A poison that interferes with the functions of the nervous system.
| Member | Definition | Class |
|---|
| 1-bromopropane | A bromoalkane that is propane carrying a bromo substituent at position 1. | 1-bromopropane |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4. | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| 1-methyl-4-phenylpyridinium | A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position. | N-methyl-4-phenylpyridinium |
| 1,4-butanediol | A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16degreeC) with a high boiling point (230degreeC), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). | butane-1,4-diol |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine | An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. | N-hydroxy-PhIP |
| 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline | An isoquinolinol that is norsalsolinol substituted by a methyl group at position 2. It is present in normal human brain and also identified in the cerebrospinal fluid of patients with Parkinson's disease. | N-methylnorsalsolinol |
| 2,5-hexanedione | A diketone that is hexane substituted by oxo groups at positions 2 and 5. It is a toxic metabolite of hexane and of 2-hexanone | 2,5-hexanedione |
| 3-dinitrobenzene | A dinitrobenzene that is benzene disubstituted at positions 1 and 3 with nitro groups. | 1,3-dinitrobenzene |
| 3-nitropropionic acid | A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group. | 3-nitropropanoic acid |
| 3,4-dihydroxyphenylglycolaldehyde | A hydroxyaldehyde consisting of phenylacetaldehyde having three hydroxy substituents located at the alpha-, 3- and 4-positions. It is a metabolite of noradrenaline. | 3,4-dihydroxymandelaldehyde |
| 4-butyrolactone | A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2. | gamma-butyrolactone |
| 4-hydroxybutyric acid | A 4-hydroxy monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a hydroxy group. | 4-hydroxybutyric acid |
| acromelic acid a | A pyrrolidinecarboxylic acid that is siolated from the poisonous mushroom Clitocybe amoenolens. | acromelic acid A |
| acrylamide | A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia. | acrylamide |
| allyl cyanide | An aliphatic nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an allyl group. | allyl cyanide |
| aminochrome 1 | A member of the class of indoledione that is 2,3,5,6-tetrahydro-1H-indole carrying oxo groups at positions 5 and 6; major microspecies at pH 7.3. It is an endogenous compound formed during dopamine oxidation and can induce neurotoxicity under certain aberrant conditions and induce Parkinson-like syndrome. | dopaminechrome (keto form) |
| ammonium hydroxide | An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. | ammonia |
| beta-n-methylamino-l-alanine | A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a methylamino group. A non-proteinogenic amino acid produced by cyanobacteria, it is a neurotoxin that has been postulated as a possible cause of neurodegenerative disorders of aging such as Alzheimer's disease, amyotrophic lateral sclerosis, and the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS-PDC) syndrome of Guam. | L-BMAA |
| bicuculline | A benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. | bicuculline |
| carbon monoxide | A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. | carbon monoxide |
| decabromobiphenyl ether | A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines. | decabromodiphenyl ether |
| decarbamylsaxitoxin | A pyrrolopurine that is 2,6-diiminodecahydropyrrolo[1,2-c]purine carrying an additional hydroxymethyl substituent at position 4 as well as two hydroxy substituents at position 10. A toxin that is isolated from marine dinoflagellates and cyanobacteria and is known to cause paralytic shellfish poisoning. | decarbamoylsaxitoxin |
| dextroamphetamine | A 1-phenylpropan-2-amine that has S configuration. | (S)-amphetamine |
| dextromethorphan | A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough. | dextromethorphan |
| diethyl phthalate | The diethyl ester of benzene-1,2-dicarboxylic acid. | diethyl phthalate |
| domoic acid | An L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is produced by the diatomic algal Pseudo-nitzschia. It is an analogue of kainic acid and a neurotoxin which causes amnesic shellfish poisoning (ASP). | domoic acid |
| dysiherbaine | A furopyran that is (3aR,7aR)-hexahydro-2H-furo[3,2-b]pyran substituted by carboxy, (2S)-2-amino-2-carboxyethyl, hydroxy and methylamino groups at positions 2, 2, 6, and 7, respectively (the 2R,3aR,6S,7R,7aR-stereoisomer). A convulsant isolated from the marine sponge Dysidea herbacea that has high affinity for kainate ionotropic glutamate receptors. | dysiherbaine |
| edifenphos | An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid. Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates. | edifenphos |
| hemimellitene | A trimethylbenzene carrying methyl groups at positions 1, 2 and 3. It has been found in Centaurium erythraea. | 1,2,3-trimethylbenzene |
| ibotenic acid | | Ibotenic acid |
| ketamine | A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group. | ketamine |
| lead | | lead atom; lead(0) |
| lead chromate | A chromium coordination entity comprising chromate and lead(2+) ions in a 1:1 ratio | lead chromate |
| levodopa | An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease | L-dopa zwitterion; L-dopa |
| megestrol acetate | A sesquiterpene lactone with formula C15H20O8. It is a neurotoxic natural product found in plants of the family Illiciaceae. | anisatin |
| mercury | Elemental mercury of oxidation state zero. | mercury atom; mercury(0) |
| methamphetamine | A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent. | methamphetamine |
| n-butylbenzenesulfonamide | A sulfonamide that is benzenesulfonamide substituted by a butyl group at the nitrogen atom. It has been isolated from the plant Prunus africana and has been shown to exhibit antiandrogenic activity. | N-butylbenzenesulfonamide |
| n-hexane | An unbranched alkane containing six carbon atoms. | hexane |
| n-methyl-3,4-methylenedioxyamphetamine | A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a 2-(methylamino)propyl group at position 5. | 3,4-methylenedioxymethamphetamine |
| nicotine | A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum. | (S)-nicotine |
| oltipraz | A 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively. | oltipraz |
| oxidopamine | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). | oxidopamine |
| phencyclidine | A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects. | phencyclidine |
| potassium cyanide | A cyanide salt containing equal numbers of potassium cations and cyanide anions. | potassium cyanide |
| pseudocumene | A trimethylbenzene carrying methyl groups at positions 1, 2 and 4. | 1,2,4-trimethylbenzene |
