tetracycline and Pharyngitis

Actinomycosis is a suppurative infection usually due to a facultative anaerobic bacteria, actinomyces israelii. This rare infection has been reported in immunocompetent individuals, with buccal or pharyngeal mucosal erosions. Paradoxically, few cases have been observed after solid organ transplantation: 2 cases after lung, 1 case after heart-lung transplantation and 1 case after renal transplantation. We report on a renal transplant recipient who developed a tongue and oropharynx suppurative abscess, looking like an epithelioma. Histological examination showed granulomatous inflammation with an angiofibroblastic reaction; few colonies of actinomyces were also observed by the pathologist. This lesion disappeared easily and totally after tetracycline treatment.

Topics: Actinomyces; Actinomycosis; Aged; Anti-Bacterial Agents; Glossitis; Humans; Kidney Transplantation; Male; Pharyngitis; Tetracycline

Chlamydia pneumoniae is the third strain of Chlamydia and transmission is presumed to be by droplet spread from symptomatic patients. The authors show a literature scientific review on subject-matter emphasizing several sporadic and epidemic case of illness in every age, first months excepted. The described cases are few and therefore clinical characteristics are shadowy. Certain clinical features are suggesting of severe pneumonia with fever and pharyngitis without exudate. In the childhood and in the adolescence the clinical evolution is favourable. Tetracyclines or erythromycin is recommended for therapy.

Topics: Age Factors; Child; Child, Preschool; Chlamydophila pneumoniae; Erythromycin; Fever; Fluorescent Antibody Technique; Humans; Infant; Infant, Newborn; Lung; Pharyngitis; Pneumonia; Tetracycline

Of the currently recommended regimens for treatment of uncomplicated gonorrhea, only aqueous penicillin G procaine is effective against infections at all sites. However, procaine penicillin is not effective against penicillinase-producing Neisseria gonorrhoeae and suffers from poor patient acceptability owing to the 10-mL volume of injection and allergic and toxic procaine reactions. Ceftriaxone is a new extended-spectrum cephalosporin with a long serum half-life and is many times more active than penicillin G against both beta-lactamase-positive or -negative strains of N gonorrhoeae. Ceftriaxone was compared as a single, 125-mg, 0.5-mL injection with a single 2-g injection of spectinomycin in difficult to treat pharyngeal gonorrhea in men and women and anorectal gonorrhea of men. Ceftriaxone cured 30/32 (94%) pharyngeal and 52/52 anorectal infections, compared with 6/14 (43%) and 9/9, respectively, for spectinomycin. Both regimens were well tolerated. Ceftriaxone may prove to be a drug of choice for uncomplicated gonorrhea, particularly where homosexual men are treated and/or penicillinase-producing N gonorrhoeae is prevalent.

Topics: Adult; Cefotaxime; Ceftriaxone; Clinical Trials as Topic; Drug Eruptions; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Penicillin G; Pharyngitis; Proctitis; Spectinomycin; Tetracycline

Topics: Adolescent; Adult; Chlorides; Clinical Trials as Topic; Female; Gonorrhea; Humans; Male; Middle Aged; Nausea; Pharyngitis; Sex Factors; Spectinomycin; Tetracycline

Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Erythromycin; Female; Furunculosis; Humans; Male; Middle Aged; Otitis Media; Pharyngitis; Tetracycline

Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Oleandomycin; Pharyngitis; Tetracycline; Tonsillitis

Topics: Adolescent; Adult; Anti-Bacterial Agents; Brazil; Carrier State; Child; Child, Preschool; Drug Resistance, Bacterial; Female; Humans; Macrolides; Male; Pharyngitis; Pharynx; Prospective Studies; Streptococcal Infections; Streptococcus; Tetracycline; Young Adult

The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate the association between episodes of acute pharyngitis and carrier status.. Throat swabs were collected from September to November 2013 among children 5-13 years of age from a rural community (Maria Ignacia-Vela, Argentina). The phenotypic characterization of isolates was performed by conventional tests. Antimicrobial susceptibility was assayed for penicillin, tetracycline, chloramphenicol, erythromycin, and clindamycin (disk diffusion). The minimum inhibitory concentration was determined for penicillin, cefotaxime, tetracycline, and erythromycin.. The carriage of β-hemolytic streptococci was detected in 18.1% of participants, with. The present study demonstrated significant throat carriage of GAS and the presence of group C streptococci (

