidney transplant patients whereas its efficacy and safety make it very interesting." | ( Bressieux, JM; Montagnac, R; Reguiaï, Z; Schillinger, F, 2003) |
| "Minocycline is an effective treatment of acne vulgaris, especially for inflammatory forms." | ( Bamberg, C; Gross, G; Laskowski, J; Zimmermann, R, 2003) |
| "The successful treatment of acne pits of the face by planing in patients having keloids elsewhere on the body is reported." | ( AYRES, S; LUIKART, R; WILSON, JW, 1958) |
| "We sought to determine if treatment of severe acne with oral isotretinoin varied with patient sex, race, or both." | ( Feldman, SR; Fleischer, AB; McMichael, A; Simpson, JK, 2003) |
| "The effectiveness of treatment for acne vulgaris cannot be determined due to the small sample populations involved in the trials." | ( Farquhar, C; Jepson, R; Lee, O; Toomath, R, 2003) |
| "Since our patches for the treatment of acne was aimed to localize TS into skins, TC content of 5 wt." | ( Hwang, SJ; Kim, JC; Lee, TW, 2003) |
| "He was being given isotretinoin to treat acne conglobata." | ( Janzing, JG; van Broekhoven, F; Verkes, RJ, 2003) |
| "Topical tretinoin is used in the treatment of acne and other dermatoses." | ( Ioannides, D; Lefaki, I; Minas, A; Teknetzis, A; Vakali, G, 2004) |
| "At the end of the eighth treatment, acne clearance for the non-inflammatory and inflammatory lesions was 63 +/- 21% and 50 +/- 32%, respectively." | ( Elman, M; Lask, G, 2004) |
| "Typical efficacy expected in the treatment of acne was observed." | ( Bryce, GF; Chalker, DK; Chin, C; DiGiovanna, JJ; Eberhardt, DR; Eichenfield, L; Hebert, AA; Jarratt, M; Jones, T; Kang, S; Kempers, S; Khoo, KC; Langman, CB; Ling, M; Lowe, NJ; McLane, JA; Menter, A; Newhouse, J; Ondovik, M; Pak, J; Pariser, D; Rafal, ES; Rich, P; Rodriguez, D; Savin, RP; Shah, LP; Smith, SR; Sullivan, S; Tschen, EH; Wu, E, 2004) |
| "While isotretinoin, used to treat acne vulgaris, has not been demonstrated to be associated with depression or suicide, the possibility of a relatively rare idiosyncratic adverse effect remains." | ( Magin, P; Pond, D; Smith, W, 2005) |
| "Isotretinoin (RA), used for the treatment of cystic acne, is a powerful teratogen, causing craniofacial dysmorphisms and neural tube defects." | ( Descartes, M; Elsas, FJ; Morrison, DG, 2005) |
| "On the contrary, treatment of acne either with conservative therapy or with isotretinoin was associated with a decrease in depressive symptoms." | ( Allen, A; Chia, CY; Chibnall, J; Lane, W; Siegfried, E, 2005) |
| "It is well known that many treatments of acne are photosensitizing." | ( Duteil, L; Ortonne, JP; Queille-Roussel, C, 2005) |
| "Systemic isotretinoin has been used to treat severe acne vulgaris for 20 years." | ( Akyol, M; Ozçelik, S, 2005) |
| "The bastion of treatment for acne vulgaris has been the use of topical and systemic therapies." | ( Baugh, WP; Kucaba, WD, 2005) |
| "We previously reported that treatment of acne with 13-cis-retinoic acid causes insulin resistance and disturbances in lipid metabolism resembling those of the insulin-resistance syndrome." | ( Ebeling, P; Koistinen, HA; Koivisto, VA; Remitz, A, 2006) |
| "It is a cost-effective treatment for acne grade I-II." | ( Fluhr, JW; Worret, WI, 2006) |
| "For the treatment of acne, isotretinoin is dosed at 0." | ( Bangalore, S; Scheinfeld, N, 2006) |
| "As zinc/clindamycin gel is a topical treatment for acne, the lower systemic bioavailability may be beneficial because there may be a correspondingly lower risk of systemic events in zinc/clindamycin gel-treated subjects." | ( Chassard, D; Evene, E; Kanis, R; Namour, F; Ntssikoussalabongui, B; Schmitz, V, 2006) |
| "acnes in vivo in untreated acne patients and during standard acne regimens." | ( Berger, U; Borelli, C; Jacob, K; Merk, K; Plewig, G; Schaller, M; Vogeser, M; Weindl, G, 2006) |