| resiniferatoxin | A heteropentacyclic compound found in Euphorbia poissonii with molecular formula C37H40O9. It is an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1). | resiniferatoxin |
| saxitoxin | An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. | saxitoxin |
| t-2 toxin | A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. | T-2 toxin |
| tetrodotoxin | A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. | tetrodotoxin |
| thallium acetate | An acetate salt comprising equal numbers of acetate and thallium ions. | thallium(I) acetate |
| toluene | The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent. | toluene |
| vx | A organic thiophosphate that is the ethyl ester of S-{2-[di(propan-2-yl)amino]ethyl} O hydrogen methylphosphonothioate. A toxic nerve agent used in chemical warfare. | VX nerve agent |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 8.8006 | 2 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 42.1077 | 4 | 11 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 0.6423 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.5267 | 1 | 6 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 21.1546 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 42.1801 | 10 | 29 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 69.4377 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 15.0340 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 6.5131 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 25.6966 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 23.9341 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 25.6966 | 1 | 2 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 23.9341 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 4.1864 | 3 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 43.1449 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 43.1449 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 25.0117 | 2 | 9 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 49.1313 | 2 | 3 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 27.5653 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 14.1254 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 2.1486 | 1 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 48.0224 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 6.4760 | 3 | 7 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 11.6754 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 0.4087 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 2.1486 | 1 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 64.3332 | 2 | 8 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 19.4998 | 3 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 26.8370 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 29.4605 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 21.7540 | 2 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 61.4847 | 1 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.1458 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 19.5957 | 2 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 38.2903 | 2 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 8.7013 | 1 | 5 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 4.1127 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 37.5199 | 10 | 29 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 43.4186 | 2 | 5 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 36.6127 | 6 | 27 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 30.4376 | 1 | 7 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 0.3722 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 15.9641 | 2 | 2 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 23.8972 | 3 | 4 |
| G | Vesicular stomatitis virus | Potency | 26.8370 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 6.4268 | 2 | 8 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 45.8833 | 2 | 9 |
| GLS protein | Homo sapiens (human) | Potency | 28.3627 | 2 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 5.5768 | 5 | 11 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.5623 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 30.4866 | 2 | 3 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.5623 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.5623 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 47.5894 | 2 | 4 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 11.7467 | 2 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 26.8370 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 2.1238 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 17.5594 | 2 | 4 |
| IDH1 | Homo sapiens (human) | Potency | 1.8356 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 65.9411 | 1 | 3 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 26.8370 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 28.1838 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 26.8370 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 47.3079 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 10.9945 | 1 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 11.9310 | 1 | 4 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 32.1968 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 7.5193 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 21.5757 | 2 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 5.4744 | 2 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 44.8440 | 4 | 11 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 29.3550 | 1 | 4 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.5638 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 19.9526 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 37.5313 | 3 | 13 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 44.4073 | 2 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 2.6137 | 1 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 56.2755 | 3 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 46.6664 | 2 | 2 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 12.1739 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 69.8119 | 3 | 5 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 46.3776 | 2 | 8 |
| progesterone receptor | Homo sapiens (human) | Potency | 56.9281 | 2 | 5 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 32.7586 | 2 | 7 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 1.0618 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 35.4692 | 3 | 13 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 29.3128 | 3 | 14 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 19.4998 | 3 | 3 |
| Smad3 | Homo sapiens (human) | Potency | 13.9353 | 1 | 3 |
