Deficiency, Factor II

Synonym
Factor II Deficiency
Deficiency, Factor II
Hypoprothrombinemia
Hypoprothrombinemias
Prothrombin Deficiency

Excerpt	Reference
"Hypoprothrombinemia is a relatively uncommon event in the hospitalized patient."	( Adelman, MH; Grasela, TH; Schentag, JJ; Welage, LS, 1987)
"We believe hypoprothrombinemia is a more common complication of cefoperazone therapy than is generally acknowledged, and is preventable."	( Green, D; Mueller, RJ; Phair, JP, 1987)
"Hypoprothrombinemia is an uncommon hereditary coagulation defect characterized by low levels of biologically active prothrombin."	( Augustine, J; Rappaport, EF; Schwartz, E; Shalmon, L; Surrey, S; Tamary, H, 1997)
"Prothrombin deficiency is a rare (1:200 000) autosomal recessive disorder caused by diverse mutations in prothrombin gene."	( Baidya, S; Chandy, M; Jayandharan, G; Nair, SC; Shaji, RV; Srivastava, A; Viswabandya, A, 2005)

Excerpt	Reference
"Hypoprothrombinemia has occurred frequently with cephalosporins that possess a methylthiotetrazole substitution (cefamandole, moxalactam, and cefoperazone)."	( Ballard, JO; Sattler, FR; Weitekamp, MR, 1986)