Topics: Adolescent; Anti-Bacterial Agents; Argentina; Carrier State; Child; Child, Preschool; Drug Resistance, Bacterial; Female; Humans; Macrolides; Male; Microbial Sensitivity Tests; Pharyngitis; Pharynx; Phenotype; Rural Population; Streptococcal Infections; Streptococcus pyogenes; Tetracycline

Macrolides are often used to treat group A streptococcus (GAS) infections, but their resistance rates reached high proportions worldwide. The aim of the present study was to give an update on the characteristics and contemporary prevalence of macrolide-resistant pharyngeal GAS in Central Italy. A total of 592 isolates causing pharyngitis in children were collected in the period 2012-2013. Clonality was assessed by emm typing and pulsed-field gel electrophoresis (PFGE) for all macrolide-resistant strains and for selected susceptible isolates. Genetic determinants of resistance were screened by polymerase chain reaction (PCR). Forty-four GAS were erythromycin-resistant (7.4 %). Among them, 52.3 % and 50 % were clindamycin- and tetracycline-resistant, respectively. erm(B)-positive isolates (52.3 %) expressed the constitutive cMLSB phenotype. mef(A) and its associated M phenotype were recorded in 40.9 % of the cases. The remaining erm(A)-positive isolates expressed the iMLSB phenotype. Seventeen tetracycline-resistant isolates carried tet(M) and five isolates carried tet(O). Twenty-five emm types were found among all strains, with the predominance of emm types 12, 89, 1, and 4. Eleven emm types and 12 PFGE clusters characterized macrolide-resistant strains, with almost two-thirds belonging to emm12, emm4, and emm11. Macrolide-susceptible and -resistant emm types 12, 89, 11, and 4 shared related PFGE profiles. There was a dramatic decline in macrolide resistance in Central Italy among pharyngeal GAS isolates in 2012-2013 when compared to previous studies from the same region (p < 0.05), although macrolide consumption remained stable over the past 15 years. We observed a decrease in the proportion of macrolide-resistant strains within emm types commonly associated with macrolide resistance in the past, namely emm12, 1, and 89.

Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Female; Humans; Italy; Male; Microbial Sensitivity Tests; Pharyngitis; Streptococcal Infections; Streptococcus pyogenes; Tetracycline

Topics: Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Drug Resistance, Microbial; Erythromycin; Humans; Microbial Sensitivity Tests; Pharyngitis; Streptococcal Infections; Streptococcus pyogenes; Tetracycline

The natural history, transmissibility, and treatment of oropharyngeal gonorrhea have been incompletely examined in previous studies. We repeated cultures on 60 patients with untreated pharyngeal gonorrhea, before treatment. The probability that the culture would remain positive decreased progressively as the interval between cultures increased, suggesting self-limited colonization. Gonococci were easily grown from expectorated saliva in 34 of 51 cultures from patients with oropharyngeal gonorrhea, suggesting transmissibility and providing another reason for ensuring effective treatment. Five treatment regimens were evaluated in 292 cases of oropharyngeal gonorrhea. Compared with aqueous procaine penicillin G, single-dose ampicillin and spectinomycin had unacceptably higher failure rates, and oral tetracycline given for 5 or 7 days was shown to be effective. A simple oral regimen providing a second dose of ampicillin plus probenecid 8 to 14 hours after the first dose was also effective.

Topics: Ampicillin; Drug Administration Schedule; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Penicillin G Procaine; Pharyngitis; Pharynx; Probenecid; Retrospective Studies; Saliva; Spectinomycin; Tetracycline

Topics: Adolescent; Adult; Animals; Bird Diseases; Birds; Child; Child, Preschool; Chlamydia Infections; Female; Head; Humans; Infant; Japan; Lymphadenitis; Male; Minocycline; Neck; Pharyngitis; Tetracycline

The records of 1,381 patients with gonorrhea were examined by the Massachusetts Department of Public Health to determine the efficacy of their treatment schedules. Urethritis, cervicitis and pharyngitis were treated with 4.8 million u. of aqueous procaine penicillin G intramuscularly, without probenecid. Cure rates were 98 percent in urethritis, 97 percent in pharyngitis and 98 percent in cervicitis. Patients allergic to penicillin were treated with tetracycline orally or spectinomycin intramuscularly. In patients with proctitis, a 98 percent cure rate was achieved with one intramuscular injection of procaine penicillin G, followed by ampicillin orally for four days.

