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oxolanes

Any oxacycle having an oxolane (tetrahydrofuran) skeleton.

ChEBI ID: 26912

Members (20)

MemberDefinitionRole
1-[1-(1-adamantyl)butyl]-3-(2-oxolanylmethyl)thiourea1-[1-(1-adamantyl)butyl]-3-(2-oxolanylmethyl)thiourea
4-methoxy-2,5-dimethyl-3(2h)-furanoneMesifurane
alborixinA polyether antibiotic that is isolated from cultures of a strain of Streptomyces albus.alborixin
astragaloside iiA triterpenoid saponin that is cycloastragenol glycosylated at positions 3 and 6 by 2-O-acetyl-beta-D-xylosyl and beta-D-glucosyl residues respectively.astragaloside II
aureothinA C-nitro compound that is (3Z)-3-[(2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ylidene]tetrahydrofuran which is substituted by a 6-methoxy-3,5-dimethyl-4-oxo-4H-pyran-2-yl group at position 5. It is isolated from the soil bacterium, Streptomyces thioluteus and exhibits antitumor, antifungal, and insecticidal activities.aureothin
botryodiplodinBotryodiplodin
davanoneDavanone
hetacillinA lignan that consists of tetrahydrofuran substituted by a 3,4-dihydroxyphenyl group at position 2, a hydroxymethyl group at position 3 and a 4-hydroxy-3-methoxybenzyl group at position 4. It has been isolated from Taxus yunnanensis.taxiresinol
isoobtusilactone aObtusilactone A
jatrophoneJatrophone
lariciresinolA lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer).(+)-lariciresinol
lasalocidA polyether antibiotic used for prevention and treatment of coccidiosis in poultry.lasalocid
liquid crystal polymerA member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines.bromuconazole
manassantin bA lignan isolated from Saururus cernuus and Saururus chinensis and has been shown to exhibit antineoplastic activity.manassantin B
posaconazoleAn N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.posaconazole
scorpions(E)-dinotefuran; dinotefuran
sq 22536A nucleoside analogue that is adenine in which the nitrogen at position 9 has been substituted by a tetrahydrofuran-2-yl group. It is an adenylate cyclase inhibitor.9-(tetrahydrofuryl)adenine
tetrahydrofuranA cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen.oxolane
tetrahydrofurfuryl alcoholA primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group.tetrahydrofurfuryl alcohol
tetrahydrofurfuryl methacrylateTetrahydrofurfuryl methacrylate

Research

Studies (3,565)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990535 (15.01)18.7374
1990's269 (7.55)18.2507
2000's923 (25.89)29.6817
2010's1,533 (43.00)24.3611
2020's305 (8.56)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials114 (3.09%)5.53%
Reviews223 (6.04%)6.00%
Case Studies361 (9.78%)4.05%
Observational37 (1.00%)0.25%
Other2,958 (80.10%)84.16%