An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18).
| Member | Definition | Class |
|---|
| bongkrekic acid | A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group. It is produced by the bacterium Burkholderia gladioli and implicated in outbreaks of food-borne illness involving coconut and corn-based products in Indonesia and China. | bongkrekic acid |
| caffeic acid | A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common. | caffeic acid |
| ellagic acid | An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. | ellagic acid |
| ethacrynic acid | An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor. | etacrynic acid |
| hypochlorous acid | A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water. | hypochlorous acid |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 0.6362 | 1 | 3 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 14.5791 | 2 | 4 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 10.6822 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.9680 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.7943 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 26.5211 | 10 | 15 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 32.6427 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 68.1016 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 16.9441 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 68.1016 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 6.3221 | 1 | 3 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 40.8519 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 40.8519 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 13.7060 | 2 | 4 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 28.0076 | 1 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 3.4619 | 1 | 3 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 8.0749 | 2 | 5 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 56.2341 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 1.6661 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 7.0634 | 3 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 11.5467 | 2 | 5 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 0.0562 | 2 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 1.6661 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 0.3604 | 2 | 2 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 20.2208 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 3.8902 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 2.1317 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 2.6412 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 6.0457 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 0.1585 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 40.1136 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 5.0336 | 1 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 0.3905 | 1 | 3 |
| endonuclease IV | Escherichia coli | Potency | 19.9526 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 32.8890 | 9 | 14 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 42.8828 | 2 | 4 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 40.0956 | 6 | 12 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 26.6656 | 1 | 3 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 17.8509 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 16.4902 | 3 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 36.1898 | 1 | 2 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 63.0957 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 3.8902 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 18.1965 | 2 | 8 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 18.3133 | 3 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 33.0478 | 3 | 6 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 12.0887 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.0141 | 1 | 1 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 31.4115 | 1 | 5 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 22.2036 | 2 | 4 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 13.6462 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 21.4509 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 54.0951 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 19.0843 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 3.8902 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 32.8564 | 2 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 34.8705 | 3 | 3 |
| IDH1 | Homo sapiens (human) | Potency | 9.2432 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 3.8902 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 3.8902 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 3.8978 | 1 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 7.7195 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 32.7334 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 23.1102 | 2 | 8 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 62.0506 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 3.9811 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 13.2188 | 4 | 8 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 37.5780 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 30.1423 | 2 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 23.0103 | 3 | 6 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 40.3458 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 4.5479 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 32.4743 | 3 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 35.4863 | 4 | 6 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 0.8913 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 49.1748 | 1 | 5 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 4.4668 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 3.7842 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.8010 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 32.5108 | 2 | 3 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 36.1049 | 2 | 5 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 67.8334 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 43.0527 | 3 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 25.8488 | 4 | 6 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 0.3604 | 2 | 2 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 29.8816 | 1 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 17.5582 | 1 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 28.3447 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 28.3447 | 2 | 4 |
| Smad3 | Homo sapiens (human) | Potency | 30.3001 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 19.9526 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 21.0172 | 2 | 9 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 35.4813 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 29.8816 | 1 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 34.7816 | 2 | 5 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 34.9134 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 4.4668 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 4.4668 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 50.4512 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 54.5581 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.1741 | 3 | 5 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 17.4863 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 24.1634 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 2.6679 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 4.5110 | 2 | 2 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 4.9500 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 8.5000 | 1 | 1 |
| 14 kDa phosphohistidine phosphatase | Homo sapiens (human) | IC50 | 18.3000 | 1 | 1 |
| 14 kDa phosphohistidine phosphatase | Homo sapiens (human) | Ki | 183.0000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 1.8500 | 1 | 1 |
| 5'-nucleotidase | Mus musculus (house mouse) | IC50 | 0.0400 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 4.9500 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 8.5000 | 1 | 1 |