Excerpt	Reference
"Prophylactic vitamin K can prevent hypoprothrombinemia in patients treated with IL-2."	( Birchfield, GR; Girodias, KW; Rodgers, GM; Samlowski, WE; Ward, JH, 1992)
"Some third generation agents can cause hypoprothrombinemia if not administered with vitamin K, and disulfiram-like reactions occur with some agents because of the presence of a thiomethyl tetruzole moiety affixed to the cephem nucleus."	( Neu, HC, 1990)
"Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed."	( Bossaert, LL; Conraads, VM; Demey, HE; Heytens, LG, 1988)
"A man with lupus anticoagulant and a prothrombin deficiency was studied before and after cessation of treatment with phenytoin."	( Alperin, JB; Harrison, RL; Kumar, D, 1987)
"If serious hemorrhage occurs, hypoprothrombinemia associated with methylthiotetrazole-substituted cephalosporins should be treated with fresh frozen plasma."	( Ballard, JO; Sattler, FR; Weitekamp, MR, 1986)
"We believe hypoprothrombinemia is a more common complication of cefoperazone therapy than is generally acknowledged, and is preventable."	( Green, D; Mueller, RJ; Phair, JP, 1987)
"We present a case of warfarin-induced hypoprothrombinemia treated with aqueous vitamin K1, which resulted in the appearance of eczematous vitamin K1 hypersensitivity."	( English, JC; Keough, GC; Meffert, JJ, 1998)
"We diagnosed the patient with hypoprothrombinemia because of vitamin K deficiency caused by markedly elevated protein levels induced by vitamin K absence or antagonist-II on day 6 of CMZ administration."	( Akizuki, H; Haba, Y; Hashiguchi, N; Naito, T, 2022)
"Lupus anti-coagulant hypoprothrombinemia syndrome (LAHPS) is a rare condition that can be difficult to treat."	( Carroll, WL; Chumsky, J; Hillier, K; Kahn, PJ; Pierce, KA, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	473 (82.69)	23.3326
1990's	55 (9.62)	12.5806
2000's	23 (4.02)	18.1394
2010's	15 (2.62)	28.8240
2020's	6 (1.05)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
carbon monoxide	low	1	0
choline	low	1	0
coumarin	low	28	0
salicylic acid	low	4	0
2-aminoadipic acid	low	1	0
aminocaproic acid	low	2	0
creatine	low	1	0
glycine	low	1	0
hydrogen carbonate	low	1	0
dalteparin	low	1	0
nitrites	low	1	0
thymine	low	1	0
phenytoin	low	2	0
acetaminophen	low	1	0
amobarbital	low	1	0
amsacrine	low	1	0
antipyrine	low	2	0
aspirin	low	12	0
azathioprine	low	2	0
aztreonam	low	1	0
2,5-di-tert-butylhydroquinone	low	1	0
busulfan	low	1	0
caffeine	low	1	0
celecoxib	low	1	0
chloral hydrate	low	2	0
chlorpromazine	low	1	0
chlorpropamide	low	1	0
cimetidine	low	1	0
ciprofloxacin	low	1	0
cisapride	low	1	0
clofibrate	medium	2	1
cyproheptadine	low	1	0
diphenhydramine	low	2	0
disulfiram	low	3	0
fluorouracil	low	1	0
fluoxetine	medium	1	1
gemfibrozil	low	1	0
gentamicin	medium	1	1
gossypol	low	1	0
guaifenesin	low	2	0
guanethidine	low	1	0
hexobarbital	low	1	0
hydroxychloroquine	low	1	0
indomethacin	low	1	0
iproniazid	low	1	0
isoniazid	low	1	0
isoxsuprine	low	1	0
vitamin k 3	low	6	0
mephenesin	low	1	0
meprobamate	low	1	0
mitotane	low	1	0
papaverine	low	1	0
phenacetin	low	2	0
phenindione	low	13	0
phenobarbital	low	8	0
phenylbutazone	low	6	0
primidone	low	1	0
proadifen	low	2	0
promethazine	low	1	0
rofecoxib	low	1	0
secobarbital	low	1	0
sulfadimethoxine	low	1	0
sulfamethizole	low	1	0
sulfamethoxazole	low	1	0
sulfaquinoxaline	low	2	0
sulfasalazine	low	1	0
sulfathiazole	low	2	0
sulfinpyrazone	medium	2	1
sulfisoxazole	low	1	0
sulfobromophthalein	low	4	0
triclosan	low	1	0
trimeprazine	low	1	0
trimethoprim	low	1	0
prednisolone	low	3	0
reserpine	low	3	0
thyroxine	low	1	0
spironolactone	low	1	0
prednisone	low	16	0
alanine	low	1	0