Topics: Adult; Ampicillin; Drug Administration Schedule; Female; Gonorrhea; Humans; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Penicillin Resistance; Pharyngitis; Proctitis; Spectinomycin; Tetracycline; Urethritis; Uterine Cervicitis

Topics: Adult; Gonorrhea; Humans; Male; Penicillin G Procaine; Pharyngitis; Retrospective Studies; Tetracycline

In many cases gonorrhea is overlooked and not treated due to an unusual course of the disease. The longer this infection exists the greater is the danger of dissemination of the gonococci. Gonorrhea, if not diagnosed, may cause a series of local and general clinical manifestations, such as: the dermatitis-arthritis syndrome whose pathogenesis is not yet completely clarified: the Fitz-Hugh-Curtis syndrome which is often seen in females with chronic gonococcal adnexitis;gonococcal pharyngitis which nowadays occurs more often due to less conventional sexual practices of contemporary society; gonococcal conjunctivitis which represents the best known extragenital gonococcosis. This paper deals with the clinical manifestations and their treatment.

Topics: Adult; Arthritis; Conjunctivitis; Dermatitis; Female; Gonorrhea; Humans; Infant, Newborn; Male; Meningitis; Neisseria gonorrhoeae; Ophthalmia Neonatorum; Penicillins; Pharyngitis; Prognosis; Sepsis; Spectinomycin; Tetracycline

Rhinoscleroma is a chronic granulomatous disease of the respiratory tract endemic to Eastern Europe and Central America which is being recognized with increasing frequency in other countries, including the United States. It was initially described as a lesion of the nose and upper respiratory tract, but is now known to involve the larynx, trachea and bronchi as well to cause slowly progressive asphyxia. Eleven cases of rhinoscleroma with varying degrees of involvement of the lower respiratory tract (larynx, trachea and bronchi) are presented. Present day treatment is both medical, consisting primarily of streptomycin and tetracycline, and endoscopic dilatation. Prolonged medication with careful dose control is necessary. Lower respiratory tract involvement should be considered in patients with chronic destructive granulomatous nasal pathology. This should be especially emphasized if they have an Eastern European or Central American background, or have travelled in these areas in which rhinoscleroma is endemic.

Topics: Adult; Europe; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Laryngitis; Male; Mexico; Middle Aged; Pharyngitis; Recurrence; Rhinitis; Rhinoscleroma; Streptomycin; Tetracycline; Time Factors; United States

Gonorrhea, the nation's second most frequently reported communicable disease, will affect more than a million persons this year. The following is the latest treatment schedule issued by the USPHS Center for Disease Control, Atlanta.

Topics: Adolescent; Ampicillin; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Penicillin G Procaine; Pharyngitis; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Spectinomycin; Sulfides; Tetracycline; Tetrazoles; Thiadiazoles; Urethritis

Topics: Ampicillin; Child; Female; Gonorrhea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Pharyngitis; Probenecid; Spectinomycin; Syphilis; Tetracycline; United States; United States Public Health Service; Urethritis

Antibiotic therapy has been shown to be of no value in the treatment of the URI--either in shortening the course of the acute illness or in preventing the development of secondary bacterial infections. Patient expense, as well as the threat of adverse reactions, should prohibit the present practice by some of routinely prescribing tetracycline, erythromycin, and ampicillin. Indiscriminate antibiotic therapy cannot substitute for proper diagnostic evaluation of the patient who may have either a bacterial or, far more likely, a viral illness.

Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Diagnosis, Differential; Diarrhea; Guaiacol; Humans; Mycoplasma Infections; Otitis Media; Penicillin V; Penicillins; Pharyngitis; Prospective Studies; Respiratory Tract Infections; Streptococcal Infections; Sulfonamides; Tetracycline; Vomiting

Self-treatment with antibiotics was evaluated among patients at a university health service in an 18-month period. Sixty-two students ingested antibiotics, usually tetracycline (40%) or penicillin (21%), for varying intervals before seeking medical care. Respiratory symptoms were the most common reason (40%). The most frequent drug source was residual medication obtained by prescription from a private physician for a prior illness (43%). Although self-therapy was of short duration, the negative bacteriologic cultures obtained on our evaluation in all but four patients challenged precise diagnosis. The findings indicate that inappropriate use of antibiotics by patients would be curtailed by prescribing only the exact amount needed for a given illness and by emphasizing the need for completion of the course of therapy.

Topics: Adult; Ampicillin; Anti-Bacterial Agents; Common Cold; Female; Humans; Male; Penicillins; Pharyngitis; Private Practice; Respiratory Tract Diseases; Self Medication; Students; Substance-Related Disorders; Tetracycline; Vaginitis

Report about cyclic agranulocytosis in a 10 1/2 years old girls, having stomatitis, sore throat and fever up to 39 degrees C in the interval of approximately 3 weeks since the age of 6 months. By the prophylactic treatment with pulverized tetracyclin, which is already given 2 days prior to the expected decrease of the neutrophils, the patient stays clinically asymptomatic since 7 months.

