Page last updated: 2024-08-05 11:18:36
oxolanes
Any oxacycle having an oxolane (tetrahydrofuran) skeleton.
ChEBI ID: 26912
Members (20)
| Member | Definition | Role |
|---|---|---|
| 1-[1-(1-adamantyl)butyl]-3-(2-oxolanylmethyl)thiourea | 1-[1-(1-adamantyl)butyl]-3-(2-oxolanylmethyl)thiourea | |
| 4-methoxy-2,5-dimethyl-3(2h)-furanone | Mesifurane | |
| alborixin | A polyether antibiotic that is isolated from cultures of a strain of Streptomyces albus. | alborixin |
| astragaloside ii | A triterpenoid saponin that is cycloastragenol glycosylated at positions 3 and 6 by 2-O-acetyl-beta-D-xylosyl and beta-D-glucosyl residues respectively. | astragaloside II |
| aureothin | A C-nitro compound that is (3Z)-3-[(2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ylidene]tetrahydrofuran which is substituted by a 6-methoxy-3,5-dimethyl-4-oxo-4H-pyran-2-yl group at position 5. It is isolated from the soil bacterium, Streptomyces thioluteus and exhibits antitumor, antifungal, and insecticidal activities. | aureothin |
| botryodiplodin | Botryodiplodin | |
| davanone | Davanone | |
| hetacillin | A lignan that consists of tetrahydrofuran substituted by a 3,4-dihydroxyphenyl group at position 2, a hydroxymethyl group at position 3 and a 4-hydroxy-3-methoxybenzyl group at position 4. It has been isolated from Taxus yunnanensis. | taxiresinol |
| isoobtusilactone a | Obtusilactone A | |
| jatrophone | Jatrophone | |
| lariciresinol | A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer). | (+)-lariciresinol |
| lasalocid | A polyether antibiotic used for prevention and treatment of coccidiosis in poultry. | lasalocid |
| liquid crystal polymer | A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines. | bromuconazole |
| manassantin b | A lignan isolated from Saururus cernuus and Saururus chinensis and has been shown to exhibit antineoplastic activity. | manassantin B |
| posaconazole | An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug. | posaconazole |
| scorpions | (E)-dinotefuran; dinotefuran | |
| sq 22536 | A nucleoside analogue that is adenine in which the nitrogen at position 9 has been substituted by a tetrahydrofuran-2-yl group. It is an adenylate cyclase inhibitor. | 9-(tetrahydrofuryl)adenine |
| tetrahydrofuran | A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen. | oxolane |
| tetrahydrofurfuryl alcohol | A primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group. | tetrahydrofurfuryl alcohol |
| tetrahydrofurfuryl methacrylate | Tetrahydrofurfuryl methacrylate |
Research
Studies (3,565)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 535 (15.01) | 18.7374 |
| 1990's | 269 (7.55) | 18.2507 |
| 2000's | 923 (25.89) | 29.6817 |
| 2010's | 1,533 (43.00) | 24.3611 |
| 2020's | 305 (8.56) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 114 (3.09%) | 5.53% |
| Reviews | 223 (6.04%) | 6.00% |
| Case Studies | 361 (9.78%) | 4.05% |
| Observational | 37 (1.00%) | 0.25% |
| Other | 2,958 (80.10%) | 84.16% |