Excerpt | Reference |
"We conclude that vitamin B12 deficiency is a rare finding in chronic pancreatitis and does not strictly depend on the degree of exocrine pancreatic insufficiency." | ( Büchler, M; Ditschuneit, H; Glasbrenner, B; Kuhn, K; Malfertheiner, P, 1991) |
"In such patients, vitamin B12 deficiency is confirmed by determining serum levels of homocysteine and methylmalonic acid." | ( Clementz, GL; Schade, SG, 1990) |
"Vitamin B12 deficiency is a frequently considered diagnosis for which there is no single, commonly available and accurate test." | ( Feussner, JR; Gale, D; Matchar, DB; Millington, DS; Watson, DJ; Wilkinson, RH, 1987) |
"Once vitamin B 12 deficiency is recognized and diagnosed, it can be easily treated, usually with gratifying results." | ( Crantz, JG, 1985) |
"A vitamin B12 deficiency is unusual in pregnant women who consume a normal, varied diet." | ( Davis, RE, 1985) |
"Folic acid and vitamin B 12 deficiency are less important causes of nutritional anaemia." | ( Lechner, K; Raja, M, 1984) |
"Vitamin B12 deficiency is treatable with monthly injections, large doses of daily oral supplement tablets, or an intranasal gel, which is far better absorbed than comparable oral supplements." | ( Swain, R, 1995) |
"It is possible that vitamin B12 deficiency is more common in pregnant and lactating women and their young children in developing countries than has been recognized previously, primarily because of malabsorption." | ( Allen, LH, 1994) |
"Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe and, contrary to textbook statements, is often due to pernicious anaemia." | ( Bennie, A; Gangaidzo, I; Gwanzura, C; Kiire, C; Lindenbaum, J; Moyo, A; Mudenge, B; Mukiibi, JM; Savage, D; Sitima, J, 1994) |
"Vitamin B12 deficiency is an uncommon disorder in a prosperous western country." | ( Bruin, MC; Prakken, AB; van Dijken, PJ; Veenhuizen, L; Waelkens, JJ, 1994) |
"Patients with vitamin B12 deficiency are exceedingly sensitive to neurologic deterioration following nitrous oxide anesthesia." | ( Flippo, TS; Holder, WD, 1993) |
"Vitamin B12 deficiency is known to be associated with signs of demyelination, usually in the spinal cord." | ( Lövblad, K; Nirkko, AC; Ozdoba, C; Ramelli, G; Remonda, L; Schroth, G, 1997) |
"Vitamin B12 deficiency is a systemic disease that often affects the nervous system." | ( Deuschl, G; Glocker, FX; Hemmer, B; Lücking, CH; Schumacher, M, 1998) |
"Vitamin B12 deficiency is estimated to affect 10%-15% of people over the age of 60, and the laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels." | ( Baik, HW; Russell, RM, 1999) |
"Vitamin B12 deficiency is thought to be uncommon, as the terminal ileum is relatively spared." | ( Dahele, A; Ghosh, S, 2001) |
"Vitamin B12 deficiency is common in untreated celiac disease, and concentrations should be measured routinely before hematinic replacement." | ( Dahele, A; Ghosh, S, 2001) |
"As vitamin B12 deficiency is caused by malabsorption in the gastrointestinal tract, oral supplementation is insufficient." | ( Franke, CL; Jongen, JC; Koehler, PJ, 2001) |
"Vitamin B12 deficiency is a common problem that affects the general population and the elderly in particular." | ( Dharmarajan, TS; Norkus, EP, 2001) |
"Vitamin B12 deficiency is a very rare disease of infants and young children in Europe." | ( Békési, A; Bocskai, E; Fogarasi, A; Neuwirth, M, 2001) |
"Vitamin B12 deficiency is common, with most patients lacking classic features of advanced severe deficiency." | ( Harper, CM; Payne, TA; Pittock, SJ, 2002) |
"Vitamin B12 deficiency is neither correlated with the time elapsed since surgery, nor with the ileum length." | ( Abd-el-Gawa, G; Abrahamsson, K; Hanson, E; Hjälmås, K; Norlén, L, 2002) |
