Roles > antidote to sarin poisoning
Page last updated: 2024-08-05 15:13:57
antidote to sarin poisoning
A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
ChEBI ID: 136860
Members (3)
| Member | Definition | Class |
|---|
| biperiden | A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease. | biperiden |
| duodote | A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2. | pralidoxime |
| pralidoxime | A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2. | pralidoxime |
Research
Studies (1,098)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 354 (32.24) | 18.7374 |
| 1990's | 241 (21.95) | 18.2507 |
| 2000's | 231 (21.04) | 29.6817 |
| 2010's | 217 (19.76) | 24.3611 |
| 2020's | 55 (5.01) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 111 (9.49%) | 5.53% |
| Reviews | 52 (4.44%) | 6.00% |
| Case Studies | 209 (17.86%) | 4.05% |
| Observational | 1 (0.09%) | 0.25% |
| Other | 797 (68.12%) | 84.16% |
Protein Targets (15)
Potency Measurements
Inhibition Measurements
Activation Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Acetylcholinesterase | Homo sapiens (human) | Kd | 140.0000 | 1 | 1 |
Other Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Acetylcholinesterase | Homo sapiens (human) | K | 400.0000 | 4 | 4 |