| "Successful treatment of acne requires knowledge of the performance capabilities of available treatments and patient expectations." | ( Campbell, JL; Weiss, JS, 2006) |
| "Effective treatment of acne often involves combination therapy." | ( Gold, LS, 2006) |
| "Adherence is necessary for successful treatment of acne, and patient satisfaction is crucial for adherence." | ( Cook-Bolden, F, 2006) |
| "Effective treatment of facial acne scarring presents a major challenge." | ( Lipper, GM; Perez, M, 2006) |
| "Isotretinoin is an effective and safe treatment for acne in Iranian patients." | ( Ghaffarpour, G; Mazloomi, S; Seyed, KS; Soltani-Arabshahi, R, 2006) |
| "Nevertheless, only 44% of the affected treated their acne, although the face is the part of the body most affected." | ( Abreu, AM; Amado, JM; Loureiro, L; Massa, A; Matos, ME; Oliveira, J; Verde, A, 2006) |
| "The use of isotretinoin as a treatment for acne is related to psychiatric syndromes such as psychosis and depression." | ( Eva C, P; Herskovic M, V; Poblete A, C, 2006) |
| "CDP + BPO and ERY + Zn are effective treatments for acne but CDP + BPO has an earlier onset of action that should improve patient compliance." | ( Langner, A; Layton, A; Sheehan-Dare, R, 2007) |
| "We successfully treated a case of acne conglobata by CO(2) laser ablation to remove the top of the sinuses and their tracts." | ( Haruna, K; Hasegawa, T; Ikeda, S; Matsukura, T; Mizuno, Y; Muramatsu, S; Ogawa, H; Suga, Y; Tsuchihashi, H, 2007) |
| "A major issue in treating acne in individuals of color is the need to treat and prevent postinflammatory hyperpigmentation (PIH), which is common in this population." | ( Taylor, SC, 2007) |
| "A requirement for developing successful treatments for postacne scarring is a greater understanding of its pathogenesis, variability among afflicted individuals, and the inflammatory mediators and immunology of the scarring process." | ( Baron, JA; Goodman, GJ, 2007) |
| "CDP + BPO and ADA are both effective treatments for acne, but CDP + BPO has a significantly earlier onset of action, is significantly more effective against inflamed and total lesions and is better tolerated, which should improve patient compliance." | ( Ambroziak, M; Chu, A; Goulden, V; Langner, A, 2008) |
| "In the treatment of facial acne vulgaris, tazarotene plus clindamycin offers significantly greater efficacy than tretinoin plus clindamycin and has comparable tolerability." | ( Dhawan, S; Kircik, L; Tanghetti, E; Torok, H, 2007) |
| "Under the influence of complex treatment of acne disease, statistically important increase of active neutrophiles amount have been observed in comparison with data before treatment and decrease of spontaneous and stimulated indexes of nitroblue-tetrozolit test." | ( Davatdarova, M; Kazimov, A, 2008) |
| "Instead, successful treatment of acne seems to improve both depressive and anxiety symptoms and improve quality of life." | ( Kaymak, Y; Taner, E; Taner, Y, 2009) |
| "New topical treatments for acne vulgaris are needed for patients who have tolerance problems with current treatments." | ( Bissonnette, R; Bolduc, C; Maari, C; Nigen, S; Provost, N; Rougier, A; Seité, S, 2009) |
| "Given the well-recognized difficulty in treating acne scars, the results of this case suggest that injectable PLLA may provide an improved treatment modality for resolving acne scars." | ( Palmisano, L; Sadick, NS, 2009) |
| "The potential of oral dapsone to treat acne vulgaris is well established, but the risks of serious side effects have made it an undesirable drug for use in the relatively healthy acne population." | ( Pickert, A; Raimer, S, 2009) |
