Cystitis, Interstitial

A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency.

Synonym
Cystitis, Interstitial

Excerpt	Reference
"Interstitial cystitis is a urologic disorder with protean pelvic manifestations (urologic, gynecologic, gastroenterologic) and variable prevalence."	( Sant, GR, 1997)
"Interstitial cystitis is a particular type of cystitis with clear urine, essentially observed in women."	( Lépinard, V, 1998)
"Interstitial cystitis is a regularly appearing urinary disorder, especially in female patients."	( Fouchier, SM; Levens, WJ; Pelikan, Z; van Oers, JA, 1999)
"The etiology of interstitial cystitis is unknown."	( Chai, TC; Johnson, HW; Keay, S; Shoenfelt, JL; Warren, JW; Zhang, CO, 2000)
"A proposed cause of interstitial cystitis is increased bladder permeability but to our knowledge this theory has not been proved by direct testing."	( Bhavanandan, VP; Erickson, DR; Harmon, N; Herb, N; Ordille, S, 2000)
"Interstitial cystitis is the most therapeutically frustrating condition of the urinary tract."	( Emerson, L; Morales, A; Nickel, JC, 1996)
"The etiology of interstitial cystitis is unknown."	( Hise, MK; Keay, S; Kleinberg, M; Warren, JW; Zhang, CO, 2000)
"The diagnosis of interstitial cystitis is a diagnosis of exclusion."	( Nickel, JC, 2000)
"Interstitial cystitis is a chronic urological syndrome affecting humans and domestic animals, including cats (feline interstitial cystitis)."	( Buffington, CA; Pacak, K, 2001)
"Interstitial cystitis is a disorder of the bladder characterized by urgency and frequency of urination, and pelvic pain."	( Freid, RM; Hom, D; Moldwin, RM; Rofeim, O, 2001)
"Interstitial cystitis is a chronic, severely debilitating disease of the urinary bladder."	( Metts, JF, 2001)
"Interstitial cystitis is a disease characterized by pain occurring as the urinary bladder is gradually filling up."	( Amarenco, G; Haab, F; Hermieu, JF, 2002)
"Interstitial cystitis is a chronic syndrome affecting humans and domestic animals, including cats (feline interstitial cystitis)."	( Buffington, CA; Somogyi, GT; Teng, B, 2002)
"Interstitial cystitis is a relatively common disorder that can be treated successfully in the majority of cases."	( Parsons, CL, 2004)
"Interstitial cystitis is a painful bladder condition of unknown etiology and poorly understood pathophysiology."	( Antoci, JP; Diokno, AC; Evans, RJ; Forrest, JB; Frumkin, LR; Griebling, TL; Jacoby, K; Mosbaugh, PG; O'Reilly, KJ; Payne, CK; Perez-Marrero, R; Vasavada, SP; Whitmore, KE; Yu, AS, 2005)
"Interstitial cystitis is more common than previously thought and is often diagnosed only when pain, frequency, and urgency become continuous and severe."	( Page, S; Parsons, CL; Rosenberg, M, 2005)
"Interstitial cystitis is a very rare disease which is characterized by cystitis-symptoms with normal urinary finding and non-effectiveness of antibiotics."	( Nakamura, Y; Ogawa, H; Sakakura, N; Tokinaga, K; Yamashita, M, 2005)
"Interstitial cystitis is an enigmatic and frustrating condition to manage as a physician and to cope with as a patient."	( Jones, A; Kelada, E, 2007)
"Interstitial cystitis is a painful bladder disease characterized by urgency, frequency and variable inflammation but there is no curative therapy."	( Boucher, W; Cao, J; Kempuraj, D; Papaliodis, D; Theoharides, TC, 2007)
"Interstitial cystitis is a condition with a poorly understood etiology and, consequently, various treatment options have been described in the literature, with a less than optimal outcome."	( Jawade, KK; Taneja, R, 2007)
"Interstitial cystitis is a sterile bladder inflammatory disease characterized by pelvic pain, urinary urgency and frequency."	( Boucher, W; Cohen, MS; Kempuraj, D; Kotsinyan, V; Papaliodis, D; Stern, JM; Theoharides, TC, 2008)
"Interstitial cystitis is associated with substantial costs and health care resource utilization."	( Chen, A; Lunacsek, OE; Sand, PK; Stanford, EJ; Wan, GJ, 2008)
"The so-called interstitial cystitis is a chronic pain syndrome rather than a purely end organ disease of the urinary bladder."	( Binder, I; Rossbach, G; van Ophoven, A, 2008)
"Interstitial cystitis is characterized by over 6 months of chronic pain, pressure and discomfort felt in the lower pelvis or bladder."	( Bruetman, JE; Comercio, LP; Finn, BC; González, M; Quezel, M; Young, P, 2010)
"Interstitial cystitis is a debilitating bladder inflammation disorder."	( Casu, MA; Lazzari, P; Mastinu, A; Tambaro, S, 2014)
"Interstitial cystitis is regarded as a heterogenous syndrome with two distinguishable forms: the non-ulcer and the classic form of interstitial cystitis, the latter with Hunner's lesions; or bladder pain syndrome type 3C and non-Hunner bladder pain syndrome, respectively."	( Delbro, D; Fall, M; Lindholm, C; Logadottir, Y; Peeker, R, 2014)
"Interstitial cystitis is a syndrome characterized by detrusor overactivity and chronic inflammation of the bladder."	( Bozkurt, TE; Denizalti, M; Durlu-Kandilci, NT; Sahin-Erdemli, I; Simsek, G, 2018)
"Interstitial cystitis is a chronic inflammatory condition of the urinary bladder with an unclear etiology."	( Berger, G; Burkovskiy, I; Chinnadurai, A; Cox, A; Lehmann, C; Lynch, M; Zhou, J, 2019)

Excerpt	Reference
"Most patients with interstitial cystitis have urinary epithelial dysfunction, as indicated by a positive intravesical potassium sensitivity test."	( Albo, M; Parsons, CL, 2002)

Excerpt	Reference
"Interstitial cystitis affects about 0."	( Nickel, JC, 2000)

Excerpt	Reference
"To review the newer methods of treatment of interstitial cystitis using techniques that coat the epithelium to maintain its integrity relative to permeability."	( Parsons, CL, 1997)
"A highly effective treatment for interstitial cystitis (IC) remains elusive."	( Chai, TC; Keay, S; Warren, JW; Zhang, C, 2000)
"Oral treatments of interstitial cystitis include pentosan polysulfate, tricyclic antidepressants and antihistamines."	( Metts, JF, 2001)
"Hydrodistension is the first choice of treatment for interstitial cystitis because it allows for diagnosis, bladder biopsy and treatment."	( Andoh, M; Murayama, T; Yamada, T, 2003)
"Current medications used in the treatment of interstitial cystitis (IC) have limited efficacy."	( Kuo, HC; Peng, CH, 2007)
"After 12 weeks treatment both Interstitial Cystitis Symptom and Problem Index (ICSI/ICPI), pelvic pain and Urgency/Frequency Symptom Scale (PUF) showed a mean significant improvement, which was maintained thereafter."	( Anghileri, A; Cervigni, M; Gardella, B; Lo Voi, R; Nasta, L; Natale, F; Porru, D; Rovereto, B; Spinillo, A; Tinelli, C, 2008)
"Amitriptyline is frequently used to treat patients with interstitial cystitis/painful bladder syndrome."	( Burks, DA; Cen, L; Chai, TC; FitzGerald, MP; Foster, HE; Hanno, PM; Kreder, KJ; Kusek, JW; Landis, JR; Lukacz, ES; Mayer, RD; Nickel, JC; Nyberg, LM; Payne, CK; Peters, KM; Propert, KJ; Yang, CC; Yang, W, 2010)
"To share our experiences in the treatment of interstitial cystitis, additionally, to comment on the therapeutic response of treatment used."	( Flores-Carreras, O; González-Ruiz, MI; Martínez-Espinoza, CJ, 2011)
"To further investigate the efficacy of treatment of interstitial cystitis that had been refractory to standard treatment with sympathomimetic amines."	( Check, JH; Cohen, G; Cohen, R; Dipietro, J; Steinberg, B, 2013)