serine	low	1	0
chloramphenicol	low	3	0
lysine	low	3	0
cyanides	low	1	0
sucrose	low	1	0
ethinyl estradiol	low	1	0
tubocurarine	low	1	0
adenosine diphosphate	medium	3	1
kanamycin a	low	1	0
edetic acid	low	5	0
tyrosine	low	1	0
methylene blue	low	1	0
aniline	low	1	0
methionine	low	1	0
phenylalanine	low	1	0
colchicine	low	1	0
oxacillin	low	1	0
cycloheximide	low	3	0
chloroform	low	1	0
norethynodrel	low	2	0
ampicillin	low	1	0
mannitol	low	1	0
histidine	low	1	0
valine	low	1	0
threonine	low	1	0
mestranol	low	2	0
methaqualone	low	1	0
tryptophan	low	2	0
arginine	low	8	0
trichloroacetic acid	low	1	0
methylprednisolone	low	2	0
tolonium chloride	low	1	0
ergotamine	low	1	0
dextrothyroxine	low	1	0
nafcillin	low	2	0
ephedrine	low	1	0
menadiol	low	1	0
dixanthogen	low	1	0
cyclocumarol	low	1	0
hesperidin	low	1	0
erythromycin	low	1	0
2,4,6-tri-tert-butylphenol	low	1	0
ethylestrenol	low	1	0
thorium dioxide	low	1	0
vancomycin	medium	2	1
d-alpha tocopherol	low	2	0
dicloxacillin	low	1	0
dithiothreitol	low	1	0
tranylcypromine	low	1	0
streptomycin	low	2	0
barium sulfate	low	4	0
tricalcium phosphate	low	1	0
chlorine	low	2	0
trolamine salicylate	low	3	0
ornidazole	low	1	0
danazol	low	2	0
iodine	low	1	0
triamcinolone	low	1	0
4-methoxyamphetamine	low	1	0
glutamic acid	low	4	0
cefazolin	medium	8	2
amoxicillin	low	1	0
tobramycin	medium	2	2
etoposide	low	1	0
ticarcillin	medium	1	1
ticrynafen	low	1	0
methyldopa	low	1	0
cefmetazole	low	4	0
cefonicid	low	2	0
cefoperazone	medium	13	2
moxalactam	medium	25	4
cefotetan	medium	7	1
lovastatin	low	2	0
sulofenur	medium	1	1
metaperiodate	low	1	0
cephalosporin c	medium	36	1
fibrinogen	low	26	0
arginyl-glycyl-aspartic acid	low	1	0
dansylarginine n-(3-ethyl-1,5-pentanediyl)amide	low	2	0
1,3-indandione	low	1	0
h-d-phe-pip-arg-pna	low	1	0
sulbactam	low	1	0
xylose	low	2	0
beta-lactams	low	4	0
phytol	low	2	0
ic 831423	low	1	0
arginine-4-nitroanilide	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
fibrin	low	7	0
glucosamine	low	1	0
quinidine	low	3	0
cefoxitin	medium	1	1
retinol	low	3	0
clindamycin	medium	2	2
zithromax	low	1	0
cefamandole	medium	12	1
melphalan	low	4	0
isomethyleugenol	low	1	0
flavin-adenine dinucleotide	low	1	0
mezlocillin	medium	1	1
propylthiouracil	low	7	0
mercaptopurine	low	1	0
thiouracil	low	3	0
methimazole	low	1	0
2-methyl-1,3,4-thiadiazole-5-thiol	low	3	0
1-n-methyl-5-thiotetrazole	medium	13	1
thiourea	low	1	0
D-fructopyranose	low	1	0
digoxin	low	1	0
nadp	low	1	0
naphthoquinones	low	26	0
ubiquinone q2	low	1	0
bilirubin	low	4	0
dinoprostone	low	1	0
vitamin k semiquinone radical	medium	193	7
vitamin k1 oxide	low	3	0
esculin	low	1	0
coenzyme q10	low	1	0
indomethacin farnesil	low	1	0
menatetrenone	low	1	0
menaquinone 6	low	2	0
vitamin k 1	medium	68	2
cysteine	low	3	0
heroin	low	1	0
cefotaxime	medium	8	1
selenium	low	1	0
oxalates	low	1	0
hesperidin methylchalcone	low	1	0
nitrofurantoin	low	1	0
calcimycin	low	1	0
benzoyl-ile-glu-gly-arg-p-nitroanilide	low	1	0
acid phosphatase	low	1	0
nad	low	2	0
fibrinopeptide b	low	1	0
ristocetin	low	1	0
cellulose	low	2	0
sodium salicylate	low	3	0
ubiquinone	low	1	0
ro13-9904	medium	2	1
sodium ethylxanthate	low	1	0
fibrinopeptide a	low	2	0
piperidines	low	1	0
natriuretic peptide, brain	low	1	0
ascorbic acid	low	5	0
tetracycline	low	2	0
salicylates	low	9	0
dicumarol	medium	53	1
acenocoumarol	low	4	0
difenacoum	low	1	0
warfarin	medium	114	5
bromfenacoum	low	1	0
phenprocoumon	low	4	0
ethyl biscoumacetate	medium	11	1
kaolinite	low	5	0
agar	low	1	0
hirudin	low	1	0
vitamin b 12	low	3	0
thromboplastin	low	51	0
muramidase	low	1	0
guanine	low	1	0
folic acid	low	1	0
rifampin	low	2	0
cholestyramine resin	low	3	0