Topics: Agranulocytosis; Bone Marrow Cells; Child; Child, Preschool; Female; Fever; Humans; Infant; Leukocytes; Neutrophils; Periodicity; Pharyngitis; Powders; Punctures; Stomatitis; Tetracycline

Topics: Chlamydia; Chlamydia Infections; Female; Humans; Middle Aged; Pharyngitis; Sexually Transmitted Diseases; Tetracycline

Topics: Adolescent; Adult; Ampicillin; Cervix Uteri; Female; Gonorrhea; Humans; Male; Middle Aged; Military Personnel; Neisseria gonorrhoeae; Netherlands; Penicillin G; Penicillin G Procaine; Pharyngitis; Prostate; Rectum; Tetracycline; Tonsillitis; Urethra

Topics: Adolescent; Adult; Child; Child, Preschool; Clindamycin; Erythromycin; Humans; Penicillins; Pharyngitis; Streptococcal Infections; Tetracycline

Topics: Adult; Age Factors; Cysts; Deglutition Disorders; Diagnosis, Differential; Female; Hemorrhage; Humans; Middle Aged; Pharyngitis; Prednisone; Sex Factors; Tetracycline; Thyroiditis

Topics: Disease Outbreaks; Erythromycin; Humans; Male; Naval Medicine; Penicillin G Benzathine; Penicillin V; Pharyngitis; Ships; Streptococcal Infections; Streptococcus; Tetracycline

Topics: Adult; Child, Preschool; Chronic Disease; Complement Fixation Tests; Female; Gingivitis; Gonorrhea; Homosexuality; Humans; Male; Neisseria; Neisseria gonorrhoeae; Neisseria meningitidis; Paraphilic Disorders; Penicillin G Procaine; Pharyngeal Diseases; Pharyngitis; Pharynx; Prospective Studies; Recurrence; Spectinomycin; Tetracycline; Tonsillitis

Topics: Adult; Cervix Uteri; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Pharyngitis; Pharynx; Probenecid; Rectum; Sexual Behavior; Spectinomycin; Tetracycline

Topics: Abortion, Spontaneous; Arthritis, Rheumatoid; Birth Weight; Erythromycin; Female; Humans; Mouth Diseases; Mycoplasma; Mycoplasma Infections; Pharyngitis; Pregnancy; Tetracycline; Time Factors; Urethritis

Topics: Candidiasis, Vulvovaginal; Female; Gonorrhea; Humans; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Pharyngitis; Proctitis; Syphilis; Tetracycline; Urogenital System; Vulvovaginitis

Topics: Anti-Bacterial Agents; Antibody Formation; Chloramphenicol; Enterocolitis, Pseudomembranous; Humans; Infections; Intestines; L Forms; Pharyngitis; Rickettsia Infections; Salmonella Infections; Staphylococcus; Streptococcus; Streptomycin; Tetracycline; Time Factors

Topics: Adolescent; Blood Transfusion; Cephaloridine; Disseminated Intravascular Coagulation; Female; Fever; Fibrinogen; Heparin; Humans; Infectious Mononucleosis; Pharyngitis; Tetracycline; Trephining; Vomiting

Topics: Adult; Biopsy; Chronic Disease; Humans; L Forms; Male; Necrosis; Pharyngitis; Stomatitis, Aphthous; Streptococcal Infections; Tetracycline; Triamcinolone Acetonide

Topics: Aerosols; Anti-Infective Agents, Local; Humans; Laryngitis; Otitis; Otorhinolaryngologic Diseases; Pharyngitis; Sinusitis; Solutions; Tetracycline; Tonsillitis

Topics: Adolescent; Bronchitis; Child; Child, Preschool; Coagulase; Female; Humans; Male; Mycoplasma Infections; Penicillin V; Pharyngitis; Pneumonia; Pyoderma; Staphylococcus; Suppuration; Tetracycline; Tonsillitis

Topics: Adolescent; Adult; Child; Child, Preschool; Ear Diseases; Female; Furunculosis; Humans; Laryngitis; Male; Middle Aged; Otitis Media; Otorhinolaryngologic Diseases; Pharyngitis; Pyrazoles; Sinusitis; Tetracycline; Tonsillitis