"Diagnosis of vitamin B12 deficiency is typically based on measurement of serum vitamin B12 levels; however, about 50 percent of patients with subclinical disease have normal B12 levels." | ( Brown, DL; Oh, R, 2003) |
"Vitamin B12 deficiency is a common but under-recognized, yet easily treatable disorder in older adults." | ( Adiga, GU; Dharmarajan, TS; Norkus, EP, 2003) |
"In conclusion, vitamin B12 deficiency is one of the causes of recurrent pregnancy loss associated with HHcy, and serum B12 should be measured systematically in this circumstance." | ( Bayle, J; Bongain, A; Candito, M; Dor, JF; Gillet, Y; Magnaldo, S; Van Obberghen, E, 2003) |
"Vitamin B12 deficiency is conventionally diagnosed if serum vitamin B12 < 150 pmol/l ('low vitamin B12')." | ( Bates, C; Birks, J; Breeze, E; Clarke, R; Fletcher, A; Grimley Evans, J; Johnston, C; Nexo, E; Prentice, A; Refsum, H; Schneede, J; Scott, JM; Sherliker, P; Ueland, PM; Whitlock, G, 2004) |
"Pure or mixed vitamin B12 deficiency is an important but yet not commonly recognized cause of anaemia among these children." | ( Gomber, S; Kela, K; Lal, A; Madan, N, 2003) |
"Dietary vitamin B12 deficiency is a severe problem in the Indian subcontinent, Mexico, Central and South America, and selected areas in Africa." | ( Allen, RH; Stabler, SP, 2004) |
"The contribution of vitamin B12 deficiency is discussed." | ( Andrès, E; Blicklé, JF; Brogard, JM; Noel, E; Rousso, E, 2005) |
"Vitamin B12 deficiency is a diagnosis that must not be overlooked." | ( Bilic, E; Juric, S; Zagar, M, 2004) |
"Vitamin B12 deficiency is surprisingly common among patients with vascular disease, and, in the setting of folic acid fortification, low serum vitamin B12 levels are a major determinant of elevated homocysteine levels and increased carotid plaque area." | ( Allen, RH; Iemolo, F; Robertson, J; Spence, JD; Stabler, SP, 2005) |
"Vitamin B12 deficiency is common and rises with age." | ( Butler, CC; Cannings-John, R; Goringe, A; Hood, K; McCaddon, A; McDowell, I; Papaioannou, A; Vidal-Alaball, J, 2005) |
"Vitamin B12 deficiency is more prevalent in infancy in Sanliurfa province (at the southeast region of Turkey)." | ( Demir, N; Erel, O; Koc, A; Kocyigit, A; Mil, Z; Sevinc, E; Soran, M, 2006) |
"Vitamin B12 deficiency is related to the extent of ileal resection but has rarely impact on anaemia." | ( Gasche, C; Kulnigg, S, 2006) |
"Vitamin B12 deficiency is usually evoked in presence of compatible hematologic or clinical (usually neurologic) signs." | ( Iten, A; Mach-Pascual, S; Rufenacht, P, 2008) |
"Vitamin B12 deficiency is a longstanding public health problem which affects more than 20% of the elderly population." | ( Attarian, S; Chiche, L; Faivre, A; Franques, J; Gutierrez, M; Koric, L; Pouget, J, 2010) |
"Vitamin B12 deficiency is remarkably common in elderly patients in neurology department, with various and atypical clinical manifestations, and the neurological symptoms are more common than megaloblastic anemia symptoms." | ( Shao, FY; Wang, YH; Yan, F; Ye, G; Zhang, WB; Zhang, XH; Zheng, YY, 2009) |
"Vitamin B12 deficiency is an important nutritional disorder causing neurological manifestations of myelopathy, neuropathy and dementia." | ( Basha, MM; Madhavan, R; Puntambekar, P; Zak, IT, 2009) |
"Vitamin B12 deficiency is a common long-term sequelae after total gastrectomy." | ( Choi, SH; Hyung, WJ; Kim, CB; Kim, HI; Noh, SH; Song, KJ, 2011) |
"Vitamin B12 deficiency is an uncommon cause of pyrexia." | ( Bharti, V; Gupta, D; Kashyap, R; Kumar, J; Kumar, V; Negi, RC; Raina, S; Singh, K, 2011) |