| "Combination therapy for the topical treatment of acne vulgaris using benzoyl peroxide (BPO) and an antibiotic is more efficacious and better tolerated than treatment with either component alone." | ( Dhawan, SS, 2009) |
| "Isotretinoin is effective in the treatment of severe acne and rosacea." | ( Grønhøj Larsen, C; Grønhøj Larsen, F; Heidenheim, M; Held, E; Jakobsen, P; Nielsen-Kudsk, F, 2009) |
| "Direct heat treatment of P." | ( Lyte, P; Nigam, A; Southall, MD; Sur, R, 2009) |
| "Oral isotretinoin for the treatment of acne induces alterations in the conjunctival epithelium of a significant percentage of patients treated with the drug." | ( Antônio Vieira, L; Barros, Jde N; de Morais, LC; de Queiroga, IB; Melo Diniz, Mde F, 2009) |
| "This article reviews emerging treatments of acne, including topical picolinic acid, topical antibiotic dapsone, systemic zinc salts, oral antibiotic lymecycline, new formulations of and synergistic combinations of benzoyl peroxide, photodynamic therapy with topical photosensitizers and potential acne vaccines." | ( Burkhart, CN; James, KA; Morrell, DS, 2009) |
| "As the current treatment of acne is based on topical or systemic drugs, it is worth examining further the biotherapeutic activities of the GMH and selected probiotics with a view to future use as prophylactic or therapeutic synbiotics for treating acne infections." | ( Al-Ghazzewi, FH; Tester, RF, 2010) |
| "Isotretinoin is an effective treatment for acne vulgaris." | ( Akin, KO; Ertugrul, DT; Karadag, AS; Tutal, E, 2010) |
| "An alternative approach in the treatment of acne vulgaris is photodynamic therapy (PDT) that uses light and aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) production to eradicate Propionibacterium acnes found in acne lesions." | ( Barolet, D; Boucher, A, 2010) |
| "Isotretinoin has revolutionized the treatment of acne by improving the cosmetic outcome and decreasing the psychological damage." | ( Akbari, MR; Gheisari, M; Kavand, S; Roodsari, MR; Saeedi, M; Sarrafi-rad, N, 2010) |
| "Isotretinoin is very effective in the treatment of severe acne." | ( De Smet, PA; Dufour, M; Rodenburg, E; Straus, SM; Stricker, BH; Teichert, M; Visser, LE, 2010) |
| "The latest guidelines in the treatment of acne recommend a dose of 50-100 mg, once or twice a daily for the non-modified release minocycline, and 1 mg/kg daily for the new extended-release formulation." | ( Maffeis, L; Veraldi, S, 2010) |
| "Retinoids are widely used to treat acne in patients with underlying systemic diseases." | ( Gorpelioglu, C; Ozol, D; Sarifakioglu, E, 2010) |
| "The first-line treatments for acne vulgaris are conventional topical and/or oral medications." | ( Anderson, RR; Lopes, JD; Sakamoto, FH, 2010) |
| "Topical treatment of acne vulgaris on the back is challenging largely due to the extensive broad surface with difficult to reach areas." | ( Leyden, JJ, 2010) |
| "Many clinicians use these peels in the treatment of acne and acne-prone oily skin." | ( Berson, DS; Cohen, JL; Dréno, B; Fischer, TC; Perosino, E; Poli, F; Rendon, MI; Roberts, WE; Starker, I; Viera, MS; Wang, B, 2011) |
| "The most effective treatment of severe acne is isotretinoin." | ( Wolkenstein, P, 2010) |
| "Isotretinoin is an efficacious treatment for acne, but has been controversially linked with depression." | ( Darvay, A; Gillison, F; Hickey, JR; Lovell, CR; McGrath, EJ; Skevington, SM, 2010) |
| "Tretinoin is widely used in the treatment of acne." | ( Pillai, R; Torok, HM, 2011) |
| "Whereas the standard approach to the treatment of acne vulgaris has involved both systemic and topical antibiotics and topical agents such as benzoyl peroxide, problems exist due to side effects, drug resistance and lack of compliance." | ( Flint, C; Smalley, H; Wainwright, M, 2011) |