Topics: Acute Disease; Anti-Bacterial Agents; Bronchiolitis, Viral; Bronchitis; Chronic Disease; Cross Infection; Humans; Laryngitis; Penicillin Resistance; Penicillins; Pharyngitis; Pneumonia; Respiratory Tract Infections; Tetracycline; Tracheitis

Topics: Bronchitis; Calcification, Physiologic; Child; Humans; Intracranial Pressure; Kidney; Male; Nervous System; Pharyngitis; Tetracycline

Topics: Asthma; Bronchitis; Child; Child, Preschool; Female; Humans; Infant; Male; Pharyngitis; Pyrazoles; Respiratory Tract Infections; Tetracycline; Tonsillitis

Topics: Bronchitis; Bronchopneumonia; Child; Child, Preschool; Chymotrypsin; Female; Humans; Infant; Lymphadenitis; Male; Pharyngitis; Respiratory Tract Infections; Tetracycline; Trypsin

Topics: Adolescent; Adult; Ampicillin; Drug Hypersensitivity; Erythromycin; Female; Humans; Infectious Mononucleosis; Leukocyte Count; Male; Penicillins; Pharyngitis; Retrospective Studies; Tetracycline

Topics: Penicillin Resistance; Penicillins; Pharyngitis; Rheumatic Fever; Romania; Scarlet Fever; Streptococcal Infections; Streptococcus pyogenes; Tetracycline

Topics: Adult; Culture Media; Gonorrhea; History, 16th Century; History, 19th Century; History, Ancient; Homosexuality; Humans; Male; Penicillin G Procaine; Penicillins; Pharyngitis; Tetracycline

Topics: Bronchitis; Child; Child, Preschool; Female; Humans; Infant; Male; Otitis; Penicillin V; Pharyngitis; Tetracycline

Topics: Adult; Bronchitis; Humans; Male; Middle Aged; Mycoplasma; Pharyngitis; Pneumonia; Tetracycline

Topics: Cholangitis; Erysipelas; Female; Humans; Male; Measles; Pharyngitis; Respiratory Tract Infections; Smallpox; Streptococcal Infections; Tetracycline

Topics: Carrier State; Child; Demeclocycline; Dosage Forms; Drug Resistance; Drug Resistance, Microbial; Humans; Penicillin G; Penicillin V; Pharyngitis; Pharynx; Phosphates; Potassium; Respiratory Tract Infections; Streptococcal Infections; Tetracycline; Tonsillitis

Topics: Anti-Bacterial Agents; Erythromycin; Humans; Penicillins; Pharyngitis; Streptococcal Infections; Sulfadiazine; Sulfamethoxazole; Sulfanilamide; Sulfanilamides; Sulfisoxazole; Sulfonamides; Tetracycline

Topics: Adolescent; Cellulitis; Child; Humans; Oleandomycin; Otitis Media; Otolaryngology; Pharyngitis; Sinusitis; Tetracycline

Topics: Child; Drug Therapy; Fanconi Anemia; Fanconi Syndrome; Metabolic Diseases; Pharyngitis; Protein Synthesis Inhibitors; Tetracycline; Toxicology

Topics: Adolescent; Anti-Bacterial Agents; Biomedical Research; Bronchitis; Child; Drug Therapy; Geriatrics; Infant; Infant, Newborn; Inositol; Novobiocin; Pharyngitis; Phytic Acid; Tetracycline; Toxicology

Topics: Aerosols; Anti-Bacterial Agents; Bacitracin; Bacteriological Techniques; Bronchitis; Chloramphenicol; Diagnosis; Drug Therapy; Humans; Neomycin; Penicillins; Pharyngitis; Pneumonia; Respiratory Tract Infections; Streptomycin; Sulfonamides; Tetracycline; Tracheitis; Virus Diseases

Topics: Child; Dermatology; Focal Infection; Focal Infection, Dental; Humans; Infant; Novobiocin; Otitis; Pediatrics; Pharyngitis; Respiratory Tract Infections; Sinusitis; Tetracycline

Topics: Anti-Bacterial Agents; Chloramphenicol; Listeria; Listeriosis; Penicillins; Pharyngitis; Sulfonamides; Tetracycline

Topics: Anti-Bacterial Agents; Nose; Novobiocin; Otolaryngology; Pharyngitis; Tetracycline

Topics: Anti-Bacterial Agents; Nose; Novobiocin; Otolaryngology; Pharyngitis; Tetracycline

Topics: Child; Disease Outbreaks; Humans; Infant; Pharyngitis; Streptococcal Infections; Streptococcus; Tetracycline