"DMSO is used as a treatment for interstitial cystitis and this study examined the effects of luminal DMSO treatment on bladder function and histology."	( Chess-Williams, R; McDermott, C; Smith, KJ, 2014)
"AQX-1125 may be a potential new treatment for interstitial cystitis/bladder pain syndrome."	( Davis, E; Egerdie, B; Evans, R; Mackenzie, L; Nickel, JC; Shrewsbury, SB, 2016)
"We assessed lipotoxin to treat refractory interstitial cystitis/bladder pain syndrome."	( Chuang, YC; Kuo, HC, 2017)
"There is currently no effective treatment for interstitial cystitis / bladder pain syndrome (IC/BPS) and thus seriously reduces the quality of life of patients."	( Hei, S; Lai, C; Li, K; Li, Z; Liu, C; Xu, K, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	16 (2.48)	23.3326
1990's	58 (8.99)	12.5806
2000's	259 (40.16)	18.1394
2010's	222 (34.42)	28.8240
2020's	90 (13.95)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	medium	5	1
acetic acid	medium	2	1
acetone	low	1	0
carbon monoxide	low	1	0
aminooxyacetic acid	low	1	0
hydrochloric acid	low	5	0
phloroglucinol	low	1	0
hydrogen sulfide	low	1	0
cytosine	low	2	0
glycine	low	1	0
histamine	low	6	0
hydrogen	medium	1	1
pipecolic acid	low	1	0
thioctic acid	medium	2	1
melatonin	low	3	0
nickel	low	1	0
nitrates	low	1	0
nitrites	low	2	0
purine	low	1	0
pyridoxine	low	1	0
taurine	low	1	0
urea	low	1	0
normetanephrine	low	1	0
menthol	low	2	0
hydroxyindoleacetic acid	low	1	0
theophylline	low	1	0
azathioprine	low	1	0
bisindolylmaleimide i	low	1	0
bumetanide	low	1	0
bupivacaine	medium	5	2
caffeine	low	1	0
carbazochrome	low	1	0
celecoxib	low	2	0
cetirizine	low	2	0
cetyltrimethylammonium ion	low	1	0
cimetidine	low	7	0
ciprofloxacin	low	1	0
clonidine	low	1	0
doxazosin	low	1	0
doxepin	medium	1	1
emodin	low	1	0
erythrosine	low	1	0
gabapentin	medium	6	1
guaifenesin	low	3	0
1-(5-isoquinolinesulfonyl)-2-methylpiperazine	low	1	0
hydroxychloroquine	low	1	0
hydroxyzine	medium	13	1
imipramine	low	1	0
indomethacin	low	1	0
ketamine	medium	13	1
loxoprofen	low	1	0
mepivacaine	low	1	0
methantheline	low	1	0
metronidazole	low	1	0
naftopidil	low	1	0
nefopam	low	1	0
nitroglycerin	low	1	0
ofloxacin	low	1	0
oxybutynin	medium	7	2
oxyphenbutazone	low	1	0
palmidrol	low	1	0
phenazopyridine	low	6	0
potassium chloride	medium	26	8
primidone	low	1	0
procaine	low	1	0
suramin	low	1	0
tiaprofenic acid	low	6	0
tripelennamine	low	1	0
urethane	low	2	0
prednisolone	low	11	0
estriol	low	2	0
thymidine	low	2	0
hydroxyproline	low	2	0
dextroamphetamine	low	4	0
carbachol	low	3	0
prednisone	medium	5	1
adrenochrome	low	1	0
glutamine	low	1	0
carbostyril	low	1	0
phenylephrine	low	1	0
tyrosine	low	1	0
methylene blue	low	2	0
phenylalanine	low	2	0
colchicine	low	1	0
dimethyl sulfone	low	1	0
sodium citrate, anhydrous	low	1	0
histidine	low	1	0
medroxyprogesterone acetate	low	1	0
tryptophan	low	1	0
arginine	medium	7	4
pantothenic acid	low	1	0
methylprednisolone	low	5	0
tolonium chloride	low	1	0
xanthenes	low	1	0
pyrrolidonecarboxylic acid	low	1	0
cyclohexanol	medium	5	2
thiophenes	medium	2	1
catechin	medium	2	1
thiazoles	low	1	0
evans blue	low	1	0
citrulline	low	1	0
phenylpropanolamine	medium	4	1
malondialdehyde	low	4	0
trinitrobenzenesulfonic acid	low	2	0
erythromycin	low	1	0
levonorgestrel	low	1	0
potassium citrate	low	1	0
d-alpha tocopherol	low	1	0
dronabinol	low	1	0
amiloride	low	1	0
fluorescein	low	3	0
streptomycin	low	1	0
neodymium	medium	1	1
silver	low	1	0
galactosamine	low	1	0
phosphoric acid, trisodium salt	medium	1	1
trolamine salicylate	low	4	0
rhamnose	low	1	0
cromolyn sodium	low	4	0
sodium bisulfide	low	1	0
phenyl acetate	medium	6	1
triamcinolone	medium	7	2
substance p	medium	16	1
desogestrel	low	1	0
fomesafen	low	5	0
cidofovir anhydrous	low	2	0
duloxetine hydrochloride	medium	2	1
glucose, (beta-d)-isomer	low	6	0
epigallocatechin gallate	medium	2	1
suplatast tosilate	medium	8	2
4-phenylbutylamine	low	1	0
phenylacetylglutamine	low	1	0
p-methoxy-n-methylphenethylamine	low	3	0
fulvestrant	low	1	0
methoctramine	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
imatinib mesylate	low	2	0
cyclic adp-ribose	low	1	0
1,9-dimethylmethylene blue	low	1	0
naadp	low	1	0
methotrexate	low	1	0
dexpanthenol	low	1	0
allotrap	low	1	0
proline	low	1	0
angiotensin ii	low	1	0
organophosphonates	low	2	0
propargylglycine	low	1	0
8-tert-butyl-6,7-dihydropyrrolo(3,2-e)-5-methylpyrazolo(1,5-a)pyrimidine-3-carbonitrile	low	1	0
cortisone	low	5	0
3-nitrotyrosine	low	1	0
anisomycin	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	3	0
n-acetylneuraminic acid	low	2	0
bradykinin	low	3	0
glucosamine	low	1	0
elastin	low	1	0
carnosine	low	1	0
oxytocin	low	1	0
inositol 1,4,5-trisphosphate	low	1	0
ryanodine	low	1	0
arachidonic acid	low	2	0
tacrolimus	low	4	0
eicosapentaenoic acid	medium	1	1
mycophenolic acid	medium	1	1
zithromax	low	1	0
y 27632	low	1	0
texas red	low	1	0
enkephalin, leucine	low	3	0
sodium bicarbonate	medium	4	1
bromochloroacetic acid	low	3	0
stilbenes	low	1	0
leuprolide	low	1	0
curcumin	low	1	0
capsaicin	low	13	0
chlorogenic acid	low	1	0
nadp	low	1	0
erythronic acid	low	1	0
ranitidine	low	1	0
ha 1100	low	1	0
2,3,4-tri-o-acetylarabinopyranosyl isothiocyanate	low	1	0
oxychlorosene	medium	8	1
ovalbumin	low	5	0
jhw 015	low	1	0
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide	low	1	0
sphingosine	low	1	0
quercetin	medium	1	1
dinoprostone	low	9	0
linoleic acid	low	1	0
calcitriol	low	1	0
alprostadil	low	1	0
cholecalciferol	low	1	0
leukotriene d4	low	1	0
leukotriene e4	low	2	0
genistein	low	1	0
montelukast	low	5	0
humulene	low	1	0
anandamide	low	1	0
tranilast	low	5	0
glyceryl 2-arachidonate	low	1	0
misoprostol	medium	1	1
sphingosine 1-phosphate	low	2	0
naloxone	low	1	0
oxymorphone	low	1	0
morphine	low	1	0
arachidonyl-2-chloroethylamide	low	1	0
kallidin	low	1	0
iloprost	low	1	0
neurokinin a	low	1	0
neurokinin b	low	1	0
ag-490	low	1	0
resiniferatoxin	medium	15	2
carbocyanines	low	1	0
dizocilpine maleate	low	1	0
axitinib	low	1	0
nitrofurantoin	low	1	0
ym 976	low	1	0
gadolinium dtpa	low	2	0
sq-23377	low	1	0
rs 504393	low	1	0
lactulose	low	1	0
bxl628	low	1	0
rifamycins	low	1	0
shionone	low	1	0
nociceptin	low	1	0
phosphatidylcholines	low	1	0
chitosan	low	1	0
ro13-9904	low	1	0
tolterodine tartrate	medium	4	1
gw 1000	low	1	0
glycolipids	medium	3	1
interleukin-8	low	8	0
mme	low	1	0
chondroitin	low	1	0
heparitin sulfate	low	2	0
ascorbic acid	low	1	0
tetracycline	low	1	0
piroxicam	medium	1	1
epidermal growth factor	medium	21	1
transforming growth factor beta	low	7	0
s-nitroglutathione	low	1	0
hyaluronoglucosaminidase	low	2	0
vitamin b 12	low	1	0
cyclosporine	medium	21	6
chondroitin sulfates	medium	39	11
exudates	low	1	0
cyclic gmp	low	4	0
folic acid	low	1	0
tegaserod	low	1	0
sildenafil citrate	medium	3	1
aprepitant	low	2	0
8-hydroxy-2'-deoxyguanosine	low	1	0
defibrotide	low	1	0
eye	low	1	0
metallothionein	low	1	0
dinitrobenzenes	low	1	0
preproenkephalin	low	3	0
pyrimidinones	low	1	0

Protein Targets (2,103)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	43	0	0	43
thioredoxin reductase	39	0	0	39
ATAD5 protein, partial	30	0	0	30
GLS protein	30	0	0	30
TDP1 protein	68	0	0	68
regulator of G-protein signaling 4	25	0	0	25
67.9K protein	12	0	0	12
Parkin	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	18	0	0	18
IDH1	29	0	0	29
euchromatic histone-lysine N-methyltransferase 2	74	0	0	74