"Ataxia due to vitamin B12 deficiency is a rare problem which in 20-25% of cases is not accompanied by anaemia." | ( Jansen, L; van der Linden, CM, 2013) |
"Vitamin B12 deficiency is prevalent in many countries of origin of refugees." | ( Benson, J; Correa-Velez, I; Kay, M; Lorimer, MF; Phillips, C; Ratcliff, AJ; Webber, MT, 2013) |
"Vitamin B12 deficiency is an important population health issue in newly-arrived refugees from many countries." | ( Benson, J; Correa-Velez, I; Kay, M; Lorimer, MF; Phillips, C; Ratcliff, AJ; Webber, MT, 2013) |
"Vitamin B12 deficiency is a well recognized cause of posterolateral myelopathy." | ( Garg, RK; Khanna, VK; Malhotra, HS; Praharaj, HN; Singh, MK; Verma, R, 2013) |
"Vitamin B12 deficiency is diagnosed by measurements of total B12, holo-transcobalamin (holoTC), methylmalonic acid (MMA) and total homocysteine (Hcy) in blood." | ( Fedosov, SN, 2013) |
"Vitamin B12 deficiency is common in older people, and may be responsible for reversible dementia." | ( Albers, U; de-Mendonça, A; Guerreiro, M; Martins, IP; Santana, I; Silva, D; Verdelho, A; Vicente, M, 2013) |
"Vitamin B12 deficiency is rare in children, with nonspecific symptoms including failure to thrive, vomiting, anorexia, and neurologic changes with or without hematologic disturbances." | ( Brandow, A; Dobrozsi, S; Flood, VH; Panepinto, J; Scott, JP, 2014) |
"Vitamin B12 deficiency is a treatable cause of failure to thrive and developmental regression, involuntary movements, and anemia." | ( Belgemen, T; Carman, KB; Yis, U, 2013) |
"Vitamin B12 deficiency is associated with a wide spectrum of neuro-psychiatric manifestations." | ( Kaddu-Mukasa, M; Kibirige, D; Waiswa, M; Wekesa, C, 2013) |
"Vitamin B12 deficiency is common in certain populations, such as in India, where there is also a rising prevalence of Type 2 diabetes, obesity and their complications." | ( Finer, S; Hitman, G; Saravanan, P; Yajnik, C, 2014) |
"Vitamin B12 deficiency is generally diagnosed by the plasma vitamin B12 level." | ( Kurpad, AV; Sowmya, S; Sucharita, S; Thomas, T; Vaz, M, 2013) |
"Vitamin B12 deficiency is highly prevalent worldwide and has been linked to hematologic, neurologic and psychiatric diseases." | ( Ajlouni, K; Batieha, A; Belbisi, A; El-Khateeb, M; Hyassat, D; Jaddou, H; Khader, Y, 2014) |
"Vitamin B12 deficiency is associated with many adverse health outcomes and is highly prevalent worldwide." | ( Herrán, OF; Villamor, E; Ward, JB, 2015) |
"Although vitamin B12 deficiency is a well-known cause of hematological and neuropsychiatric illness, the presentation of combined severe pancytopenia, demyelination and prominent psychiatric impairment is rare." | ( Leung, AA; Pandya, R; Rannelli, L; Watterson, R, 2014) |
"Vitamin B12 deficiency is common." | ( Rehman, HU, 2014) |
"The prevalence of vitamin B12 deficiency is common in type 2 diabetes patients and is associated with adverse lipid parameters." | ( Adaikalakoteswari, A; Anjana, RM; Gokulakrishnan, K; Jayashri, R; Kumar, S; McTernan, PG; Mohan, V; Patel, V; Pradeepa, R; Saravanan, P; Sukumar, N; Tripathi, G; Venkataraman, H, 2014) |
"Vitamin B12 deficiency is extremely common in strict vegetarians and their variants." | ( Bravo J, P; Ibarra C, J; Paredes M, M, 2014) |
"Vitamin B12 deficiency is often not suspected by the pediatrician in healthy infants." | ( Bravo J, P; Ibarra C, J; Paredes M, M, 2014) |
"Vitamin B12 deficiency is common among the elderly." | ( Wong, CW, 2015) |
"Vitamin B12 deficiency is a common condition which can present with non-specific clinical features, and in severe cases with neurological or haematological abnormalities." | ( Shipton, MJ; Thachil, J, 2015) |
