Page last updated: 2024-08-05 10:47:06
organic thiophosphate
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ChEBI ID: 37512
Members (61)
| Member | Definition | Role |
|---|---|---|
| acephate | A phosphoramide that is methamidophos in which one of the hydrogens is replaced by an acetyl group. | acephate |
| amifostine anhydrous | An organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. | amifostine |
| azamethiphos | azamethiphos | |
| azinphos ethyl | azinphos-ethyl | |
| azinphosmethyl | A member of the class of benzotriazines that is 1,2,3-benzotriazine substituted by an oxo group at position 4 and a [(dimethoxyphosphorothioyl)sulfanyl]methyl group at position 3. | azinphos-methyl |
| bromophos | Bromofos | |
| butyl phosphorotrithioate | tribufos | |
| cadusafos | cadusafos | |
| chlorpyrifos | An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. | chlorpyrifos |
| chlorpyrifos-methyl | An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. | chlorpyrifos-methyl |
| coumaphos | coumaphos | |
| cyanophos | cyanophos | |
| demeton-s-methyl | demeton-S-methyl | |
| diazinon | A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4. | diazinon |
| dichlofenthion | Dichlofenthion | |
| dimethoate | A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group. | dimethoate |
| dimethoxon | omethoate | |
| disulfoton | An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate. | disulfoton |
| edifenphos | An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid. Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates. | edifenphos |
| ethion | An organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7). | ethion |
| ethoprophos | ethoprophos | |
| famophos | famphur | |
| fenitrothion | An organic thiophosphate that is O,O-dimethyl O-phenyl phosphorothioate substituted by a methyl group at position 3 and a nitro group at position 4. | fenitrothion |
| fensulfothion | fensulfothion | |
| fenthion | An organic thiophosphate that is O,O-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits acaricidal and insecticidal activities. | fenthion |
| fonofos | fonofos | |
| iodofenphos | Iodofenphos | |
| isazophos | Isazofos | |
| malaoxon | A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphoryl)thio group. | diethyl 2-[(dimethoxyphosphoryl)thio]succinate |
| malathion | A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group. | diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate |
| mecarbam | An organic thiophosphate that is O,O-diethyl hydrogen phosphorodithioate in which the hydrogen attached to a sulfur is replaced by a 2-[(ethoxycarbonyl)(methyl)amino]-2-oxoethyl group. | mecarbam |
| methamidophos | An organic thiophosphate resulting from the N-deacylation of the proinsecticide acephate. | methamidophos |
| methidathion | methidathion | |
| methyl parathion | A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4. | parathion-methyl |
| o,o-diethyl dithiophosphate | diethyl dithiophosphate | |
| o,o-diethyl phosphorothionate | An organic thiophosphate that is the diethyl ester of phosphorothioic O,O,O-acid. | O,O-diethyl hydrogen thiophosphate |
| o,o-diisopropyl-s-benzylthiophosphate | An organic thiophosphate that is the S-benzyl O,O-diisopropyl ester of phosphorothioic acid. Used as a rice fungicide to control leaf and ear blast, stem rot and sheath blight. | iprobenfos |
| o,o-dimethyl phosphorothionate | Dimethylthiophosphate | |
| parathion | parathion | |
| phenthoate, (+-)-isomer | An organic thiophosphate that is ethyl mandelate in which the hydroxy group has been replaced by a (dimethoxyphosphorothioyl)sulfanediyl group. | phenthoate |
| phorate | phorate | |
| phosmet | phosmet | |
| pirimiphos methyl | An organic thiophosphate that is O,O-dimethyl O-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2. | pirimiphos-methyl |
| profenofos | profenofos | |
| prothiophos | An organic thiophosphate that is the 2,4-dichlorophenyl ester of O-ethyl S-propyl dithiophosphoric acid. | prothiofos |
| pyraclofos | pyraclofos | |
| pyrazophos | A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A profungicide (by hydrolysis of the thionophosphate group to afford the corresponding 2-hydroxypyrazolopyrimidine fungicide), it is used to control Erysiphe, Helminthosporium and Rhynchospium in cereals. | pyrazophos |
| pyridafenthion | pyridaphenthion | |
| quinalphos | quinalphos | |
| ronnel | Fenchlorphos | |
| s-phosphocysteine | A phosphoamino acid consisting of L-cysteine carrying an S-phospho substituent. | S-phospho-L-cysteine |
| salithion | Salithion | |
| sulfotepp | sulfotep | |
| sulprofos | sulprofos | |
| temefos | An organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group. | temephos |
| terbufos | terbufos | |
| tert-butylbicyclophosphorothionate | tert-Butylbicyclophosphorothionate | |
| thiometon | thiometon | |
| tolclofos-methyl | An organic thiophosphate that is 2,6-dichloro-4-methylphenol in which the hydrogen of the hydroxy group group has been replaced by a dimethoxyphosphorothioyl group. Tolclofos-methyl is a phospholipid biosynthesis inhibitor and fungicide that is used for controlling soil-borne diseases caused by Typhula incarnata, Corticium rolfsii, Typhula ishikariensis, and Rhizoctonia solani. | tolclofos-methyl |
| triazophos | triazophos | |
| vx | A organic thiophosphate that is the ethyl ester of S-{2-[di(propan-2-yl)amino]ethyl} O hydrogen methylphosphonothioate. A toxic nerve agent used in chemical warfare. | VX nerve agent |
Research
Studies (17,250)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4,432 (25.69) | 18.7374 |
| 1990's | 2,185 (12.67) | 18.2507 |
| 2000's | 3,714 (21.53) | 29.6817 |
| 2010's | 4,397 (25.49) | 24.3611 |
| 2020's | 2,522 (14.62) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 404 (1.93%) | 5.53% |
| Reviews | 716 (3.42%) | 6.00% |
| Case Studies | 588 (2.81%) | 4.05% |
| Observational | 34 (0.16%) | 0.25% |
| Other | 19,196 (91.68%) | 84.16% |