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7alpha-hydroxy steroid

A 7-hydroxy steroid in which the hydroxy group at position 7 has an alpha-configuration.

ChEBI ID: 36843

Members (16)

MemberDefinitionRole
3,7,12-trihydroxycholestan-26-oic acidA steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions.3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid
3,7,12-trihydroxycoprostane5beta-cholestane-3alpha,7alpha,12alpha-triol
3,7,12-trihydroxycoprostanic acid3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane-5-carboxylic acid
3,7,12,24-tetrahydroxycholestanoic acid3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid
7 alpha-hydroxy-4-cholesten-3-oneA cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C=C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.7alpha-hydroxycholest-4-en-3-one
7-hydroxydehydroepiandrosteroneAn androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position.7alpha-hydroxydehydroepiandrosterone
allocholic acidAn allo-bile acid that is 5alpha-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.allocholic acid
androstane-3,7,17-triolA 3beta sterol that is 5alpha-androstane which is substituted by beta-hydroxy groups at positions 3 and 17 and by an alpha-hydroxy group at position 7.5alpha-androstane-3beta,7alpha,17beta-triol
cholest-5-en-3 beta,7 alpha-diolThe 7alpha-hydroxy derivative of cholesterol.7alpha-hydroxycholesterol
cholestane-3,7,12,26-tetrol5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol
cholic acidA bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.cholic acid
dihydroxycoprostane5beta-cholestane-3alpha,7alpha-diol
glycochenodeoxycholate-3-sulfateA steroid sulfate that is the 3-O-sulfo derivative of glycochenodeoxycholic acid.sulfoglycochenodeoxycholic acid
hydroxysitosterolA 3beta-hydroxy steroid that is sitosterol substituted by an additional alpha-hydroxy group at position 7. It has been isolated from the roots of Breynia fruticosa.stigmast-5-ene-3beta,7alpha-diol
obeticholic acidA dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.obeticholic acid
scymnol5beta-scymnol

Research

Studies (2,491)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990529 (21.24)18.7374
1990's495 (19.87)18.2507
2000's468 (18.79)29.6817
2010's751 (30.15)24.3611
2020's248 (9.96)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials97 (3.69%)5.53%
Reviews143 (5.44%)6.00%
Case Studies36 (1.37%)4.05%
Observational4 (0.15%)0.25%
Other2,350 (89.35%)84.16%