tetracycline and Urinary-Calculi

Diagnostic and therapeutic drugs may enhance urolithiasis in one or a combination of ways, including: (1) alteration of urine pH in such fashion as to create an environment that increases the solubility of some lithogenic substances, (2) alteration of glomerular filtration rate, tubular reabsorption, and tubular secretion of drugs of endogenous substances so as to enhance promoters or impair inhibitors of urolithiasis, and (3) precipitation (e.g., drugs or their metabolites) to form a portion or all of a urolith.

Topics: Allopurinol; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Cat Diseases; Cats; Dog Diseases; Dogs; Enzyme Inhibitors; Fluoroquinolones; Primidone; Sulfonamides; Tetracycline; Urinary Calculi; Xanthine Oxidase

Metabolic disorders, medication, and diagnostic agents may be associated with urolithiasis in dogs. Examples of uroliths that have been uncommonly encountered in dogs include xanthine, dolomite, tetracycline, and sulfonamides. Detection of these and other apparently uncommon uroliths requires a high index of suspicion and proper methods of analysis.

Topics: Adenine; Animals; Calcium Carbonate; Dog Diseases; Dogs; Oxypurinol; Sulfonamides; Tetracycline; Triamterene; Urinary Calculi; Xanthines

Topics: Anti-Bacterial Agents; Apatites; Fluorescence; Humans; Protein Synthesis Inhibitors; Tetracycline; Urinary Calculi

Topics: Animals; Calcium Carbonate; Calcium Phosphates; Chemistry Techniques, Analytical; Dogs; Fluorescence; Fluorometry; Magnesium; Oxalates; Oxytetracycline; Tetracycline; Tetracyclines; Toxicology; Ultraviolet Rays; Urinary Calculi