Protein Targets (1,690)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Luciferase	29	0	0	29
GLI family zinc finger 3	79	0	0	79
progesterone receptor	46	0	0	46
v-jun sarcoma virus 17 oncogene homolog (avian)	41	0	0	41
Coagulation factor XII	0	1	0	1
Cholinesterase	0	4	0	4
Acetylcholinesterase	0	9	0	9
Liver carboxylesterase 1	0	1	0	2
hypoxia-inducible factor 1 alpha subunit	27	0	0	27
AR protein	87	0	0	87
nuclear receptor subfamily 1, group I, member 3	58	0	0	58
retinoic acid nuclear receptor alpha variant 1	71	0	0	71
retinoid X nuclear receptor alpha	66	0	0	66
farnesoid X nuclear receptor	48	0	0	48
pregnane X nuclear receptor	60	0	0	60
estrogen nuclear receptor alpha	107	0	0	107
peroxisome proliferator-activated receptor delta	42	0	0	42
peroxisome proliferator activated receptor gamma	51	0	0	51
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	42	0	0	42
thyroid stimulating hormone receptor	35	0	0	35
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	26	0	0	26
Histone H2A.x	32	0	0	32
thyroid hormone receptor beta isoform 2	62	0	0	62
heat shock protein beta-1	32	0	0	32
nuclear factor erythroid 2-related factor 2 isoform 1	70	0	0	70
Cellular tumor antigen p53	60	0	0	60
Chain A, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	23	0	0	23
Chain A, 2-oxoglutarate Oxygenase	30	0	0	30
alternatively spliced Trp4	0	0	1	1
15-lipoxygenase, partial	12	0	0	12
RAR-related orphan receptor gamma	63	0	0	63
USP1 protein, partial	39	0	0	39
TDP1 protein	68	0	0	68
Microtubule-associated protein tau	36	0	0	36
aldehyde dehydrogenase 1 family, member A1	49	0	0	49
estrogen receptor 2 (ER beta)	39	0	0	39
glucocorticoid receptor [Homo sapiens]	70	0	0	70
estrogen-related nuclear receptor alpha	80	0	0	80
vitamin D (1,25- dihydroxyvitamin D3) receptor	46	0	0	46
euchromatic histone-lysine N-methyltransferase 2	62	0	0	62
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
activating transcription factor 6	32	0	0	32
thyrotropin-releasing hormone receptor	7	0	0	7
vitamin D3 receptor isoform VDRA	28	0	0	28
survival motor neuron protein isoform d	23	0	0	23
lethal factor (plasmid)	25	0	0	25
Voltage-dependent calcium channel gamma-2 subunit	37	0	0	37
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Glutamate receptor 2	37	3	1	41
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	1	0	1
5-hydroxytryptamine receptor 2C	0	6	1	7
5-hydroxytryptamine receptor 2A	0	11	1	12
5-hydroxytryptamine receptor 1A	0	16	1	17
5-hydroxytryptamine receptor 1B	0	11	1	12
5-hydroxytryptamine receptor 1D	0	3	1	4
5-hydroxytryptamine receptor 1F	0	3	1	4
5-hydroxytryptamine receptor 2B	0	7	1	8
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	21	3	24
Sodium-dependent serotonin transporter	0	5	1	6
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 4	0	0	2	3
5-hydroxytryptamine receptor 3B	0	2	1	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	33	0	0	33
G	42	0	0	42
chromobox protein homolog 1	45	0	0	45
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	17	0	0	17
geminin	68	0	0	68
muscleblind-like protein 1 isoform 1	18	0	0	18
Interferon beta	54	0	0	54
HLA class I histocompatibility antigen, B alpha chain	42	0	0	42
Guanine nucleotide-binding protein G	6	0	0	6
Inositol hexakisphosphate kinase 1	42	0	0	42
cytochrome P450 2C9, partial	42	0	0	42
ATAD5 protein, partial	24	0	0	24
GLS protein	27	0	0	27
Smad3	23	0	0	23
thyroid stimulating hormone receptor	40	0	0	40
EWS/FLI fusion protein	32	0	0	32
aryl hydrocarbon receptor	33	0	0	33
peripheral myelin protein 22	31	0	0	31
cytochrome P450 3A4 isoform 1	38	0	0	38
Gamma-aminobutyric acid receptor subunit pi	38	2	0	40
ATP-binding cassette sub-family C member 3	0	58	0	58
Multidrug resistance-associated protein 4	0	58	0	61
Solute carrier family 22 member 6	0	15	0	15
Carbonic anhydrase 12	0	4	0	9
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	15	0	15
Bile salt export pump	0	84	0	84
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	19	0	27
Carbonic anhydrase 2	0	20	1	29
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	1	1	3
Cytochrome P450 1A2	0	6	2	10
Prostaglandin G/H synthase 1	0	9	0	10
Carbonic anhydrase 3	0	4	0	8
Cytochrome P450 3A4	0	20	2	23
Cytochrome P450 2D6	0	14	2	16
Cytochrome P450 2C9	0	26	1	27
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Gamma-aminobutyric acid receptor subunit beta-1	38	2	0	40
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	38	2	0	40
Gamma-aminobutyric acid receptor subunit gamma-2	38	2	0	40
UDP-glucuronosyltransferase 1-6	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	38	2	0	40
Gamma-aminobutyric acid receptor subunit alpha-3	38	2	0	40
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	5	0	8
Carbonic anhydrase 4	0	9	0	13
Prostaglandin G/H synthase 1	0	11	0	12
Carbonic anhydrase 6	0	4	0	8
Gamma-aminobutyric acid receptor subunit gamma-1	38	2	0	40
Gamma-aminobutyric acid receptor subunit alpha-2	38	2	0	40
Gamma-aminobutyric acid receptor subunit alpha-4	38	2	0	40
Gamma-aminobutyric acid receptor subunit gamma-3	38	2	0	40
Gamma-aminobutyric acid receptor subunit alpha-6	38	2	0	40
Carbonic anhydrase 5A, mitochondrial	0	5	0	9
Prostaglandin G/H synthase 2	0	13	2	17
Carbonic anhydrase 7	0	4	0	8
Nuclear receptor ROR-gamma	19	2	2	23
Cytochrome P450 2J2	0	17	0	17
Gamma-aminobutyric acid receptor subunit alpha-1	38	5	0	43
Gamma-aminobutyric acid receptor subunit beta-3	38	2	0	40
Gamma-aminobutyric acid receptor subunit beta-2	38	2	0	40
Carbonic anhydrase 9	0	7	1	13
GABA theta subunit	38	2	0	40
Canalicular multispecific organic anion transporter 1	0	57	0	58
Carbonic anhydrase 15	0	8	0	12
Carbonic anhydrase 13	0	3	0	6
Gamma-aminobutyric acid receptor subunit epsilon	38	2	0	40
Carbonic anhydrase 14	0	4	0	8
Carbonic anhydrase 5B, mitochondrial	0	4	0	8
toxin B	0	0	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	48	0	0	48
nuclear factor erythroid 2-related factor 2 isoform 2	22	0	0	22
importin subunit beta-1 isoform 1	8	0	0	8
snurportin-1	8	0	0	8
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
lamin isoform A-delta10	61	0	0	61
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	1	4
Xanthine dehydrogenase/oxidase	0	2	0	2