"Although vitamin B12 deficiency is not a primary target of newborn screening (NBS) programs, measurements of propionylcarnitine (C3) and its ratios with acetylcarnitine (C3/C2) and palmitoylcarnitine (C3/C16) may incidentally identify vitamin B12-deficient newborns." | ( Dayaldasani, A; Pérez-Valero, V; Rodríguez-Espinosa, M; Rueda, I; Ruiz-Escalera, J; Yahyaoui, R, 2014) |
"Nutritional vitamin B12 deficiency is a treatable cause of neurologic dysfunction in infants." | ( Goraya, JS; Kaur, S; Mehra, B, 2015) |
"Overall, vitamin B12 deficiency is common in the institutionalized elderly, however macrocytosis cannot predict deficiency." | ( Cheng, JN; Ip, CY; Leung, CP; Leung, CS; Siu, CY; Wong, CW, 2015) |
"Vitamin B12 deficiency is common in patients with CD." | ( Anderson, SH; Griffin, N; Harrington, DJ; Irving, PM; Kariyawasam, VC; Mogan, SB; Pantelidou, M; Patel, KV; Porté, F; Sanderson, JD; Sobczyńska-Malefora, A; Ward, MG, 2015) |
"Vitamin B12 deficiency is associated with a global cognition decline with language, orientation, and mental manipulation selectively impaired." | ( Hsu, YH; Huang, CF; Lo, CP; Tu, MC; Wang, TL, 2016) |
"Vitamin B12 deficiency is a risk factor for bone disorders via mechanisms not fully understood." | ( Kawata, T; Kimira, Y; Mano, H; Shiga, T; Suzuki, T; Tadokoro, T; Yamamoto, Y, 2016) |
"Vitamin B12 deficiency is common after bariatric surgery." | ( Boer, AK; Nienhuijs, SW; Said, M; Smelt, HJ; Smulders, JF, 2016) |
"Vitamin B12 deficiency is associated with many adverse health outcomes and is highly prevalent worldwide." | ( Correa-Bautista, JE; Lobelo, F; Martínez-Torres, J; Meneses-Echávez, JF; Ramírez-Vélez, R, 2016) |
"Functional vitamin B12 deficiency is common in subjects with advanced malignancy." | ( Solomon, LR, 2016) |
"Vitamin B12 deficiency is often asymptomatic early in its course; however, once it manifests, particularly with neurological symptoms, reversal by dietary changes or supplementation becomes less effective." | ( Colt, S; Erickson, D; Hohenstein, J; Lee, S; Mehta, S; O'Dell, D, 2016) |
"Vitamin B12 deficiency is a rare diagnosis in young children." | ( Gajudhur, J; Mahoney, D; Mehta, PS; Slone, JS, 2016) |
"Treatment of Vitamin B12 deficiency is simple, but may be lifelong." | ( Linton, DM; Romain, M; Stav, I; Sviri, S; van Heerden, PV, 2016) |
"Vitamin B12 deficiency is mostly caused by insufficient gastro-intestinal absorption and in rare conditions by Transcobalamin (TC) deficiency." | ( Griffioen, PH; Heil, SG; Lindemans, J; van Dam-Nolen, DHK, 2017) |
"Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations." | ( Goodbred, AJ; Langan, RC, 2017) |
"Vitamin B12 deficiency is common in older individuals." | ( Bailey-Wilson, JE; Brody, LC; Cropp, CD; Cunningham, C; Diaz, JEL; McNulty, H; Mills, JL; Molloy, AM; Pangilinan, F; Sanchez, E; Shane, B; Velkova, A; Wilson, AF, 2017) |
"Vitamin B12 deficiency is classically treated with intramuscular injections." | ( Akoğlu, HA; Bozaykut, A; Özdemir, GN; Sezer, RG, 2018) |
"Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms, as well as the relationship between eating meat and B12 levels, is unclear." | ( Giat, E; Yom-Tov, E, 2018) |
"Vitamin B12 deficiency is highly prevalent in pregnant Indian women." | ( Anand, S; Duggan, CP; Jayachandra, M; Kurpad, AV; Srinivasan, K; Strand, TA; Thomas, S; Thomas, T, 2019) |
"Background Vitamin B12 deficiency is common worldwide and is also linked to several diseases including autoimmune atrophic gastritis (AAG)." | ( Flores, E; Leiva-Salinas, C; López-Garrigós, M; Salinas, M, 2020) |
