Classes > carbacephem

Page last updated: 2024-08-05 13:21:59

carbacephem

Any member of a group of synthetic antibiotics, similar to cephems but with carbon substituted for the sulfur; all possessing an acylated amine functionality at C-6 and (S,R) stereochemistry at C-6 and C-7.

ChEBI ID: 55504

Members (2)

Member	Definition	Role
ly 163892	A synthetic "carba" analogue of cefaclor, with carbon replacing sulfur at position 1. Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria.	loracarbef zwitterion; loracarbef
ly 163892	The zwitterionic form of loracarbef.	loracarbef zwitterion; loracarbef

Research

Studies (122)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	13 (10.66)	18.7374
1990's	85 (69.67)	18.2507
2000's	11 (9.02)	29.6817
2010's	12 (9.84)	24.3611
2020's	1 (0.82)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	36 (26.09%)	5.53%
Reviews	20 (14.49%)	6.00%
Case Studies	4 (2.90%)	4.05%
Observational	0 (0.00%)	0.25%
Other	78 (56.52%)	84.16%