TAR DNA-binding protein 43	17	0	0	17
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	23	0	0	23
Ataxin-2	32	0	0	32
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	23	0	0	23
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	1	1	2
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	2	0	2
Mu-type opioid receptor	0	10	1	11
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	8	1	9
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	11	0	0	11
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	2	1	3
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	28	0	0	28
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	3
Glutamate receptor ionotropic, NMDA 1	0	6	2	13
Proton-coupled amino acid transporter 1	0	5	0	5
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	4
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	16	0	0	16
Chain A, Apolipoprotein	0	0	1	1
nonstructural protein 1	9	0	0	9
arylsulfatase A	13	0	0	13
D(1A) dopamine receptor	10	0	0	10
thyroid hormone receptor beta isoform a	25	0	0	25
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	12	0	0	12
histone acetyltransferase KAT2A isoform 1	21	0	0	21
Rap guanine nucleotide exchange factor 3	15	0	0	15
Plasminogen	0	2	1	3
thioredoxin glutathione reductase	23	0	0	23
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	1	4
Chain A, Beta-lactamase	20	0	0	20
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
Beta-lactamase	0	1	0	5
apical membrane antigen 1, AMA1	9	0	0	9
Beta-lactamase	0	0	0	2
DNA polymerase eta isoform 1	10	0	0	10
DNA polymerase iota isoform a (long)	28	0	0	28
urokinase-type plasminogen activator precursor	13	0	0	13
plasminogen precursor	13	0	0	13
urokinase plasminogen activator surface receptor precursor	13	0	0	13
DNA polymerase kappa isoform 1	20	0	0	20
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase SHV-1	0	1	0	4
Beta-lactamase	0	1	0	4
Kappa-type opioid receptor	0	0	0	3
Solute carrier family 15 member 1	0	12	0	12
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	7	0	7
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	8	0	8
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	17	0	0	17
Beta-lactamase	0	1	0	4
acid sphingomyelinase	4	0	0	4
Beta-lactamase	0	2	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	0	3
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	1	0	4
Metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	2	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	18	0	0	18
DNA polymerase beta	10	0	0	10
60 kDa heat shock protein, mitochondrial	0	6	0	6
Beta-lactamase OXA-7	0	0	0	4
Spike glycoprotein	27	4	5	36
10 kDa heat shock protein, mitochondrial	0	6	0	6
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	4
Thiosulfate sulfurtransferase	0	6	0	6
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	7	0	7
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	7	0	7
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	4
Histamine H3 receptor	0	0	0	4
Beta-lactamase class B VIM-2	0	0	0	5
Beta-lactamase VIM-1	0	1	0	3
ATP-dependent phosphofructokinase	30	0	0	30
Chain A, HADH2 protein	21	0	0	21
Chain B, HADH2 protein	21	0	0	21
thioredoxin reductase	34	0	0	34
Fumarate hydratase	21	0	0	21
PPM1D protein	17	0	0	17
Thrombopoietin	8	0	0	8
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	14	0	0	14
polyprotein	21	0	0	21
putative alpha-glucosidase	1	0	0	1
alpha-galactosidase	5	0	0	5
cellular tumor antigen p53 isoform a	15	0	0	15
cytochrome P450 2C9 precursor	20	0	0	20
flap endonuclease 1	18	0	0	18
ras-related protein Rab-9A	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
caspase-1 isoform alpha precursor	5	0	0	5
muscarinic acetylcholine receptor M1	22	0	0	22
Solute carrier family 22 member 1	0	8	0	11
Integrin beta-3	10	2	1	13
Integrin alpha-IIb	10	2	1	13
DNA topoisomerase 2-alpha	0	3	2	16
Histamine H2 receptor	25	2	1	30
D(1A) dopamine receptor	7	0	0	7
5-hydroxytryptamine receptor 7	0	6	0	6
Caspase-7	5	0	0	5
Aldehyde oxidase 1	0	3	0	3
DNA topoisomerase 2-beta	0	2	2	11
Aldehyde oxidase	0	7	0	7
Potassium voltage-gated channel subfamily H member 2	0	23	0	24
Aldehyde oxidase 1	0	5	0	5
Steroid C26-monooxygenase	0	0	1	1
Cytochrome P450 130	0	0	1	1
Cytochrome P450 130	0	0	1	1
67.9K protein	17	0	0	17
Nicotinate phosphoribosyltransferase	0	6	0	6
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
phosphopantetheinyl transferase	35	0	0	35
NFKB1 protein, partial	8	0	0	8
cytochrome P450 2C19 precursor	15	0	0	15
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	2
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	4
Cationic amino acid transporter 3	0	2	0	2
Integrin beta-1	0	1	0	1
Integrin alpha-V	0	1	0	1
Integrin alpha-5	0	1	0	1
Integrin beta-5	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	23	0	0	23
IDH1	21	0	0	21
lethal(3)malignant brain tumor-like protein 1 isoform I	6	0	0	6
Polyphenol oxidase 2	0	6	0	9
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	4	0	5
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	20	1	21
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
interleukin 8	23	0	0	23
hypothetical protein, conserved	4	0	0	4
cytochrome P450 2D6	33	0	0	33
glucocerebrosidase	8	0	0	8
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Bloom syndrome protein isoform 1	15	0	0	15
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	5
Prostaglandin G/H synthase 2	0	4	0	5
Epidermal growth factor receptor	0	5	0	5
Fatty acid-binding protein, liver	0	4	1	5
Myeloperoxidase	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	3	0	3
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	6	0	10
Adenosine receptor A2a	0	5	0	10
Substance-P receptor	0	5	0	6
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	7	0	7
Rho-associated protein kinase 2	0	2	0	2
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	12	1	13
Sigma non-opioid intracellular receptor 1	0	1	1	2
SMAD family member 2	23	0	0	23
SMAD family member 3	23	0	0	23
P53	2	0	0	2
peripheral myelin protein 22 isoform 1	12	0	0	12
hemoglobin subunit beta	5	0	0	5
M-phase phosphoprotein 8	15	0	0	15
Protein-arginine deiminase type-4	0	8	0	8
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain B, Odorant-binding Protein	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	14	0	0	14