| acetyl-CoA acetyltransferase/HMG-CoA reductase | Enterococcus faecalis | IC50 | 1,265.3900 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 132.9200 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 10.5700 | 3 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 7.6150 | 2 | 2 |
| Aldehyde oxidase 1 | Cavia porcellus (domestic guinea pig) | Ki | 4.5300 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 0.2000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 200.0000 | 2 | 2 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 0.2600 | 1 | 1 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 5,000.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 95.9000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 2.4800 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 2.5000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 3.9000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 20.7000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 0.6000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 2.0500 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 2.0500 | 2 | 2 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 2.0500 | 2 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 3.8500 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 105.8800 | 3 | 4 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 9.1250 | 2 | 2 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 4.2400 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 10.3000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 8.9100 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 113.7950 | 3 | 4 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 10.5000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 9.0800 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 7.5900 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 12.7000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 7.0600 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 7.5550 | 2 | 2 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 44.5850 | 2 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.0400 | 3 | 3 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Casein kinase II subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0400 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.0400 | 2 | 2 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.0400 | 2 | 2 |
| Casein kinase II subunit beta | Rattus norvegicus (Norway rat) | IC50 | 0.0400 | 1 | 1 |
| Chain A, Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Chain A, Glutathione S-transferase P1-1 | Homo sapiens (human) | Ki | 11.5000 | 1 | 2 |
| Chain A, GLUTATHIONE TRANSFERASE A1-1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Chain B, Glutathione S-transferase P1-1 | Homo sapiens (human) | Ki | 11.5000 | 1 | 1 |
| Cruzipain | Trypanosoma cruzi | IC50 | 142.0000 | 2 | 2 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 3.3900 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 3.3900 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 3.3900 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 1.0900 | 1 | 1 |
| Cysteine protease ATG4B | Homo sapiens (human) | IC50 | 4.2500 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 4.7700 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 1.9500 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 0.4500 | 1 | 1 |
| DNA polymerase eta | Homo sapiens (human) | IC50 | 0.0620 | 1 | 1 |
| DNA polymerase iota | Homo sapiens (human) | IC50 | 0.0620 | 1 | 1 |
| DNA primase | Mycobacterium tuberculosis CDC1551 | IC50 | 100.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | IC50 | 4.5000 | 1 | 1 |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 1.1050 | 2 | 2 |
| dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 39.5000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | Mus musculus (house mouse) | IC50 | 0.5000 | 1 | 1 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 1.8300 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.6900 | 1 | 1 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 47.6714 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 47.6714 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 3.1100 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 1.0900 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 22.8000 | 1 | 1 |
| Glutathione S-transferase | Plasmodium falciparum 3D7 | IC50 | 74.4000 | 1 | 1 |
| Glutathione S-transferase A1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Glutathione S-transferase Mu 1 | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 32.1000 | 4 | 5 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 7.5000 | 1 | 1 |
| heat shock 70kDa protein 1A | Homo sapiens (human) | IC50 | 66.9200 | 3 | 3 |
| heat shock cognate 71 kDa protein isoform 1 | Homo sapiens (human) | IC50 | 99.6000 | 2 | 2 |
| heat shock cognate 71 kDa protein isoform 2 | Homo sapiens (human) | IC50 | 99.6000 | 2 | 2 |
| Hematopoietic prostaglandin D synthase | Homo sapiens (human) | IC50 | 122.3000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 0.5800 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 1.9800 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | IC50 | 0.3400 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 0.2500 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 5.1000 | 2 | 2 |
| large T antigen | Betapolyomavirus macacae | IC50 | 100.0000 | 1 | 1 |
| likely tRNA 2'-phosphotransferase | Candida albicans SC5314 | IC50 | 0.2913 | 2 | 2 |
| M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 138.0800 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 4.7700 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 1.9500 | 1 | 1 |
| Mcl-1 | Homo sapiens (human) | IC50 | 27.2850 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 8 | Homo sapiens (human) | IC50 | 2.3700 | 1 | 1 |
| mothers against decapentaplegic homolog 3 isoform 1 | Homo sapiens (human) | IC50 | 0.1420 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 4 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 0.5700 | 1 | 3 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 0.5100 | 1 | 1 |
| Nucleophosmin | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 4.1900 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 4.8320 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| Polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens (human) | IC50 | 1.7200 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.4667 | 3 | 3 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 3.3400 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 3.5400 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Renin | Homo sapiens (human) | IC50 | 0.9800 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | Ki | 375.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | Ki | 375.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 375.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 1.7600 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 3.3400 | 1 | 1 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | IC50 | 2.9700 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 2.0000 | 1 | 1 |
| Tat | Human immunodeficiency virus 1 | IC50 | 1.6690 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 176.8000 | 2 | 2 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Translin-associated protein X | Homo sapiens (human) | IC50 | 3.5000 | 1 | 1 |
| Tyrosine-protein kinase Fgr | Rattus norvegicus (Norway rat) | IC50 | 3.5000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Rattus norvegicus (Norway rat) | IC50 | 7.5000 | 1 | 1 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| unnamed protein product | Aspergillus oryzae RIB40 | IC50 | 52.7195 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.7900 | 1 | 1 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 1.5400 | 1 | 1 |
| Vif | Human immunodeficiency virus 1 | IC50 | 0.4500 | 1 | 1 |