| "However, there has been no study of treatment of acne using a dual mode (quasi-long pulse and Q-switched mode) 1064-nm Nd:YAG laser assisted with a topically applied carbon suspension." | ( Ahn, CH; Hong, JS; Jung, JY; Kwon, HH; Suh, DH; Yoon, JY, 2012) |
| "A 35-year-old woman had been treated for acne since the age of 22 years, as part of which she received two courses of oral isotretinoin." | ( Celerier, P; Fenot, M; Maillard, H; Rivet, J; Sierra-Fortuny, S, 2011) |
| "Diverse options are available for the treatment of acne." | ( Neumeister, C; Schwantes, U; Wilhelm, D; Wilhelm, KP; Zsolt, I, 2012) |
| "Systemic isotretinoin and antibiotic treatments in acne patients precisely caused variations in the microbial floras of several sites of the body, while isotretinoin was commonly more responsible than antibiotics." | ( Başak, PY; Cetin, ES; Gürses, I; Ozseven, AG, 2013) |
| "IPL serves a useful role in the treatment of acne vulgaris and could reduce treatment costs and pill burden." | ( Annie Malathy, P; Gomathi, N; Mohanan, S; Parveen, B, 2012) |
| "Systemic isotretinoin effectively treats all forms of acne vulgaris." | ( Sinclair, W, 2012) |
| "Dapsone 5% gel for the topical treatment for acne vulgaris was recently introduced in Canada." | ( Tan, J, 2012) |
| "The success rates of conventional treatments to acne vulgaris are limited because of intolerance and resistance." | ( Mei, X; Piao, Y; Shi, W, 2013) |
| "Azelaic acid (AzA) is used in the treatment of acne." | ( Ascensão, L; Baptista, M; Candeias, S; Gomes, A; Martinho, N; Pinto, P; Reis, CP; Rijo, P, 2013) |
| "A new follicularly targeted topical treatment for acne based on this approach should be well tolerated and highly effective." | ( Cove, JH; Eady, EA; Layton, AM, 2013) |
| "Despite many advances in the treatments of acne vulgaris the best option is still controversial as the pathogenesis of acne is rather complex, necessitating various combination therapies." | ( El-Latif, AA; Elsaie, ML; Elshahed, AR; Hassan, FA; Mohamed, AG, 2014) |
| "Isotretinoin is the most effective treatment for acne." | ( Blasiak, RC; Burkhart, CN; Lugo-Somolinos, A; Morrell, DS; Stamey, CR, 2013) |
| "New compounds are needed to treat acne and superficial infections caused by Propionibacterium acnes and Staphylococcus aureus due to the reduced effectiveness of agents used at present." | ( Desbois, AP; Lawlor, KC, 2013) |
| "Successful treatment of acne can improve the quality of life and reduce levels of anxiety and depression in these individuals." | ( Daubney, M; Manoharan, S; Oziemski, M; Rowe, C; Ryan, A; Scott, J; Spelman, L; Wilson, P, 2014) |
| "Topical tretinoin has been a standard treatment for acne vulgaris for more than 4 decades." | ( Kircik, LH, 2014) |
| "A variety of effective treatments for acne are available, depending on the severity of the condition." | ( Gollnick, HP; Zouboulis, CC, 2014) |
| "The biggest hurdle in the treatment of acne vulgaris is patient non-compliance that is due in large part to poor tolerability to common acne medications." | ( Bhatia, AC; Jimenez, F, 2014) |
| "Lappa has shown positive effects in the treatment of acne especially of inflammatory type." | ( Manchanda, RK; Miglani, A, 2014) |
| "Currently, the treatment of acne is focused on one or more pathogenic factors: hormonal stimulation and sebaceous hypersecretion, disorder of keratinization, colonization of Propionibacterium acnes and inflammation." | ( Carlomagno, V; Casucci, G; Pezza, M, 2015) |
| "Main topical treatments for acne vulgaris are retinoids, benzoyl peroxide and antibiotics in mono or combination therapy." | ( Capizzi, R; De Waure, C; Fossati, B; Frascione, P; Guerriero, C; Masini, F; Ricci, F, 2014) |
| "Ablative CO2 fractional laser treatment for acne scarring seems to be safe regardless of isotretinoin use (10-60 mg/d)." | ( Chang, SE; Kim, HW; Kim, JE; Ko, JY; Ro, YS, 2014) |
