A Daphnia metabolite produced by the species Daphnia magna.
| Member | Definition | Class |
|---|
| 15-hydroxytestosterone | An androstanoid that is testosterone substituted by a alpha-hydroxy group at position 15. A natural product found in Daphnia magna exposed to the biocide tributyltin. | 15alpha-hydroxytestosterone |
| 5 alpha-androstane-3 alpha,17 beta-diol | The 5alpha-stereoisomer of androstane-3alpha,17beta-diol. | 5alpha-androstane-3alpha,17beta-diol |
| 5 alpha-androstane-3 beta,17 beta-diol | An androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone. | 5alpha-androstane-3beta,17beta-diol |
| acetic acid | A simple monocarboxylic acid containing two carbons. | acetic acid |
| adenine | The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. | adenine |
| aminomalonic acid | An amino dicarboxylic acid that is malonic acid in which one of the methylene hydrogens has been replaced by an amino group. | aminomalonic acid |
| androstenedione | A 3-oxo Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads. | androst-4-ene-3,17-dione |
| cadaverine | An alkane-alpha,omega-diamine comprising a straight-chain pentane core with amino substitutents at positions 1 and 5. A colourless syrupy liquid diamine with a distinctive unpleasant odour, it is a homologue of putresceine and is formed by the bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue. It is also found in plants such as soyabean. | cadaverine |
| carnosine | A dipeptide that is the N-(beta-alanyl) derivative of L-histidine. | carnosine zwitterion; carnosine |
| choline | A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. | choline |
| citrulline | Zwitterionic form of L-citrulline having an anionic carboxy group and a protonated amino group; major species at pH 7.3. | L-citrulline zwitterion; L-citrulline |
| dihydrotestosterone | A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5. | 17beta-hydroxy-5alpha-androstan-3-one |
| dimethylglycine | An N-methylglycine that is glycine carrying two N-methyl substituents. | N,N-dimethylglycine zwitterion; N,N-dimethylglycine |
| endolysin | A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6. | lysine |
| glutaric acid | An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. | glutaric acid |
| isobutyric acid | A branched fatty acid comprising propanoic acid carrying a methyl branch at C-2. | isobutyric acid |
| lactic acid | A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. | 2-hydroxypropanoic acid |
| margaric acid | A C17 saturated fatty acid and trace component of fats in ruminants. | heptadecanoic acid |
| myristic acid | A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat. | tetradecanoic acid |
| p-aminohippuric acid | An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow. | p-aminohippuric acid |
| palmitic acid | A straight-chain, sixteen-carbon, saturated long-chain fatty acid. | hexadecanoic acid |
| pelargonic acid | A C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers. | nonanoic acid |
| pentadecanoic acid | A straight-chain saturated fatty acid containing fifteen-carbon atoms. | pentadecanoic acid |
| phenylalanine | An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group. | phenylalanine |
| pyrazines | A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms. | pyrazine |
| pyrimidine | The parent compound of the pyrimidines; a diazine having the two nitrogens at the 1- and 3-positions. | pyrimidine |
| racemethionine | A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. | methionine zwitterion; methionine |
| stearic acid | A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics. | octadecanoic acid |
| tricosanoic acid | A very long-chain fatty acid that is tricosane in which one of the methyl groups has been oxidised to the corresponding carboxylic acid. | tricosanoic acid |
| tryptophan | An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3. | tryptophan zwitterion; tryptophan |
| turanose | A glycosylfructose isolated from Daphnia magna. | turanose |
| uracil | A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. | uracil |
| urea | A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). | carbamimidic acid; urea |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 23.8770 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 56.7652 | 3 | 7 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 223.8720 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 19.9116 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 10.9767 | 12 | 64 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 25.6780 | 2 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 18.8336 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.1694 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 18.8336 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 251.1890 | 2 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 32.5167 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 26.8346 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 32.5167 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 26.8346 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 38.9133 | 1 | 2 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0251 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 5.6234 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 27.2869 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.0751 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 17.2467 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 27.2869 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.5193 | 1 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 12.3018 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 14.2191 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 22.2595 | 1 | 4 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 6.9913 | 1 | 7 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 16.8336 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 17.4955 | 12 | 68 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 