histone deacetylase 9 isoform 3	9	0	0	9
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	3	0	3
Hormone-sensitive lipase	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	16	0	18
Solute carrier organic anion transporter family member 1B1	0	15	0	18
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
Matrix metalloproteinase-9	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
nuclear receptor ROR-gamma isoform 1	22	0	0	22
Potassium channel subfamily K member 2	0	2	1	3
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	9	5	14
Adenosine receptor A3	0	13	0	13
Replicase polyprotein 1ab	0	11	5	16
Amine oxidase [flavin-containing] A	0	8	0	9
Amine oxidase [flavin-containing] B	0	6	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	4	1	6
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	3	1	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	2	0	2
Serine/threonine-protein kinase ATR	0	2	0	2
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	4
Guanine deaminase	0	1	0	2
endonuclease IV	8	0	0	8
glp-1 receptor, partial	20	0	0	20
ClpP	1	0	0	1
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
TSHR protein	2	0	0	2
Parkin	7	0	0	7
LacZ protein (plasmid)	0	0	2	2
XBP1	0	1	0	1
serine-protein kinase ATM isoform a	5	0	0	5
lysosomal alpha-glucosidase preproprotein	7	0	0	7
hexokinase-4 isoform 1	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
type-1 angiotensin II receptor	0	2	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	24	0	0	24
glucokinase regulatory protein	3	0	0	3
huntingtin isoform 2	10	0	0	10
mitogen-activated protein kinase 1	14	0	0	14
serine/threonine-protein kinase PLK1	4	0	0	4
apelin receptor	0	2	0	2
heat shock protein HSP 90-alpha isoform 2	0	1	0	5
DNA damage-inducible transcript 3 protein	0	1	0	1
Vpr	7	0	0	7
streptokinase A precursor	0	0	5	5
neuropeptide S receptor isoform A	9	0	0	9
Amyloid-beta precursor protein	3	5	0	8
Alpha-synuclein	7	7	0	14
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	4
Solute carrier family 22 member 6	0	9	0	10
Solute carrier family 22 member 7	0	3	0	6
Solute carrier family 22 member 8	0	9	0	12
Solute carrier family 22 member 11	0	5	0	7
Solute carrier family 22 member 8	0	6	0	6
Solute carrier family 22 member 7	0	3	0	5
Solute carrier family 22 member 8	0	6	0	8
Insulin-degrading enzyme	0	1	0	1
Glutathione reductase, mitochondrial	0	7	0	9
Glutathione peroxidase 1	0	1	0	1
Microsomal glutathione S-transferase 1	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	1	0	2
Albumin	0	3	7	10
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
bromodomain adjacent to zinc finger domain 2B	17	0	0	17
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
DNA dC->dU-editing enzyme APOBEC-3A isoform a	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
pregnane X receptor	19	0	0	19
caspase 7, apoptosis-related cysteine protease	15	0	0	15
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
caspase-3	15	0	0	15
Caspase-7	11	0	0	11
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	2
caspase-3	11	0	0	11
Prostaglandin E synthase	0	2	0	2
Histone deacetylase 3	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	3	0	3
Procathepsin L	0	6	5	11
Aldo-keto reductase family 1 member B1	0	27	0	27
Neuronal acetylcholine receptor subunit alpha-4	2	3	0	5
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Quinolone resistance protein NorA	0	2	0	3
Neuronal acetylcholine receptor subunit beta-2	2	3	0	5
Beta-3 adrenergic receptor	0	5	0	5
Alpha-1B adrenergic receptor	0	20	0	20
Calpain-2 catalytic subunit	0	2	0	2
D(1A) dopamine receptor	0	15	0	16
Prostaglandin G/H synthase 1	0	3	0	3
Sodium-dependent noradrenaline transporter	0	26	2	28
Cruzipain	0	3	0	3
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	2
Bifunctional epoxide hydrolase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	5	0	6
Carbonic anhydrase	0	5	0	9
Alpha-1A adrenergic receptor	0	20	0	20
Carbonic anhydrase	0	1	0	5
Histone deacetylase 4	0	1	0	1
D(2) dopamine receptor	0	8	0	9
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	16	1	17
Prostaglandin G/H synthase 2	0	3	0	4
Histone deacetylase 1	0	2	0	2
Mitogen-activated protein kinase 14	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	5	0	5
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase	0	1	0	5
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	4
Cyclooxygenase-2	0	2	0	2
Histone deacetylase 7	0	1	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
50S ribosomal protein L36 2	0	4	1	5
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	4	5	9
Replicase polyprotein 1ab	0	4	6	10
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	4	5	9
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	3	3
Histidine-rich protein PFHRP-II	0	2	0	3
Muscarinic acetylcholine receptor M2	0	14	0	14
Muscarinic acetylcholine receptor M4	0	10	0	10
Muscarinic acetylcholine receptor M5	0	12	0	12
Alpha-2A adrenergic receptor	0	21	0	21
Replicase polyprotein 1a	0	4	5	9
Replicase polyprotein 1ab	0	4	5	9
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	12	0	12
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	15	0	15
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	14	0	14
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	2	0	2
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	4	5	9
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	2
Adenylate cyclase type 1	0	2	0	2
cytochrome P450 2D6 isoform 1	11	0	0	11
atrial natriuretic peptide receptor 2 precursor	8	0	0	8
Proteasome subunit alpha type-7	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 4	0	14	2	16
Albumin	0	0	3	3
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	3	0	3
ATP-dependent translocase ABCB1	0	17	1	23
Muscarinic acetylcholine receptor M1	0	3	1	4
Muscarinic acetylcholine receptor M3	0	3	1	4
Muscarinic acetylcholine receptor M4	0	3	1	4
5-hydroxytryptamine receptor 1A	0	2	0	2
Muscarinic acetylcholine receptor M5	0	3	1	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	4	1	5
Muscarinic acetylcholine receptor M2	0	3	1	4
Angiotensin-converting enzyme	0	10	0	10
D(2) dopamine receptor	0	12	0	13