| "The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed." | ( Rolfe, HM, 2014) |
| "Although antibiotics are a common treatment for acne, the difficulties inherent to effective antimicrobial penetration in sebum and selective antimicrobial action in the skin are compounded by increasing resistance of Propionibacterium acnes clinical isolates." | ( Agak, GW; Blacker, A; Champer, J; Deshayes, S; Kasko, AM; Kim, J; Schmidt, NW; Wong, GCL; Xian, W; Yu, Y, 2015) |
| "Current standard treatments for acne have limitations that include adverse effects and poor efficacy in many patients, making development of a more effective therapy highly desirable." | ( Armstrong, CA; Han, HM; Park, Y; Ryu, S; Song, PI, 2015) |
| "Topical retinoids are the initial treatment for acne due to their ability to treat comedones, the starting point of acne." | ( Feldman, SR; Hill, D; Narahari, S; Smith, JA, 2016) |
| "There is a need to treat acne with effective alternatives to antibiotics to reduce the likelihood of resistance." | ( Dréno, B; Efthimiou, J; Walsh, TR, 2016) |
| "Topical dapsone gel, 5% is approved for treatment of acne vulgaris but has not been studied specifically in women with skin of color (SOC; Fitzpatrick skin types IV, V, or VI)." | ( Alexis, AF; Burgess, C; Callender, VD; Gallagher, CJ; Herzog, JL; Roberts, WE; Schweiger, ES; Stockton, TC, 2016) |
| "It is a very effective agent in a treatment of acne vulgaris; however, multiple side effects related to therapy with retinoids preclude the use of isotretinoin in less severe acne vulgaris." | ( Bergler-Czop, B; Brzezińska-Wcisło, L; Miziołek, B; Stańkowska, A, 2017) |
| "The current options for the treatment of acne vulgaris present many mechanisms of action." | ( Azulay-Abulafia, L; Castro, LC; Costa, Ad; Follador, I; Mulinari-Brenner, F; Sittart, JA, 2015) |
| "Patients receiving topical treatment for acne should be evaluated regularly to ensure the timely detection and treatment of pathologic signs on the ocular surface." | ( Aslan Bayhan, S; Bayhan, HA; Çölgeçen, E; Gürdal, C, 2016) |
| "Antibiotics are a mainstay of treatment for acne, yet the emergence of resistance against the currently approved antibiotics is a serious concern." | ( Ghosh, S; Gupta, T; Kaur, SP; Sadhasivam, S; Saini, S; Sardana, K; Sengupta, S; Sinha, M, 2016) |
| "Successful treatment of acne scars is challenging." | ( McGraw, TA; Taylor, MB; Zaleski-Larsen, L, 2017) |
| "Subjects referred for treatment of acne refractory to several topical and oral regimens, including isotretinoin, were pre-treated with non-ablative fractional photothermolysis (NAFP)." | ( Lin, JY; Qureshi, S, 2017) |
| "Current guidelines for the treatment of acne are based largely on expert consensus and advocate a combination of topical agents in mild to moderate cases and reserve the use of systemic therapies for moderate to severe or refractory cases of acne." | ( Cooper, AJ; Harris, VR, 2017) |
| "The relationship between isotretinoin treatment for acne and depression is controversial." | ( Cheng, YC; Huang, YC, 2017) |
| "Isotretinoin treatment for acne does not appear to be associated with an increased risk for depression." | ( Cheng, YC; Huang, YC, 2017) |
| "Effective treatment of acne can reduce symptoms of anxiety and depression and significantly improve other physiological parameters and quality of life of these patients." | ( Babić, D; Gunarić, A; Penavić, JZ; Šimić, D, 2017) |
| "To describe the medications used for treating acne/rosacea in the Medicare population and evaluate differences in costs between specialties." | ( Kaffenberger, BH; Silverberg, JI; Zhang, M, 2017) |