26.8406 | 3 | 14 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 35.6958 | 6 | 59 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 27.6567 | 3 | 5 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 106.1010 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 14.2191 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 19.6741 | 2 | 10 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.6436 | 2 | 17 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 24.8033 | 2 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 18.2995 | 4 | 14 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 45.6632 | 1 | 4 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 31.3736 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 38.6500 | 2 | 3 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 36.5355 | 2 | 5 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 70.3602 | 2 | 7 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 5.0119 | 2 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 31.3736 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0251 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0251 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 13.3218 | 1 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 31.6228 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 62.0367 | 2 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 27.3979 | 2 | 3 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 35.4813 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 44.4443 | 3 | 9 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 15.8184 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 27.5912 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 31.1954 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 13.5128 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 14.1254 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 25.3640 | 3 | 10 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 14.9786 | 1 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 40.1236 | 2 | 3 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 28.2795 | 1 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 41.5578 | 5 | 15 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 31.6228 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 33.9872 | 2 | 11 |
| progesterone receptor | Homo sapiens (human) | Potency | 2.5011 | 3 | 10 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 91.0630 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 26.2021 | 2 | 14 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 0.0060 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 39.6016 | 3 | 17 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 30.5612 | 3 | 15 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 38.9097 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 38.9097 | 2 | 4 |
| Smad3 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 31.3736 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 1.5843 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 18.9417 | 1 | 5 |
| TDP1 protein | Homo sapiens (human) | Potency | 25.1816 | 2 | 8 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 37.7756 | 2 | 14 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 23.7531 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 13.7106 | 3 | 3 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 17.6081 | 2 | 2 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 59.6649 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 20.7425 | 2 | 6 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 24.2247 | 4 | 9 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 45.6632 | 1 | 4 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 8.8250 | 1 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 3,013.0100 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 4.0100 | 2 | 2 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Ki | 0.0002 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 85.9000 | 1 | 1 |
| Androgen receptor | Homo sapiens (human) | IC50 | 5.0026 | 26 | 26 |
| Androgen receptor | Mus musculus (house mouse) | IC50 | 0.0010 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 2.2350 | 9 | 11 |
| Androgen receptor | Homo sapiens (human) | Ki | 0.0014 | 19 | 19 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 0.0005 | 6 | 6 |
| Aromatase | Homo sapiens (human) | IC50 | 0.2800 | 2 | 2 |
| Aromatase | Homo sapiens (human) | Ki | 0.4562 | 4 | 4 |
| Beta-glucuronidase | Escherichia coli K-12 | IC50 | 430.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 2 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6300 | 1 | 1 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | Ki | 0.0002 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 13.3000 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.4500 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 0.6300 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 0.6500 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 11.0000 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 0.0440 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 0.5400 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 0.7400 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 0.4200 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 0.3800 | 1 | 1 |
| Chain A, Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 0.8020 | 1 | 1 |
| Chain A, meta-Cleavage product hydrolase | Pseudomonas fluorescens | Ki | 2,900.0000 | 1 | 1 |
| Chain A, MTA/SAH nucleosidase | Escherichia coli | Ki | 300.0000 | 1 | 1 |
| Chain A, Uracil-DNA Glycosylase | Thermus thermophilus | Ki | 0.0880 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 1.5500 | 1 | 1 |
