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17-oxo steroid

Any oxo steroid carrying the oxo group at position 17.

ChEBI ID: 19168

Members (30)

MemberDefinitionRole
1,4-androstadiene-3,17-dioneA steroid that consists of androstane having double bonds at positions 1 and 4 and two keto groups at positions 3 and 17.androsta-1,4-diene-3,17-dione
1,5(10)-estradiene-3,4,17-trioneAn o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 4-hydroxyestrone.estra-1,5(10)-diene-3,4,17-trione
16-hydroxydehydroepiandrosterone16alpha-hydroxydehydroepiandrosterone
19-hydroxy-4-androstene-3,17-dione19-hydroxyandrost-4-ene-3,17-dione
19-norandrosterone19-norandrosterone
19-oxo-delta(4) androstene-3,17-dioneAn androstanoid that is androst-4-en-19-al substituted by oxo groups at positions 3 and 17.3,17-dioxoandrost-4-en-19-al
2-methoxyestroneA 17-oxo steroid that is estrone in which the hydrogen at position 2 has been replaced by a methoxy group.2-methoxyestrone
4-hydroxyestroneA 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4.4-hydroxyestrone
5-androstene-3,17-dioneAn androstanoid that is androst-5-ene bearing two oxo substituents at positions 3 and 17.androst-5-ene-3,17-dione
7-hydroxydehydroepiandrosteroneAn androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position.7alpha-hydroxydehydroepiandrosterone
7-oxodehydroepiandrosteroneA 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7.7-ketodehydroepiandrosterone
9-hydroxy-4-androstene-3,17-dioneA 3-oxo-Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17 and a hydroxy group at position 9.9alpha-hydroxyandrost-4-en-3,17-dione
adrenosteroneA 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17.adrenosterone
androsta-1,4,6-triene-3,17-dioneAn androstanoid that is androsta-1,4,6-triene substituted by oxo groups at positions 3 and 17.androsta-1,4,6-triene-3,17-dione
androstenedioneA 3-oxo Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.androst-4-ene-3,17-dione
androsteroneAn androstanoid that is 5alpha-androstane having a hydroxy substituent at the 3alpha-position and an oxo group at the 17-position. It is a metabolite of dehydroepiandrosterone .androsterone
androsterone sulfateA steroid sulfate that is the 3-sulfate of androsterone.androsterone sulfate
aromasilA 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.exemestane
dehydroepiandrosteroneAn androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.dehydroepiandrosterone
dehydroepiandrosterone sulfateA steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.dehydroepiandrosterone sulfate
epiandrosteroneA 3beta-hydroxy steroid that is (5alpha)-androstane substituted by a beta-hydroxy group at position 3 and an oxo group at position 17.epiandrosterone
epietiocholanoloneA 3beta-hydroxy steroid that is 5beta-androstane substituted by a hydroxy group at position 3beta and an oxo group at position 17. It is a metabolite of testosterone.epietiocholanolone
equileninA 3-hydroxy steroid that is estrone which carries two double bonds at positions 6 and 8. It is found in the urine of pregnant mare's and extensively used for estrogen replacement therapy in postmenopausal women.equilenin
equilinequilin
estra-1(10),4-diene-2,3,17-trioneAn o-quinone resulting from the formal oxidation of the dihydroxyphenyl moiety of 2-hydroxyestrone.estra-1(10),4-diene-2,3,17-trione
estroneA 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17.estrone
estrone sulfateA steroid sulfate that is the 3-sulfate of estrone.estrone 3-sulfate
estrone-3-glucuronideThe 3-beta-D-glucuronide of estrone.estrone 3-O-(beta-D-glucuronide)
etiocholanoloneAn androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.3alpha-hydroxy-5beta-androstan-17-one
formestaneA 17-oxo steroid that is androst-4-ene-3,17-dione in which the hydrogen at position 4 is replaced by a hydroxy group. Formestane was the first selective, type I steroidal aromatase inhibitor, suppressing oestrogen production from anabolic steroids or prohormones. It was formerly used in the treatment of oestrogen-receptor positive breast cancer in post-meopausal women. As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. It fell out of use with the subsequent development of cheaper, orally active aromatase inhibitors. Formestane is listed by the World Anti-Doping Agency as a substance prohibited from use by athletes.formestane

Research

Studies (27,901)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199012,555 (45.00)18.7374
1990's4,246 (15.22)18.2507
2000's5,306 (19.02)29.6817
2010's4,501 (16.13)24.3611
2020's1,293 (4.63)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials2,357 (6.15%)5.53%
Reviews2,116 (5.52%)6.00%
Case Studies888 (2.32%)4.05%
Observational86 (0.22%)0.25%
Other32,884 (85.79%)84.16%