Page last updated: 2024-08-05 12:01:47
glycopeptide
Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide.
ChEBI ID: 24396
Members (10)
| Member | Definition | Role |
|---|---|---|
| chloroorienticin b | A glycopeptide that is isolated from Amycolatopsis orientalis. | chloroorienticin B |
| dalbavancin | A semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. | dalbavancin |
| muramyl dipeptide | A glycopeptide that is N-propionyl-L-alanyl-D-alpha-glutamine in which the pro-R hydrogen of the propionyl group has been replaced by the oxygen at position 3 of 2-acetamido-2-deoxy-beta-D-glucopyranose. A peptidoglycan constituent of both Gram-positive and Gram-negative bacteria. | muramyl dipeptide |
| oritavancin | A semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. | oritavancin |
| peplomycin | peplomycin | |
| phleomycin d1 | A glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. | phleomycin D1 |
| ristocetin | A heterodetic cyclic peptide that is produced by species of Amycolatopsis and Nocardia. | ristocetin |
| telavancin | A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria. | telavancin |
| vancomycin | A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. | vancomycin |
| zorbamycin | A glycopeptide antibiotic found in Streptomyces flavoviridis. | zorbamycin |
Research
Studies (18,154)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2,689 (14.81) | 18.7374 |
| 1990's | 3,112 (17.14) | 18.2507 |
| 2000's | 3,808 (20.98) | 29.6817 |
| 2010's | 6,100 (33.60) | 24.3611 |
| 2020's | 2,445 (13.47) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 887 (4.55%) | 5.53% |
| Reviews | 1,687 (8.65%) | 6.00% |
| Case Studies | 2,758 (14.14%) | 4.05% |
| Observational | 218 (1.12%) | 0.25% |
| Other | 13,949 (71.54%) | 84.16% |