nuclear factor erythroid 2-related factor 2 isoform 2	21	0	0	21
huntingtin isoform 2	5	0	0	5
ras-related protein Rab-9A	9	0	0	9
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
survival motor neuron protein isoform d	20	0	0	20
D(1A) dopamine receptor	5	0	0	5
Ataxin-2	26	0	0	26
ATP-dependent phosphofructokinase	30	0	0	30
Chain A, Cruzipain	18	0	0	18
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	11	0	0	11
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
phosphopantetheinyl transferase	28	0	0	28
pyruvate kinase PKM isoform a	4	0	0	4
geminin	60	0	0	60
Glycoprotein hormones alpha chain	2	0	0	2
Guanine nucleotide-binding protein G	7	0	0	7
Tubulin--tyrosine ligase	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	30	0	0	30
Chain A, HADH2 protein	26	0	0	26
Chain B, HADH2 protein	26	0	0	26
Chain A, 2-oxoglutarate Oxygenase	24	0	0	24
Chain A, TGF-beta receptor type-1	0	1	0	1
Luciferase	31	0	0	31
USP1 protein, partial	37	0	0	37
aldehyde dehydrogenase 1 family, member A1	43	0	0	43
EWS/FLI fusion protein	26	0	0	27
cytochrome P450 2D6 isoform 1	14	0	0	14
cytochrome P450 2C19 precursor	16	0	0	16
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	25	0	0	25
mitogen-activated protein kinase 1	18	0	0	18
tyrosine-protein kinase Yes	4	0	0	4
cytochrome P450 3A4 isoform 1	30	0	0	30
histone acetyltransferase KAT2A isoform 1	20	0	0	20
lethal factor (plasmid)	18	0	0	18
Serine/threonine-protein kinase PLK4	0	2	3	5
Serine/threonine-protein kinase 25	0	0	2	2
Gamma-aminobutyric acid receptor subunit pi	30	4	0	34
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase RIO3	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	3	3
Aurora kinase A	0	0	3	3
Cyclin-G-associated kinase	0	0	3	3
Serine/threonine-protein kinase DCLK1	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	1	0	9
3-phosphoinositide-dependent protein kinase 1	0	2	2	4
Death-associated protein kinase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	3	3
NUAK family SNF1-like kinase 1	0	1	2	3
Tyrosine-protein kinase JAK2	0	1	3	4
Ribosomal protein S6 kinase alpha-5	0	1	3	4
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Serine/threonine-protein kinase PAK 3	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	1	3	4
Cyclin-dependent kinase 14	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	0	3	3
Tyrosine-protein kinase ABL1	0	4	5	9
Epidermal growth factor receptor	0	5	3	8
RAF proto-oncogene serine/threonine-protein kinase	0	0	2	2
Receptor tyrosine-protein kinase erbB-2	0	1	2	3
High affinity nerve growth factor receptor	0	1	5	6
Insulin receptor	0	0	3	3
Tyrosine-protein kinase Lck	0	1	4	5
Tyrosine-protein kinase Fyn	0	2	4	6
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Macrophage colony-stimulating factor 1 receptor	0	0	2	2
Tyrosine-protein kinase Yes	0	1	3	4
Tyrosine-protein kinase Lyn	0	0	3	3
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	3	4
Insulin-like growth factor 1 receptor	0	1	3	4
Hepatocyte growth factor receptor	0	3	3	6
Tyrosine-protein kinase HCK	0	0	3	3
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	0	3	3
Tyrosine-protein kinase Fgr	0	0	2	2
Mast/stem cell growth factor receptor Kit	0	2	3	5
Serine/threonine-protein kinase pim-1	0	4	5	9
Fibroblast growth factor receptor 1	0	1	3	4
Myosin light chain kinase, smooth muscle	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	2	3	5
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	3	4
Gamma-aminobutyric acid receptor subunit beta-1	30	4	0	34
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Platelet-derived growth factor receptor alpha	0	1	3	4
Tyrosine-protein kinase Fer	0	0	3	3
cAMP-dependent protein kinase catalytic subunit alpha	0	4	3	7
Vascular endothelial growth factor receptor 1	0	1	2	3
Gamma-aminobutyric acid receptor subunit delta	30	4	0	34
Gamma-aminobutyric acid receptor subunit gamma-2	30	4	1	35
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	4	3	7
Gamma-aminobutyric acid receptor subunit alpha-5	30	4	0	34
Gamma-aminobutyric acid receptor subunit alpha-3	30	4	0	34
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	3	3
Fibroblast growth factor receptor 2	0	0	2	2
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	3	3	6
Tyrosine-protein kinase JAK1	0	1	3	4
Gamma-aminobutyric acid receptor subunit gamma-1	30	4	0	34
Gamma-aminobutyric acid receptor subunit alpha-2	30	4	0	34
Protein kinase C eta type	0	2	2	4
Cyclin-dependent kinase 2	0	2	4	6
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	3	3
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Gamma-aminobutyric acid receptor subunit alpha-4	30	4	0	34
Gamma-aminobutyric acid receptor subunit gamma-3	30	4	0	34
Mitogen-activated protein kinase 1	0	0	3	3
Ephrin type-A receptor 2	0	0	3	3
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	0	3	3
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	3	3
Gamma-aminobutyric acid receptor subunit alpha-6	30	4	0	34
Wee1-like protein kinase	0	0	3	3
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	2	3	5
RAC-beta serine/threonine-protein kinase	0	0	3	3
Dual specificity protein kinase TTK	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	1	2	3
Vascular endothelial growth factor receptor 2	0	3	2	5
Dual specificity mitogen-activated protein kinase kinase 2	0	0	3	3
Receptor-type tyrosine-protein kinase FLT3	0	1	3	4
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	2	4	6
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	1	3	4
Tyrosine-protein kinase CSK	0	1	3	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	2	2
Tyrosine-protein kinase Tec	0	0	3	3
Tyrosine-protein kinase TXK	0	0	2	2
Tyrosine-protein kinase ABL2	0	1	3	4
Tyrosine-protein kinase FRK	0	0	3	3
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	2	4	6
Mitogen-activated protein kinase 8	0	0	3	3
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	1	3	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Histamine H2 receptor	20	5	2	29
Casein kinase I isoform delta	0	0	3	3
MAP kinase-activated protein kinase 2	0	0	3	3
Cyclin-dependent kinase 8	0	0	2	2
Casein kinase I isoform epsilon	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	1	3	4
Glycogen synthase kinase-3 beta	0	3	3	6
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Tyrosine-protein kinase Blk	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	3	3
Cytoplasmic tyrosine-protein kinase BMX	0	1	2	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek2	0	1	3	4
Tyrosine-protein kinase JAK3	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	3	3	6
Death-associated protein kinase 1	0	3	2	5
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Mitogen-activated protein kinase 12	0	0	2	2
Mitogen-activated protein kinase 10	0	2	3	5
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	2
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	0	3	3
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	3	3
Serine/threonine-protein kinase SIK1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	30	5	1	36
Gamma-aminobutyric acid receptor subunit beta-3	30	4	0	34
Gamma-aminobutyric acid receptor subunit beta-2	30	4	1	35
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	4	2	6
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Cyclin-dependent kinase 3	0	0	3	3
Cyclin-dependent-like kinase 5	0	1	3	4
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
Protein kinase C epsilon type	0	2	2	4