"Vitamin B12 deficiency is a common micronutrient deficiency in infants." | ( Baris, HE; Boran, P; Dinh, DM; Erzik, C; Kepenekli, E; Soysal, A, 2020) |
"Diagnosis of vitamin B12 deficiency is difficult, as there is no conclusive single test for this disorder." | ( de Jong, WHA; Huls, G; van der Klauw, MM; Wolffenbuttel, BHR; Wouters, HJCM, 2020) |
"The prevalence of vitamin B12 deficiency is considerable among diabetic patients on metformin therapy." | ( Al Mahrezi, AM; Al-Gahhafi, M; Al-Hamdi, A; Al-Mamari, A; Al-Roshdi, S; Jaju, S, 2020) |
"Vitamin B12 deficiency is prevalent worldwide especially in vegetarian communities." | ( Jain, R; Kalyan G, B; Mittal, M, 2020) |
"Vitamin B12 deficiency is one of the main complications of vegetarianism." | ( Casuriaga Lamboglia, AL; Giachetto Larraz, G; Pérez Mathon, N, 2020) |
"Indeed, vitamin B12 deficiency is a common denominator between the elderly and those with diabetes." | ( Wee, AKH, 2021) |
"Vitamin B12 deficiency is common and affects cell division and differentiation, erythropoiesis, and the central nervous system." | ( Chandyo, RK; Hysing, M; Kvestad, I; McCann, A; Ranjitkar, S; Shrestha, LS; Shrestha, M; Shrestha, PS; Strand, TA; Ueland, PM; Ulak, M, 2020) |
"Vitamin B12 deficiency is common in outpatients and inpatient populations, with potentially severe neuropsychiatric and hematological impact, which requires timely diagnosis and treatment." | ( Alberio, L; Bruttin, JP; Favre, L; Gavillet, M; Gilet, P; Grandoni, F, 2021) |
"Vitamin B12 deficiency is common worldwide and has been associated with poor sleep." | ( Chandyo, RK; Hysing, M; Kvestad, I; Ranjitkar, S; Schwinger, C; Shrestha, M; Strand, TA; Ulak, M, 2022) |
"Vitamin B12 deficiency is not an independent risk factor for cardiovascular disease." | ( Demir, MC; Kucukdemirci, O; Polat, E, 2022) |
"Vitamin B12 deficiency is a treatable condition, it should be suspected in infants presenting with hypotonicity." | ( Dilber, B; Eyüboğlu, İ, 2022) |
"Vitamin B12 deficiency is a cause of reversible dementia that must be ruled out in the evaluation of neurocognitive decline." | ( Benyaminov, F; Block, L; Wong, C, 2022) |
"Vitamin B12 deficiency is associated with cognitive impairment, hyperhomocysteinemia, and hippocampal atrophy." | ( Enomoto, S; Hamano, T; Ikawa, M; Ito, T; Kimura, H; Kimura, Y; Kuriyama, M; Nagata, M; Nakamoto, Y; Shirafuji, N; Ueno, A; Yamamura, O; Yamanaka, D, 2022) |
"In infants, vitamin B12 deficiency is mainly due to nutritional deficiencies related to maternal deficit." | ( Dapueto, G; García, L; Vomero, A, 2022) |
"Vitamin B12 deficiency is common in Ireland, The Irish Longitudinal Study on Aging (TILDA) survey indicates 12% of over 50s in Ireland are low or deficient." | ( MacCarthy, J; O'Donnell, O, 2023) |
"In summary, vitamin B12 deficiency is associated with increased risk of GDM, it is necessary to pay more attention to the balance of vitamin B12 and folic acid." | ( Cui, X; He, J; Ji, C; Jiang, D, 2022) |
"Vitamin B12 deficiency is also a known cause of optic neuropathy through mitochondrial dysfunction." | ( Catarino, CB; Klopstock, T; Kolarova, H; Priglinger, CS; Rudolph, G; von Livonius, B; Zibold, J, 2022) |
"Vitamin B12 deficiency is frequent among older adults and is a known risk factor for ischemic stroke." | ( Park, EJ, 2023) |
"Prevalence of vitamin B12 deficiency is occasionally found to be coexisting in patients with hypothyroidism causing persistence of symptoms concomitant to both diseases even on adequate thyroxine supplementation." | ( Chatterjee, T; Choudhary, S; Gupta, R, 2023) |
