Page last updated: 2024-08-05 12:01:47

glycopeptide

Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide.

ChEBI ID: 24396

Members (10)

MemberDefinitionRole
chloroorienticin bA glycopeptide that is isolated from Amycolatopsis orientalis.chloroorienticin B
dalbavancinA semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA.dalbavancin
muramyl dipeptideA glycopeptide that is N-propionyl-L-alanyl-D-alpha-glutamine in which the pro-R hydrogen of the propionyl group has been replaced by the oxygen at position 3 of 2-acetamido-2-deoxy-beta-D-glucopyranose. A peptidoglycan constituent of both Gram-positive and Gram-negative bacteria.muramyl dipeptide
oritavancinA semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA.oritavancin
peplomycinpeplomycin
phleomycin d1A glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe.phleomycin D1
ristocetinA heterodetic cyclic peptide that is produced by species of Amycolatopsis and Nocardia.ristocetin
telavancinA glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria.telavancin
vancomycinA complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.vancomycin
zorbamycinA glycopeptide antibiotic found in Streptomyces flavoviridis.zorbamycin

Research

Studies (18,154)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19902,689 (14.81)18.7374
1990's3,112 (17.14)18.2507
2000's3,808 (20.98)29.6817
2010's6,100 (33.60)24.3611
2020's2,445 (13.47)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials887 (4.55%)5.53%
Reviews1,687 (8.65%)6.00%
Case Studies2,758 (14.14%)4.05%
Observational218 (1.12%)0.25%
Other13,949 (71.54%)84.16%