Dual specificity mitogen-activated protein kinase kinase 1	0	1	3	4
Angiopoietin-1 receptor	0	0	3	3
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Protein kinase C theta type	0	2	3	5
Activin receptor type-1	0	0	3	3
Focal adhesion kinase 1	0	1	3	4
Protein kinase C delta type	0	2	3	5
Tyrosine-protein kinase BTK	0	0	3	3
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	0	3	3
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	0	2	2
Tyrosine-protein kinase Mer	0	0	3	3
Serine/threonine-protein kinase 4	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	3	3
Serine/threonine-protein kinase PAK 1	0	1	2	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
cGMP-dependent protein kinase 2	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
cGMP-dependent protein kinase 1	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Serine/threonine-protein kinase D1	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	3	3
Ribosomal protein S6 kinase alpha-1	0	0	3	3
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	3	3
Mitogen-activated protein kinase 11	0	0	3	3
Serine/threonine-protein kinase STK11	0	0	3	3
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	1	3	4
Serine/threonine-protein kinase N2	0	1	3	4
Mitogen-activated protein kinase 14	0	5	3	8
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	0	3	3
AP2-associated protein kinase 1	0	0	3	3
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	3	3
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	1	3	4
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	3	3
Myosin-IIIb	0	0	2	2
GABA theta subunit	30	4	0	34
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Aurora kinase B	0	1	3	4
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Serine/threonine-protein kinase D2	0	0	3	3
Serine/threonine-protein kinase DCLK3	0	0	2	2
Gamma-aminobutyric acid receptor subunit epsilon	30	4	0	34
NUAK family SNF1-like kinase 2	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	3	3
Tyrosine-protein kinase Srms	0	0	2	2
Serine/threonine-protein kinase PLK3	0	2	2	4
Dual specificity protein kinase CLK4	0	0	3	3
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	1	2	3
Casein kinase I isoform gamma-1	0	0	3	3
Serine/threonine-protein kinase PAK 6	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
BMP-2-inducible protein kinase	0	0	3	3
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	3	3
eIF-2-alpha kinase GCN2	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
ALK tyrosine kinase receptor	0	1	2	3
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Chain A, TRYPSIN	0	1	0	1
Chain A, TRYPSIN	0	1	0	1
Chain A, TRYPSIN	0	1	0	1
Chain A, TRYPSIN	0	1	0	1
Chain A, TRYPSIN	0	1	0	1
Chain A, TRYPSIN	0	1	0	1
Membrane primary amine oxidase	0	0	0	1
Cationic trypsin	0	3	0	3
Amine oxidase [flavin-containing] A	0	12	0	12
Membrane primary amine oxidase	0	0	0	1
Chain A, Avidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain B, Avidin	0	0	1	1
estrogen nuclear receptor alpha	79	0	0	79
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
glucocorticoid receptor [Homo sapiens]	54	0	0	54
estrogen-related nuclear receptor alpha	55	0	0	55
thyroid hormone receptor beta isoform 2	49	0	0	49
lamin isoform A-delta10	51	0	0	51
Chain A, ATP-DEPENDENT DNA HELICASE Q1	13	0	0	13
Microtubule-associated protein tau	34	0	0	34
vitamin D3 receptor isoform VDRA	23	0	0	23
thyroid hormone receptor beta isoform a	19	0	0	19
DNA polymerase kappa isoform 1	29	0	0	29
Chain A, Ferritin light chain	22	0	0	22
endonuclease IV	6	0	0	6
15-lipoxygenase, partial	13	0	0	13
WRN	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
NFKB1 protein, partial	11	0	0	11
Thrombopoietin	6	0	0	6
apical membrane antigen 1, AMA1	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	18	0	0	18
nonstructural protein 1	6	0	0	6
NPYLR7B	0	0	1	1
glucocerebrosidase	17	0	0	17
arylsulfatase A	24	0	0	24
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	11	0	0	11
Bloom syndrome protein isoform 1	26	0	0	26
peripheral myelin protein 22 isoform 1	14	0	0	14
cellular tumor antigen p53 isoform a	12	0	0	12
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
cytochrome P450 2C9 precursor	14	0	0	14
chromobox protein homolog 1	32	0	0	32
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	10	0	0	10
potassium voltage-gated channel subfamily H member 2 isoform d	17	0	0	17
importin subunit beta-1 isoform 1	5	0	0	5
flap endonuclease 1	20	0	0	20
snurportin-1	5	0	0	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	14	0	0	14
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	8	0	0	8
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	23	0	0	23
M-phase phosphoprotein 8	15	0	0	15
muscarinic acetylcholine receptor M1	20	0	0	20
pyruvate kinase PKM isoform b	3	0	0	3
Ornithine decarboxylase	3	0	0	3
Glutamate receptor ionotropic, NMDA 1	0	10	1	16
Glutamate receptor ionotropic, NMDA 2A	0	9	1	15
Glutamate receptor ionotropic, NMDA 2B	0	9	1	15
Glutamate receptor ionotropic, NMDA 2C	0	9	1	15
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
large T antigen	0	3	0	3
AR protein	73	0	0	73
peroxisome proliferator activated receptor gamma	36	0	0	36
ATP-binding cassette sub-family C member 3	0	43	0	43
Multidrug resistance-associated protein 4	0	43	0	48
Bile salt export pump	0	63	0	63
Cellular tumor antigen p53	50	0	0	50
Thromboxane-A synthase	0	4	0	4
Prostaglandin E2 receptor EP3 subtype	0	3	0	3
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin E2 receptor EP1 subtype	0	3	0	3
Prostacyclin receptor	0	5	3	8
Nuclear receptor subfamily 4 group A member 2	0	0	3	3
Solute carrier organic anion transporter family member 2A1	0	0	0	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Canalicular multispecific organic anion transporter 1	0	42	0	42
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR	0	1	0	1
acid sphingomyelinase	6	0	0	6
acetylcholinesterase	25	0	0	25
thyroid stimulating hormone receptor	30	0	0	30
alpha-galactosidase	8	0	0	8
lysosomal alpha-glucosidase preproprotein	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	47	0	0	47
Membrane primary amine oxidase	0	2	0	2
Solute carrier family 22 member 1	0	10	0	13
Prothrombin	0	3	2	5
Coagulation factor X	0	1	0	1
Plasminogen	0	1	0	1
Urokinase-type plasminogen activator	0	4	0	4
Tissue-type plasminogen activator	0	3	0	3
Coagulation factor XI	0	1	0	1
Plasma kallikrein	0	1	0	7
Vitamin K-dependent protein C	0	1	0	1
Urokinase-type plasminogen activator	0	3	0	3
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Sodium/hydrogen exchanger 1	0	3	0	3
Sodium/hydrogen exchanger 3	0	2	0	2
Adenosine receptor A2a	0	7	3	12
Trypsin-3	0	2	0	2
Amiloride-sensitive sodium channel subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Sodium/hydrogen exchanger 2	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	20	0	21
Sodium channel protein type 5 subunit alpha	0	4	0	4
Sodium/hydrogen exchanger 5	0	2	0	2
Solute carrier family 22 member 1	0	6	0	7
Solute carrier family 22 member 2	0	5	0	6
Acid-sensing ion channel 3	0	1	0	1
Sodium/hydrogen exchanger	0	1	0	1
dopamine D1 receptor	7	0	0	7
D(1A) dopamine receptor	9	0	0	9
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
Cystathionine gamma-lyase	0	1	0	1
Cystathionine beta-synthase	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	33	0	0	33
cytochrome P450 2D6	24	0	0	24
atrial natriuretic peptide receptor 2 precursor	6	0	0	6