| snurportin-1 | Homo sapiens (human) | Potency | 65.9411 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 13.5904 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 23.0412 | 2 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 31.6944 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 34.2470 | 2 | 6 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 17.9789 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 20.1742 | 4 | 14 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 30.1475 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 20.7491 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 52.1423 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 22.2786 | 4 | 6 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 72.6796 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 45.4488 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 5.4979 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | Ki | 71.0000 | 1 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | IC50 | 11.0000 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | IC50 | 4.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | Ki | 2.7000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | IC50 | 0.0025 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | Ki | 3.3139 | 4 | 4 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | Ki | 8.1350 | 2 | 2 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Ki | 0.2236 | 7 | 8 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 10.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 2.4526 | 2 | 2 |
| Alcohol dehydrogenase E chain | Equus caballus (horse) | Ki | 7,762.4700 | 1 | 1 |
| Alcohol dehydrogenase S chain | Equus caballus (horse) | Ki | 7,762.4700 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | Ki | 0.0007 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 14.4000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | Ki | 1,487.5000 | 3 | 4 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 353.3333 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 336.6667 | 2 | 3 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 278.1667 | 3 | 6 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Ki | 4.3000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | Ki | 19.4333 | 3 | 3 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.0000 | 1 | 1 |
| Cholinesterase | Mus musculus (house mouse) | Ki | 0.5224 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 4,100.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 9.0000 | 1 | 1 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Ki | 72.0000 | 1 | 1 |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | IC50 | 159.9560 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 210.6763 | 2 | 3 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 46.2667 | 3 | 3 |
| Cytochrome P450 2B6 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 264.0000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 5.6000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 18.6000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 136.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 2.1768 | 5 | 5 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 12.9000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 26.3000 | 1 | 1 |
| Delta-aminolevulinic acid dehydratase | Escherichia coli K-12 | Ki | 44,900.0000 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.4400 | 1 | 1 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.1100 | 1 | 1 |
| Dihydropteridine reductase | Homo sapiens (human) | IC50 | 5,100.0000 | 2 | 2 |
| DNA repair protein RAD52 homolog | Homo sapiens (human) | IC50 | 0.7790 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 451.4400 | 2 | 2 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | IC50 | 0.9380 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 502.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 76.0000 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 76.0000 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 76.0000 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 76.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | Ki | 0.0007 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 2.5687 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | Ki | 0.5153 | 7 | 9 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 13.4966 | 7 | 9 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 0.2790 | 17 | 18 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 2.2158 | 4 | 5 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | Ki | 0.5153 | 7 | 9 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 13.4966 | 7 | 9 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 0.2848 | 16 | 17 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 3.1569 | 2 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 15.0587 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | Ki | 0.5572 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 0.2848 | 16 | 17 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 15.0587 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | Ki | 0.5572 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 0.2935 | 17 | 18 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 15.0587 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | Ki | 0.5572 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 0.2914 | 15 | 16 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 15.0587 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | Ki | 0.5572 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 0.2914 | 15 | 16 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 15.0587 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | Ki | 0.5572 | 6 | 8 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 0.2914 | 15 | 16 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 0.5939 | 2 | 2 |
| Isocitrate lyase | Candida albicans | IC50 | 32.6164 | 11 | 11 |
| Isocitrate lyase | Mycobacterium tuberculosis H37Rv | IC50 | 116.0000 | 1 | 1 |
| Isocitrate lyase 1 | Mycobacterium tuberculosis CDC1551 | IC50 | 14.7000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 0.5939 | 2 | 2 |
| Liver carboxylesterase B-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0450 | 1 | 1 |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | IC50 | 0.0910 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 43.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 110.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 1,000.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 17.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.2260 | 2 | 2 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.4400 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | Ki | 2.1100 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 1.0597 | 2 | 2 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 360.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.0595 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.0438 | 27 | 28 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 0.3899 | 4 | 4 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 6.2120 | 5 | 5 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.3763 | 20 | 20 |
