Page last updated: 2024-11-12

spergualin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

spergualin: from bacillus isolated from soil sample collected at Ohira-san [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID15916864
CHEMBL ID3753954
CHEBI ID80701
MeSH IDM0104629

Synonyms (13)

Synonym
heptanamide, 7-((aminoiminomethyl)amino)-n-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-3-hydroxy-, (s-(r*,r*))-
heptanamide, 7-((aminoiminomethyl)amino)-n-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-3-hydroxy-
antibiotic bmg 162af2
spergualin
80902-43-8
n-[2-[4-(3-aminopropylamino)butylamino]-1-hydroxy-2-oxoethyl]-7-(diaminomethylideneamino)-3-hydroxyheptanamide
unii-71o2a541cu
71o2a541cu ,
heptanamide, 7-((aminoiminomethyl)amino)-n-((1s)-2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-3-hydroxy-, (3s)-
CHEBI:80701
CHEMBL3753954
Q27149734
(3s)-n-[(1s)-2-[4-(3-aminopropylamino)butylamino]-1-hydroxy-2-oxoethyl]-7-(diaminomethylideneamino)-3-hydroxyheptanamide

Research Excerpts

Overview

Spergualin is a new antitumor antibiotic which has a very unique structure.

ExcerptReferenceRelevance
"Spergualin is a new antitumor antibiotic which has a very unique structure. "( [Spergualin, a new antitumor antibiotic].
Takeuchi, T, 1987
)
2.63
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
N-acyl-amino acidA carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID1269976Antimicrobial activity against Haemophilus influenzae ATCC 51907 after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
AID1269979Antimicrobial activity against Bacillus subtilis 168 after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
AID1269980Antimicrobial activity against Staphylococcus aureus RN4220 after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
AID1269975Antimicrobial activity against Escherichia coli K-12 MG1655 after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
AID1269977Antimicrobial activity against Bacillus anthracis 34F2 Sterne after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
AID1269978Antimicrobial activity against Bacillus cereus ATCC 11778 after 24 hrs by double dilution method2015MedChemComm, May-01, Volume: 6, Issue:5
Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (34)

TimeframeStudies, This Drug (%)All Drugs %
pre-199026 (76.47)18.7374
1990's3 (8.82)18.2507
2000's2 (5.88)29.6817
2010's3 (8.82)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index16.02 (24.57)
Research Supply Index3.58 (2.92)
Research Growth Index4.43 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (16.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews4 (11.43%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other31 (88.57%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]