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
5-hydroxytryptamine receptor 4	0	9	1	10
Albumin	0	0	1	1
Aldo-keto reductase family 1 member B1	0	13	0	13
Muscarinic acetylcholine receptor M2	0	14	4	20
Muscarinic acetylcholine receptor M4	0	10	3	14
Muscarinic acetylcholine receptor M1	0	6	2	10
Muscarinic acetylcholine receptor M3	0	6	2	9
Muscarinic acetylcholine receptor M4	0	5	1	7
5-hydroxytryptamine receptor 2C	0	5	1	7
Muscarinic acetylcholine receptor M5	0	6	1	8
Muscarinic acetylcholine receptor M5	0	10	3	14
Alpha-2A adrenergic receptor	0	11	3	14
Muscarinic acetylcholine receptor M2	0	6	1	8
Muscarinic acetylcholine receptor M1	0	12	3	17
Angiotensin-converting enzyme	0	4	0	4
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	6	2	8
Alpha-2B adrenergic receptor	0	12	2	14
Alpha-2C adrenergic receptor	0	12	2	14
5-hydroxytryptamine receptor 1A	0	10	1	11
Muscarinic acetylcholine receptor M3	0	12	3	16
D(1A) dopamine receptor	0	7	0	7
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	3
Sodium-dependent noradrenaline transporter	0	14	3	17
Histamine H2 receptor	0	9	2	11
Alpha-1D adrenergic receptor	0	12	1	14
5-hydroxytryptamine receptor 2A	0	10	0	10
5-hydroxytryptamine receptor 2C	0	11	0	11
5-hydroxytryptamine receptor 1B	0	8	1	9
5-hydroxytryptamine receptor 1D	0	3	1	4
5-hydroxytryptamine receptor 1F	0	3	1	4
5-hydroxytryptamine receptor 2B	0	4	1	5
5-hydroxytryptamine receptor 6	0	3	1	4
Histamine H1 receptor	0	7	1	8
Sodium-dependent serotonin transporter	0	15	2	17
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	3	1	4
5-hydroxytryptamine receptor 5B	0	3	1	4
Histamine H1 receptor	0	12	2	14
D(3) dopamine receptor	0	8	1	9
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	4	0	4
UDP-glucuronosyltransferase 1A3	0	0	0	3
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 2B	0	11	0	11
Alpha-1A adrenergic receptor	0	19	3	22
5-hydroxytryptamine receptor 6	0	5	0	5
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Sodium-dependent dopamine transporter	0	15	1	16
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	3	2	5
5-hydroxytryptamine receptor 4	0	3	1	4
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	9	0	9
5-hydroxytryptamine receptor 3B	0	3	1	4
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	4	2	6
Sodium channel protein type 10 subunit alpha	0	2	0	2
Fatty-acid amide hydrolase 1	0	6	0	6
Fatty-acid amide hydrolase 1	0	1	0	2
Potassium channel subfamily K member 3	0	4	0	4
Fatty acid-binding protein, liver	0	4	0	4
Glutamate receptor 1	1	1	3	5
Glutamate receptor 2	28	1	3	32
Glutamate receptor 3	1	1	3	5
Glutamate receptor 4	1	1	3	5
Cannabinoid receptor 1	0	5	3	8
Cannabinoid receptor 1	0	10	2	16
Cannabinoid receptor 2	0	10	4	18
Cannabinoid receptor 1	0	3	0	3
Cannabinoid receptor 2	0	2	2	4
Fatty-acid amide hydrolase 1	0	3	0	4
Fatty acid-binding protein 5	0	0	2	2
Corticotropin-releasing factor receptor 2	0	3	0	3
Lanosterol 14-alpha demethylase	0	4	0	4
Potassium channel subfamily K member 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	3	4	9
Cannabinoid receptor 2	0	4	0	4
Transient receptor potential cation channel subfamily V member 2	0	4	2	6
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	2
PAX8	0	0	0	2
Hsf1 protein	0	0	2	3
Smad3	11	0	0	11
hepatitis C virus polyprotein	1	0	0	1
heat shock protein 90	0	0	1	1
caspase recruitment domain family, member 15	0	2	0	2
Spike glycoprotein	0	1	5	6
Replicase polyprotein 1ab	0	2	5	7
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	2	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Transmembrane protease serine 2	0	1	5	6
Bcl-2-like protein 11	0	0	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	3	5	8
Replicase polyprotein 1a	0	1	5	6
Replicase polyprotein 1ab	0	1	5	6
Replicase polyprotein 1ab	0	9	6	15
Replicase polyprotein 1ab	0	11	6	17
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Alpha-synuclein	9	4	1	14
Spike glycoprotein	25	1	5	31
TAR DNA-binding protein 43	16	0	0	16
Angiotensin-converting enzyme 2	0	1	5	6
Beta lactamase (plasmid)	0	3	0	3
hypoxia-inducible factor 1 alpha subunit	17	0	0	17
RAR-related orphan receptor gamma	49	0	0	49
GALC protein	5	0	0	5
GLI family zinc finger 3	48	0	0	48
caspase 7, apoptosis-related cysteine protease	11	0	0	11
estrogen receptor 2 (ER beta)	29	0	0	29
nuclear receptor subfamily 1, group I, member 3	39	0	0	39
progesterone receptor	34	0	0	34
retinoic acid nuclear receptor alpha variant 1	49	0	0	49
retinoid X nuclear receptor alpha	43	0	0	43
farnesoid X nuclear receptor	31	0	0	31
pregnane X nuclear receptor	47	0	0	47
G	21	0	0	21
peroxisome proliferator-activated receptor delta	32	0	0	32
vitamin D (1,25- dihydroxyvitamin D3) receptor	34	0	0	34
caspase-3	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	35	0	0	35
thyroid stimulating hormone receptor	24	0	0	24
v-jun sarcoma virus 17 oncogene homolog (avian)	29	0	0	29
Histone H2A.x	25	0	0	25
heat shock protein beta-1	21	0	0	21
Voltage-dependent calcium channel gamma-2 subunit	27	0	0	27
Interferon beta	30	0	0	30
HLA class I histocompatibility antigen, B alpha chain	21	0	0	21
Cytochrome P450 3A4	0	14	2	20
Substance-P receptor	0	7	2	9
Neuromedin-K receptor	0	5	3	8
Substance-P receptor	0	1	0	1
Inositol hexakisphosphate kinase 1	21	0	0	21
cytochrome P450 2C9, partial	21	0	0	21
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, Beta-lactamase	15	0	0	15
thioredoxin glutathione reductase	15	0	0	15
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
nuclear receptor ROR-gamma isoform 1	21	0	0	21
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
caspase-1 isoform alpha precursor	4	0	0	4
Prostaglandin G/H synthase 1	0	6	0	8
Trypsin	0	3	0	4
Coagulation factor VII	0	3	0	3
60 kDa chaperonin	0	6	0	6
60 kDa heat shock protein, mitochondrial	0	6	0	6
Aromatase	0	6	0	6
Tissue factor	0	4	0	4
Fatty acid-binding protein, adipocyte	0	3	1	4
Prostaglandin G/H synthase 2	0	10	4	16
10 kDa heat shock protein, mitochondrial	0	6	0	6
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	1	0	6
Prostaglandin G/H synthase 2	0	7	0	8
Fatty acid-binding protein 5	0	2	0	2
Thiosulfate sulfurtransferase	0	6	0	6
60 kDa chaperonin	0	7	0	7
10 kDa chaperonin	0	7	0	7
Solute carrier organic anion transporter family member 1B3	0	6	0	7
Cytosolic phospholipase A2 gamma	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	7	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
Polyphenol oxidase 2	0	2	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
SMAD family member 2	25	0	0	25
PPM1D protein	10	0	0	10
SMAD family member 3	25	0	0	25
aryl hydrocarbon receptor	30	0	0	30
histone deacetylase 9 isoform 3	9	0	0	9
Bone morphogenetic protein receptor type-1B	0	0	2	2
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	2	3
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Mitogen-activated protein kinase 13	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	3	2	5
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	2	2	4
Cyclin-dependent kinase 1	0	3	2	5
Glycogen phosphorylase, liver form	0	1	2	3
Adenine phosphoribosyltransferase	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	2	2
Cytochrome P450 2D6	0	9	1	10
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	1	3	4
DNA topoisomerase 2-alpha	0	1	2	6
Cyclin-dependent kinase 4	0	3	2	5
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	2	2	4
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	2	4