| "NAFL treatment for acne scarring appears to be well tolerated within 1 month of completing isotretinoin treatment." | ( Saluja, SS; Smart, DR; Summers, EM; Tristani-Firouzi, P; Walker, ML, 2017) |
| "Recent dispensing of drugs to treat acne and concomitant dispensing of other HC were also assessed." | ( Asiimwe, A; Bezemer, ID; Herings, RMC; Penning-van Beest, FJA; Smits, E, 2017) |
| "Isotretinoin is used in the treatment of severe acne vulgaris (AV), but has controversially been associated with depression and suicide." | ( Frittelli, V; Gunnarsson, R; Rea, S; Tucker, S, 2018) |
| "Available methods for treating acne scars have varying degrees of effectiveness." | ( Casabona, G, 2018) |
| "Isotretinoin has revolutionized the treatment of severe acne vulgaris, a condition which if left untreated may result in significant socio-psychological implications for those affected." | ( Driscoll, T; Kovitwanichkanont, T, 2018) |
| "We describe the difficulties of treating acne in a series of female-to-male transgender adolescents, including concerns about potential hepatotoxicity with concomitant use of testosterone with isotretinoin or tetracyclines." | ( Campos-Muñoz, L; Conde-Taboada, A; López-Bran, E; López-De Lara, D; Rodríguez-Rojo, ML, 2018) |
| "The Guidelines for the Treatment of Acne Vulgaris of the Japanese Dermatological Association was first published in Japanese in 2008 and revised in 2016 and 2017." | ( Akamatsu, H; Furukawa, F; Furumura, M; Hayashi, N; Iwatsuki, K; Kaminaka, C; Kawashima, M; Kobayashi, M; Kono, T; Kurokawa, I; Miyachi, Y; Shimada-Omori, R; Tanioka, M; Yamamoto, Y; Yamasaki, K; Yamasaki, O, 2018) |
| "The clinical application as alternative treatment for acne is advised." | ( Chalermchai, T; Jurairattanaporn, N; Ophaswongse, S; Udompataikul, M, 2017) |
| "Considerations for treating acne in adult women include childbearing potential, pregnancy, lactation, and concomitant skin conditions." | ( Alexis, AF; Harper, JC; Stein Gold, LF; Tan, JKL, 2018) |
| "Isotretinoin is the most potent treatment for acne but paradoxical flares can occur." | ( Poli, F; Revuz, J, 2019) |
| "Laser and light treatments for acne and acne scars are plentiful but poorly supported by evidence-based medicine." | ( Baldwin, HE; Marson, JW, 2019) |
| "Topical retinoids are a first-line treatment for acne vulgaris." | ( Cline, A; Feldman, SR; Kolli, SS; Pecone, D; Pona, A, 2019) |
| "In this study, systemic antibiotic treatment of acne was associated with changes in the composition and diversity of skin microbiota, with variable rates of recovery across individual patients and parallel changes in specific bacterial populations." | ( Chien, AL; Garza, LA; Kang, S; Leung, S; Mongodin, EF; Nelson, AM; Tsai, J, 2019) |
| "Oral antibiotics are well established treatments for acne vulgaris but are associated with undesirable side effects." | ( Bonati, LM; Dover, JS, 2019) |
| "It has widely been marketed to treat acne, melasma, photoaging, and hyperpigmentation." | ( Saedi, N; Schoenberg, E; Wang, JV, 2019) |
| "PDT is more effective in treating acne when combined with a topical cream containing licochalcone A, L-carnitine and decanediol, than PDT alone." | ( Eimpunth, S; Manuskiatti, W; Suphatsathienkul, P; Tantrapornpong, P; Tavechodperathum, N; Techapichetvanich, T; Wanitphakdeedecha, R, 2020) |
| "Isotretinoin is the mainstay treatment in severe acne; however, its musculoskeletal adverse effects such as lower-back pain can be disabling." | ( Aktay Ayaz, N; Çakan, M; Karadağ, ŞG; Sönmez, HE; Tanatar, A, 2020) |
| "Existing treatments of acne vulgaris may be complicated or elicit undesirable side effects." | ( Kim, JY; Lee, HJ; Lee, WJ; Park, KD, 2020) |
| "Isotretinoin is widely used in the treatment of acne vulgaris for more than 30 years (1)." | ( Alataş, ET; Alataş, ÖD, 2020) |