"Vitamin B12 deficiency is a public health problem among Brazilian children aged <2 y with vulnerable socioeconomic status." | ( Berti, TL; Castro, IRR; Farias, DR; Kac, G; Normando, P; Salvatte, K, 2023) |
Excerpt | Reference |
"A 17-year-old boy with vitamin B12 deficiency that occurred after a small bowel resection developed bilateral centrocecal scotomas during folic acid therapy and improved on therapy including vitamin B complex." | ( Behrens, M; Stambolian, D, 1977) |
"Seventeen patients were treated for vitamin B12 deficiency with i." | ( Skouby, AP, 1987) |
"However, there was evidence of vitamin B12 deficiency as shown by an abnormal deoxyuridine suppression test and by the response to treatment with physiological doses of vitamin B12." | ( Burman, JF; Doyle, DV; Mollin, DL; Murphy, MF; Sourial, NA; Tabaqchali, S, 1986) |
"In all participants with vitamin B12 deficiency who received treatment (15 of 21), methylmalonic acid and total homocysteine levels decreased substantially, confirming the deficiency before treatment." | ( Abrahm, JL; Allen, RH; Berry, GT; Chin, MM; Gracely, EJ; Stabler, SP; Sumner, AE, 1996) |
"Screening for vitamin B12 deficiency and thyroid disease is cheap and enables early diagnosis to be made and treatment to be started while it is still simple and can prevent the development of such serious conditions as dementia, depression, or irreversible tissue damage." | ( Bondeson, E; Eggertsen, R; Meisel, T, 1997) |
"Whether such treatment will result in vitamin B12 deficiency is controversial." | ( Gibril, F; Jensen, RT; Sutliff, VE; Termanini, B; Venzon, DJ; Yu, F, 1998) |
"To examine whether functional vitamin B12 deficiency exists even in HD patients with normal vitamin B12 concentrations, 15 HD patients (serum vitamin B12 concentrations, 250 to 2,100 pg/mL) were treated with vitamin B12 (mecobalamin, 1." | ( Funamizu, M; Hata, A; Hayashi, K; Hiejima, Y; Hirayama, H; Kawabata, M; Makita, Y; Nakamura, T; Saionji, K; Tago, K; Tajiri, M; Takano, H, 2002) |
"We describe an overview of vitamin B12 deficiency and the successful treatment of a patient's ongoing cutaneous hyperpigmentation." | ( Hoffman, CF; Palmer, DM; Papadopoulos, D, 2003) |
"Standard treatment of vitamin B12 deficiency involves regular intramuscular cobalamin administration." | ( Andrès, E; Barnier-Figue, G; Berthel, M; Kaltenbach, G; Kuntzmann, F; Martin-Hunyadi, C; Noblet-Dick, M; Noel, E; Perrin, AE; Vogel, T, 2003) |
"Neurological disorders in vitamin B12 deficiency should worsen when folate is administered without supplementation of vitamin B12." | ( Omura, K, 2004) |
"Most people with vitamin B12 deficiency are treated in primary care with intramuscular vitamin B12 which is a considerable source of work for health care professionals." | ( Butler, CC; Cannings-John, R; Goringe, A; Hood, K; McCaddon, A; McDowell, I; Papaioannou, A; Vidal-Alaball, J, 2005) |
"Once the diagnosis of vitamin B12 deficiency has been confirmed efficient treatment can be ensured either by injections every 2-3 month or by a daily dose of 1 mg vitamin B12." | ( Hvas, AM; Nexo, E, 2006) |
"The cost of the resources used to treat patients with vitamin B12 deficiency with intramuscular vitamin B12 was calculated as between 55." | ( Butler, CC; Potter, CC; Vidal-Alaball, J, 2006) |
"Switching patients with vitamin B12 deficiency from intramuscular to high-dose oral therapy and treating patients newly diagnosed with vitamin B12 deficiency with oral vitamin B12 from the outset could save resources in the medium and long term, and in newly diagnosed patients." | ( Butler, CC; Potter, CC; Vidal-Alaball, J, 2006) |