Protein kinase C alpha type	0	3	2	5
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	3	2	5
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Deoxycytidine kinase	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
G protein-coupled receptor kinase 4	0	0	1	1
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	2	2	4
Exosome RNA helicase MTR4	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Serine/threonine-protein kinase mTOR	0	2	1	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
G protein-coupled receptor kinase 6	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	1	4
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	2	2
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 6	0	1	2	3
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Protein kinase C zeta type	0	2	2	4
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	4	2	6
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	2	3
Cyclin-dependent kinase 13	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Rhodopsin kinase GRK1	0	0	1	1
Myosin light chain kinase 3	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
ATPase family AAA domain-containing protein 5	22	0	0	22
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	2	2
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
dCTP pyrophosphatase 1	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
Serine/threonine-protein kinase PLK2	0	2	1	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Phosphatidylinositol 4-kinase beta	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	1	2	3
Septin-9	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
interleukin 8	10	0	0	10
Fumarate hydratase	11	0	0	11
polyprotein	11	0	0	11
P53	2	0	0	2
activating transcription factor 6	20	0	0	20
hemoglobin subunit beta	3	0	0	3
peripheral myelin protein 22	29	0	0	29
muscleblind-like protein 1 isoform 1	14	0	0	14
Bile salt export pump	0	5	0	5
Nuclear receptor ROR-gamma	16	0	0	16
Protein-arginine deiminase type-4	0	6	0	6
Chain A, Protein kinase C, iota	0	1	0	1
G2/mitotic-specific cyclin-B2	0	2	0	2
G1/S-specific cyclin-E2	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Protein kinase C gamma type	0	2	0	2
G2/mitotic-specific cyclin-B1	0	3	0	3
Insulin receptor	0	1	0	1
Lethal factor	0	2	0	2
Glycogen synthase kinase-3 beta	0	3	0	3
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	0	1	0	1
G1/S-specific cyclin-D1	0	3	0	3
G1/S-specific cyclin-E1	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
MO15-related protein kinase Pfmrk	0	2	0	2
Peroxisome proliferator-activated receptor alpha	1	1	0	2
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
G2/mitotic-specific cyclin-B3	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	2	0	2
Serine/threonine-protein kinase LMTK3	0	1	0	1
Angiotensin-converting enzyme	0	1	0	2
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	4	4
neuropeptide S receptor isoform A	13	0	0	13
Solute carrier family 22 member 6	0	6	0	7
Carbonic anhydrase 12	0	4	0	11
Carbonic anhydrase 1	0	16	0	26
Carbonic anhydrase 2	0	17	1	29
Carbonic anhydrase 3	0	4	0	10
Carbonic anhydrase 4	0	13	0	21
Carbonic anhydrase 6	0	7	0	14
Carbonic anhydrase 5A, mitochondrial	0	10	0	17
Carbonic anhydrase 7	0	6	0	13
Solute carrier family 12 member 2	0	1	0	1
Carbonic anhydrase 9	0	11	0	18
Carbonic anhydrase 13	0	4	0	10
Carbonic anhydrase 14	0	4	0	11
Carbonic anhydrase 5B, mitochondrial	0	8	0	15
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	3	4
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
DNA polymerase beta	16	0	0	16
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	2	0	2
Cholinesterase	0	5	0	5
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	7	0	7
Acetylcholinesterase	0	7	0	7
Adenosine receptor A1	1	9	0	16
Amine oxidase [flavin-containing] B	0	10	0	10
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	2	0	4
Adenosine receptor A2b	0	3	1	6
Adenosine receptor A1	0	6	2	12
Adenosine receptor A2a	0	7	1	16
Vasopressin V2 receptor	0	0	0	2
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	1	2
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	3	5
Endochitinase B1	0	2	0	2
Muscarinic acetylcholine receptor	0	2	1	4
Phosphodiesterase	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	7
Guanine deaminase	0	1	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	7	0	9
Androgen receptor	0	6	3	10
Vitamin D3 receptor	0	2	3	8
Cytochrome P450 2C9	0	12	0	13
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	1	1	2
Cytochrome P450 2C19	0	4	0	5
Kappa-type opioid receptor	0	7	2	9
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Acetylcholinesterase	0	4	0	4
L-lactate dehydrogenase A chain	0	2	0	2
Cytochrome P450 1A1	0	5	1	6
Cytochrome P450 2C11	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	2	5
Cytochrome P450 2A6	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Cytochrome P450 3A5	0	2	0	3
Cytochrome P450 3A7	0	1	0	1
Caspase-1	0	1	1	3
Mu-type opioid receptor	0	9	5	17
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Delta-type opioid receptor	0	10	4	17
Kappa-type opioid receptor	0	8	6	17
Cholinesterase	0	3	0	3
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Cytochrome P450 1B1	0	5	1	6
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	3	4
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Transient receptor potential cation channel subfamily V member 4	0	1	2	3
G-protein coupled receptor 55	0	1	2	3
Diacylglycerol lipase-alpha	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
Lysine-specific histone demethylase 1A	0	3	0	3
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	6	0	7
Prostaglandin G/H synthase 1	0	8	0	9
D(2) dopamine receptor	0	3	2	5
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
thyrotropin-releasing hormone receptor	5	0	0	5
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Delta-type opioid receptor	0	8	3	15
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	1	2
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	4
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Carbonic anhydrase 4	0	2	0	5
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	3	0	3
Prostaglandin G/H synthase 1	0	6	1	8
Sucrase-isomaltase, intestinal	0	1	0	1
Xanthine dehydrogenase/oxidase	0	4	0	4
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Beta-secretase 1	0	6	0	6
Carbonic anhydrase 3	0	2	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	3	0	3
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
glp-1 receptor, partial	13	0	0	13
pregnane X receptor	8	0	0	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	19	0	0	19
Caspase-7	2	0	0	2
interferon gamma precursor	0	0	0	3
prostaglandin E2 receptor EP2 subtype	1	0	0	2
caspase-3	2	0	0	2
Prostaglandin E synthase	0	4	0	4
Histone deacetylase 3	0	5	0	5
Prostaglandin G/H synthase 2	0	3	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	3	0	5
Quinolone resistance protein NorA	0	1	0	1
Beta-3 adrenergic receptor	0	4	1	5
Alpha-1B adrenergic receptor	0	14	1	15
Calpain-2 catalytic subunit	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	3	0	3
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Sodium-dependent serotonin transporter	0	6	2	8
Delta-type opioid receptor	0	8	4	13
Mu-type opioid receptor	0	12	4	19
Bifunctional epoxide hydrolase 2	0	6	0	6
Prostaglandin G/H synthase 2	0	4	0	4
Carbonic anhydrase	0	7	0	12
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	7