| Neuronal acetylcholine receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 0.0841 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.2178 | 37 | 42 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 0.3456 | 10 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | IC50 | 0.0055 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Gallus gallus (chicken) | Ki | 0.0019 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.3444 | 30 | 30 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.0204 | 72 | 85 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 | 14.3000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | IC50 | 0.0087 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Ki | 5.9317 | 17 | 19 |
| Neuronal acetylcholine receptor subunit alpha-7 | Mus musculus (house mouse) | Ki | 0.2406 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 3.1729 | 16 | 20 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | IC50 | 0.0041 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | IC50 | 0.3256 | 11 | 13 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0046 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.3399 | 30 | 30 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | Ki | 0.0024 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.0124 | 76 | 85 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | IC50 | 0.0848 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0050 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 0.0012 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.0070 | 3 | 4 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | IC50 | 0.7150 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | IC50 | 0.0040 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | IC50 | 6.2120 | 5 | 5 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | Ki | 0.3463 | 22 | 22 |
| Neuronal acetylcholine receptor subunit beta-4 | Mus musculus (house mouse) | Ki | 0.0572 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 0.1748 | 54 | 63 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | Ki | 435.3333 | 2 | 3 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 24.0000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 2.2580 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 217.2290 | 6 | 7 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 65,000.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 0.4150 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | IC50 | 0.1236 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.5300 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | Ki | 0.0365 | 2 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 3.2527 | 3 | 3 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | Ki | 3.0800 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 0.0023 | 1 | 1 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 5.6500 | 2 | 2 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 0.0010 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 5.6500 | 2 | 2 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 0.0130 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 5.6500 | 2 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 620.0106 | 4 | 5 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 0.2100 | 1 | 1 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 0.4100 | 1 | 1 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 0.0011 | 1 | 1 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 0.3931 | 4 | 4 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 0.0120 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 1.3928 | 3 | 4 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.5030 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.8591 | 3 | 4 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.2495 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 3.5505 | 5 | 6 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 1.0600 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 9.1134 | 5 | 6 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 1.0900 | 1 | 4 |
| Soluble acetylcholine receptor | Aplysia californica (California sea hare) | Ki | 1.0466 | 3 | 3 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | IC50 | 141,200.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 26.0333 | 2 | 3 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 12.7250 | 2 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 12.3000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 2.4000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 26.1500 | 1 | 2 |
| Solute carrier family 22 member 3 | Rattus norvegicus (Norway rat) | IC50 | 248.0000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 54.0000 | 1 | 1 |
| Synaptic vesicular amine transporter | Rattus norvegicus (Norway rat) | Ki | 41.2800 | 2 | 2 |
| Tetraspanin | Rattus norvegicus (Norway rat) | IC50 | 15.8000 | 2 | 2 |
| Translocator protein | Rattus norvegicus (Norway rat) | Ki | 0.5063 | 2 | 4 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 2.7755 | 2 | 2 |
| Tyrosinase | Homo sapiens (human) | IC50 | 8,400.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 2.1460 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 3.7290 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Kd | 4.4668 | 1 | 2 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | EC50 | 25.3333 | 3 | 3 |
| Acetylcholine receptor subunit alpha | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit beta | Homo sapiens (human) | EC50 | 29.0000 | 3 | 3 |
| Acetylcholine receptor subunit beta | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine receptor subunit delta | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit delta | Tetronarce californica (Pacific electric ray) | EC50 | 110.0000 | 2 | 2 |
| Acetylcholine receptor subunit epsilon | Homo sapiens (human) | EC50 | 65.0000 | 1 | 1 |
| Acetylcholine receptor subunit gamma | Homo sapiens (human) | EC50 | 33.0000 | 2 | 2 |
| Acetylcholine receptor subunit gamma | Tetronarce californica (Pacific electric ray) | EC50 | 60.0000 | 1 | 1 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Kd | 0.2931 | 3 | 5 |
| Chain A, Immunoglobulin | Mus musculus (house mouse) | Kd | 0.0020 | 1 | 1 |
| Chain A, Pheromone-binding protein ASP1 | Apis mellifera (honey bee) | Kd | 0.0390 | 1 | 6 |
| Chain B, Immunoglobulin | Mus musculus (house mouse) | Kd | 0.0020 | 1 | 1 |
| Chain B, Pheromone-binding protein ASP1 | Apis mellifera (honey bee) | Kd | 0.0390 | 1 | 2 |