"Oral treatment of vitamin B12 deficiency is possible whatever the etiology, but it has only been validated in small series." | ( Iten, A; Mach-Pascual, S; Rufenacht, P, 2008) |
"It is recommended that patients with vitamin B12 deficiency be prescribed 1000 microg/day vitamin B12 orally, unless they have problems with swallowing or treatment compliance or have severe clinical symptoms." | ( Duyvendak, M; Veldhuis, GJ, 2009) |
"It is important to consider vitamin B12 deficiency as a cause, as speedy identification and treatment can help prevent permanent neurological damage." | ( Cocks, H; Green, R; Kara, N, 2011) |
"In Denmark, patients with vitamin B12 deficiency are usually treated for life with either Betolvex or Vibeden given as injections every third month." | ( Arendt, J; Nexø, E, 2011) |
"Patients with vitamin B12 deficiency were administered intramuscular cyanocobalamin." | ( Bulan, K; Demir, N; Doğan, M; Doğan, SZ; Kaba, S; Koç, A; Ozkol, HU, 2014) |
"He received treatment for vitamin B12 deficiency and appropriate nutritional counseling." | ( Chakrabarty, B; Dubey, R; Gulati, S; Kumar, A; Yoganathan, S, 2014) |
"There has been a paradigm shift in the treatment of vitamin B12 deficiency such that MeCbl is being extensively used and promoted." | ( Billa, G; Thakkar, K, 2015) |
"The prevalence rates of vitamin B12 deficiency (<191 ng/L) were 27% and 12% in Europeans and Indians, respectively and higher in metformin treated type 2 diabetes patients." | ( Adaikalakoteswari, A; Anjana, RM; Gokulakrishnan, K; Jayashri, R; Kumar, S; McTernan, PG; Mohan, V; Patel, V; Pradeepa, R; Saravanan, P; Sukumar, N; Tripathi, G; Venkataraman, H, 2014) |
"The prevalence of vitamin B12 deficiency in the metformin-treated patients was significantly higher in the S+M group compared with the I+M group (17." | ( Ahn, YB; Kang, D; Ko, SH; Lim, TS; Park, YM; Yun, JS, 2014) |
"Nutritional vitamin B12 deficiency is a treatable cause of neurologic dysfunction in infants." | ( Goraya, JS; Kaur, S; Mehra, B, 2015) |
"Cases of vitamin B12 deficiency were identified as those who had received a diagnosis of vitamin B12 deficiency, and/or were receiving a treatment for vitamin B12 deficiency." | ( Kergoat, MJ; Perreault, S; Presse, N, 2016) |
"Treatment of Vitamin B12 deficiency is simple, but may be lifelong." | ( Linton, DM; Romain, M; Stav, I; Sviri, S; van Heerden, PV, 2016) |
"There is no consensus about the optimal treatment of vitamin B12 deficiency." | ( Pouwels, S; Smelt, HJ; Smulders, JF, 2017) |
"Patients with severe DED and vitamin B12 deficiency (group 1, n = 45) received parenteral vitamin B12 supplement + topical treatment (artificial tears treatment + cyclosporine), and patients with severe DED and normal serum vitamin B12 level (group 2, n = 45) received only topical treatment (artificial tears treatment + cyclosporine)." | ( Akdemir, MO; Ozen, S; Ozer, MA, 2017) |
"Standard treatment of vitamin B12 deficiency has not been well established in childhood, the ideal amount of supplemental vitamin B12 is not clear." | ( Akoğlu, HA; Bozaykut, A; Özdemir, GN; Sezer, RG, 2018) |
"Although, oral replacement for vitamin B12 deficiency has been proved to be effective in adults, it is mainly treated with parenteral therapy." | ( Akoğlu, HA; Bozaykut, A; Özdemir, GN; Sezer, RG, 2018) |
"Severe vitamin B12 deficiency can result in serious complications if undiagnosed or untreated." | ( Asencio, A; Flores, E; Leiva-Salinas, C; Leiva-Salinas, M; López-Garrigós, M; Lugo, J; Salinas, M, 2018) |