Histone deacetylase 4	0	5	0	5
Ras-related protein Rab-2A	0	0	1	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	10	1	11
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Histone deacetylase 1	0	6	0	6
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	1	0	7
Carbonic anhydrase	0	3	0	9
Carbonic anhydrase	0	2	0	8
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase	0	1	0	7
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	5	0	5
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	6	0	6
Polyamine deacetylase HDAC10	0	5	0	5
Histone deacetylase 11	0	5	0	5
Carbonic anhydrase 15	0	3	0	8
Histone deacetylase 8	0	6	0	6
P2Y purinoceptor 12	0	2	1	3
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	5	0	5
Histone deacetylase 5	0	5	0	5
Multidrug and toxin extrusion protein 1	0	8	0	8
Histamine H4 receptor	0	5	2	7
1,3-beta-D-glucan synthase catalytic subunit	0	1	0	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Rap guanine nucleotide exchange factor 3	8	0	0	8
Amyloid-beta precursor protein	0	6	0	7
Aldo-keto reductase family 1 member B1	0	8	0	8
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	5	1	6
Lactoperoxidase	0	1	0	3
Integrase	0	5	0	5
Glycine receptor subunit alpha-1	0	0	3	3
Thymidine kinase	0	2	0	3
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	2
Solute carrier family 22 member 6	0	5	0	8
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	3	0	6
Solute carrier family 22 member 2	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
ATP-dependent translocase ABCB1	0	8	2	11
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	5	0	5
Histamine H1 receptor	0	1	4	6
Potassium-transporting ATPase subunit beta	0	1	0	1
Cytochrome P450 2J2	0	7	0	7
Aldehyde oxidase	0	2	0	2
Multidrug and toxin extrusion protein 2	0	2	0	2
Solute carrier family 22 member 8	0	4	0	8
Solute carrier family 22 member 11	0	2	0	5
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	5
DNA gyrase subunit B	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	2
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Beta-1 adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	2	2
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	5	0	6
Alpha-1A adrenergic receptor	0	2	2	4
D	0	2	0	2
D(3) dopamine receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	7	0	7
Alpha-2C adrenergic receptor	0	7	0	7
Alpha-2A adrenergic receptor	0	7	0	7
Alpha-1D adrenergic receptor	0	10	1	11
D(1B) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	0	0	2
D(4) dopamine receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	5	3	9
Alpha-1B adrenergic receptor	0	5	2	8
Alpha-2C adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Nischarin	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	2	0	3
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Glucocorticoid receptor	0	16	3	25
Sex hormone-binding globulin	0	0	5	5
Glycine receptor subunit alpha-1	0	16	0	16
Corticosteroid-binding globulin	0	3	0	3
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	1	2	3
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Nrf2	3	0	0	3
alkaline phosphatase, intestinal	0	1	0	1
PINK1	2	0	0	2
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	7	0	0	7
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
tumor susceptibility gene 101 protein	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Integrin beta-3	6	0	0	6
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	3	0	3
Integrin alpha-IIb	6	0	0	6
Glutathione S-transferase P	0	2	0	2
Microtubule-associated protein tau	0	5	1	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Heme oxygenase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Proteasome subunit beta type-5	0	5	0	5
17-beta-hydroxysteroid dehydrogenase type 2	0	3	0	3
Caspase-7	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	4	0	4
Histone acetyltransferase p300	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	2	3
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Deoxycytidine kinase	0	0	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Phenylethanolamine N-methyltransferase	0	1	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Sodium-dependent dopamine transporter	0	3	1	4
Amine oxidase [flavin-containing] B	0	3	0	3
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Cereblon isoform 4	0	4	0	4
Choline O-acetyltransferase	0	2	0	2
Protein cereblon	0	4	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	2	4
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	3	1	4
Prostaglandin E2 receptor EP2 subtype	0	2	2	4
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	8	1	14
Glutamate receptor ionotropic, NMDA 3B	0	8	1	14
Glutamate receptor ionotropic, NMDA 3A	0	8	1	14
Alpha-1A adrenergic receptor	0	1	0	1
Interstitial collagenase	0	2	1	3
Beta-2 adrenergic receptor	0	4	1	5
Histamine H3 receptor	0	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Transient receptor potential cation channel subfamily A member 1	0	1	1	3
N-arachidonyl glycine receptor	0	0	1	1
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoglyceride lipase	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, PROTEIN KINASE CK2, ALPHA SUBUNIT	0	1	0	1
Chain A, Casein kinase II, alpha chain	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	0	1	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	0	1	1
DNA polymerase III, partial	2	0	0	2
hypothetical protein, conserved	5	0	0	5
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
serine/threonine-protein kinase PLK1	4	0	0	4
Protein tyrosine phosphatase type IVA 3	0	1	0	1
Transthyretin	0	2	1	3
Estrogen receptor	0	11	4	17
Neutrophil elastase	0	4	0	4
Accessory gene regulator protein A	0	1	0	1
Spike glycoprotein	0	1	0	1
Genome polyprotein	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
Proteasome subunit beta type-2	0	1	0	1
Casein kinase II subunit beta	0	4	0	4
Tissue alpha-L-fucosidase	0	2	0	2
Genome polyprotein	0	1	0	1
Casein kinase II subunit alpha 3	0	3	0	3
Estrogen receptor beta	0	9	2	11
P2Y purinoceptor 12	0	2	1	3
Sialidase-2	0	4	0	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Opioid receptor, delta 1b	0	2	0	2
Opioid receptor homologue	0	2	0	2
Proenkephalin-B	0	0	1	1
Kappa-type opioid receptor	0	4	2	8
Kappa-type opioid receptor	0	6	4	11
Mu-type opioid receptor	0	5	2	10
Mu-type opioid receptor	0	2	0	2
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	3	1	4
galactokinase	2	0	0	2
POsterior Segregation	0	0	2	2
Telomerase reverse transcriptase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	4	0	6
Polymerase acidic protein	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Matrilysin	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Alpha-amylase 1A	0	2	0	2
Apoptosis regulator Bcl-2	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
CPG DNA methylase	0	1	0	1
Phosphoglycerate mutase 1	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
Dipeptidyl peptidase 4	0	3	0	3
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
BH3-interacting domain death agonist	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Bcl-2-related protein A1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Reverse transcriptase/RNaseH	0	2	0	2
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	4	0	4
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	3	0	3
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	5	5
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
