A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 43.6486 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 27.8298 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 3.1623 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 41.1929 | 2 | 2 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 32.6113 | 3 | 6 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 30.8249 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 30.8249 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 21.8075 | 1 | 2 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 31.6228 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 16.7761 | 1 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.1120 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 4.3649 | 1 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 22.9727 | 2 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0062 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 46.9600 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 21.7792 | 4 | 10 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 43.2331 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 42.8185 | 5 | 7 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 24.2520 | 1 | 4 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 19.1163 | 3 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 54.8805 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 15.1120 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 3.9102 | 2 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.2434 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 54.9410 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.4885 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 29.9312 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 79.9034 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.1120 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 48.9123 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.1120 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 15.0320 | 2 | 3 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 2.4058 | 1 | 4 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 17.3598 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 44.1136 | 4 | 7 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 11.2202 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 43.5469 | 3 | 4 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 69.6219 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 34.1846 | 2 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 49.3684 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 41.2146 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 56.3458 | 2 | 5 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.2783 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 0.9439 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 54.5477 | 2 | 3 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 6.9066 | 2 | 5 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 18.8876 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 19.8942 | 2 | 4 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 89.1251 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.7810 | 3 | 7 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 70.7373 | 3 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 48.0224 | 1 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 46.2293 | 2 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 0.0016 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.4885 | 1 | 1 |