"To compare the prevalence of vitamin B12 deficiency and peripheral neuropathy between two groups of type 2 diabetes mellitus (T2DM) patients treated with or without metformin, and to determine factors associated with vitamin B12 deficiency therapy and dietary intake of vitamin B12." | ( Abdelhay, O; Abuhaimed, SN; Al-Asmari, AK; AlHarbi, NG; Alharbi, TJ; Alkhashan, HI; AlRasheed, AN; Bin Rsheed, AM; Mohammed, N; Tourkmani, AM, 2018) |
"There are several methods to treat vitamin B12 deficiency (VB12d): intramuscular (IM), oral, sublingual (SL), and intranasal vitamin B12 (VB12) preparations." | ( Ayalon-Dangur, I; Ayalon-Dangur, R; Bensky, MJ; Gafter-Gvili, A; Koren, G; Naamany, E; Shiber, S, 2019) |
"High prevalence of vitamin B12 deficiency was observed in metformin-treated patients with type 2 diabetes." | ( Ashor, AW; Khalaf, KM; Khudhair, MS, 2019) |
"To determine the role of vitamin B12 deficiency in pernicious anemia and the efficacy of oral vitamin B12 replacement therapy given regardless of the etiology, and to compare the endoscopic and pathological findings in patients diagnosed with vitamin B12 deficiency." | ( Çekin, AH; Dolu, S; Harmandar, FA, 2020) |
"In this study of 216 patients with vitamin B12 deficiency, stomach pathologies which could cause vitamin B12 deficiency (atrophic gastritis, HP, PA) and the responses to oral replacement therapy were investigated." | ( Çekin, AH; Dolu, S; Harmandar, FA, 2020) |
"The prevalence of vitamin B12 deficiency is considerable among diabetic patients on metformin therapy." | ( Al Mahrezi, AM; Al-Gahhafi, M; Al-Hamdi, A; Al-Mamari, A; Al-Roshdi, S; Jaju, S, 2020) |
"The infants of mothers with nutritional vitamin B12 deficiency may develop sudden abnormal movements following peroral vitamin B12 therapy and that the differential diagnosis of these disorders is highly important for the prevention of long-term neurological sequela by treatment." | ( Dilber, B; Reis, GP, 2021) |
"Oral supplementation for vitamin B12 deficiency was conducted/realized in three patients, while one patient was treated with parenteral doses." | ( da Silva, WR; da Silveira, ÉJD; de Morais, EF; de Oliveira, PT; Dos Santos, AA; Xerez, MC, 2022) |
"İnfantile nutritional vitamin B12 deficiency, which can be a source of persistent neurological deficits during the long term, should be treated to allow the patient to allow healthy neuro-development for infants." | ( Dilber, B; Eyüboğlu, İ, 2022) |
"The types of clinical symptoms with Vitamin B12 deficiency that improved with Vitamin B12 treatment and the degree of improvement were also similar." | ( Aoyama, T; Cho, H; Hara, K; Kano, K; Komori, K; Maezawa, Y; Oshima, T; Rino, Y; Saigusa, Y; Segami, K; Senuki, K; Suzuki, Y; Tamagawa, H; Tamura, J; Tsuchida, K; Yamakawa, M; Yukawa, N, 2022) |
"To describe the prevalence of vitamin B12 deficiency among Jordanian patients with type 2 diabetes mellitus treated with metformin and to compare the findings with those who did not receive metformin." | ( Al-Fawaeir, S; Al-Odat, I, 2022) |
"Instead, his clinical picture portrayed vitamin B12 deficiency, leading to misdiagnosis and subsequent treatment delay." | ( Azim, D; Kumar, S; Nanjiani, D; Nasim, S; Parkash, O; Sharma, N, 2023) |
"To evaluate the prevalence of vitamin B12 deficiency in Chinese patients with type 2 diabetes mellitus receiving metformin treatment and to investigate the effects of metformin daily dose and treatment duration on the prevalence of vitamin B12 deficiency and peripheral neuropathy (PN)." | ( Bi, Y; Chen, S; Gao, L; Ji, L; Lei, M; Liu, F; Liu, X; Lu, Y; Ran, X; Shen, X; Su, Q; Wang, Y; Zhao, D, 2023) |
"The prevalence of vitamin B12 deficiency among T2DM patients on metformin treatment in this study was high (48." | ( Al Quran, T; Al-Momani, R; Allan, H; Alsaleh, M; Aqel, HT; Bataineh, Z; Khader, A, 2023) |