Any salt or ester arising from reaction of the carboxy group of salicylic acid, or any ester resulting from the condensation of the phenolic hydroxy group of salicylic acid with an organic acid.
ChEBI ID: 26596
| Member | Definition | Role |
|---|---|---|
| aspirin | A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. | acetylsalicylic acid |
| bay 93820 | isocarbophos | |
| eterilate | etersalate | |
| glycol salicylate | A benzoate ester obtained by the formal condensation of carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol | 2-hydroxyethyl salicylate |
| isofenphos | isofenphos | |
| methyl salicylate | A benzoate ester that is the methyl ester of salicylic acid. | methyl salicylate |
| phenyl salicylate | A benzoate ester that is the phenyl ester of salicylic acid. Also known as salol, it can be formed by heating salicylic acid with phenol and is used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes. | phenyl salicylate |
| physostigmine salicylate | physostigmine salicylate | |
| salicylsalicylic acid | A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes. | salsalate |
| tosiben | 2,3-diacetyloxybenzoic acid | |
| triflusal | 2-acetyloxy-4-(trifluoromethyl)benzoic acid | |
| valerylsalicylate | A valerate ester that is salicylic acid in which the phenolic hydrogen is replaced by a valeryl (pentanoyl) group. | valerylsalicylic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14,111 (28.92) | 18.7374 |
| 1990's | 7,060 (14.47) | 18.2507 |
| 2000's | 11,093 (22.74) | 29.6817 |
| 2010's | 12,364 (25.34) | 24.3611 |
| 2020's | 4,158 (8.52) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 7,043 (13.53%) | 5.53% |
| Reviews | 7,102 (13.64%) | 6.00% |
| Case Studies | 3,603 (6.92%) | 4.05% |
| Observational | 451 (0.87%) | 0.25% |
| Other | 33,851 (65.04%) | 84.16% |