| "ADVTG was found to be promising in treating acne compared with the marketed product." | ( Dubey, A; El-Zahaby, SA; G S, R; Ghate, VM; Hebbar, S; Lewis, SA; Vasanth, S, 2020) |
| "One of the ways to treat acne is by using chemical peels." | ( Deda, A; Odrzywołek, W; Wilczyński, S; Zdrada, J, 2020) |
| "Spironolactone is a safe and effective treatment of acne for women." | ( Davis, MDP; McEvoy, MT; Newman, CC; Nowsheen, S; Roberts, EE; Sartori Valinotti, JC; Sciallis, GF; Torgerson, RR; Wetter, DA, 2020) |
| "Isotretinoin is the most effective treatment for acne and has the potential for long-term clearance." | ( Landis, MN, 2020) |
| "The first-line treatments for acne vulgaris are topical and oral medications, mainly antibiotics and retinoids." | ( Artzi, O; Friedman, O; Hilerowicz, Y; Koren, A; Mehrabi, JN; Salameh, F; Ziv, R; Zur, E, 2020) |
| "Chemical peels have been used for treatment of acne vulgaris with inadequate clinical evidence." | ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "C-PDT in the treatment of acne vulgaris." | ( Liu, X; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhao, Y; Zhou, Z, 2020) |
| "Topical OXZ is a safe and effective treatment for post-acne erythema." | ( Agamia, N; Essawy, M; Kassem, A, 2022) |
| "There are different modalities of treatment of acne but there is no standard treatment free of side effects." | ( El-Halaby, AR; Gheida, SF; Hassan, GFR; Ibrahim, ZA; Mohammed, DA, 2022) |
| "Few GPs in Ireland currently initiate treatment of acne with isotretinoin, and there is suboptimal adherence to recommended monitoring." | ( Carmody, K; Nolan, D; Quinlan, D; Rouse, M, 2020) |
| "Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment." | ( Marsch, AF; Richards, P; Sui, JY; Yee, BE, 2020) |
| "Retinoids can treat both acne and PIH." | ( Bhatia, ND; Cook-Bolden, FE; Guenin, E; Werschler, WP, 2020) |
| "Spironolactone demonstrated efficacy in treating acne in adolescent females and is a safe long-term alternative to systemic antibiotics in these patients." | ( Davis, DMR; Hand, JL; Nowsheen, S; Roberts, EE; Tollefson, MM; Wetter, DA, 2021) |
| "Adapalene is a good choice in the treatment of acne with fewer side effects and high effectiveness." | ( Emam, M; Mohammad Soleymani, S; Salimi, A, 2021) |
| "Successful treatment of acne scars in ethnic skin requires procedures that are safe and effective with a low incidence of hyper or hypopigmentation postoperatively." | ( Koron, N; Taylor, MB, 2021) |
| "Current treatments for acne are often accompanied by undesirable side effects and contribute to antibiotic resistance." | ( Artounian, K; Boen, M; Bundogji, N; Hoss, E, 2021) |
| "The main barriers to care in the treatment of acne are poor adherence to therapy and lack of tolerability." | ( Emmerich, VK; Feldman, SR; Purvis, CG, 2021) |
| "Adapalene is used for treatment of acne vulgaris, a common dermatological disease." | ( Amani, A; Ehsani, A; Eslami Farsani, V; Jafarzadeh Kohneloo, A; Mehdizade Rayeni, N; Moghimi, HR; Najafi-Taher, R, 2022) |
| "The ongoing search for effective treatment of Acne vulgaris is concentrated, i." | ( Dryś, A; Golonka, I; Greber, KE; Junka, A; Musiał, W; Oleksy-Wawrzyniak, M; Paleczny, J; Sawicki, W, 2021) |
| "Peels with 30%SSA effectively treated acne and reduced facial sebum secretion without damaging the skin barrier." | ( Ariyawati, A; Chen, J; Chen, Y; Li, Y; Liu, L; Pu, Y; Shao, X; Wang, J; Zhang, L; Zhang, Y, 2022) |
| "Proper treatment of acne, coupled with mental health screening, provides the best course of action." | ( Ellington, E, 2022) |
| "Retinoids are first-line therapy in the treatment of acne vulgaris." | ( Feldman, SR; Mohney, LA; Singh, R, 2022) |
| "Food and Drug Administration for the treatment of acne." | ( Liu, H; Sun, L; Wang, X; Wang, Z; Zhang, F, 2022) |