Albumin	0	1	4	5
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
eyes absent homolog 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Androgen receptor	0	7	0	7
UDP-glucuronosyltransferase 2B7	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	2
Luciferin 4-monooxygenase	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	0	0	1
Tyrosine-protein phosphatase 1	0	1	0	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	4
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Estrogen receptor	0	1	2	3
Progesterone receptor	0	5	2	8
Steroid hormone receptor ERR1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Bile acid receptor	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	2
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, Estrogen receptor 1 (alpha)	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
BRCA1	2	0	0	2
Neuraminidase	0	3	0	3
Alpha-mannosidase	0	1	0	1
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Maltase-glucoamylase, intestinal	0	3	0	3
Steroid hormone receptor ERR2	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Sialidase	0	2	0	2
Tyrosinase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	2	2
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Substance-P receptor	0	5	0	5
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Acetylcholinesterase	0	1	0	1
Alpha-glucosidase MAL32	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Quinone oxidoreductase	0	0	0	1
Oxysterols receptor LXR-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Oxysterols receptor LXR-alpha	0	1	0	1
Substance-K receptor	0	3	0	3
Prenyltransferase homolog	0	0	0	1
Carboxylic ester hydrolase	0	1	0	2
Dipeptidyl peptidase 3	0	2	0	2
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	3	0	3
Asc-type amino acid transporter 1	0	2	0	2
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	6
Amino acid transporter	0	3	0	3
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	6
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	0	2	0	2
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	0	2	0	2
Chain B, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Chain A, Rho-associated protein kinase 1	0	2	0	2
Membrane-associated progesterone receptor component 1	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	2	0	2
Poly [ADP-ribose] polymerase 1	0	1	0	1
C-C motif chemokine 2	0	2	0	2
Cyclin-dependent kinase 10	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Rab-like protein 3	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	4	0	4
Prostacyclin receptor	0	1	1	2
Prostaglandin D2 receptor	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Cytochrome P450 2C8	0	2	0	3
Snq2p	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Major prion protein	0	0	1	1
Sphingomyelin phosphodiesterase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	2	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Multidrug resistance-associated protein 1	0	2	0	3
Aldo-keto reductase family 1 member C3	0	4	0	4
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Aldo-keto reductase family 1 member C1	0	2	0	2
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	3	0	5
Cysteinyl leukotriene receptor 2	0	1	2	3
Cysteinyl leukotriene receptor 1	0	4	3	7
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, heart	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Dual specificity protein phosphatase 3	0	1	0	1
Free fatty acid receptor 4	0	0	1	1
Mineralocorticoid receptor	0	3	1	4
Androgen receptor	0	0	1	1
ClpP	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	3	0	3
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	1	2
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Carboxylic ester hydrolase	0	1	0	1
Secreted chorismate mutase	0	1	0	1
Transient receptor potential cation channel subfamily M member 8	0	1	2	4
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	3	4
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
phosphoglycerate kinase	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Substance-K receptor	0	8	0	9
Leukotriene C4 synthase	0	1	0	1
Cysteinyl leukotriene receptor 1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	2	2
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	2	2
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
voltage-dependent T-type calcium channel subunit alpha-1H isoform a	0	0	1	1
Beta-1 adrenergic receptor	0	2	0	2
Beta-2 adrenergic receptor	0	1	0	1
Neuromedin-K receptor	0	0	3	3
Substance-K receptor	0	1	3	4
Substance-K receptor	0	3	0	3
Substance-K receptor	0	3	0	3
Neuromedin-K receptor	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Estrogen receptor beta	0	0	2	2
Nociceptin receptor	0	1	3	4
Nociceptin receptor	0	2	2	5
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Microphthalmia-associated transcription factor	0	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	2	1	3
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	3	0	3
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	2	0	2
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	3
Phospholipase A-2-activating protein	0	3	0	3
Beta-1 adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Peroxisomal sarcosine oxidase	0	0	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Glutamate 5-kinase	0	0	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
hexokinase	0	2	0	2
B2 bradykinin receptor	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Stromelysin-1	0	3	0	3
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Calmodulin-1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Urease subunit alpha	0	3	0	3
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
C-C chemokine receptor type 4	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Urease subunit beta	0	3	0	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
NADPH oxidase 4	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
Carbonic anhydrase	0	2	0	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Substance-P receptor	0	2	0	2
Growth hormone secretagogue receptor type 1	0	0	1	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 2	0	1	0	1
Cathepsin B	0	1	0	1
P2Y purinoceptor 2	0	1	1	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 2	0	1	1	2
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
NAD-dependent protein deacetylase HST2	0	1	0	1
P2X purinoceptor 3	0	0	1	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	1	0	1
DNA primase	0	2	0	2
P2Y purinoceptor 6	0	1	0	1
Dual specificity protein phosphatase 5	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 8	0	1	0	1
RmtA	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 3	0	1	0	1
P2Y purinoceptor 11	0	1	1	2
P2X purinoceptor 7	0	0	1	1
Protein arginine N-methyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Vif	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	4
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L5	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-3	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	0	0	1	1
MSH	0	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	0	1	0	1
Chain I, cAMP-dependent protein kinase inhibitor alpha	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

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Research

Studies (645)

Protein Targets (2,103)

Cystitis, Interstitial

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (645)

Drugs Studied (293)

Protein Targets (2,103)