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	5	0	5
D(3) dopamine receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	7	0	7
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	6	0	6
D(4) dopamine receptor	0	4	0	5
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	7	0	7
UDP-glucuronosyltransferase 1A4	0	3	0	5
Alpha-2A adrenergic receptor	0	7	0	7
Alpha-1D adrenergic receptor	0	9	0	9
Sodium-dependent dopamine transporter	0	7	0	7
Histamine H2 receptor	0	8	0	8
Alpha-1D adrenergic receptor	0	12	0	12
D(1B) dopamine receptor	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	17	0	17
5-hydroxytryptamine receptor 2C	0	14	0	14
Trypanothione reductase	0	7	0	9
D(4) dopamine receptor	0	3	0	3
Histamine H1 receptor	0	1	2	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	3	0	3
Histamine H1 receptor	0	8	1	9
D(3) dopamine receptor	0	14	0	15
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	2	0	3
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
5-hydroxytryptamine receptor 2B	0	18	0	18
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 6	0	16	0	16
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	2	3
Glutamate receptor ionotropic, NMDA 2A	0	5	2	12
Glutamate receptor ionotropic, NMDA 2B	0	5	2	12
Glutamate receptor ionotropic, NMDA 2C	0	5	2	12
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Sodium channel protein type 5 subunit alpha	0	5	0	5
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	5	2	12
Nuclear receptor subfamily 3 group C member 3	0	10	0	10
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	5	2	12
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	5	2	12
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	1	0	1
transcriptional regulator ERG isoform 3	4	0	0	4
Lanosterol 14-alpha demethylase	0	6	0	6
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	4	0	7
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	7	0	9
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	6	0	7
ATP-dependent translocase ABCB1	0	9	0	9
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	9	0	9
Potassium-transporting ATPase subunit beta	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Multidrug and toxin extrusion protein 1	0	9	0	9
Histamine H4 receptor	0	2	0	2
Solute carrier family 22 member 4	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	3	0	5
DNA gyrase subunit B	0	3	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	7	1	8
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	4	0	4
DNA gyrase subunit A	0	4	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	4	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	5	0	5
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Beta-2 adrenergic receptor	0	3	0	3
Beta-1 adrenergic receptor	0	3	0	3
Dipeptidyl peptidase 4	0	3	0	3
Insulin receptor	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	1	2
Neutral alpha-glucosidase AB	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Heparanase	0	0	2	2
GALC protein	2	0	0	2
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	2	0	2	4
PAX8	0	0	0	2
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	5
Tubulin beta-4A chain	0	2	2	5
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	3	0	3
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	2	0	2
Similar to alpha-tubulin isoform 1	0	2	0	2
CREB-binding protein	2	0	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
dopamine D1 receptor	3	0	0	3
Glucocorticoid receptor	0	16	3	24
Sex hormone-binding globulin	0	0	3	3
Glycine receptor subunit alpha-1	0	16	0	16
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	16	0	16
Glycine receptor subunit alpha-2	0	16	0	16
Glycine receptor subunit alpha-3	0	16	0	16
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
glycogen synthase kinase-3 alpha	0	0	0	1
Exportin-1	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	3
Cytochrome P450 2A6	0	2	0	3
Aldo-keto reductase family 1 member B1	0	5	0	6
UDP-glucuronosyltransferase 2B7	0	3	0	3
Amine oxidase [flavin-containing] B	0	3	0	3
Cytochrome P450 2A5	0	0	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	2	0	2
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	3	0	3
Quinone oxidoreductase	0	0	0	1
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	4	1	5
Zn finger protein	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
RPL19A	0	0	1	1
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	3	1	4
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
D(2) dopamine receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Transporter	0	3	0	3
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Estrogen receptor	0	12	2	14
Androgen receptor	0	18	0	19
Transthyretin	0	3	2	6
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
NAD	0	1	0	1
NAD	0	2	0	5
Mitogen-activated protein kinase 1	0	3	0	3
ATP phosphoribosyltransferase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
G-protein coupled receptor 35	0	1	1	2
STAT3, partial	0	1	0	1
tumor necrosis factor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	3	0	5
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
pyruvate kinase	2	0	0	2
beta-2 adrenergic receptor	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	4	0	0	4
runt-related transcription factor 1 isoform AML1b	1	0	0	1
perilipin-5	0	2	0	2
perilipin-1	0	2	0	2
core-binding factor subunit beta isoform 2	1	0	0	1
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Ornithine decarboxylase	1	0	0	2
Fructose-1,6-bisphosphatase 1	0	1	0	1
C-X-C chemokine receptor type 2	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
Caspase-1	1	5	0	7
C-C chemokine receptor type 2	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Monoglyceride lipase	0	1	0	1
Gasdermin-D	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Thromboxane-A synthase	0	3	0	3
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
60 kDa chaperonin	0	3	0	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Macrophage migration inhibitory factor	0	3	0	3
Taste receptor type 2 member 16	0	0	0	1
Cytochrome P450 2B6	0	2	1	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Estrogen receptor beta	0	4	2	6