| "Dapsone gel is effective in treating acne, and there is no significant difference in adverse events compared with other drugs." | ( Liu, H; Sun, L; Wang, X; Wang, Z; Zhang, F, 2022) |
| "It could be an alternative treatment of acne with more minor side effects." | ( Kamanamool, N; Kanokrungsee, S; Sathikulpakdee, S; Taweechotipatr, M; Udompataikul, M; Vitheejongjaroen, P, 2022) |
| "The action mechanism of CPT treatment of acne was investigated by the strategy of microbiome integration with lipidomics." | ( Chen, T; Hu, Y; Jiang, C; Liu, L; Liu, Q; Shen, C; Shen, Q; Wang, Y; Wang, Z; Wu, Y; Xue, Y; Zeng, Q; Zhu, H; Zhu, Z, 2022) |
| "Although there are many approaches to treating acne, active-duty service members and military dermatologists must weigh multiple additional challenging factors when selecting a therapy." | ( Brahe, C; Park, AM, 2022) |
| "Various treatments for acne vulgaris exist, but little is known about their comparative effectiveness in relation to acne severity." | ( Arnold, S; Berg, L; Bromham, N; Daly, CH; Deshpande, S; Dworzynski, K; Fou, L; Healy, E; Mavranezouli, I; Phillippo, DM; Rafiq, M; Ravenscroft, JC; Welton, NJ; Wilcock, J; Wood, D; Xu, J, 2022) |
| "Multiple approaches are used to treat acne scars, but some are expensive, ineffective, and cause complications." | ( Chen, J; Chen, JY; Chen, YM; Liu, L; Pu, YH; Shao, XY; Zhang, LZ; Zhang, YJ, 2022) |
| "A wide variety of treatments for acne, topical and systemics, could be prescribed, depending on its degree of severity." | ( Annunziata, MC; Di Vico, F; Fabbrocini, G; Genco, L; Nastro, F; Villani, A, 2022) |
| "Some topical treatments for acne used in combination, such as blue light and topical antibiotics (such as metronidazole) by needle-free jet injection (NFJI), are becoming prevalent in clinical practice, but the efficacy remains uncertain." | ( Chen, F; Gao, L; Huang, X; Jiang, L; Lao, Y; Li, N; Lu, J; Lv, L; Yan, W; Yang, F; Yi, L; Zhang, B, 2023) |
| "Protocols for treating acne with isotretinoin have varied widely because some factors associated with relapse and treatment duration have not yet been fully determined." | ( Hassan, F; Ismail, M; Kassem, B, 2022) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Oral spironolactone is used for treating acne vulgaris due to its antiandrogenic properties and inhibition of sebogenesis." | ( Abbas, S; Ahmed, A; Eljack, MMF; Imran, L; Khan, Z; Kheljee, AZ; Munir, S; Rehan, ST; Tahir, MJ, 2023) |
| "Metformin is commonly used for treatment of acne in patients with polycystic ovarian syndrome (PCOS)." | ( De, D; Dutta, P; Handa, S; Kamboj, P; Kaushik, A; Pal, A; Saikia, UN, 2023) |
| "Oral vitamin A is efficacious for the treatment of acne vulgaris, although the available studies have limited controls and outcomes." | ( Cook, MK; Feldman, SR; Perche, PO, 2022) |
| "Minocycline is widely used in the treatment of acne, rosacea, and other inflammatory skin diseases." | ( Chen, Q; Kong, M; Song, Z; Wang, H; Yang, X, 2023) |
| "One week after the last treatment, the acne lesion counts were significantly decreased in both groups (56." | ( Huh, CH; Kim, BR; Kim, M; Na, JI; Shin, JW, 2023) |
| "The RNA-seq analysis of prodigiosin-treated C." | ( Jeong, SK; Kim, HJ; Lee, MS; Lee, SJ, 2023) |
| "Topical treatment of acne would be advantageous by reducing the risk of systemic adverse drug reactions." | ( Daneshamouz, S; Ghasemiyeh, P; Heidari, R; Mohammadi-Samani, S; Moradishooli, F; Niroumand, U, 2023) |
| "Azithromycin is currently used for the treatment of acne, with different dosing regimens for patients who cannot receive traditional treatment based on practice guidelines." | ( Alasqah, MA; Alhubaishi, AA; Alkahtani, RM; Almuwinea, AI; Alnajjar, LI; Bakkari, S, 2023) |