| Cytochrome P450 2A13 | Homo sapiens (human) | Kd | 54.0000 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Kd | 470.0000 | 1 | 1 |
| Endolysin | Tequatrovirus T4 | Kd | 248.6667 | 6 | 6 |
| Glycoprotein IIb | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| Integrin beta | Oryctolagus cuniculus (rabbit) | EC50 | 1.5068 | 1 | 4 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 43.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 110.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 1,000.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Mus musculus (house mouse) | Kd | 9.1000 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | Kd | 9.1000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | EC50 | 40.6667 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 21.3260 | 14 | 15 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 3.1424 | 20 | 24 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | EC50 | 10.7398 | 12 | 12 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 30.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-6 | Homo sapiens (human) | EC50 | 0.1270 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | EC50 | 55.2158 | 6 | 6 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | EC50 | 3,948.0836 | 10 | 11 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | Kd | 0.0011 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | EC50 | 9.3127 | 23 | 27 |
| Neuronal acetylcholine receptor subunit beta-2 | Mus musculus (house mouse) | EC50 | 0.7222 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 10.7398 | 12 | 12 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-3 | Homo sapiens (human) | EC50 | 10.5635 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | EC50 | 35.5000 | 2 | 2 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | EC50 | 13.6576 | 14 | 15 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | EC50 | 30.2517 | 7 | 8 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Kd | 14,352.0000 | 3 | 3 |
| ORF73 | Human gammaherpesvirus 8 | EC50 | 75.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 0.9900 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | EC50 | 0.1515 | 1 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | EC50 | 0.9950 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 0.7100 | 2 | 3 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | EC50 | 104.9157 | 4 | 5 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | EC50 | 0.9185 | 1 | 2 |
| Taste receptor type 2 member 46 | Homo sapiens (human) | EC50 | 31.0000 | 1 | 1 |
| Trace amine-associated receptor 1 | Homo sapiens (human) | EC50 | 0.9108 | 4 | 6 |
| Trace amine-associated receptor 1 | Macaca mulatta (Rhesus monkey) | EC50 | 3.1550 | 1 | 2 |
| Trace amine-associated receptor 1 | Mus musculus (house mouse) | EC50 | 0.3628 | 5 | 10 |
| Trace amine-associated receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 0.7424 | 6 | 11 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 152,369.0000 | 2 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| Transporter | Rattus norvegicus (Norway rat) | EC50 | 51.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 11.4000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 11.4000 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Km | 311.3333 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | Km | 325.1667 | 6 | 6 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 0.9600 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 39.0000 | 1 | 1 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 11.4000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 90.0000 | 2 | 2 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 43.3000 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 23.3000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 3.1000 | 11 | 11 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 1.6700 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 43.0000 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 12.1000 | 1 | 1 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 6.5000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ka | 11.4000 | 13 | 13 |
| Carbonic anhydrase 3 | Homo sapiens (human) | KA | 13.5000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ka | 15.3000 | 2 | 2 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 0.0360 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 0.0630 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ka | 18.0000 | 2 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 58.3000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 51.3000 | 1 | 1 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 0.8300 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Km | 8.1600 | 5 | 5 |
| Delta-type opioid receptor | Mus musculus (house mouse) | K0.5 | 26.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | K0.5 | 0.2500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 58.3000 | 1 | 1 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | K0.5 | 26.0000 | 1 | 2 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 6,430.0000 | 1 | 1 |
| Mu-type opioid receptor | Mus musculus (house mouse) | K0.5 | 26.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | Mus musculus (house mouse) | K0.5 | 30.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Mus musculus (house mouse) | K0.5 | 30.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | Mus musculus (house mouse) | K0.5 | 30.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M4 | Mus musculus (house mouse) | K0.5 | 30.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M5 | Mus musculus (house mouse) | K0.5 | 30.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
| Nuclear factor erythroid 2-related factor 2 | Mus musculus (house mouse) | CD | 10.2000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 0.0630 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 860.0000 | 1 | 1 |
| POU domain, class 2, transcription factor 2 | Homo sapiens (human) | Km | 2.7000 | 1 | 1 |
| SLC16A10 protein | Homo sapiens (human) | Km | 1,212.5000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | Km | 10.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Km | 8.6750 | 4 | 4 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Activity | 33.6333 | 2 | 3 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Km | 14.6000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Activity | 7.8000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Km | 14.8800 | 4 | 5 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | Km | 24.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Km | 14.4667 | 3 | 3 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Km | 47.0000 | 1 | 1 |
| Solute carrier family 22 member 3 | Rattus norvegicus (Norway rat) | Km | 57.5000 | 2 | 2 |
| Transporter | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 1 |