| Corticosteroid-binding globulin | Homo sapiens (human) | Ki | 4.3134 | 1 | 3 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Dynamin-1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | Ki | 1.3055 | 2 | 4 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | IC50 | 0.9300 | 1 | 1 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 0.3360 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| Fibrinogen C domain-containing protein 1 | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Free fatty acid receptor 2 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| G-protein coupled receptor 84 | Homo sapiens (human) | Ki | 2.6400 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 1.8670 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 0.5400 | 1 | 1 |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 2 | 2 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 4,000.0000 | 2 | 3 |
| High affinity choline transporter 1 | Mus musculus (house mouse) | IC50 | 1.6000 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 15.8090 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Ki | 6.7150 | 1 | 1 |
| Mineralocorticoid receptor | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 2 | 2 |
| Mineralocorticoid receptor | Homo sapiens (human) | IC50 | 0.3600 | 1 | 1 |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0002 | 1 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 34.0000 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 42.2500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 38.7500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 35.2000 | 4 | 5 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 41.5000 | 3 | 4 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Ki | 2,350.0000 | 1 | 2 |
| Plasma kallikrein | Homo sapiens (human) | IC50 | 0.0031 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| Progesterone receptor | Oryctolagus cuniculus (rabbit) | IC50 | 0.4400 | 2 | 2 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 4 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 500.0000 | 1 | 4 |
| Protein cereblon | Homo sapiens (human) | IC50 | 415.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | Ki | 212.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP15 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Sex hormone-binding globulin | Homo sapiens (human) | IC50 | 0.0038 | 1 | 1 |
| Sex hormone-binding globulin | Rattus norvegicus (Norway rat) | IC50 | 0.0230 | 1 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Solute carrier family 15 member 1 | Rattus norvegicus (Norway rat) | Ki | 8,000.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | IC50 | 28.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 66.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 55.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 1,050.0000 | 3 | 3 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 217.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 2,036.3333 | 3 | 3 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 2,918.2510 | 1 | 4 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 46.9000 | 2 | 3 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 6.0200 | 2 | 2 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 8.0483 | 1 | 4 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 19.6000 | 1 | 1 |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | Ki | 683.0000 | 3 | 3 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 0.5693 | 6 | 6 |
| Toll-like receptor 2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 5.5500 | 1 | 2 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 6,470.0000 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 6,470.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 43.2500 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Androgen receptor | Homo sapiens (human) | EC50 | 0.0058 | 26 | 26 |
| Androgen receptor | Mus musculus (house mouse) | EC50 | 0.0040 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0019 | 2 | 2 |
| Androgen receptor | Homo sapiens (human) | Kd | 0.0002 | 1 | 1 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | EC50 | 0.0060 | 2 | 7 |
| Chain A, Acetylcholinesterase | Mus musculus (house mouse) | Kd | 930.0000 | 1 | 7 |
| Chain A, Aspartate Aminotransferase | Escherichia coli | Kd | 1,500.0000 | 1 | 1 |
| Chain A, Choline-binding protein | Bacillus subtilis subsp. subtilis str. JH642 | Kd | 30.5000 | 1 | 1 |
| Chain A, Glycine betaine/carnitine/choline-binding protein | Bacillus subtilis | Kd | 28.0000 | 1 | 4 |
| Chain A, MUSCLE FATTY ACID BINDING PROTEIN | Homo sapiens (human) | Kd | 0.9600 | 1 | 6 |
| Chain A, Phenylethanolamine N-methyltransferase | Homo sapiens (human) | Kd | 180.0000 | 1 | 13 |
| Chain A, Protein (aspartate Aminotransferase) | Escherichia coli | Kd | 1,500.0000 | 1 | 1 |
| Chain A, Putative Glycine Betaine-binding Abc Transporter Protein | Sinorhizobium meliloti | Kd | 2.3000 | 1 | 2 |
| Chain A, Ribosome-inactivating protein 3 | Zea mays | Kd | 0.0063 | 1 | 1 |
| Chain A, Ribosome-inactivating protein alpha-trichosanthin | Trichosanthes kirilowii | Kd | 260.0000 | 1 | 1 |
| Chain A, Ricin A chain | Ricinus communis (castor bean) | Kd | 700.0000 | 1 | 1 |
| Chain A, Sex Hormone-Binding Globulin | Homo sapiens (human) | Kd | 0.0009 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | Kd | 0.8020 | 1 | 1 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Kd | 81.5000 | 1 | 2 |
| Free fatty acid receptor 2 | Homo sapiens (human) | EC50 | 250.0000 | 1 | 1 |
| Free fatty acid receptor 3 | Homo sapiens (human) | EC50 | 12.0000 | 1 | 1 |
| Free fatty acid receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 30.0000 | 1 | 1 |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | EC50 | 5.7500 | 1 | 2 |
| G-protein coupled receptor 84 | Homo sapiens (human) | EC50 | 31.0620 | 4 | 5 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0164 | 1 | 2 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | EC50 | 29.3333 | 2 | 3 |
| Progesterone receptor | Homo sapiens (human) | EC50 | 8.2000 | 1 | 1 |
| Sex hormone-binding globulin | Homo sapiens (human) | Kd | 0.0119 | 1 | 3 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 0.9000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 0.9700 | 1 | 2 |