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Protease	0	5	1	6
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	1	2
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	2	0	3
DNA topoisomerase 2	0	0	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	2	0	2
DNA topoisomerase 2-alpha	0	0	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Thymidylate synthase	0	2	0	2
Aromatase	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Cytochrome P450 2C8	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	1	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	2	0	3
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	5
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	7	0	8
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Mcl-1	0	1	0	1
Estrogen receptor 1	0	2	0	2
PINK1	3	0	0	3
galactokinase	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	1	0	0	1
Prolyl endopeptidase	0	1	0	1
L-lactate dehydrogenase A chain	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
Apoptosis regulator Bcl-2	0	2	1	3
Malate dehydrogenase, cytoplasmic	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
DNA-3-methyladenine glycosylase	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Kinesin-like protein KIF11	0	1	0	1
BH3-interacting domain death agonist	0	1	0	1
Type 1 InsP3 receptor isoform S2	1	0	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Bcl-2-like protein 1	0	2	1	3
L-lactate dehydrogenase	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
L-lactate dehydrogenase B chain	0	1	0	1
L-lactate dehydrogenase	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Histamine H3 receptor	1	0	0	1
phosphoglycerate kinase	3	0	0	3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Neuraminidase	0	3	0	3
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	4	0	5
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Nischarin	0	1	0	1
Substance-K receptor	0	2	0	2
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Genome polyprotein	0	2	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	6	0	6
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	4	2	6
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	5
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	3	0	3
Aldo-keto reductase family 1 member C2	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	2	0	2
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
isocitrate dehydrogenase 1, partial	4	0	0	4
bcl-2-related protein A1	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	1	0	1
Integrin alpha-L	0	1	1	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Vitamin K-dependent gamma-carboxylase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
estrogen receptor beta isoform 1	0	2	0	2
Cystathionine gamma-lyase	0	2	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	2
Glycoprotein hormones alpha chain	2	0	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	3
Microtubule-associated protein tau	0	3	1	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Dihydrofolate reductase	0	5	0	5
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	0	1
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
MecA	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Phospholipase A-2-activating protein	0	2	0	2
fMet-Leu-Phe receptor	0	2	0	2
Gamma-aminobutyric acid	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	4	1	6
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	2	4
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Cholinesterase	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	2	0	2
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Dipeptidyl peptidase 4	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	2	1	3
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	1	1	2
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase TEM	0	2	0	2
Beta-lactamase	0	1	0	2
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	3	0	3
exodeoxyribonuclease V subunit RecC	0	3	0	3
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	2	0	2
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	3	0	3
Chain A, Glutathione S-transferase	0	1	0	1
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Flavin reductase (NADPH)	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	3	0	3
Protein arginine N-methyltransferase 6	0	1	0	1
Multidrug resistance-associated protein 5	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Urease subunit beta	0	1	0	1
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Protein Rev	0	0	1	1
Cytochrome P450 2E1	0	1	0	1
Cytochrome P450 4B1	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Cytochrome P450 2A7	0	1	0	1
Cytochrome P450 3A7	0	1	0	1
Cytochrome P450 2F1	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Cytochrome P450 4F8	0	1	0	1
Cytochrome P450 4A11	0	1	0	1
Cytochrome P450 4F3	0	1	0	1
Cytochrome P450 2A13	0	1	0	1
Cytochrome P450 4A22	0	1	0	1
Vitamin D 25-hydroxylase	0	1	0	1
Cytochrome P450 2U1	0	1	0	1
Cytochrome P450 2W1	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Cytochrome P450 2S1	0	1	0	1
Cytochrome P450 3A43	0	1	0	1
REST corepressor 3	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
Enoyl-ACP reductase II	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Arginase 1	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
glyceraldehyde-3-phosphate dehydrogenase isoform 1	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Dual specificity protein phosphatase 1	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
M-phase inducer phosphatase 2	0	1	0	1
M-phase inducer phosphatase 3	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Receptor-type tyrosine-protein phosphatase eta	0	1	0	1
Platelet-activating factor acetylhydrolase	0	0	0	1
Receptor protein-tyrosine kinase	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Dual specificity protein phosphatase 6	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	0	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Hsf1 protein	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (572)

Protein Targets (1,690)

Deficiency, Factor II

Synonyms(5)

Research Excerpts

Overview

Context

Treatment

Research

Studies (572)

Drugs Studied (278)

Protein Targets (1,690)